1.1.98.2 E109Q the mutant has 60fold decreased catalytic efficiency compared to the wild type enzyme 740083 1.1.98.2 H40A the mutant has 1000fold decreased catalytic efficiency compared to the wild type enzyme 740083 1.1.98.2 K197N the mutant shows strongly reduced catalytic efficiency compared to the wild type enzyme 739925 1.1.98.2 K258N the mutant shows strongly reduced catalytic efficiency compared to the wild type enzyme 739925 1.1.98.2 R282Q the mutant shows severely reduced catalytic efficiency compared to the wild type enzyme 739925 1.1.98.2 W44A the mutant has 2000fold decreased catalytic efficiency compared to the wild type enzyme 740083 1.1.98.2 W44F the mutant has 2fold increased catalytic efficiency compared to the wild type enzyme 740083 1.1.98.2 W44Y the mutant has 34fold decreased catalytic efficiency compared to the wild type enzyme 740083