4.2.1.108 F107W site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme 749081 4.2.1.108 F107Y site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme 749081 4.2.1.108 H117A site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme -, 749081 4.2.1.108 H55A site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme 749081 4.2.1.108 H93A site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme 749081 4.2.1.108 H93N site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme 749081 4.2.1.108 L87A site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme 749081 4.2.1.108 S23A site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme 749081 4.2.1.108 T40A site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme 749081 4.2.1.108 W21A site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme 749081