2.7.1.86 G183R mutant with partially retained NADH kinase activity 662376 2.7.1.86 H231D the mutant exhibits no activity towards NAD+ and low activity for NADH 722719 2.7.1.86 R293H the mutation reduces the ratio of NADH kinase activity to NAD kinase activity from 8.6 to 2.1 722719 2.7.1.86 R293H/H231D inactive 722719