EC Number |
Activating Compound |
Reference |
---|
2.7.11.2 | 2-oxoisopentanoate |
- |
642136, 642137, 642139, 94884 |
2.7.11.2 | 2-oxoisopentanoate |
only in the presence of K+ and thiamine diphosphate, kinetics |
642143 |
2.7.11.2 | acetoacetyl-CoA |
slight activation |
642139 |
2.7.11.2 | acetyl-CoA |
- |
642136, 642137, 642159, 642164, 94884 |
2.7.11.2 | acetyl-CoA |
activates the enzyme, especially isozyme PDK2 |
642164 |
2.7.11.2 | acetyl-CoA |
domain-specific binding, isozymes PDK2 and PDK3 |
642157, 642164 |
2.7.11.2 | acetyl-CoA |
high stimulation through acetylation of the transacetylase-catalyzing inner core portion of the dihydrolipoyl acetyltransferase |
642149 |
2.7.11.2 | acetyl-CoA |
involved in the regulation of enzyme activity regulating pyruvate dehydrogenase complex |
642149, 642150 |
2.7.11.2 | acetyl-CoA |
isozyme PDK2: addition of K+ and Cl- required, phosphate increases the stimulating effect |
642159 |
2.7.11.2 | acetyl-CoA |
kinase bound to transacetylase core |
642151, 642154 |