EC Number   |
Activating Compound |
Reference |
|---|
   2.7.12.2 | anisomycin |
activates |
491891 |
| 2.7.12.2 | CD40 |
activated by ligation of CD40, the B-cell antigen receptor |
491828 |
| 2.7.12.2 | doxycycline |
induces expression of HA-MEK1 |
681836 |
| 2.7.12.2 | growth factor interleukin-3 |
activates |
491828 |
| 2.7.12.2 | more |
activated by GTP-Cdc42 or GTP-Rac1 in vitro |
491925 |
| 2.7.12.2 | more |
activation in vivo in response to serum, phosphorylation and activation by the v-Raf protein in vitro |
491872 |
| 2.7.12.2 | more |
activation is induced by epidermal growth factor tyrosine protein kinase and nucelar growth factor tyrosine protein kinase |
490796 |
| 2.7.12.2 | more |
dissociation factor DF induces MEK1/2 and ERK1/2 expression |
666517 |
| 2.7.12.2 | more |
enzyme is activated by environmental stress and physiological stimuli. In hematopoietic cells, endogenous MKK7 is activated by treatment with the growth factor interleukin-3, or by ligation of CD40, the B-cell antigen receptor, or the receptor for the Fc fragment of immunoglobulin. MKK7 is also activated when cells are exposed to heat, UV irradiation, anisomycin, hyperosmolarity or the pro-inflammatory cytokine tumor necrosis factor-alpha |
491828 |
| 2.7.12.2 | more |
enzyme ZmMKK1 interacts with enzyme ZmMEKK1 as determined in yeast two-hybrid assays |
740902 |
