3.4.21.47	E207A	mutation in proenzyme factor B. Mutation disrupts salt bridge R234-E207, with little effects on the cleavage of proenzyme factor B	717849	
3.4.21.47	E301A	mutation in the Bb component decreases sensitivity to DAF to 75% of the wild-type value	652225	
3.4.21.47	E316A	mutation in the Bb component decreases sensitivity to DAF to 71% of the wild-type value	652225	
3.4.21.47	E379A	mutation in the Bb component decreases sensitivity to DAF to 52% of the wild-type value, sensitivity to CR1 to 50% of the wild-type value	652225	
3.4.21.47	E434A	mutation in the Bb component decreases sensitivity to CR1 to 65% of the wild-type value	652225	
3.4.21.47	E446V	mutation in proenzyme factor B. Mutation disrupts salt bridge R234-E446 which partly stabilizes the complex C3bB(Mg2+) thereby inhibiting activation of the proenzyme	717849	
3.4.21.47	F716A	factor B mutation, severly reduces hemolytic activity	36600	
3.4.21.47	K265A/K266A	Mutation in the Bb component decreases sensitivity to DAF to 18% of the wild-type value, sensitivity to CR1 to 18% of the wild-type value and sensitivity to Factor H to 19% of the wild-type value	652225	
3.4.21.47	K294A	mutation in the Bb component decreases sensitivity to CR1 to 44% of the wild-type value	652225	
3.4.21.47	M341A	mutation in the Bb component decreases sensitivity to Factor H to 75% of the wild-type value	652225