3.4.22.1	cathepsin B	-	
3.4.22.2	papain	-	
3.4.22.3	ficain	-	
3.4.22.6	chymopapain	-	
3.4.22.7	asclepain	-	
3.4.22.8	clostripain	-	
3.4.22.10	streptopain	-	
3.4.22.14	actinidain	-	
3.4.22.15	cathepsin L	-	
3.4.22.16	cathepsin H	-	
3.4.22.24	cathepsin T	-	
3.4.22.25	glycyl endopeptidase	-	
3.4.22.26	cancer procoagulant	-	
3.4.22.27	cathepsin S	-	
3.4.22.28	picornain 3C	-	
3.4.22.29	picornain 2A	-	
3.4.22.30	Caricain	-	
3.4.22.31	Ananain	-	
3.4.22.32	Stem bromelain	-	
3.4.22.33	Fruit bromelain	-	
3.4.22.34	Legumain	-	
3.4.22.35	Histolysain	-	
3.4.22.36	caspase-1	-	
3.4.22.37	gingipain R	-	
3.4.22.38	cathepsin K	-	
3.4.22.39	adenain	-	
3.4.22.40	bleomycin hydrolase	-	
3.4.22.41	cathepsin F	-	
3.4.22.42	cathepsin O	-	
3.4.22.43	cathepsin V	-	
3.4.22.44	nuclear-inclusion-a endopeptidase	-	
3.4.22.45	helper-component proteinase	-	
3.4.22.46	L-peptidase	-	
3.4.22.47	gingipain K	-	
3.4.22.48	staphopain	-	
3.4.22.49	separase	-	
3.4.22.50	V-cath endopeptidase	-	
3.4.22.51	cruzipain	-	
3.4.22.52	calpain-1	-	
3.4.22.53	calpain-2	-	
3.4.22.54	calpain-3	-	
3.4.22.55	caspase-2	-	
3.4.22.56	caspase-3	-	
3.4.22.57	caspase-4	-	
3.4.22.58	caspase-5	-	
3.4.22.59	caspase-6	-	
3.4.22.60	caspase-7	-	
3.4.22.61	caspase-8	-	
3.4.22.62	caspase-9	-	
3.4.22.63	caspase-10	-	
3.4.22.64	caspase-11	-	
3.4.22.65	peptidase 1 (mite)	-	
3.4.22.66	calicivirin	-	
3.4.22.67	zingipain	-	
3.4.22.68	Ulp1 peptidase	-	
3.4.22.69	SARS coronavirus main proteinase	-	
3.4.22.70	sortase A	-	
3.4.22.71	sortase B	-	
3.4.22.13	staphylococcal cysteine proteinase	deleted	
3.4.22.20	dinorphin-converting enzyme	deleted	
3.4.22.B1	vignain	preliminary BRENDA-supplied EC number	
3.4.22.B5	CPB protease	preliminary BRENDA-supplied EC number	
3.4.22.B6	cathepsin B-like protease	preliminary BRENDA-supplied EC number	
3.4.22.B8	Tpr proteinase (Porphyromonas gingivalis)	preliminary BRENDA-supplied EC number	
3.4.22.B14	papain-like proteinase 1	preliminary BRENDA-supplied EC number	
3.4.22.B15	rabbit hemorrhagic disease virus 3C-like protease	preliminary BRENDA-supplied EC number	
3.4.22.B19	YopJ protease	preliminary BRENDA-supplied EC number	
3.4.22.B20	PfpI endopeptidase	preliminary BRENDA-supplied EC number	
3.4.22.B24	calpain 4	preliminary BRENDA-supplied EC number	
3.4.22.B25	calpain 5	preliminary BRENDA-supplied EC number	
3.4.22.B26	calpain 6	preliminary BRENDA-supplied EC number	
3.4.22.B27	calpain 7	preliminary BRENDA-supplied EC number	
3.4.22.B28	calpain 8	preliminary BRENDA-supplied EC number	
3.4.22.B29	calpain 9	preliminary BRENDA-supplied EC number	
3.4.22.B30	calpain 10	preliminary BRENDA-supplied EC number	
3.4.22.B31	calpain 11	preliminary BRENDA-supplied EC number	
3.4.22.B32	calpain 12	preliminary BRENDA-supplied EC number	
3.4.22.B35	calpain 15	preliminary BRENDA-supplied EC number	
3.4.22.B36	calpain A	preliminary BRENDA-supplied EC number	
3.4.22.B37	calpain B	preliminary BRENDA-supplied EC number	
3.4.22.B38	calpain C	preliminary BRENDA-supplied EC number	
3.4.22.B47	legume cysteine endopeptidase	preliminary BRENDA-supplied EC number	
3.4.22.B49	cathepsin L1	preliminary BRENDA-supplied EC number	
3.4.22.B50	papain-like proteinase 2	preliminary BRENDA-supplied EC number	
3.4.22.B60	cathepsin L2	preliminary BRENDA-supplied EC number	
3.4.22.B61	cathepsin L5	preliminary BRENDA-supplied EC number	
3.4.22.B62	cathepsin L3	preliminary BRENDA-supplied EC number	
3.4.22.B63	sortase C	preliminary BRENDA-supplied EC number	
3.4.22.B64	sortase D	preliminary BRENDA-supplied EC number	
3.4.22.B65	cathepsin P	preliminary BRENDA-supplied EC number	
3.4.22.B66	caspase-12	preliminary BRENDA-supplied EC number	
3.4.22.B67	Ulp2 peptidase	preliminary BRENDA-supplied EC number	
3.4.22.B68	EhCP4 proteinase	preliminary BRENDA-supplied EC number	
3.4.22.B69	falcipain-2	preliminary BRENDA-supplied EC number	
3.4.22.B70	SENP1 peptidase	preliminary BRENDA-supplied EC number	
3.4.22.B71	SENP2 peptidase	preliminary BRENDA-supplied EC number	
3.4.22.B72	SENP3 peptidase	preliminary BRENDA-supplied EC number	
3.4.22.B73	SENP5 peptidase	preliminary BRENDA-supplied EC number	
3.4.22.B74	SENP6 peptidase	preliminary BRENDA-supplied EC number	
3.4.22.B75	SENP7 peptidase	preliminary BRENDA-supplied EC number	
3.4.22.B76	Allium alpha-fibrinogenase AFTEII	preliminary BRENDA-supplied EC number	
3.4.22.B77	Sulfolobus solfataricus peptidase	preliminary BRENDA-supplied EC number	
3.4.22.B78	endopepidase PH1704	preliminary BRENDA-supplied EC number	
3.4.22.B79	nsP2 protease	preliminary BRENDA-supplied EC number	
3.4.22.B80	SARS-CoV papain-like protease	preliminary BRENDA-supplied EC number	
3.4.22.12	gamma-glutamyl hydrolase	transferred to EC 3.4.19.9	
3.4.22.18	prolyl endopeptidase (thiol-dependent)	transferred to EC 3.4.21.26	
3.4.22.9	yeast proteinase B	transferred to EC 3.4.21.48	
3.4.22.23	yeast cysteine proteinase F	transferred to EC 3.4.21.61	
3.4.22.4	bromelain (stem)	transferred to EC 3.4.22.32, EC  3.4.22.33	
3.4.22.5	bromelain (juice)	transferred to EC 3.4.22.33	
3.4.22.17	calpain	transferred to EC 3.4.22.52 and EC 3.4.22.53	
3.4.22.19	endo-oligopeptidase	transferred to EC 3.4.24.15	
3.4.22.22	yeast cysteine proteinase D	transferred to EC 3.4.24.37	
3.4.22.11	insulinase	transferred to EC 3.4.99.45	
3.4.22.21	yeast cysteine proteinase E	transferred to EC 3.4.99.46