EC Number   |
Activating Compound |
Reference |
|---|
    2.7.1.21 | 3'-azido-2',3'-dideoxy-3,4-dihydrothymidine |
stimulates deoxycytidine phosphorylation catalyzed by thymidine kinase 2 |
723302 |
| 2.7.1.21 | 3'-azido-3'-deoxythymidine |
stimulates deoxycytidine phosphorylation catalyzed by thymidine kinase 2 |
723302 |
| 2.7.1.21 | 3'-deoxy-3'-fluorothymidine |
stimulates deoxycytidine phosphorylation catalyzed by thymidine kinase 2 |
723302 |
| 2.7.1.21 | 3'-fluorothymidine |
stimulates deoxycytidine phosphorylation catalyzed by thymidine kinase 2 |
723302 |
| 2.7.1.21 | ATP |
- |
641168 |
| 2.7.1.21 | ATP |
binding of ATP induces enzyme tetramerization, which leads to activation of the enzyme, the dimeric enzyme form is probably less active, 50-100% activation at up to 5 mM |
660865 |
| 2.7.1.21 | bovine serum albumin |
activation at 0.2 mg/ml |
641116 |
| 2.7.1.21 | Calmodulin |
stimulates the enzyme by 13.8%, might modify the activity, enzyme contains a calmodulin binding domain, Ca2+ is required for binding, compounds W7 and W13 prevent stimulation, overview |
660905 |
| 2.7.1.21 | dCDP |
activation |
641132 |
| 2.7.1.21 | dCDP |
dCDP activates the enzyme 2.5old |
722671 |
