3.1.1.106	C199A	the mutant shows about 90.4% of wild type activity	751029	
3.1.1.106	D122A	the mutant shows about 24.5% of wild type activity	751029	
3.1.1.106	D160A	the mutant shows about 57% of wild type activity	751029	
3.1.1.106	D167A	the mutant shows about 68.7% of wild type activity	751029	
3.1.1.106	D184A	the mutant shows about 39.3% of wild type activity	751029	
3.1.1.106	D35A	the mutant shows strongly reduced activity compared to the wild type enzyme	751419	
3.1.1.106	D77N/D78N	hydrolysis of O-acetyl-D-ADP-ribose is abolished by these mutations	752026	
3.1.1.106	E238Q/E239Q	the mutant shows wild type hydrolytic activity with O-acetyl-D-ADP-ribose	752026	
3.1.1.106	E261Q/E262Q	the mutant shows wild type hydrolytic activity with O-acetyl-D-ADP-ribose	752026	
3.1.1.106	G100E	the mutant isoform MacroD2 lacks hydrolase and ADP-ribose-binding activities	751688