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EC Number
Activating Compound
at 1%
it enhances the enzyme activity 2fold at 50°C and 3 M, and 1.5fold at 45°C and 1-3 M, while it reduces the enzyme activity at 35-40°C, by 20% at 40°C and 3 M, about 5% at 1 M, overview
cyclic AMP-dependent protein kinase
phosphorylation, 40% activation of triolein hydrolyzing activity
increase in enzyme activity (130%) is observed at 25% v/v DMSO although at a higher concentration (50%), DMSO decreases enzyme activity to 72%
at 1%
HSL inhibitor
reduced activity in macrophage foam cells due to increased activity of an inhibitor protein
L-methionine enhances the enzyme activity in absence of tumor necrosis factor-alpha, but inhibits it in presence of TNF-alpha
activity in incubated soleus muscle increases in response to adrenaline
proline does not activate and thermally stabilize the enzyme at 35-50°C and concentrations of 1-3 M, but inhibits the enzyme activity
stearate and palmitate, saturated fatty acids but not unsaturated fatty acids (oleate and linoleate) induce up-regulation of HSL mRNA in a time- and concentration-dependent manner in bMEC. Oleate and linoleate induce no up-regulation of HSL mRNA
Results 1 - 10 of 25 > >>