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EC Number Activating Compound Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.29estrogen overexpression of PI3K or Akt significantly increases estrogenic upregulation of CYP7B1 in Hep-G2 cells. Estrogen receptor interacts with the PI3K/Akt pathway without binding to the CYP7B1 gene. In HEK293 cells, CYP7B1 transcription is much less affected by Akt, indicating that the mechanism for upregulation of CYP7B1 is different in different cell types 705397
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