3.4.17.23 Down Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9325052&form=6&db=m Cloning of the TMPRSS2 gene, which encodes a novel serine protease with transmembrane, LDLRA, and SRCR domains and maps to 21q22.3. unassigned - 3.4.17.23 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10485450&form=6&db=m Prostate-localized and androgen-regulated expression of the membrane-bound serine protease TMPRSS2. causal interaction,ongoing research,therapeutic application,unassigned 4,2,4,0 3.4.17.23 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10485450&form=6&db=m Prostate-localized and androgen-regulated expression of the membrane-bound serine protease TMPRSS2. causal interaction,ongoing research,therapeutic application,unassigned 4,2,4,0 3.4.17.23 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11245484&form=6&db=m Catalytic cleavage of the androgen-regulated TMPRSS2 protease results in its secretion by prostate and prostate cancer epithelia. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,2,3 3.4.17.23 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11245484&form=6&db=m Catalytic cleavage of the androgen-regulated TMPRSS2 protease results in its secretion by prostate and prostate cancer epithelia. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,2,3 3.4.17.23 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11245484&form=6&db=m Catalytic cleavage of the androgen-regulated TMPRSS2 protease results in its secretion by prostate and prostate cancer epithelia. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,2,3 3.4.17.23 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11414763&form=6&db=m Mutation analyses of 268 candidate genes in human tumor cell lines. diagnostic usage,ongoing research,unassigned 1,4,0 3.4.17.23 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11414763&form=6&db=m Mutation analyses of 268 candidate genes in human tumor cell lines. diagnostic usage,ongoing research,unassigned 1,4,0 3.4.17.23 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11745466&form=6&db=m The TMPRSS2 gene encoding transmembrane serine protease is overexpressed in a majority of prostate cancer patients: detection of mutated TMPRSS2 form in a case of aggressive disease. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,2 3.4.17.23 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11745466&form=6&db=m The TMPRSS2 gene encoding transmembrane serine protease is overexpressed in a majority of prostate cancer patients: detection of mutated TMPRSS2 form in a case of aggressive disease. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,2