EC Number   |
Activating Compound |
Reference |
|---|
   2.4.1.80 | c-Fos |
activity of glucosylceramide synthase is around 5fold higher in presence of high c-Fos levels, induced by nerve growth factor NGF, addition of c-Fos mRNA ASO, which specifically blocks c-Fos expression abolished the induction of glucosylceramide synthase by NGF |
704444 |
| 2.4.1.80 | CHAPS |
i.e. 3-[(3-cholamidopropyl)dimethylamonio]-1propanesulfonate |
489407, 489409, 489410 |
| 2.4.1.80 | cycloserine |
induction |
489420 |
| 2.4.1.80 | detergent |
- |
489404 |
| 2.4.1.80 | detergent |
absolute requirement for |
489404 |
| 2.4.1.80 | detergent |
activity is reduced by most of the detergents tested, only CHAPS and CHAPSO at concentration of 1% w/v stimulate |
489407 |
| 2.4.1.80 | detergent |
CHAPS stimulates |
489410 |
| 2.4.1.80 | detergent |
optimal activity obtained with a mixture of Cutsum and Triton X-100 (2:1) |
489404 |
| 2.4.1.80 | dioleoyl phosphatidylcholine |
or other exogenous phospholipid, required for activity |
489414, 489416 |
| 2.4.1.80 | HSP70 |
dog heat shock protein 70 increases production of glucosylceramide to 149% |
703917 |
