EC Number   |
Activating Compound |
Reference |
|---|
   2.7.11.10 | NEMO |
- |
661547 |
| 2.7.11.10 | TNF-alpha |
- |
691616 |
| 2.7.11.10 | TNFalpha |
activates histone H3 phosphorylation activity, TNFalpha-induced activation of IKK-beta but not IKK-alpha leads to rapid NFkappaB activation and subsequent degradation of IkappaB |
662942 |
| 2.7.11.10 | CD28 |
activates Vav-1/IKKalpha and subsequently NFkappaB, meditated by Vav-1 |
662568 |
| 2.7.11.10 | more |
aldosterone regulates IKKbeta activity by enzyme induction |
662274 |
| 2.7.11.10 | alloferon |
alloferon, a 13-amino acid peptide isolated from the bacteria-challenged larvae of the blow fly Calliphora vicina, activates IKK activity |
694134 |
| 2.7.11.10 | TNFalpha |
and other cytokines, activation of IKK activating NF-kappaB |
662516 |
| 2.7.11.10 | more |
Bcl10 degradation depends on NEMO and CARMA1 |
676906 |
| 2.7.11.10 | TAK1 |
critical direct upsteam activating kinase of IKK |
703737 |
| 2.7.11.10 | more |
cytokine-induced activation of IKK, e.g. by TNFalpha, required for NFkappaB activation, leads to rapid degradation of IkappaB |
662942 |
