3.4.24.85	D148A	mutant exhibits markedly compromised protease activity	682860	
3.4.24.85	D402N	abolished activity	644083	
3.4.24.85	D467N	mutation of aspartate abolish activity suggesting that is the third residue that coordinates the zinc active site of S2P	644080	
3.4.24.85	E23Q	abolished activity	644083	
3.4.24.85	E55A	mutant exhibits markedly compromised protease activity	682860	
3.4.24.85	H22F	abolished activity	644083	
3.4.24.85	H22F	active site mutant	720919	
3.4.24.85	H26F	abolished activity	644083	
3.4.24.85	H54A	mutant exhibits markedly compromised protease activity	682860	
3.4.24.85	H54A/D148A	mutant exhibits markedly compromised protease activity	682860