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Results 1 - 7 of 7
EC Number Activating Compound Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.65ascorbate - 744861, 745951, 753164
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.65ascorbate required 746537
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.65fisetin fisetin induces DNA damage via critical transcription factor RFXAP/KDM4A-dependent histone H3K36 demethylation, thus causing inhibition of proliferation in pancreatic adenocarcinoma (PDAC). Fisetin inhibits cell proliferation and induces DNA damage and S-phase arrest in PDAC. Expression of RFXAP and other DNA-damage response genes is upregulated by fisetin. RFXAP targets KDM4A. Overexpression of RFXAP upregulates KDM4A and attenuates methylation of H3K36, impairing DNA repair and enhancing the DNA damage induced by fisetin 764436
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.65HP1a Suv(Var)3-9/KMT1 interacts with HP1 that binds [histone H3]-N6,N6-trimethyl-L-lysine9 701212
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.65more interleukin-1beta enhances recruitment of LSD1 to mPGES-1 promoter 744188
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.65more local demethylation of H3K9me2 is triggered by recruitment of liganded estrogen receptor ERalpha to chromatin 701223
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.65tetrahydrofolate binding kinetic analysis of folate derivatives, e.g. folates bound to glutamates, the (6R,S) form of the natural pentaglutamate form of tetrahydrofolate bound with the highest affinity to full-length LSD1, binding of different forms of folate to LSD1, and binding structures, overview 752751
Results 1 - 7 of 7