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Results 1 - 10 of 15 > >>
EC Number
Activating Compound
Commentary
Reference
cetyltrimethylammonium bromide
0.1 and 1 mM
Cl-
activation, optimal NaCl concentration for the brain enzyme in hydrolysis of LVVYPWTQRY is 10 mM, optimal concentration for hydrolysis of angiotensin I is 200 mM
Cl-
kcat increases with increasing KCl concentrations, reaches a maximum at about 300 mM KCl, and the begins to decrease. At relatively low concentrations chloride anions activate the C-domain of the enzyme, but at high concentrations chloride inhibits the enzyme activity. Presence of at least two chloride-binding sites in the C-domain of bovine enzyme: binding of chloride to one of the sites causes activation of the enzyme, whereas chloride binding to the second site results in inhibition of the enzymatic activity
Cl-
nonessential activator over the pH range 5.0-10.0
Cl-
required for hydrolysis of angiotensin I, not required for hydrolysis of bradykinin
Diazoacetylnorleucine methyl ester
1.0 mM, activation to 115% of control
diisopropylphosphoryl fluoride
1.0 mM, activation to 116.3% of control
Results 1 - 10 of 15 > >>