2.4.1.252	E287A	mutant enzyme loses activity in vivo and in vitro	
2.4.1.252	E295A	mutant enzyme retains residual activity in the in vivo assay	
2.4.1.252	H127A	retains reduced but significant activity both in vitro and in vivo	
2.4.1.252	K211A	mutant enzyme loses activity in vivo and in vitro	
2.4.1.252	S162A	retains reduced but significant activity both in vitro and in vivo