2.7.4.13	D16N	site-directed mutagenesis of the P loop-related residue, the mutant shows reduced activity and altered substrate specificity compared to the wild-type enzyme	739645	
2.7.4.13	D170N	site-directed mutagenesis of the core residue, almost inactive mutant	739645	
2.7.4.13	E176Q	site-directed mutagenesis of the core residue, almost inactive mutant	739645	
2.7.4.13	G137A	site-directed mutagenesis of the dNMP-binding residue, the mutant shows highly reduced activity and altered substrate specificity compared to the wild-type enzyme	739645	
2.7.4.13	K131E	site-directed mutagenesis, of the dNMP-binding residue, the mutant shows slightly increased activity and altered substrate specificity compared to the wild-type enzyme	739645	
2.7.4.13	additional information	all enzyme mutants but T17S show an increased pH optimum compared to the wild-type enzyme	739645	
2.7.4.13	Q134A	site-directed mutagenesis of the dNMP-binding residue, the mutant shows reduced activity and altered substrate specificity compared to the wild-type enzyme	739645	
2.7.4.13	R130K	site-directed mutagenesis of the dNMP-binding residue, almost inactive mutant	739645	
2.7.4.13	R172I	site-directed mutagenesis of the core residue, almost inactive mutant	739645	
2.7.4.13	S13A	site-directed mutagenesis of the P loop-related residue, the mutant shows reduced activity and altered substrate specificity compared to the wild-type enzyme	739645	
2.7.4.13	T138A	site-directed mutagenesis of the dNMP-binding residue, the mutant shows reduced activity and altered substrate specificity compared to the wild-type enzyme	739645	
2.7.4.13	T17N	site-directed mutagenesis of the P loop-related residue, the mutant shows highly reduced activity and altered substrate specificity compared to the wild-type enzyme	739645	
2.7.4.13	T17S	site-directed mutagenesis, of the P loop-related residue, the mutant shows reduced activity compared to the wild-type enzyme	739645	
2.7.4.13	W150A	site-directed mutagenesis of the core residue	739645	
2.7.4.13	W150F	site-directed mutagenesis of the conserved residue, the mutant shows unaltered activity compared to the wild-type enzyme	739645