3.1.1.106 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25422431&form=6&db=m MACROD2 overexpression mediates estrogen independent growth and tamoxifen resistance in breast cancers. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,2,1 3.1.1.106 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29880585&form=6&db=m MACROD2 Haploinsufficiency Impairs Catalytic Activity of PARP1 and Promotes Chromosome Instability and Growth of Intestinal Tumors. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,4,1 3.1.1.106 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30619475&form=6&db=m Mono-ADP-Ribosylhydrolase MACROD2 Is Dispensable for Murine Responses to Metabolic and Genotoxic Insults. causal interaction,ongoing research,therapeutic application,unassigned 3,2,1,0 3.1.1.106 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31921812&form=6&db=m Copy Number Variation Pattern for Discriminating MACROD2 States of Colorectal Cancer Subtypes. causal interaction,diagnostic usage,therapeutic application,unassigned 2,3,1,0 3.1.1.106 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32151005&form=6&db=m The Controversial Roles of ADP-Ribosyl Hydrolases MACROD1, MACROD2 and TARG1 in Carcinogenesis. causal interaction,therapeutic application,unassigned 4,4,0 3.1.1.106 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32257385&form=6&db=m MACROD2 deficiency promotes hepatocellular carcinoma growth and metastasis by activating GSK-3?/?-catenin signaling. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,1,0 3.1.1.106 Colonic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30034629&form=6&db=m MACROD2 expression predicts response to 5-FU-based chemotherapy in stage III colon cancer. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,4,4,3 3.1.1.106 Colorectal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29880585&form=6&db=m MACROD2 Haploinsufficiency Impairs Catalytic Activity of PARP1 and Promotes Chromosome Instability and Growth of Intestinal Tumors. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,4,1 3.1.1.106 Colorectal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30237848&form=6&db=m MACROD2 deletions cause impaired PARP1 activity and chromosome instability in colorectal cancer. causal interaction,diagnostic usage,unassigned 1,1,0 3.1.1.106 Colorectal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31921812&form=6&db=m Copy Number Variation Pattern for Discriminating MACROD2 States of Colorectal Cancer Subtypes. causal interaction,diagnostic usage,therapeutic application,unassigned 2,3,1,0