3.4.24.84	Acanthosis Nigricans	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20814950&form=6&db=m	Early onset mandibuloacral dysplasia due to compound heterozygous mutations in ZMPSTE24.	causal interaction,diagnostic usage,unassigned	4,2,0	
3.4.24.84	Acro-Osteolysis	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16278265&form=6&db=m	A homozygous mutation in the lamin A/C gene associated with a novel syndrome of arthropathy, tendinous calcinosis, and progeroid features.	causal interaction,unassigned	4,0	
3.4.24.84	Acro-Osteolysis	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20631028&form=6&db=m	A novel syndrome of mandibular hypoplasia, deafness, and progeroid features associated with lipodystrophy, undescended testes, and male hypogonadism.	causal interaction,unassigned	3,0	
3.4.24.84	Acro-Osteolysis	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20814950&form=6&db=m	Early onset mandibuloacral dysplasia due to compound heterozygous mutations in ZMPSTE24.	causal interaction,diagnostic usage,unassigned	4,2,0	
3.4.24.84	Acro-Osteolysis	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26602028&form=6&db=m	A novel homozygous LMNA mutation (p.Met540Ile) causes mandibuloacral dysplasia type A.	causal interaction,unassigned	3,0	
3.4.24.84	Alopecia	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18587406&form=6&db=m	Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging.	therapeutic application,unassigned	1,0	
3.4.24.84	Atherosclerosis	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26724531&form=6&db=m	LMNA mutations resulting in lipodystrophy and HIV protease inhibitors trigger vascular smooth muscle cell senescence and calcification: Role of ZMPSTE24 downregulation.	causal interaction,unassigned	4,0	
3.4.24.84	Carcinogenesis	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27729169&form=6&db=m	Mutational and expressional alterations of ZMPSTE24, DNA damage response-related gene, in gastric and colorectal cancers.	causal interaction,diagnostic usage,ongoing research,unassigned	2,3,4,0	
3.4.24.84	Carcinoma	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10373325&form=6&db=m	Identification and chromosomal location of two human genes encoding enzymes potentially involved in proteolytic maturation of farnesylated proteins.	ongoing research,unassigned	1,0	
3.4.24.84	Cardiomyopathies	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27120622&form=6&db=m	A Heterozygous ZMPSTE24 Mutation Associated with Severe Metabolic Syndrome, Ectopic Fat Accumulation, and Dilated Cardiomyopathy.	causal interaction,ongoing research,therapeutic application,unassigned	4,1,1,0