1.11.2.3 D70A the disruption of calcium-binding in this mutant abolishes the interaction with the heterotrimeric G-protein complex GPA1. The mutant has altered leaf development 765579 1.11.2.3 E81R the disruption of calcium-binding in this mutant abolishes the interaction with the heterotrimeric G-protein complex GPA1. The mutant has altered leaf development 765579 1.11.2.3 H138V the mutant possess only 4% of the heme content wild type isoform PXG1 712359 1.11.2.3 H70V the heme content of the mutant is barely measurable (less than 1%) as compared to the wild type isoform PXG1 712359