2.7.12.2	Achondroplasia	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25387261&form=6&db=m	C-type natriuretic Peptide plasma levels are elevated in subjects with achondroplasia, hypochondroplasia, and thanatophoric dysplasia.	causal interaction,unassigned	3,0	
2.7.12.2	Acidosis	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22685289&form=6&db=m	Acidosis Promotes Bcl-2 Family-mediated Evasion of Apoptosis: INVOLVEMENT OF ACID-SENSING G PROTEIN-COUPLED RECEPTOR GPR65 SIGNALING TO MEK/ERK.	therapeutic application,unassigned	1,0	
2.7.12.2	Acneiform Eruptions	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31604105&form=6&db=m	A retrospective chart review on oral retinoids as a treatment for epidermal growth factor receptor inhibitor- and mitogen-activated protein kinase kinase inhibitor-induced acneiform eruptions.	causal interaction,therapeutic application,unassigned	1,4,0	
2.7.12.2	Acute Kidney Injury	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15673293&form=6&db=m	MEK inhibitor, U0126, attenuates cisplatin-induced renal injury by decreasing inflammation and apoptosis.	causal interaction,ongoing research,unassigned	1,3,0	
2.7.12.2	Acute Lung Injury	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20562902&form=6&db=m	Protective effects of luteolin against lipopolysaccharide-induced acute lung injury involves inhibition of MEK/ERK and PI3K/Akt pathways in neutrophils.	ongoing research,therapeutic application,unassigned	2,3,0	
2.7.12.2	Acute Lung Injury	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34159337&form=6&db=m	Discovery of pan-ErbB inhibitors protecting from SARS-CoV-2 replication, inflammation, and lung injury by a drug repurposing screen.	causal interaction,ongoing research,therapeutic application,unassigned	2,1,2,0	
2.7.12.2	Adenocarcinoma	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10980611&form=6&db=m	Extracellular regulated kinase (ERK)-dependent regulation of sialomucin complex/rat Muc4 in mammary epithelial cells.	ongoing research,therapeutic application,unassigned	2,1,0	
2.7.12.2	Adenocarcinoma	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16492916&form=6&db=m	Claudin-4, mitogen-activated protein kinase kinase 4, and stratifin are markers of gastric adenocarcinoma precursor lesions.	diagnostic usage,ongoing research,unassigned	3,3,0	
2.7.12.2	Adenocarcinoma	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21989899&form=6&db=m	Expression of EGFR, HER2, Phosphorylated ERK and Phosphorylated MEK in Colonic Neoplasms of Familial Adenomatous Polyposis Patients.	causal interaction,diagnostic usage,ongoing research,unassigned	4,4,4,0	
2.7.12.2	Adenocarcinoma	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22135231&form=6&db=m	Coexistence of PIK3CA and other oncogene mutations in lung adenocarcinoma-rationale for comprehensive mutation profiling.	causal interaction,diagnostic usage,ongoing research,therapeutic application	4,3,2,3