2.3.1.129	G189S	Escherichia coli strain SM101 is deficient in LpxA activity due to a G189S inactivating mutation. Enzymatic activity is restored when the mutant strain is transformed with a wild-type bearing plasmid is inactive	706784	
2.3.1.129	G52L/R58L	residue tolerance in the beta-helical domain: mutation is tolerated	706784	
2.3.1.129	G52V/R58V	residue tolerance in the beta-helical domain: mutation is tolerated	706784	
2.3.1.129	G52W/R58W	residue tolerance in the beta-helical domain: mutation is tolerated	706784	
2.3.1.129	G57P/N51P	residue tolerance in the beta-helical domain: mutation is not tolerated	706784	
2.3.1.129	H122A	lower specific activity than wild-type	486258	
2.3.1.129	H122N	lower specific activity than wild-type	486258	
2.3.1.129	H125A	H125 is an important residue at the active site its mutation eliminates activity. Mutant shows significant growth reduction after introduction into Escherichia coli strain SM101 bearing a defective LpxA gene (G189S), and under novobiocin supplementation	706784	
2.3.1.129	H125A	lower specific activity than wild-type	486258	
2.3.1.129	H125N	lower specific activity than wild-type	486258