2.1.1.85	N255A	the mutant has increased lysine methylation activity and decreased histidine methylation activity compared to the wild type enzyme	757747	
2.1.1.85	N255V	the mutant has increased lysine methylation activity and decreased histidine methylation activity compared to the wild type enzyme	757747	
2.1.1.85	N256A	the mutant shows severely reduced activity compared to the wild type enzyme	756580	
2.1.1.85	N256D	the mutant shows severely reduced activity compared to the wild type enzyme	756580	
2.1.1.85	N256Q	the mutant shows about 50% activity compared to the wild type enzyme	756580	
2.1.1.85	N278A	the mutant shows severely reduced activity compared to the wild type enzyme	756580	
2.1.1.85	R215A	the mutant shows severely reduced activity compared to the wild type enzyme	756580	
2.1.1.85	R316A	the mutant shows severely reduced activity compared to the wild type enzyme	756580	
2.1.1.85	R75A	the mutant shows severely reduced activity compared to the wild type enzyme	756580	
2.1.1.85	Y312A	catalytical mutant with residual activity	757802	
2.1.1.85	Y313F	the mutant shows severely reduced activity compared to the wild type enzyme	756580