6.5.1.8	C100A	inactive for ligation reaction	-, 741323	
6.5.1.8	C122A	the mutant does not bind Mn2+	749256	
6.5.1.8	C78A	almost complete loss of activity	740694	
6.5.1.8	C78A	completely inactive	748103	
6.5.1.8	C78S	complete loss of activity	740694	
6.5.1.8	C98A	mutation in predicted metal-binding site, loss of activity	740053	
6.5.1.8	D75A	almost complete loss of activity	740694	
6.5.1.8	D75A	the mutation allows cyclic phosphodiester hydrolysis but cripples 3'-phosphate guanylylation	748103	
6.5.1.8	D75E	complete loss of activity	740694	
6.5.1.8	D75N	complete loss of activity	740694