3.1.3.67 380-385A in endothelial cells transfected with 380-385A (mutation on the PTEN phosphorylation site) phosphatidylinositol 3,4,5-trisphosphate immunofluorescence intensity is than in wildtype or G129R transfected cells. Phosphatidylinositol 3,4,5-trisphosphate intensity in endothelial cells transfected with 380–385A is weak but gradually increases to a maximum at 240 min after cyclic strain stimulation by 1.48fold relative to static condition 681020 3.1.3.67 A121P inactive mutant enzyme 650767 3.1.3.67 C105F inactive mutant enzyme 650767 3.1.3.67 C124R inactive mutant enzyme 650767 3.1.3.67 C124S adenovirus encoding a dominant negative human PTEN cDNA is used for the transduction of cell cultures 692556 3.1.3.67 C124S catalytically inactive mutant enzyme 650763 3.1.3.67 C124S catalytically inert mutant enzyme 653626 3.1.3.67 C124S complete loss of activity towards inositol 1,3,4,5-tetrakisphosphate 651881 3.1.3.67 C124S mutant PTEN-C124S-A4-YFP lacks lipid and protein phosphatase activity, great localization to the plasma membrane than other mutants 694916 3.1.3.67 C124S phosphatase-deficient 705669