2.7.11.16	Adenocarcinoma of Lung	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30984536&form=6&db=m	Hypermethylation of the G protein-coupled receptor kinase 6 (GRK6) promoter inhibits binding of C/EBP?, and GRK6 knockdown promotes cell migration and invasion in lung adenocarcinoma cells.	causal interaction,diagnostic usage,ongoing research,unassigned	4,3,2,0	
2.7.11.16	Alzheimer Disease	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18955119&form=6&db=m	Augmented axonal defects and synaptic degenerative changes in female GRK5 deficient mice.	causal interaction,unassigned	4,0	
2.7.11.16	Alzheimer Disease	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19478075&form=6&db=m	GRK5 deficiency leads to reduced hippocampal acetylcholine level via impaired presynaptic M2/M4 autoreceptor desensitization.	causal interaction,therapeutic application,unassigned	4,2,0	
2.7.11.16	Alzheimer Disease	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21041302&form=6&db=m	GRK5 deficiency accelerates {beta}-amyloid accumulation in Tg2576 mice via impaired cholinergic activity.	unassigned	-	
2.7.11.16	Alzheimer Disease	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24598771&form=6&db=m	GRK5 dysfunction accelerates tau hyperphosphorylation in APP (swe) mice through impaired cholinergic activity.	causal interaction,unassigned	4,0	
2.7.11.16	Aortic Coarctation	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28106155&form=6&db=m	Secreted miR-27a Induced by Cyclic Stretch Modulates the Proliferation of Endothelial Cells in Hypertension via GRK6.	causal interaction,unassigned	2,0	
2.7.11.16	Arthritis	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34006987&form=6&db=m	G protein-coupled receptor kinase 5 deletion suppresses synovial inflammation in a murine model of collagen antibody-induced arthritis.	unassigned	-	
2.7.11.16	Atrial Fibrillation	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25049040&form=6&db=m	G protein-coupled receptor kinase 5 gene polymorphisms are associated with postoperative atrial fibrillation after coronary artery bypass grafting in patients receiving ?-blockers.	causal interaction,diagnostic usage,therapeutic application,unassigned	3,1,2,0	
2.7.11.16	Breast Neoplasms	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18767025&form=6&db=m	Expression of G protein-coupled receptor kinase 4 is associated with breast cancer tumourigenesis.	causal interaction,diagnostic usage,ongoing research,unassigned	3,1,2,0	
2.7.11.16	Carcinogenesis	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18767025&form=6&db=m	Expression of G protein-coupled receptor kinase 4 is associated with breast cancer tumourigenesis.	causal interaction,diagnostic usage,ongoing research,unassigned	3,1,2,0