EC Number   |
Activating Compound |
Reference |
|---|
    2.1.1.17 | 1-methyl-4-phenylpyridinium |
enhances activity. S-Adenosylmethionine hypermethylation can be involved in the etiology of Parkinsons disease and an increase of phospholipid methylation could be one of the mechanisms by which 1-methyl-4-phenyl-pyridinium causes parkinsonism |
485188 |
| 2.1.1.17 | betaine |
attenuates alcoholic steatosis by restoring phosphatidylcholine generation via the phosphatidylethanolamine methyltransferase pathway, the effect is enhanced by ethanol, which alone has no effect on expression levels of the enzyme, overview |
675185 |
| 2.1.1.17 | ethanol |
enhances the inducing and protecting effects of betaine on the enzyme, alone has only a slightly activating effect on the enzyme activity, overview |
675185 |
| 2.1.1.17 | L-Cys |
enhances activity, optimal concentration 10 mM |
485175, 485176 |
| 2.1.1.17 | more |
17-beta-estradiol induces the enzyme in hepatocytes |
697842 |
| 2.1.1.17 | more |
light-activation is mediated by transducin |
485194 |
| 2.1.1.17 | progesterone |
physiological levels of progesterone activate PE-NMT and sphingomyelin synthase |
719189 |
| 2.1.1.17 | Triton X-100 |
enhances activity, optimal concentration 0.04% |
485175, 485176 |
| 2.1.1.17 | Tween 20 |
stimulates |
485190 |
