4.2.1.108 C105A site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme -, 749081 4.2.1.108 C105S site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme -, 749081 4.2.1.108 D91A site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme 749081 4.2.1.108 D91E site-directed mutagenesis, the mutant shows similar activity as the wild-type enzyme 749081 4.2.1.108 E115A site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme 749081 4.2.1.108 E115D site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme 749081 4.2.1.108 E57A site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme -, 749081 4.2.1.108 E57D site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme 749081 4.2.1.108 F107A site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme 749081 4.2.1.108 F107W site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme 749081