EC Number   |
Activating Compound |
Reference |
|---|
   2.7.3.3 | acetate |
5.5% activation at 50 mM |
673167 |
| 2.7.3.3 | ATP |
about 80% of the activity formerly inhibited by phenylglyoxal is retained by incubating with 20 mM ATP |
674042 |
| 2.7.3.3 | ATP |
after treatment with 10 mM ATP, the enzyme activity significantly increases |
703776 |
| 2.7.3.3 | sucrose |
maintains the activity of the enzyme in the presence of guanidine hydrochloride |
674041 |
| 2.7.3.3 | more |
not affected by sodium nitroprusside, methylene blue and benznidazole |
673489 |
| 2.7.3.3 | dithiothreitol |
once treated with 5,5'-dithiobis-2-nitrobenzoic acid, the enzyme activity can be recovered more than 95% after incubation for 20 min with 0.15 mM dithiothreitol |
674042 |
| 2.7.3.3 | nifurtimox |
produces 2.3fold increase in enzyme expression at 0.01 mM |
673489 |
| 2.7.3.3 | hydrogen peroxide |
produces up to 10fold increase in enzyme expression at 0.2 mM |
673489 |
| 2.7.3.3 | glycerol |
protects arginine kinase from inactivation in both low and high concentrations of guanidine hydrochloride |
674041 |
| 2.7.3.3 | DMSO |
protects arginine kinase from inactivation losing its native tertiary conformation and aggregation in the presence of guanidine hydrochloride |
674041 |
