4.1.3.16 C257G natural mutation associated with Primary Hyperoxaluria type 3. Mutant is quite unstable, has a tendency to aggregate, and retains no measurable activity 721727 4.1.3.16 DeltaE315 natural mutation associated with Primary Hyperoxaluria type 3. Mutant is quite unstable, has a tendency to aggregate, and retains no measurable activity 721727 4.1.3.16 G287V natural mutation associated with Primary Hyperoxaluria type 3. Mutant is quite unstable, has a tendency to aggregate, and retains no measurable activity 721727 4.1.3.16 G287V the mutation is associated with primary hyperoxaluria type 3 748294 4.1.3.16 K196A complete loss of activity 723542 4.1.3.16 N78A 20% of wild-type activity 723542 4.1.3.16 N78Q 4% of wild-type activity 723542 4.1.3.16 N78T 45% of wild-type activity 723542 4.1.3.16 P190L natural mutation associated with Primary Hyperoxaluria type 3. Mutant is quite unstable, has a tendency to aggregate, and retains no measurable activity 721727 4.1.3.16 P190L the mutation is associated with primary hyperoxaluria type 3 748294