EC Number   |
Activating Compound |
Reference |
|---|
   1.11.2.2 | 5-aminosalicylic acid |
converts inactive myeloperoxidase compound II rapidly into active myeloperoxidase |
711274 |
| 1.11.2.2 | ascorbic acid |
200% activation at 0.002 mM and pH 5.2 |
439757 |
| 1.11.2.2 | ascorbic acid |
converts inactive myeloperoxidase compound II into active myeloperoxidase |
711274 |
| 1.11.2.2 | betanin |
low micromolar betanin concentrations enhance the chlorination activity of MPO at pH 7.0, increasing the betanin concentration up to 0.006 mM dramatically increases the chlorination rate of monochlorodimedon |
711064 |
| 1.11.2.2 | chloride |
in the presence of 100 mM NaCl the catalytic efficiency of MPO increases 3-4fold whatever the sulfide considered, the rate of 4-tolyl methyl sulphide oxidation enhancement is about 8fold at 120 mM NaCl |
711125 |
| 1.11.2.2 | D-penicillamine |
addition of D-penicillamine significantly enhances the rate of chloroacetonitrile oxidation and cyanide release by the myeloperoxidase/H2O2/Cl- system (17.2% increase at 5 mM) |
713543 |
| 1.11.2.2 | ferrocyanide |
converts inactive myeloperoxidase compound II into active myeloperoxidase |
711274 |
| 1.11.2.2 | glutathione |
addition of glutathione significantly enhances the rate of chloroacetonitrile oxidation and cyanide release by the myeloperoxidase/H2O2/Cl- system (24% increase at 5 mM) |
713543 |
| 1.11.2.2 | indicaxanthin |
at neutral pH and depending on their concentration, indicaxanthin can exhibit a stimulating and inhibitory effect on the chlorination activity of MPO |
711064 |
| 1.11.2.2 | L-cysteine |
addition of L-cysteine significantly enhances the rate of chloroacetonitrile oxidation and cyanide release by the myeloperoxidase/H2O2/Cl- system (45.4% increase at 5 mM) |
713543 |
