EC Number   |
Activating Compound |
Reference |
|---|
   1.2.1.30 | dithiothreitol |
stimulation of the reduction of the intermediate benzoyladenosine 5'-monophosphate to benzaldehyde |
288180 |
| 1.2.1.30 | more |
for activation, CARs require PPTase-mediated post-translational modification of the T-domain. Through the activity of PPTase, a phosphopantetheine arm is covalently bound to a highly conserved serine domain in the T-domain. The flexibility and length of this phosphopantetheine arm enables this activated residue to transition between the A- and R-domain active sites |
763297 |
| 1.2.1.30 | more |
for activation, CARs require PPTase-mediated posttranslational modification of the T-domain. Through the activity of PPTase, a phosphopantetheine arm is covalently bound to a highly conserved serine domain in the T-domain. The flexibility and length of this phosphopantetheine arm enables this activated residue to transition between the A- and R-domain active sites |
763297 |
| 1.2.1.30 | more |
levels of recombinant Car and Gdh are slightly higher when cultures are grown without chloramphenicol |
692118 |
| 1.2.1.30 | phosphopantetheine transferase |
required for activating the enzyme. Recombinant car is an apoenzyme that requires phosphopantetheinylation for conversion to a fully active holoenzyme |
693019 |
