2.7.4.14	E448G	site-directed mutagenesis	693063	
2.7.4.14	G21A	mutant enzyme is degraded during the purification phase	645158	
2.7.4.14	G22A	mutant enzyme with decreased turnover-number/KmATP value. Turnover-number is 59% of that of the wild-type enzyme	645158	
2.7.4.14	G24A	mutant enzyme with decreased turnover-number/KmATP value. Turnover-number is 48% of that of the wild-type enzyme	645158	
2.7.4.14	G26A	mutant enzyme with decreased turnover-number/KmATP value	645158	
2.7.4.14	G27R	mutant enzyme is degraded during the purification phase. Turnover-number is 45% of that of the wild-type enzyme	645158	
2.7.4.14	K27E	mutant enzyme with 2600fold decreased turnover-number/KmATP value. Turnover-number is 21% of that of the wild-type enzyme	645158	
2.7.4.14	K27M	mutant enzyme with 1000fold decreased turnover-number/KmATP value. Turnover-number is 22% of that of the wild-type enzyme	645158	
2.7.4.14	additional information	construction of a UMP-CMPK2DELTA21 mutant lacking the mitochondrial targeting sequence	693063	
2.7.4.14	additional information	determination and analysis of 28 polymorphisms in DCK/CMPK enzymes, genotyping with humans of different ethnic origins, overview. Variant allozyme enzyme activities range from 32 to 105% of the wild-type enzyme for DCK and from 78 to 112% of wild-type enzyme for CMPK, with no significant differences in apparent Km values for either enzyme except for a DCK Val24/Ser122 double variant allozyme, overview	692040