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EC Number
Activating Compound
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Reference
1.14.13.148
chlorpromazine
the activity of the native enzyme is increased at 0.001-0.2 mM of chlorpromazine. Greatest activation is 85% when methimazole and chlorpromazine concentrations are 2 mM and 0.1 mM, respectively
348510
1.14.13.148
imipramine
the activity of the native enzyme is increased at 0.05-0.75 mM of imipramine
348510
1.14.13.148
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n-octylamine has no effect on isoform FMO3
717752
1.14.13.148
O2
when the oxygen in the enzyme assay mixture is replaced with 100% nitrogen, there is no formation of N,N,N-trimethylamine N-oxide, showing that the enzyme is oxygen-dependent
717521
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