EC Number   |
Activating Compound |
Reference |
|---|
    1.14.15.4 | 2-oxoglutarate |
most potent activator in intact mitochondria |
285387 |
| 1.14.15.4 | fumarate |
increase of activity |
285387 |
| 1.14.15.4 | KCN |
slight |
285388 |
| 1.14.15.4 | lipid extract |
from adrenocortical mitochondria, increase of aldosterone production from corticosterone |
285402 |
| 1.14.15.4 | malate |
plus NADP+ and in synergism with ascorbate plus NADH increase of aldosterone synthetase activity in zona glomerulosa, no stimulation of 11beta-/18-hydroxylation |
285400 |
| 1.14.15.4 | MnCl2 |
1 mM, reactivation of dialysed enzyme |
285387 |
| 1.14.15.4 | MnCl2 |
causes most of activity to disappear in crude extracts |
285388 |
| 1.14.15.4 | more |
adrenocorticotrophin induces the enzyme in central nervous system tissues, adrenal ectomy does only slightly increase enzyme expression, overview |
688009 |
| 1.14.15.4 | more |
genes amh and cyp11b are both upregulated during juvenile ovary-to-testis transformation |
686286 |
| 1.14.15.4 | more |
polychlorinated biphenyl 126 induces CYP11B1 and CYP11B2 expression, 3',4'-dimethoxyflavone synergistically increases the stimulatory effects of PCB126, PCB126 has little effects on the transcription rate of both genes, but protects both RNA transcripts from degradation, mechanism of up-regulation, overview |
673348 |
