1.14.13.54	K295A	the mutant is 3times more active than the wild type enzyme	
1.14.13.54	L500Y	the mutant is about 2.5times more active than the wild type enzyme	
1.14.13.54	P157Q	the mutant shows wild type activity	
1.14.13.54	T345L	the mutation turns the enzyme inactive against progesterone without altering the catalytic efficiency for phenylacetone	
1.14.13.54	V291A	the mutant is less active than the wild type enzyme