EC Number   |
Activating Compound |
Reference |
|---|
    2.4.1.17 | 17alpha-ethynylestradiol |
slightly activates the 3-beta-glucuronidation of estradiol to 116% at 0.005 mM, but inhibits it at 0.1 mM by 23% |
690683 |
| 2.4.1.17 | 3-methylcholanthrene |
induces glucuronidation of planar phenols |
488777 |
| 2.4.1.17 | 3-methylcholanthrene |
marked induction of hepatic microsomal UDPGT activity, sevenfold increase in the rate of 4-methylumbelliferone glucuronidation, more than 3fold increase towards 4-nitrophenol and fourfold increase towards 1-naphthol |
488725 |
| 2.4.1.17 | 3-methylcholanthrene |
several-fold activity enhanced of 1-naphthol, 4-nitrophenol, N-hydroxy-2-naphtylamine and 3-hydroxy benzo[a]pyrene |
488698 |
| 2.4.1.17 | alamethicin |
- |
658522 |
| 2.4.1.17 | alamethicin |
0.05 mg//g protein, 8fold increase in activity |
674230 |
| 2.4.1.17 | alamethicin |
a pore-forming peptide, activates the activity of liver microsomes, but not of purified recombinant isozyme, with substrates dexmedetomidine and levomedetomidine |
692037 |
| 2.4.1.17 | Alkyl ketones |
activation |
488730 |
| 2.4.1.17 | arctigenin |
about 210% activity of isoform UGT1A8 at 0.1 mM arctigenin |
757950 |
| 2.4.1.17 | arctiin |
about 225% activity of isoform UGT1A8 at 0.1 mM arctiin |
757950 |
