EC Number   |
Activating Compound |
Reference |
|---|
    2.7.7.15 | activator protein-1 |
potential regulator of CCTbeta2 expression in neuronal cells |
691071 |
| 2.7.7.15 | conduritol-B-epoxide |
treatment of macrophages with 0.5 mM conduritol-B-epoxide results in elevated activity of CCT |
691467 |
| 2.7.7.15 | diphosphatidylglycerol |
- |
690911 |
| 2.7.7.15 | dithiothreitol |
20 mM |
642896 |
| 2.7.7.15 | fatty acids |
activity slightly enhanced by addition of saturated fatty acids, markedly increased by addition of unsaturated fatty acids regardless of chain length and number of double bonds |
642893 |
| 2.7.7.15 | glucosylceramide |
- |
660981 |
| 2.7.7.15 | Lipids |
regulation of activity by reversible association with membrane lipids |
660981, 662320, 662451, 662689, 663437 |
| 2.7.7.15 | Lipids |
regulation of activity by reversible association with membrane lipids, activation of enzyme when bound to lipid vesicles, vesicles containing 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine or egg phosphatidylglycerol are more effective than vesicles containing 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 1,2-dioleoyl-sn-glycerol, or egg phosphatidylcholine |
661213 |
| 2.7.7.15 | Lipids |
regulation of activity by reversible association with membrane lipids, preferentially activated by anionic lipids, highest activation with phosphatidylcholine vesicles containing diphosphatidylglycerol (29fold), less activation with vesicles containing phosphatidylserine (16fold), phosphatidylinositol (21fold), phosphatidylethanolamine (17fold), and oleate (13fold), compared to free enzyme 5fold activation with enzyme associated with pure phosphatidylcholine vesicles |
661238 |
| 2.7.7.15 | Lipids |
regulation of activity by reversible association with membranes containing anionic lipids |
662237, 662364 |
