EC Number |
Activating Compound |
Reference |
---|
1.14.14.17 | 2-heptyl-4-hydroxyquinoline N-oxide |
0.1 mM, 236% stimulation |
438203 |
1.14.14.17 | 2-hydroxyethyl jasmonate |
up-regulation of squalene expoxidase gene transcription |
694930 |
1.14.14.17 | Mega-9 |
0.3%, 44% activation |
438207 |
1.14.14.17 | more |
105000 g supernatant, 8.5fold activation of microsomal enzyme, 3fold activation of N-terminal truncated recombinant enzyme |
438206 |
1.14.14.17 | more |
2 cytoplasmic components can be replaced by Triton X-100 |
438195 |
1.14.14.17 | more |
enzyme is not a cytochrome P-450 enzyme |
438199 |
1.14.14.17 | more |
purification of a soluble 47000 Da activator of liver squalene epoxidase |
438194 |
1.14.14.17 | more |
reconstitution of squalene epoxidase activity by addition of: NADPH-cytochrome P-450 reductase, EC 1.6.2.4, FAD and Triton X-100 |
438196, 438199 |
1.14.14.17 | more |
soluble protein factor from hog liver stimulates activity |
438204 |
1.14.14.17 | more |
squalene epoxidation system requires a supernatant protein and a phospholipid: requirement for the heat-stable factor can be fully met by phosphatidylserine, phosphatidylglycerol or phosphatidylinositol and partially by other phospholipids, the heat-labile factor required is a protein with 44000 Da |
438192 |