EC Number   |
Activating Compound |
Reference |
|---|
   2.8.2.4 | 17-hydroxy-19-nor-7-methyl-17-pregn-5(10)-en-20-yn-3-one |
- |
645898 |
| 2.8.2.4 | 17-hydroxy-19-nor-7-methyl-17-pregn-5(10)-en-20-yn-3-one |
Org OD14, active substance in Livial (R), 0.0005-0.00005 mM stimulates the formation of estrone by 40-60%, no effect in MDA-MB-231 cells |
645897 |
| 2.8.2.4 | 2-mercaptoethanol |
activation |
645869, 645870 |
| 2.8.2.4 | 3alpha-hydroxy-tibolone |
biphasic effect, inhibits at high concentrations, but stimulates at low concentrations, in MCF-7 and T4-7D cells, overview |
671361 |
| 2.8.2.4 | 3alpha-tibolone |
activates SULT1E1 in MCF-7 cells by 50% and 37% at low concentrations of 50 nM and 500 nM, respectively, inhibits at 0.05 mM by 63% |
671361 |
| 2.8.2.4 | 3beta-hydroxy-tibolone |
biphasic effect, inhibits at high concentrations, but stimulates at low concentrations, in MCF-7 and T4-7D cells, overview |
671361 |
| 2.8.2.4 | 3beta-hydroxytibolone |
102% stimulation of activity at 0.0005 mM |
701711 |
| 2.8.2.4 | 3beta-tibolone |
activates SULT1E1 in MCF-7 cells by 101% and 74% at low concentrations of 50 nM and 500 nM, respectively, inhibits at 0.05 mM by 54% |
671361 |
| 2.8.2.4 | 4-ene-tibolone |
- |
671361 |
| 2.8.2.4 | cAMP |
enzyme activity is induced by |
645901 |
