3.1.3.56 C214S site-directed mutagenesis, mutation in the P-loop, the mutant shows altered substrate specificities and activities compared to the wild-type enzyme, overview -, 751120 3.1.3.56 C409S decreased activity 646397 3.1.3.56 C409S predominantly soluble 646395 3.1.3.56 C939S eliminates isoprenylation of enzyme which reduces activity towards phosphatidylinositol 4,5-bisphosphate 646393 3.1.3.56 D232A no activity 646400 3.1.3.56 D232A traces of activity 646400 3.1.3.56 D384A no activity 646400 3.1.3.56 D771A no activity 646400 3.1.3.56 D838G no activity 646402 3.1.3.56 DELTA1-119 no significant influence on localization of enzyme 646399