2.1.1.137 C10S activtiy similar to wild-type 757684 2.1.1.137 C10S/C11S/C193S/C268S mutant dispays activity 757684 2.1.1.137 C11S activity similar to wild-type 757684 2.1.1.137 C145S loss of catalytic activity 757684 2.1.1.137 C165S inactive 721074 2.1.1.137 C174A the mutation leads to loss of As(III) methylation 718946 2.1.1.137 C186S mutation abolishes the capability of As(III) methylation 757317 2.1.1.137 C193S activity similar to wild-type 757684 2.1.1.137 C195S loss of catalytic activity 757684 2.1.1.137 C210S inactive 721074