EC Number   |
Activating Compound |
Reference |
|---|
   2.7.11.22 | 2,5-hexanedione |
CDK5 contents and activities in sciatic nerve of rats treated with 200 or 400 mg/kg 2,5-hexanedione are significantly increased in both the cytosolic and membrane fractions, increase of CDK5 content in both the cytosolic and membrane fractions of spinal cord in 200 and 400 mg/kg 2,5-hexanedione-treated rats are observed |
695204 |
| 2.7.11.22 | beta-amyloid peptide25-35 |
- |
691554 |
| 2.7.11.22 | Calmodulin |
Ca2+/calmodulin induce the phosphorylation of p35 by Cdk5 after stimulation of the Ca2+-permeable cation channels NMDA receptor and kainate receptor, leading to cleavage of p35 to p25 |
666117 |
| 2.7.11.22 | CDC25 phosphatase |
major activator of CDK2 |
691105 |
| 2.7.11.22 | Cdc25A |
- |
679989 |
| 2.7.11.22 | CDK-activating kinase |
the CDK-activating kinase (having three subunits, CDK7, cyclin H, and MAT1) plays a critical role in regulating cell cycle by mediating the activating phosphorylation of CDK1, CDK2, CDK4, and CDK6 |
707985 |
| 2.7.11.22 | CHAPS |
the detergent increases Cdk5-p35 activity with histone H1 and the autophosphorylation at p35 |
666120 |
| 2.7.11.22 | Cks2 |
Cks 2 proteins activates Cdk2 |
723656 |
| 2.7.11.22 | Clbp1-Clbp6 |
cyclins, possible regulatory subunits of Cdc28p, each influencing the enzyme activity in a distinct way, overview |
666340 |
| 2.7.11.22 | Cyc2 |
- |
737994 |
