EC Number   |
Activating Compound |
Reference  |
|---|
    2.4.2.30 | DNA |
absolute requirement |
637991, 637993 |
| 2.4.2.30 | GDP |
increases activity in absence of Mg2+ |
637994 |
| 2.4.2.30 | GTP |
increases activity in absence of Mg2+ |
637994 |
| 2.4.2.30 | GTP(gammaS) |
increases activity in absence of Mg2+ |
637994 |
| 2.4.2.30 | ATP |
5-10 mM, 20-30% stimulation |
637995 |
| 2.4.2.30 | 4-[[[6-cyano-1-[(1-methyl-1H-imidazol-5-yl)methyl]-1,2,3,4,6,7-hexahydroquinolin-3-yl](pyridin-2-ylsulfonyl)amino]methyl]-N,N-dimethylpiperidine-1-carboxamide |
activates in presence of Mg2+, inhibits in absence of Mg2+ |
637997 |
| 2.4.2.30 | harmaline hydrochloride |
activates more strongly in absence of Mg2+ than in presence of Mg2+ |
637997 |
| 2.4.2.30 | Phthalic acid |
activates more strongly in absence of Mg2+ than in presence of Mg2+ |
637997 |
| 2.4.2.30 | DNA |
required |
637998 |
| 2.4.2.30 | DNA |
the enzyme is completely dependent on the presence of DNA containing single or double stranded breaks. Activation results in a decondensation of chromatin superstructure in vitro, which is caused mainly by hyper(ADP-ribosyl)ation of histone H1 |
637999 |
