7.2.2.3 Acidosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7025800&form=6&db=m Alterations in cell function with ischemia and shock and their correction. unassigned - 7.2.2.3 Acidosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8106360&form=6&db=m Enzymatic and functional evidence for adaptation of the vacuolar H(+)-ATPase in proximal tubule apical membranes from rats with chronic metabolic acidosis. causal interaction,ongoing research,unassigned 2,4,0 7.2.2.3 Acidosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9172686&form=6&db=m [Effect of acidosis on membrane potential and calcium transport in rat brain synaptosomes] diagnostic usage,ongoing research,unassigned 1,4,0 7.2.2.3 Acidosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9273365&form=6&db=m An immunocytochemical study of H+ ATPase in kidney transplant rejection. causal interaction,diagnostic usage,unassigned 1,3,0 7.2.2.3 Acidosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10352213&form=6&db=m Environmental distal renal tubular acidosis in Thailand: an enigma. diagnostic usage,unassigned 2,0 7.2.2.3 Acidosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15050724&form=6&db=m Lactic acidosis progressively impairs dopamine uptake in rat striatal synaptosomes by a mechanism partially independent of the Na+/K+-ATPase dysfunction. causal interaction,therapeutic application,unassigned 3,1,0 7.2.2.3 Acidosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15661104&form=6&db=m The acute effects of glycemic control on nerve conduction in human diabetics. causal interaction,diagnostic usage,unassigned 3,2,0 7.2.2.3 Acidosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16146060&form=6&db=m Magnesium role in cardiovascular diseases. ongoing research,unassigned 2,0 7.2.2.3 Acidosis, Lactic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15050724&form=6&db=m Lactic acidosis progressively impairs dopamine uptake in rat striatal synaptosomes by a mechanism partially independent of the Na+/K+-ATPase dysfunction. causal interaction,therapeutic application,unassigned 3,1,0 7.2.2.3 Acidosis, Renal Tubular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9273365&form=6&db=m An immunocytochemical study of H+ ATPase in kidney transplant rejection. causal interaction,diagnostic usage,unassigned 1,3,0 7.2.2.3 Acidosis, Renal Tubular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10352213&form=6&db=m Environmental distal renal tubular acidosis in Thailand: an enigma. diagnostic usage,unassigned 2,0 7.2.2.3 Acquired Immunodeficiency Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11642739&form=6&db=m Cytochemical localization of Na+/K+-ATPase activity in cochlear strial marginal cells after various catecholamine administrations. causal interaction,unassigned 4,0 7.2.2.3 Acromegaly http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1327650&form=6&db=m Basal metabolic rate in adults with growth hormone deficiency and in patients with acromegaly: relationship with lean body mass, plasma insulin level and leucocyte sodium pump activity. causal interaction,diagnostic usage,unassigned 4,3,0 7.2.2.3 Acromegaly http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2196126&form=6&db=m Increased activity of digoxin-like substance in low-renin hypertension in acromegaly. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,2,0 7.2.2.3 Acromegaly http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3027557&form=6&db=m Evidence of an endogenous digitalis-like factor in the plasma of patients with acromegaly. diagnostic usage,ongoing research,unassigned 1,4,0 7.2.2.3 Acromegaly http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3652481&form=6&db=m Leucocyte sodium transport in acromegaly. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,2,4,2 7.2.2.3 Acute Kidney Injury http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2074649&form=6&db=m Effects of acute and chronic uremia on active cation transport in rat myocardium. causal interaction,ongoing research,therapeutic application,unassigned 3,4,1,0 7.2.2.3 Acute Kidney Injury http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6291345&form=6&db=m The pathophysiology of septic shock: acute renal failure in rats following live E coli injection. A histochemical study of the proximal tubules. causal interaction,unassigned 1,0 7.2.2.3 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1690978&form=6&db=m Immunohistochemical localization of sodium-potassium-stimulated adenosine triphosphatase and carbonic anhydrase in human colon and colonic neoplasms. causal interaction,ongoing research,therapeutic application,unassigned 1,3,1,0 7.2.2.3 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=13770849&form=6&db=m Comparison of adenosine triphosphatase activity of nuclei and mitochondria from mouse mammary adenocarcinoma. ongoing research,unassigned 1,0 7.2.2.3 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18219996&form=6&db=m [Na+,K+ -ATPase activity characteristics in human colon adenocarcinoma] causal interaction,diagnostic usage,ongoing research,unassigned 4,3,3,0 7.2.2.3 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27682173&form=6&db=m Identification of Proteins Whose Interaction with Na+,K+-ATPase Is Triggered by Ouabain. diagnostic usage,ongoing research,therapeutic application,unassigned 1,3,1,0 7.2.2.3 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32731591&form=6&db=m Oxidative Stress and Apoptotic Responses Elicited by Nostoc-Synthesized Silver Nanoparticles against Different Cancer Cell Lines. ongoing research,therapeutic application,unassigned 4,1,0 7.2.2.3 Adenocarcinoma of Lung http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20719125&form=6&db=m [Expression of Copper-Transporting P-Type Adenosine Triphosphatase (ATP7B) Correlates with Cisplatin-Resistance in Human Lung Adenocarcinoma Cell Line A549.] ongoing research,therapeutic application,unassigned 3,1,0 7.2.2.3 Adenocarcinoma, Papillary http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2436780&form=6&db=m Immunohistochemical and histochemical markers of primary lung cancer, lung metastases, and pleural mesotheliomas. diagnostic usage,ongoing research,therapeutic application,unassigned 3,2,1,0 7.2.2.3 Adenoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1690978&form=6&db=m Immunohistochemical localization of sodium-potassium-stimulated adenosine triphosphatase and carbonic anhydrase in human colon and colonic neoplasms. causal interaction,ongoing research,therapeutic application,unassigned 1,3,1,0 7.2.2.3 Adenoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4226159&form=6&db=m [Enzymatic activity of adenosine triphosphatase and acid phosphatase in adenoma of the tongue] diagnostic usage,unassigned 1,0 7.2.2.3 Adenoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24399884&form=6&db=m Gene mutations that promote adrenal aldosterone production, sodium retention, and hypertension. unassigned - 7.2.2.3 Adenoma, Oxyphilic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2138585&form=6&db=m Mitochondrial adenosine triphosphatase in the oxyphil cells of a renal oncocytoma. ongoing research,unassigned 2,0 7.2.2.3 Adenoma, Pleomorphic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6148924&form=6&db=m A cytochemical study on the salivary gland pleomorphic adenoma (mixed tumor) and the fetal and adult salivary gland. ongoing research,unassigned 4,0 7.2.2.3 Adrenal Insufficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3665131&form=6&db=m The human leucocyte sodium pump in adrenocortical insufficiency. causal interaction,diagnostic usage,unassigned 3,1,0 7.2.2.3 Albuminuria http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16267158&form=6&db=m Hyperaldosteronemia and activation of the epithelial sodium channel are not required for sodium retention in puromycin-induced nephrosis. causal interaction,unassigned 3,0 7.2.2.3 Alkalosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17512231&form=6&db=m Recovery from blood alkalosis in the Pacific hagfish (Eptatretus stoutii): involvement of gill V-H+-ATPase and Na+/K+-ATPase. unassigned - 7.2.2.3 Alkalosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18419554&form=6&db=m Is the alkaline tide a signal to activate metabolic or ionoregulatory enzymes in the dogfish shark (Squalus acanthias)? unassigned - 7.2.2.3 Altitude Sickness http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3025901&form=6&db=m Transport ATPases in the erythrocytes of rats acclimatized to intermittent altitude hypoxia. causal interaction,ongoing research,unassigned 2,2,0 7.2.2.3 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6251175&form=6&db=m Specificity of biophysical and biochemical alterations in erythrocyte membranes in neurological disorders--Huntington's disease, Friedreich's ataxia, Alzheimer's disease, amyotrophic lateral sclerosis, and myotonic and duchenne muscular dystrophy. diagnostic usage,therapeutic application,unassigned 3,1,0 7.2.2.3 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12417319&form=6&db=m Regulation of the frontocortical sodium pump by Na+ in Alzheimer's disease: difference from the age-matched control but similarity to the rat model. ongoing research,unassigned 4,0 7.2.2.3 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12467886&form=6&db=m Phosphatidylinositol and PI-4-monophosphate recover amyloid beta protein-induced inhibition of Cl- -ATPase activity. ongoing research,unassigned 1,0 7.2.2.3 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23830383&form=6&db=m Genetic variability in copper-transporting P-type adenosine triphosphatase (ATP7B) is associated with Alzheimer's disease in a Chinese population. causal interaction,unassigned 4,0 7.2.2.3 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30827871&form=6&db=m Alzheimer A? Assemblies Accumulate in Excitatory Neurons upon Proteasome Inhibition and Kill Nearby NAK?3 Neurons by Secretion. causal interaction,unassigned 1,0 7.2.2.3 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33651275&form=6&db=m Effect of a purine derivative containing selenium to improve memory decline and anxiety through modulation of the cholinergic system and Na+/K+-ATPase in an Alzheimer's disease model. ongoing research,therapeutic application,unassigned 2,2,0 7.2.2.3 Amyotrophic Lateral Sclerosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6251175&form=6&db=m Specificity of biophysical and biochemical alterations in erythrocyte membranes in neurological disorders--Huntington's disease, Friedreich's ataxia, Alzheimer's disease, amyotrophic lateral sclerosis, and myotonic and duchenne muscular dystrophy. diagnostic usage,therapeutic application,unassigned 3,1,0 7.2.2.3 Amyotrophic Lateral Sclerosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28123025&form=6&db=m Sodium Pumps Mediate Activity-Dependent Changes in Mammalian Motor Networks. causal interaction,therapeutic application,unassigned 1,1,0 7.2.2.3 Anemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=125878&form=6&db=m [Some data on the activity of adenosine triphosphatase and acetylcholinesterase in the erythrocytes of patients with various forms of anemia] ongoing research,unassigned 3,0 7.2.2.3 Anemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4230205&form=6&db=m [Studies on renal anemias. 3. The behavior of the phosphoric esters of adenosine and adenosine triphosphatase of the erythrocytes in hyperazotemic states] ongoing research,unassigned 1,0 7.2.2.3 Anemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8905564&form=6&db=m Abnormalities in adenosine triphosphatase of the erythrocyte membrane in iron deficiency anaemia. causal interaction,unassigned 3,0 7.2.2.3 Anemia, Hemolytic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=154343&form=6&db=m Congenital non-spherocytic haemolytic anaemia variants with primary and secondary pyruvate kinase deficiency. II. Enzymatic studies. unassigned - 7.2.2.3 Anemia, Hemolytic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4222579&form=6&db=m [Adenosine triphosphatase activity in normal persons and patients with hemolytic anemia] diagnostic usage,ongoing research,unassigned 2,3,0 7.2.2.3 Anemia, Hemolytic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4257475&form=6&db=m [Adenosine triphosphatase (ATP-ase) deficiency in a family with nonspherocytic hemolytic anemia] unassigned - 7.2.2.3 Anemia, Hemolytic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14433154&form=6&db=m [Experimental hemolytic anemia induced by hetero-antisera. I. Behavior of the adenosine triphosphatase activity of erythrocytes.] ongoing research,therapeutic application,unassigned 2,1,0 7.2.2.3 Anemia, Hemolytic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16416207&form=6&db=m A new mutation of Wilson's disease P-type ATPase gene in a patient with cirrhosis and coombs-positive hemolytic anemia. unassigned - 7.2.2.3 Anemia, Iron-Deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8905564&form=6&db=m Abnormalities in adenosine triphosphatase of the erythrocyte membrane in iron deficiency anaemia. causal interaction,unassigned 3,0 7.2.2.3 Anemia, Pernicious http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1707813&form=6&db=m Monoclonal antibodies specific for the core protein of the beta-subunit of the gastric proton pump (H+/K+ ATPase). An autoantigen targetted in pernicious anaemia. causal interaction,ongoing research,unassigned 2,3,0 7.2.2.3 Anemia, Pernicious http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12198704&form=6&db=m Fas/CD95 is required for gastric mucosal damage in autoimmune gastritis. ongoing research,unassigned 4,0 7.2.2.3 Aneurysm http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29867740&form=6&db=m A Novel ATP1A2 Gene Variant Associated With Pure Sporadic Hemiplegic Migraine Improved After Patent Foramen Ovale Closure: A Case Report. causal interaction,unassigned 3,0 7.2.2.3 Apnea http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26102761&form=6&db=m 2B.03: URIC ACID LEVELS RELATED TO OBSTRUCTIVE SLEEP APNEA SYNDROME IN PATIENTS WITH HYPERTENSION FROM XINJIANG OF CHINA. unassigned - 7.2.2.3 Arrhythmias, Cardiac http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=139466&form=6&db=m Digitalis toxicity: lack of marked effect on brain na+,k+-adenosine triphosphatase in the cat. diagnostic usage,ongoing research,unassigned 3,3,0 7.2.2.3 Arrhythmias, Cardiac http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6308480&form=6&db=m Evidence against an involvement of Na+, K+-ATPase in antiarrhythmic mechanism of phenytoin. unassigned - 7.2.2.3 Arrhythmias, Cardiac http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17083072&form=6&db=m Beneficial effect of eplerenone on cardiac remodelling and electrical properties of the failing heart. therapeutic application,unassigned 2,0 7.2.2.3 Arrhythmias, Cardiac http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28493895&form=6&db=m The cardiac glycoside ouabain activates NLRP3 inflammasomes and promotes cardiac inflammation and dysfunction. causal interaction,therapeutic application,unassigned 4,4,0 7.2.2.3 Arrhythmias, Cardiac http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30579976&form=6&db=m Cardenolides: Insights from chemical structure and pharmacological utility. causal interaction,therapeutic application,unassigned 3,4,0 7.2.2.3 Arrhythmias, Cardiac http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31471016&form=6&db=m Exposure to low-level metalaxyl impacts the cardiac development and function of zebrafish embryos. diagnostic usage,unassigned 2,0 7.2.2.3 Arrhythmias, Cardiac http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32593664&form=6&db=m Angiotensin receptor-neprilysin inhibitior (thiorphan/irbesartan) decreased ischemia-reperfusion induced ventricular arrhythmias in rat; in vivo study. causal interaction,ongoing research,therapeutic application,unassigned 4,3,4,0 7.2.2.3 Arrhythmias, Cardiac http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34371141&form=6&db=m Investigation of cardiac glycosides from oleander in a human induced pluripotent stem cells derived cardiomyocyte model. causal interaction,unassigned 3,0 7.2.2.3 Arteriosclerosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14386906&form=6&db=m [Studies on arteriosclerosis and endangitis obliterans. VIII. Hexokinase and adenosine triphosphatase in skeletal muscles in peripheral vascular disorders.] diagnostic usage,ongoing research,therapeutic application,unassigned 3,2,1,0 7.2.2.3 Arteritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32964796&form=6&db=m Coronavirus interactions with the cellular autophagy machinery. ongoing research,unassigned 1,0 7.2.2.3 Arthritis, Rheumatoid http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2820052&form=6&db=m Decreased NA+, K+-ATPase activity in erythrocyte membrane from rheumatoid arthritis patients. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,2,0 7.2.2.3 Arthritis, Rheumatoid http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=13903318&form=6&db=m Adenosine triphosphatase activity in blood in rheumatoid arthritis. ongoing research,therapeutic application,unassigned 2,1,0 7.2.2.3 Arthrogryposis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30690204&form=6&db=m Biallelic loss of function variants in ATP1A2 cause hydrops fetalis, microcephaly, arthrogryposis and extensive cortical malformations. causal interaction,unassigned 1,0 7.2.2.3 Arthrogryposis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33880529&form=6&db=m ATP1A2- and ATP1A3-associated early profound epileptic encephalopathy and polymicrogyria. causal interaction,therapeutic application,unassigned 4,1,0 7.2.2.3 Asthma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=183309&form=6&db=m Leukocyte adenosine triphosphatase activity in human bronchial asthma. causal interaction,diagnostic usage,ongoing research,unassigned 1,4,4,0 7.2.2.3 Asthma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4240014&form=6&db=m [Increase of serum adenosine triphosphatase in bronchial asthma states] causal interaction,unassigned 3,0 7.2.2.3 Asthma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10545310&form=6&db=m Increased intracellular calcium and decreased activities of leucocyte Na+,K+-ATPase and Ca2+-ATPase in asthma. causal interaction,unassigned 2,0 7.2.2.3 Asthma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10639760&form=6&db=m Decreased sodium-potassium and calcium adenosine triphosphatase activity in asthma: modulation by inhaled and oral corticosteroids. causal interaction,therapeutic application,unassigned 3,1,0 7.2.2.3 Astrocytoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4254913&form=6&db=m Sodium-potassium adenosine triphosphatase activity in N-nitrosomethylurea-induced rat astrocytoma cells. ongoing research,unassigned 1,0 7.2.2.3 Ataxia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11453454&form=6&db=m High mitochondrial DNA T8993G mutation (<90%) without typical features of Leigh's and NARP syndromes. causal interaction,unassigned 3,0 7.2.2.3 Ataxia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15987881&form=6&db=m Mutation in the glutamate transporter EAAT1 causes episodic ataxia, hemiplegia, and seizures. ongoing research,therapeutic application,unassigned 3,1,0 7.2.2.3 Ataxia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16116111&form=6&db=m Mutation in the glutamate transporter EAAT1 causes episodic ataxia, hemiplegia, and seizures. ongoing research,therapeutic application,unassigned 3,1,0 7.2.2.3 Ataxia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16866717&form=6&db=m Migrainous vertigo: mutation analysis of the candidate genes CACNA1A, ATP1A2, SCN1A, and CACNB4. causal interaction,therapeutic application,unassigned 2,1,0 7.2.2.3 Ataxia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33578253&form=6&db=m A novel ATP1A2 variant associated with severe stepwise regression, hemiplegia, epilepsy and movement disorders in two unrelated patients. ongoing research,therapeutic application,unassigned 1,1,0 7.2.2.3 Atrial Fibrillation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10193721&form=6&db=m Down-regulation of L-type calcium channel and sarcoplasmic reticular Ca(2+)-ATPase mRNA in human atrial fibrillation without significant change in the mRNA of ryanodine receptor, calsequestrin and phospholamban: an insight into the mechanism of atrial electrical remodeling. ongoing research,unassigned 4,0 7.2.2.3 Atrial Fibrillation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30579976&form=6&db=m Cardenolides: Insights from chemical structure and pharmacological utility. causal interaction,therapeutic application,unassigned 3,4,0 7.2.2.3 Bacteremia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6291345&form=6&db=m The pathophysiology of septic shock: acute renal failure in rats following live E coli injection. A histochemical study of the proximal tubules. causal interaction,unassigned 1,0 7.2.2.3 Bartter Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6090182&form=6&db=m The effect of long-term treatment with spironolactone on sodium pump abnormalities in the red blood cells of patients with Bartter's syndrome. causal interaction,ongoing research,therapeutic application,unassigned 1,4,3,0 7.2.2.3 Bone Resorption http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14672894&form=6&db=m Metabolic activation stimulates acid secretion and expression of matrix degrading proteases in human osteoblasts. ongoing research,unassigned 3,0 7.2.2.3 Bone Resorption http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16805684&form=6&db=m Comparative analysis of the effects of a novel vacuolar adenosine 5'-triphosphatase inhibitor, FR202126, and doxycycline on bone loss caused by experimental periodontitis in rats. causal interaction,ongoing research,therapeutic application,unassigned 4,2,4,0 7.2.2.3 Bone Resorption http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30717974&form=6&db=m Proton pumping V-ATPase inhibitor bafilomycin A1 affects Rab7 lysosomal localization and abolishes anterograde trafficking of osteoclast secretory lysosomes. diagnostic usage,unassigned 3,0 7.2.2.3 Bradycardia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29750993&form=6&db=m Mutation of the Na+/K+-ATPase Atp1a1a.1 causes QT interval prolongation and bradycardia in zebrafish. causal interaction,ongoing research,unassigned 2,1,0 7.2.2.3 Bradycardia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32879254&form=6&db=m Mechanism in bradycardia induced by Trimethyltin chloride: Inhibition activity and expression of Na+/K+-ATPase and apoptosis in myocardia. causal interaction,ongoing research,unassigned 4,4,0 7.2.2.3 Brain Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2998145&form=6&db=m Na+/K+-ATPase activity and GABA uptake in astroglial cell-enriched fractions and synaptosomes derived from rats in the early stage of experimental hepatogenic encephalopathy. ongoing research,unassigned 2,0 7.2.2.3 Brain Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23761507&form=6&db=m Acute encephalopathy in familial hemiplegic migraine with ATP1A2 mutation. causal interaction,diagnostic usage,unassigned 4,1,0 7.2.2.3 Brain Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28445178&form=6&db=m Familial Hemiplegic Migraine With Asymmetric Encephalopathy Secondary to ATP1A2 Mutation: A Case Series. unassigned - 7.2.2.3 Brain Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31766058&form=6&db=m Early Treatment in Acute Severe Encephalopathy Caused by ATP1A2 Mutation of Familial Hemiplegic Migraine Type 2: Case Report and Literature Review. causal interaction,therapeutic application,unassigned 4,4,0 7.2.2.3 Brain Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33493807&form=6&db=m Early onset severe ATP1A2 epileptic encephalopathy: Clinical characteristics and underlying mutations. causal interaction,therapeutic application,unassigned 4,2,0 7.2.2.3 Brain Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33880529&form=6&db=m ATP1A2- and ATP1A3-associated early profound epileptic encephalopathy and polymicrogyria. causal interaction,therapeutic application,unassigned 4,1,0 7.2.2.3 Brain Edema http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=805337&form=6&db=m Neurologic manifestations of diabetic comas: correlation with biochemical alterations in the brain. causal interaction,unassigned 1,0 7.2.2.3 Brain Edema http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6319261&form=6&db=m Inhibition of rat brain Na+,K+-ATPase activity by serum from patients with fulminant hepatic failure. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,3,0 7.2.2.3 Brain Edema http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7976666&form=6&db=m The endogenous ouabain-like sodium pump inhibitor in cold injury-induced brain edema. therapeutic application,unassigned 1,0 7.2.2.3 Brain Edema http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11817620&form=6&db=m Effects of repeated brain ischemia induced by rapid lower body negative pressure on brain water and Na+,K+-ATPase activity in rats. ongoing research,unassigned 3,0 7.2.2.3 Brain Edema http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18817754&form=6&db=m Brain damage related to hemorrhagic transformation following cerebral ischemia and the role of K ATP channels. unassigned - 7.2.2.3 Brain Edema http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27959885&form=6&db=m Potassium Aspartate Attenuates Brain Injury Induced by Controlled Cortical Impact in Rats Through Increasing Adenosine Triphosphate (ATP) Levels, Na+/K+-ATPase Activity and Reducing Brain Edema. diagnostic usage,therapeutic application,unassigned 3,1,0 7.2.2.3 Brain Injuries http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18573545&form=6&db=m Na+,K+-ATPase activity impairment after experimental traumatic brain injury: relationship to spatial learning deficits and oxidative stress. ongoing research,therapeutic application,unassigned 4,1,0 7.2.2.3 Brain Injuries http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23459313&form=6&db=m Polymorphisms in migraine-associated gene, atp1a2, and ischemic stroke risk in a biracial population: the genetics of early onset stroke study. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,2,2,1 7.2.2.3 Brain Injuries http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23627131&form=6&db=m [Study on regulation of tanshinone II(A) on GFAP and ATPase and PDI of cerebral ischemia reperfusion injury in rats]. diagnostic usage,ongoing research,unassigned 1,2,0 7.2.2.3 Brain Injuries http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26722460&form=6&db=m Down-regulated Na(+)/K(+)-ATPase activity in ischemic penumbra after focal cerebral ischemia/reperfusion in rats. causal interaction,ongoing research,unassigned 2,1,0 7.2.2.3 Brain Injuries http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27959885&form=6&db=m Potassium Aspartate Attenuates Brain Injury Induced by Controlled Cortical Impact in Rats Through Increasing Adenosine Triphosphate (ATP) Levels, Na+/K+-ATPase Activity and Reducing Brain Edema. diagnostic usage,therapeutic application,unassigned 3,1,0 7.2.2.3 Brain Injuries, Traumatic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18573545&form=6&db=m Na+,K+-ATPase activity impairment after experimental traumatic brain injury: relationship to spatial learning deficits and oxidative stress. ongoing research,therapeutic application,unassigned 4,1,0 7.2.2.3 Brain Ischemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10959493&form=6&db=m Preconditioning prevents the inhibition of Na+,K+-ATPase activity after brain ischemia. causal interaction,therapeutic application,unassigned 1,3,0 7.2.2.3 Brain Ischemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11817620&form=6&db=m Effects of repeated brain ischemia induced by rapid lower body negative pressure on brain water and Na+,K+-ATPase activity in rats. ongoing research,unassigned 3,0 7.2.2.3 Brain Ischemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12502020&form=6&db=m The influence of MK-801 on the hippocampal free arachidonic acid level and Na+,K+-ATPase activity in global cerebral ischemia-exposed rats. diagnostic usage,ongoing research,therapeutic application,unassigned 3,3,1,0 7.2.2.3 Brain Ischemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21212860&form=6&db=m Combined actions of Na/K-ATPase, NCX1 and glutamate dependent NMDA receptors in ischemic rat brain penumbra. unassigned - 7.2.2.3 Brain Ischemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22266555&form=6&db=m Effect of deferoxamine on Na+K+ATPase activity after cerebral ischemia in rabbits. ongoing research,therapeutic application,unassigned 4,1,0 7.2.2.3 Brain Ischemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23627131&form=6&db=m [Study on regulation of tanshinone II(A) on GFAP and ATPase and PDI of cerebral ischemia reperfusion injury in rats]. diagnostic usage,ongoing research,unassigned 1,2,0 7.2.2.3 Brain Ischemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32126019&form=6&db=m Insights into the neuropathology of cerebral ischemia and its mechanisms. causal interaction,therapeutic application,unassigned 1,2,0 7.2.2.3 Brain Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19368079&form=6&db=m Present and potential future adjuvant issues in high-grade astrocytic glioma treatment. causal interaction,therapeutic application,unassigned 3,4,0 7.2.2.3 Brain Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33327966&form=6&db=m Spider venom components decrease glioblastoma cell migration and invasion through RhoA-ROCK and Na+/K+-ATPase ?2: potential molecular entities to treat invasive brain cancer. causal interaction,therapeutic application,unassigned 2,1,0 7.2.2.3 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11802810&form=6&db=m Copper-transporting P-type adenosine triphosphatase (ATP7B) is expressed in human breast carcinoma. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,2 7.2.2.3 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15602003&form=6&db=m Digitalis-induced signaling by Na+/K+-ATPase in human breast cancer cells. ongoing research,therapeutic application,unassigned 3,3,0 7.2.2.3 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16545799&form=6&db=m Pentoxifylline and its major oxidative metabolites exhibit different pharmacological properties. therapeutic application,unassigned 2,0 7.2.2.3 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17535733&form=6&db=m On the importance and mechanism of amplification of digitalis signal through Na+/K+-ATPase. causal interaction,therapeutic application,unassigned 1,2,0 7.2.2.3 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20664973&form=6&db=m Glyceraldehyde-3-phosphate dehydrogenase as a surface associated antigen on human breast cancer cell lines MACL-1 and MGSO-3. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,4,4 7.2.2.3 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26870246&form=6&db=m BRIP1 inhibits the tumorigenic properties of cervical cancer by regulating RhoA GTPase activity. causal interaction,therapeutic application,unassigned 3,1,0 7.2.2.3 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28529692&form=6&db=m Abnormal expression of ATP1A1 and ATP1A2 in breast cancer. ongoing research,unassigned 1,0 7.2.2.3 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28951049&form=6&db=m An easy and fast adenosine 5'-diphosphate quantification procedure based on hydrophilic interaction liquid chromatography-high resolution tandem mass spectrometry for determination of the in vitro adenosine 5'-triphosphatase activity of the human breast cancer resistance protein ABCG2. ongoing research,therapeutic application,unassigned 1,2,0 7.2.2.3 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28954515&form=6&db=m Inner Blood-Retinal Barrier Dominantly Expresses Breast Cancer Resistance Protein: Comparative Quantitative Targeted Absolute Proteomics Study of CNS Barriers in Pig. therapeutic application,unassigned 1,0 7.2.2.3 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29777796&form=6&db=m Identification of a sodium pump Na+/K+ ATPase ?1-targeted peptide for PET imaging of breast cancer. causal interaction,therapeutic application,unassigned 3,2,0 7.2.2.3 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31060669&form=6&db=m [A Simple Medical Research Microdevice for Analyzing Three-dimensional Migration of Tumor Cells in Vitro]. ongoing research,unassigned 3,0 7.2.2.3 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32731591&form=6&db=m Oxidative Stress and Apoptotic Responses Elicited by Nostoc-Synthesized Silver Nanoparticles against Different Cancer Cell Lines. ongoing research,therapeutic application,unassigned 4,1,0 7.2.2.3 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33762577&form=6&db=m Oleandrin, a cardiac glycoside, induces immunogenic cell death via the PERK/elF2?/ATF4/CHOP pathway in breast cancer. therapeutic application,unassigned 3,0 7.2.2.3 Bronchitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32964796&form=6&db=m Coronavirus interactions with the cellular autophagy machinery. ongoing research,unassigned 1,0 7.2.2.3 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26870246&form=6&db=m BRIP1 inhibits the tumorigenic properties of cervical cancer by regulating RhoA GTPase activity. causal interaction,therapeutic application,unassigned 3,1,0 7.2.2.3 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29653366&form=6&db=m Bufalin inhibits glioblastoma growth by promoting proteasomal degradation of the Na+/K+-ATPase ?1 subunit. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,1,4,1 7.2.2.3 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33122944&form=6&db=m ATP6AP2 is Overexpressed in Breast Cancer and Promotes Breast Cancer Progression. causal interaction,unassigned 3,0 7.2.2.3 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33868261&form=6&db=m Integrative Transcriptomic, Proteomic and Functional Analysis Reveals ATP1B3 as a Diagnostic and Potential Therapeutic Target in Hepatocellular Carcinoma. causal interaction,therapeutic application,unassigned 2,1,0 7.2.2.3 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=139308&form=6&db=m Enzymatic responses of transplanted tumour cells towards estrogen, progesterone and testosterone. ongoing research,unassigned 4,0 7.2.2.3 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=184914&form=6&db=m Distribution of adenosine triphosphatase in infiltrating ductal carcinoma and non-neoplastic breast. diagnostic usage,ongoing research,unassigned 3,4,0 7.2.2.3 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=923517&form=6&db=m Enzymatic responses of transplanted tumour cells towards estrogen, progesterone and testosterone. ongoing research,unassigned 4,0 7.2.2.3 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2285995&form=6&db=m Interaction of asterriquinone with deoxyribonucleic acid in vitro. unassigned - 7.2.2.3 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2558124&form=6&db=m Immunohistochemical localization of Na+, K+-ATPase in human normal and malignant pancreatic tissues. causal interaction,ongoing research,unassigned 2,4,0 7.2.2.3 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3010699&form=6&db=m Enzyme histochemistry and thyroid neoplasia. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,2,1 7.2.2.3 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4257636&form=6&db=m Elevated lymphocyte adenosine triphosphatase activity in patients with gastrointestinal carcinoma. causal interaction,diagnostic usage,unassigned 3,2,0 7.2.2.3 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6226554&form=6&db=m Changes of enzyme activities recognized in lymphocytes from patients with carcinoma of the gastrointestinal tract. causal interaction,diagnostic usage,ongoing research,unassigned 1,4,3,0 7.2.2.3 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9195978&form=6&db=m Novel progesterone target genes identified by an improved differential display technique suggest that progestin-induced growth inhibition of breast cancer cells coincides with enhancement of differentiation. unassigned - 7.2.2.3 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10211551&form=6&db=m Inhibition of Na+,K+-ATPase by cisplatin and its recovery by 2-mercaptoethanol in human squamous cell carcinoma cells. ongoing research,unassigned 4,0 7.2.2.3 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11605050&form=6&db=m Expression and cisplatin sensitivity of copper-transporting P-type adenosine triphosphatase (ATP7B) in human solid carcinoma cell lines. diagnostic usage,ongoing research,unassigned 1,4,0 7.2.2.3 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12216079&form=6&db=m Copper-transporting P-type adenosine triphosphatase (ATP7B) as a cisplatin based chemoresistance marker in ovarian carcinoma: comparative analysis with expression of MDR1, MRP1, MRP2, LRP and BCRP. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,3,4 7.2.2.3 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12445675&form=6&db=m Copper-transporting P-type adenosine triphosphatase (ATP7B) is expressed in human gastric carcinoma. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,4,1 7.2.2.3 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12509969&form=6&db=m Expression of copper-transporting P-type adenosine triphosphatase (ATP7B) as a chemoresistance marker in human oral squamous cell carcinoma treated with cisplatin. diagnostic usage,ongoing research,therapeutic application,unassigned 2,4,1,0 7.2.2.3 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12579336&form=6&db=m Expression of copper-transporting P-type adenosine triphosphatase in human esophageal carcinoma. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,1,4,4 7.2.2.3 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12820478&form=6&db=m Mutation analysis of copper-transporting P-type adenosine triphosphatase (ATP7B) in human solid carcinomas. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,2,4 7.2.2.3 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15972700&form=6&db=m A moving new role for the sodium pump in epithelial cells and carcinomas. causal interaction,diagnostic usage,ongoing research,unassigned 3,3,3,0 7.2.2.3 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16030471&form=6&db=m Expression of copper-transporting P-type adenosine triphosphatase (ATP7B) as a chemoresistance marker in human solid carcinomas. diagnostic usage,ongoing research,unassigned 3,3,0 7.2.2.3 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18636185&form=6&db=m Expression of copper-transporting P-type adenosine triphosphatase (ATP7B) correlates with cisplatin resistance in human non-small cell lung cancer xenografts. causal interaction,diagnostic usage,ongoing research,therapeutic application 2,1,3,3 7.2.2.3 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23221602&form=6&db=m Is ATP7B a predictive marker in patients with ovarian carcinoma treated with platinum-taxane combination chemotherapy? causal interaction,diagnostic usage,ongoing research,therapeutic application 3,4,4,2 7.2.2.3 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23412992&form=6&db=m Cardiotonic Steroids-Mediated Na+/K+-ATPase Targeting Could Circumvent Various Chemoresistance Pathways. causal interaction,diagnostic usage,therapeutic application,unassigned 4,3,1,0 7.2.2.3 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31934199&form=6&db=m Expression of ATP7A in esophageal squamous cell carcinoma (ESCC) and its clinical significance. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,4,0 7.2.2.3 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33411033&form=6&db=m Effects of SLC31A1 and ATP7B polymorphisms on platinum resistance in patients with esophageal squamous cell carcinoma receiving neoadjuvant chemoradiotherapy. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,2,4,1 7.2.2.3 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34201380&form=6&db=m Emergency Use of Targeted Osmotic Lysis for the Treatment of a Patient with Aggressive Late-Stage Squamous Cell Carcinoma of the Cervix. causal interaction,unassigned 2,0 7.2.2.3 Carcinoma in Situ http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25072283&form=6&db=m Polarization of the vacuolar adenosine triphosphatase delineates a transition to high-grade pancreatic intraepithelial neoplasm lesions. ongoing research,unassigned 4,0 7.2.2.3 Carcinoma, Ductal http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=184914&form=6&db=m Distribution of adenosine triphosphatase in infiltrating ductal carcinoma and non-neoplastic breast. diagnostic usage,ongoing research,unassigned 3,4,0 7.2.2.3 Carcinoma, Ehrlich Tumor http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=124205&form=6&db=m A Mg2+- and Ca2+-stimulated adenosine triphosphatase at the outer surface of Ehrlich ascites tumor cells. diagnostic usage,unassigned 3,0 7.2.2.3 Carcinoma, Ehrlich Tumor http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4404199&form=6&db=m Increase in adenosine triphosphatase activity of Ehrlich ascites tumor cells following serial cultivation in media with increased (hypertonic) NaCl content. unassigned - 7.2.2.3 Carcinoma, Ehrlich Tumor http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6100583&form=6&db=m Inhibition of tumor growth by an alkylation of the plasma membrane. unassigned - 7.2.2.3 Carcinoma, Ehrlich Tumor http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6211417&form=6&db=m Quercetin inhibition of the induction and function of cytotoxic T lymphocytes. ongoing research,unassigned 2,0 7.2.2.3 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=200859&form=6&db=m Mitochondrial ATPase of Zajdela hepatoma. II. Mitochondria of Zajdela hepatoma contain less adenosine triphosphatase than mitochondria of rat liver. diagnostic usage,ongoing research,unassigned 2,4,0 7.2.2.3 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=201877&form=6&db=m Mitochondrial adenosine triphosphatase of Zajdela hepatoma. III. Effect of uncouplers on the hydrolysis of intramitochondrial ATP. causal interaction,ongoing research,unassigned 1,1,0 7.2.2.3 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=213300&form=6&db=m Effects of db-cAMP and theophylline on cell surface adenosine triphosphatase activity in cultured hepatoma cells. ongoing research,unassigned 4,0 7.2.2.3 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4325001&form=6&db=m Deficiency of uncoupler-stimulated adenosine triphosphatase activity in tightly coupled hepatoma mitochondria. causal interaction,unassigned 2,0 7.2.2.3 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4364650&form=6&db=m Uncoupler-stimulated adenosine triphosphatase activity. Deficiency in intact mitochondria from Morris hepatomas and ascites tumor cells. unassigned - 7.2.2.3 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6237968&form=6&db=m Cytochemical studies of acid phosphatase, adenosine triphosphatase and lactic dehydrogenase activity in thioacetamide-induced hepatoma. ongoing research,unassigned 2,0 7.2.2.3 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15154620&form=6&db=m Expression of copper-transporting P-type adenosine triphosphatase (ATP7B) in human hepatocellular carcinoma. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,4 7.2.2.3 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19877184&form=6&db=m Adenosine triphosphatase pontin is overexpressed in hepatocellular carcinoma and coregulated with reptin through a new posttranslational mechanism. diagnostic usage,unassigned 1,0 7.2.2.3 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21181095&form=6&db=m Na+/K+-ATPase ?3 mediates sensitivity of hepatocellular carcinoma cells to bufalin. diagnostic usage,ongoing research,therapeutic application,unassigned 3,4,1,0 7.2.2.3 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26334094&form=6&db=m Na+/K+-ATPase ?1 subunit, a novel therapeutic target for hepatocellular carcinoma. causal interaction,therapeutic application,unassigned 1,4,0 7.2.2.3 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29946188&form=6&db=m Sodium orthovanadate overcomes sorafenib resistance of hepatocellular carcinoma cells by inhibiting Na+/K+-ATPase activity and hypoxia-inducible pathways. ongoing research,unassigned 2,0 7.2.2.3 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32349518&form=6&db=m Cinobufagin Triggers Defects in Spindle Formation and Cap-Dependent Translation in Liver Cancer Cells by Inhibiting the AURKA-mTOR-eIF4E Axis. causal interaction,diagnostic usage,unassigned 3,1,0 7.2.2.3 Carcinoma, Non-Small-Cell Lung http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7645956&form=6&db=m Role of sodium pump systems to determine sensitivity to mitomycin C in non-small cell lung cancer cell lines. ongoing research,therapeutic application,unassigned 4,1,0 7.2.2.3 Carcinoma, Non-Small-Cell Lung http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18636185&form=6&db=m Expression of copper-transporting P-type adenosine triphosphatase (ATP7B) correlates with cisplatin resistance in human non-small cell lung cancer xenografts. causal interaction,diagnostic usage,ongoing research,therapeutic application 2,1,3,3 7.2.2.3 Carcinoma, Non-Small-Cell Lung http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22304828&form=6&db=m Copper-transporting P-type adenosine triphosphatase (ATP7A) is associated with platinum-resistance in non-small cell lung cancer (NSCLC). causal interaction,diagnostic usage,unassigned 2,1,0 7.2.2.3 Carcinoma, Non-Small-Cell Lung http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24038379&form=6&db=m MiR-495 enhances the sensitivity of non-small cell lung cancer cells to platinum by modulation of copper-transporting P-type adenosine triphosphatase A (ATP7A). causal interaction,ongoing research,therapeutic application,unassigned 2,2,2,0 7.2.2.3 Carcinoma, Non-Small-Cell Lung http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26033426&form=6&db=m Clinical outcome of cisplatin-based chemotherapy is associated with the polymorphisms of GSTP1 and XRCC1 in advanced non-small cell lung cancer patients. causal interaction,diagnostic usage,therapeutic application,unassigned 4,4,3,0 7.2.2.3 Carcinoma, Non-Small-Cell Lung http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29970705&form=6&db=m Evaluation of the relationship of erythrocyte membrane Na+/K+-ATPase enzyme activity and tumor response to chemoradiotherapy in patients diagnosed with locally advanced nonsmall cell lung cancer and glioblastoma multiforme. diagnostic usage,ongoing research,therapeutic application,unassigned 4,1,1,0 7.2.2.3 Carcinoma, Renal Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23412992&form=6&db=m Cardiotonic Steroids-Mediated Na+/K+-ATPase Targeting Could Circumvent Various Chemoresistance Pathways. causal interaction,diagnostic usage,therapeutic application,unassigned 4,3,1,0 7.2.2.3 Carcinoma, Squamous Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10211551&form=6&db=m Inhibition of Na+,K+-ATPase by cisplatin and its recovery by 2-mercaptoethanol in human squamous cell carcinoma cells. ongoing research,unassigned 4,0 7.2.2.3 Carcinoma, Squamous Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18545997&form=6&db=m Cisplatin sensitivity of oral squamous carcinoma cells is regulated by Na+,K+-ATPase activity rather than copper-transporting P-type ATPases, ATP7A and ATP7B. unassigned - 7.2.2.3 Cardiomegaly http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=211764&form=6&db=m Studies on adenosine triphosphatase activity of rat cardiac myosin in isoproterenol-induced cardiac hypertrophy. ongoing research,therapeutic application,unassigned 1,2,0 7.2.2.3 Cardiomegaly http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2562064&form=6&db=m Changes in sarcolemmal adenosine triphosphatase activity and in ouabain sensitivity of rat myocardium in isoproterenol-induced cardiac hypertrophy. ongoing research,unassigned 2,0 7.2.2.3 Cardiomegaly http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3038578&form=6&db=m Pressure-induced cardiac hypertrophy: changes in Na+,K+-ATPase and glycoside actions in cats. unassigned - 7.2.2.3 Cardiomegaly http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9614140&form=6&db=m Multiple signal transduction pathways link Na+/K+-ATPase to growth-related genes in cardiac myocytes. The roles of Ras and mitogen-activated protein kinases. causal interaction,unassigned 3,0 7.2.2.3 Cardiomegaly http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10069680&form=6&db=m Angiotensin type 1 receptor antagonism with irbesartan inhibits ventricular hypertrophy and improves diastolic function in the remodeling post-myocardial infarction ventricle. diagnostic usage,unassigned 1,0 7.2.2.3 Cardiomegaly http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12732449&form=6&db=m Regulation of sarco(endo)plasmic reticulum Ca2+ adenosine triphosphatase by phospholamban and sarcolipin: implication for cardiac hypertrophy and failure. causal interaction,ongoing research,therapeutic application,unassigned 4,2,1,0 7.2.2.3 Cardiomegaly http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17451677&form=6&db=m Na+/K+-ATPase alpha isoforms expression in stroke-prone spontaneously hypertensive rat heart ventricles: effect of salt loading and lacidipine treatment. causal interaction,unassigned 3,0 7.2.2.3 Cardiomegaly http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17612654&form=6&db=m Ral-GTPase interacts with the beta1 subunit of Na+/K+-ATPase and is activated upon inhibition of the Na+/K+ pump. causal interaction,unassigned 1,0 7.2.2.3 Cardiomyopathies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2074649&form=6&db=m Effects of acute and chronic uremia on active cation transport in rat myocardium. causal interaction,ongoing research,therapeutic application,unassigned 3,4,1,0 7.2.2.3 Cardiomyopathies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2551352&form=6&db=m Sodium pump and calcium channel modulation of Mg-deficiency cardiomyopathy. causal interaction,unassigned 2,0 7.2.2.3 Cardiomyopathies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11875585&form=6&db=m Effects of chronic, rapid right atrial pacing on cardiac hemodynamics and myofibrillar ATPase activity in piglets. unassigned - 7.2.2.3 Cardiomyopathies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16368801&form=6&db=m Cardiomyopathic etiology and SERCA2a reverse remodeling during mechanical support of the failing human heart. causal interaction,ongoing research,unassigned 1,1,0 7.2.2.3 Cardiomyopathies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16382260&form=6&db=m Sarcoplasmic reticulum adenosine triphosphatase overexpression in the L-type Ca2+ channel mouse results in cardiomyopathy and Ca2+ -induced arrhythmogenesis. diagnostic usage,ongoing research,therapeutic application,unassigned 3,3,4,0 7.2.2.3 Cardiomyopathies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25037619&form=6&db=m Safety and efficacy of high-dose adeno-associated virus 9 encoding sarcoplasmic reticulum Ca(2+) adenosine triphosphatase delivered by molecular cardiac surgery with recirculating delivery in ovine ischemic cardiomyopathy. therapeutic application,unassigned 4,0 7.2.2.3 Cardiomyopathies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28338377&form=6&db=m Sodium potassium adenosine triphosphatase (Na/K-ATPase) as a therapeutic target for uremic cardiomyopathy. causal interaction,ongoing research,therapeutic application,unassigned 4,2,4,0 7.2.2.3 Cardiomyopathy, Dilated http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2582658&form=6&db=m Structure and function of contractile proteins in human dilated cardiomyopathy. unassigned - 7.2.2.3 Cardiomyopathy, Dilated http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2827453&form=6&db=m Human myocardial adenosine triphosphatase activities in health and heart failure. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,3,1 7.2.2.3 Cardiomyopathy, Hypertrophic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7645194&form=6&db=m Altered adenosine triphosphatase activities in pigs with naturally occurring hypertrophic cardiomyopathy. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,4,3,1 7.2.2.3 Cardiotoxicity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7438092&form=6&db=m Comparison of adriamycin- and ouabain-induced cytotoxicity and inhibition of 86rubidium transport in wild-type and ouabain-resistant C3H/10T1/2 mouse fibroblasts. ongoing research,unassigned 1,0 7.2.2.3 Cardiotoxicity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7508042&form=6&db=m Pharmacological characterization of the activity of endogenous inotropic factor from porcine left ventricle. therapeutic application,unassigned 1,0 7.2.2.3 Cardiotoxicity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22204337&form=6&db=m Cardiotonic Steroids-Mediated Targeting of the Na(+)/K(+)-ATPase to Combat Chemoresistant Cancers. causal interaction,unassigned 2,0 7.2.2.3 Cardiotoxicity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27941167&form=6&db=m Protective effects of dietary selenium and vitamin C in barium-induced cardiotoxicity. therapeutic application,unassigned 1,0 7.2.2.3 Cardiotoxicity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32758567&form=6&db=m Molecular mechanisms of bufadienolides and their novel strategies for cancer treatment. causal interaction,therapeutic application,unassigned 3,4,0 7.2.2.3 Cardiovascular Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2556921&form=6&db=m Recessive inheritance of a high number of sodium pump sites. ongoing research,unassigned 1,0 7.2.2.3 Cardiovascular Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23785175&form=6&db=m Effects of obesity and estradiol on Na+/K+-ATPase and their relevance to cardiovascular diseases. ongoing research,therapeutic application,unassigned 4,1,0 7.2.2.3 Cardiovascular Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28164755&form=6&db=m Regulation of Na+/K+-ATPase by Estradiol and IGF-1 in Cardio-Metabolic Diseases. causal interaction,diagnostic usage,therapeutic application,unassigned 3,3,4,0 7.2.2.3 Cardiovascular Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31783627&form=6&db=m Lanatoside C Induces G2/M Cell Cycle Arrest and Suppresses Cancer Cell Growth by Attenuating MAPK, Wnt, JAK-STAT, and PI3K/AKT/mTOR Signaling Pathways. causal interaction,therapeutic application,unassigned 1,4,0 7.2.2.3 Cataract http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=232607&form=6&db=m In vitro production of steroid cataract in bovine lens. Part II: measurement of sodium-potassium adenosine triphosphatase activity. ongoing research,therapeutic application,unassigned 1,1,0 7.2.2.3 Cataract http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2404857&form=6&db=m Lenticular rubidium uptake and plasma renin activity in weanling cataract-prone salt-sensitive rats. causal interaction,diagnostic usage,ongoing research,unassigned 1,1,3,0 7.2.2.3 Cataract http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2984622&form=6&db=m Studies on cataractogenesis in humans and in rats with alloxan-induced diabetes. I. Cation transport and sodium-potassium-dependent ATPase. unassigned - 7.2.2.3 Cataract http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6568980&form=6&db=m Oxidation and cataract. therapeutic application,unassigned 3,0 7.2.2.3 Cataract http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8457142&form=6&db=m Aldose reductase and its inhibition in the control of diabetic complications. causal interaction,therapeutic application,unassigned 4,4,0 7.2.2.3 Cataract http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9950600&form=6&db=m The effects of digitalis-like compounds on rat lenses. causal interaction,unassigned 1,0 7.2.2.3 Cataract http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10567200&form=6&db=m Sodium pump inhibition and regional expression of sodium pump alpha-isoforms in lens. causal interaction,unassigned 4,0 7.2.2.3 Cataract http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11805512&form=6&db=m Extracellular matrix and Na+,K+-ATPase in human corneas following cataract surgery: comparison with bullous keratopathy and Fuchs' dystrophy corneas. ongoing research,unassigned 3,0 7.2.2.3 Cataract http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24270425&form=6&db=m AKT activation promotes PTEN hamartoma tumor syndrome-associated cataract development. causal interaction,unassigned 4,0 7.2.2.3 Cataract http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33080303&form=6&db=m Topical nerve growth factor attenuates streptozotocin-induced diabetic cataracts via polyol pathway inhibition and Na+/K+-ATPase upregulation. causal interaction,diagnostic usage,unassigned 2,3,0 7.2.2.3 Cataract http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34097242&form=6&db=m Prevention of tubulin/aldose reductase association delays the development of pathological complications in diabetic rats. causal interaction,ongoing research,unassigned 3,4,0 7.2.2.3 Cerebellar Ataxia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27313535&form=6&db=m The Influence of Na(+), K(+)-ATPase on Glutamate Signaling in Neurodegenerative Diseases and Senescence. causal interaction,unassigned 1,0 7.2.2.3 Cerebellar Ataxia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29305691&form=6&db=m The CAPOS mutation in ATP1A3 alters Na/K-ATPase function and results in auditory neuropathy which has implications for management. causal interaction,unassigned 2,0 7.2.2.3 Cerebellar Ataxia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30409907&form=6&db=m Functional consequences of the CAPOS mutation E818K of Na+,K+-ATPase. unassigned - 7.2.2.3 Cerebellar Ataxia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30760526&form=6&db=m Asparagine-905 of the mammalian phospholipid flippase ATP8A2 is essential for lipid substrate-induced activation of ATP8A2 dephosphorylation. causal interaction,therapeutic application,unassigned 1,1,0 7.2.2.3 Cerebellar Ataxia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33880529&form=6&db=m ATP1A2- and ATP1A3-associated early profound epileptic encephalopathy and polymicrogyria. causal interaction,therapeutic application,unassigned 4,1,0 7.2.2.3 Cerebral Hemorrhage http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28185542&form=6&db=m Analysis of amplicon-based NGS data from neurological disease gene panels: a new method for allele drop-out management. diagnostic usage,ongoing research,therapeutic application,unassigned 1,1,1,0 7.2.2.3 Cerebral Infarction http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18817754&form=6&db=m Brain damage related to hemorrhagic transformation following cerebral ischemia and the role of K ATP channels. unassigned - 7.2.2.3 Chemical and Drug Induced Liver Injury http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8183594&form=6&db=m [Biochemical mechanisms of the effect of prostaglandin E2 on the effect of parenteral nitrogenous nutrition] unassigned - 7.2.2.3 Chemical and Drug Induced Liver Injury http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10402655&form=6&db=m [Effect of Arnica montana tincture on some hydrolytic enzyme activities of rat liver in experimental toxic hepatitis] ongoing research,unassigned 4,0 7.2.2.3 Cholecystitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2953084&form=6&db=m [Comparative characteristics of adenosine triphosphatase activity in the erythrocytes of patients with acute and chronic liver diseases, chronic cholecystitis and in HBs antigen carriers] causal interaction,diagnostic usage,ongoing research,unassigned 4,4,4,0 7.2.2.3 Cholera http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1337681&form=6&db=m Cholera toxin increases Na+/K+-ATPase activity in the RN22 Schwann cell line. ongoing research,unassigned 2,0 7.2.2.3 Cholera http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2605257&form=6&db=m The activation of rabbit intestinal adenylate cyclase by cholera toxin. ongoing research,unassigned 3,0 7.2.2.3 Cholera http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3782088&form=6&db=m Gangliosides modulate sodium transport in cultured toad kidney epithelia. diagnostic usage,ongoing research,therapeutic application,unassigned 3,1,2,0 7.2.2.3 Cholera http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4232310&form=6&db=m Sodium-potassium stimulated adenosine triphosphatase of the small intestine of man: studies in cholera and other diarrheal diseases. unassigned - 7.2.2.3 Cholera http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6027815&form=6&db=m Experimental cholera in the rabbit intestinal loop: fluid accumulation and sodium pump inhibition. ongoing research,therapeutic application,unassigned 1,1,0 7.2.2.3 Cholera http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9607407&form=6&db=m Angiotensin II AT1 receptor/signaling mechanisms in the biphasic effect of the peptide on proximal tubular Na+,K+-ATPase. ongoing research,therapeutic application,unassigned 3,2,0 7.2.2.3 Cholestasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6248686&form=6&db=m The respective roles of membrane cholesterol and of sodium potassium adenosine triphosphatase in the pathogenesis of lithocholate-induced cholestasis. unassigned - 7.2.2.3 Cholestasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6295906&form=6&db=m Modulation by S-adenosyl-L-methionine of hepatic Na+,K+-ATPase, membrane fluidity, and bile flow in rats with ethinyl estradiol-induced cholestasis. ongoing research,unassigned 1,0 7.2.2.3 Cholestasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9197346&form=6&db=m Significant increase of Kuppfer cells associated with loss of Na+,K+-ATPase activity in rat hepatic allograft rejection. causal interaction,unassigned 3,0 7.2.2.3 Cholestasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9500542&form=6&db=m A gene encoding a P-type ATPase mutated in two forms of hereditary cholestasis. therapeutic application,unassigned 1,0 7.2.2.3 Cholestasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10022591&form=6&db=m Intravenous fish oil emulsion attenuates total parenteral nutrition-induced cholestasis in newborn piglets. ongoing research,unassigned 1,0 7.2.2.3 Cholestasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17227448&form=6&db=m Effect of alpha-asarone and a derivative on lipids, bile flow and Na+/K+-ATPase in ethinyl estradiol-induced cholestasis in the rat. ongoing research,unassigned 2,0 7.2.2.3 Cholestasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28601073&form=6&db=m Role of Na+/K(+)-ATPase in Natriuretic Effect of Prolactin in a Model of Cholestasis of Pregnancy. ongoing research,unassigned 4,0 7.2.2.3 Cholestasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33437900&form=6&db=m Assessment of Adenosine Triphosphatase Phospholipid Transporting 8B1 (ATP8B1) Function in Patients With Cholestasis With ATP8B1 Deficiency by Using Peripheral Blood Monocyte-Derived Macrophages. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,2,2,1 7.2.2.3 Cholestasis, Intrahepatic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15341767&form=6&db=m Indel in the FIC1/ATP8B1 gene-a novel rare type of mutation associated with benign recurrent intrahepatic cholestasis. causal interaction,unassigned 3,0 7.2.2.3 Cholestasis, Intrahepatic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15919184&form=6&db=m The type 4 subfamily of P-type ATPases, putative aminophospholipid translocases with a role in human disease. causal interaction,unassigned 3,0 7.2.2.3 Cholestasis, Intrahepatic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24651716&form=6&db=m The Drosophila melanogaster Phospholipid Flippase dATP8B Is Required for Odorant Receptor Function. therapeutic application,unassigned 1,0 7.2.2.3 Cholestasis, Intrahepatic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25342496&form=6&db=m Autoimmune BSEP Disease: Disease Recurrence After Liver Transplantation for Progressive Familial Intrahepatic Cholestasis. causal interaction,unassigned 1,0 7.2.2.3 Cholestasis, Intrahepatic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33437900&form=6&db=m Assessment of Adenosine Triphosphatase Phospholipid Transporting 8B1 (ATP8B1) Function in Patients With Cholestasis With ATP8B1 Deficiency by Using Peripheral Blood Monocyte-Derived Macrophages. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,2,2,1 7.2.2.3 Cholestasis, Intrahepatic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34016879&form=6&db=m Mutation Analysis and Disease Features at Presentation in a Multi-Center Cohort of Children With Monogenic Cholestasis. unassigned - 7.2.2.3 Chondroma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6297258&form=6&db=m Enzyme histochemical study on bone tumors. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,1,2 7.2.2.3 Chondrosarcoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=151479&form=6&db=m Contribution to the knowledge of the fine structure of chondrosarcoma of bone. With a note on the localization of alkaline phosphatase and "ATPase". ongoing research,unassigned 2,0 7.2.2.3 Chondrosarcoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6297258&form=6&db=m Enzyme histochemical study on bone tumors. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,1,2 7.2.2.3 Chorea http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33578253&form=6&db=m A novel ATP1A2 variant associated with severe stepwise regression, hemiplegia, epilepsy and movement disorders in two unrelated patients. ongoing research,therapeutic application,unassigned 1,1,0 7.2.2.3 Colitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15676060&form=6&db=m Regional intestinal adaptations in Na+,K+-ATPase in experimental colitis and the contrasting effects of interferon-gamma. ongoing research,therapeutic application,unassigned 4,1,0 7.2.2.3 Colonic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1690978&form=6&db=m Immunohistochemical localization of sodium-potassium-stimulated adenosine triphosphatase and carbonic anhydrase in human colon and colonic neoplasms. causal interaction,ongoing research,therapeutic application,unassigned 1,3,1,0 7.2.2.3 Colonic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11355005&form=6&db=m Polyamines secreted by cancer cells possibly account for the impairment of the human erythrocyte sodium pump activity. diagnostic usage,ongoing research,unassigned 3,4,0 7.2.2.3 Colonic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22204337&form=6&db=m Cardiotonic Steroids-Mediated Targeting of the Na(+)/K(+)-ATPase to Combat Chemoresistant Cancers. causal interaction,unassigned 2,0 7.2.2.3 Colonic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23412992&form=6&db=m Cardiotonic Steroids-Mediated Na+/K+-ATPase Targeting Could Circumvent Various Chemoresistance Pathways. causal interaction,diagnostic usage,therapeutic application,unassigned 4,3,1,0 7.2.2.3 Colorectal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17409496&form=6&db=m Interaction of Mat-8 (FXYD-3) with Na+/K+-ATPase in colorectal cancer cells. therapeutic application,unassigned 1,0 7.2.2.3 Colorectal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34212047&form=6&db=m FXYD6 Regulates Chemosensitivity by Mediating the Expression of Na+/K+-ATPase ?1 and Affecting Cell Autophagy and Apoptosis in Colorectal Cancer. ongoing research,unassigned 1,0 7.2.2.3 Coma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6319261&form=6&db=m Inhibition of rat brain Na+,K+-ATPase activity by serum from patients with fulminant hepatic failure. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,3,0 7.2.2.3 Coma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27226003&form=6&db=m Recurrent coma and fever in familial hemiplegic migraine type 2. A prospective 15-year follow-up of a large family with a novel ATP1A2 mutation. ongoing research,unassigned 2,0 7.2.2.3 Coma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33684554&form=6&db=m Thermal acclimation alters Na+/K+-ATPase activity in a tissue-specific manner in Drosophila melanogaster. therapeutic application,unassigned 1,0 7.2.2.3 Confusion http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6091947&form=6&db=m Erythrocyte sodium pump activity in human obesity. ongoing research,unassigned 4,0 7.2.2.3 Confusion http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23761507&form=6&db=m Acute encephalopathy in familial hemiplegic migraine with ATP1A2 mutation. causal interaction,diagnostic usage,unassigned 4,1,0 7.2.2.3 Confusion http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31766058&form=6&db=m Early Treatment in Acute Severe Encephalopathy Caused by ATP1A2 Mutation of Familial Hemiplegic Migraine Type 2: Case Report and Literature Review. causal interaction,therapeutic application,unassigned 4,4,0 7.2.2.3 Contracture http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4253047&form=6&db=m Relationship between the potentiation of potassium-induced contracture of cardiac muscle by four cardenolides and their inhibitory effects on the sodium potassium activated adenosine triphosphatase of brain. ongoing research,therapeutic application,unassigned 2,1,0 7.2.2.3 Contracture http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6290640&form=6&db=m Enhancement of cardiac actions of ouabain and its binding to Na+, K+-adenosine triphosphatase by increased sodium influx in isolated guinea-pig heart. causal interaction,unassigned 2,0 7.2.2.3 Contracture http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7847532&form=6&db=m Role of the sodium-calcium exchange mechanism and the effect of magnesium on sodium-free and high-potassium contractures in pregnant human myometrium. ongoing research,unassigned 2,0 7.2.2.3 Contracture http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16100049&form=6&db=m Calpain-mediated impairment of Na+/K+-ATPase activity during early reperfusion contributes to cell death after myocardial ischemia. causal interaction,ongoing research,therapeutic application,unassigned 2,2,1,0 7.2.2.3 Corneal Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12796256&form=6&db=m Human corneal endothelial cell expression of Na+,K+-adenosine triphosphatase isoforms. causal interaction,unassigned 3,0 7.2.2.3 Corneal Edema http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12796256&form=6&db=m Human corneal endothelial cell expression of Na+,K+-adenosine triphosphatase isoforms. causal interaction,unassigned 3,0 7.2.2.3 Coronary Artery Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25426658&form=6&db=m Increased membrane lipid peroxidation and decreased Na+/K+-ATPase activity in erythrocytes of patients with stable coronary artery disease. diagnostic usage,ongoing research,unassigned 4,2,0 7.2.2.3 Coronary Artery Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30731468&form=6&db=m Decreased Na+/K+-ATPase Activity and Altered Susceptibility to Peroxidation and Lipid Composition in the Erythrocytes of Metabolic Syndrome Patients with Coronary Artery Disease. diagnostic usage,ongoing research,unassigned 1,2,0 7.2.2.3 Coronavirus Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32964796&form=6&db=m Coronavirus interactions with the cellular autophagy machinery. ongoing research,unassigned 1,0 7.2.2.3 Cough http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19864578&form=6&db=m Selective expression of a sodium pump isozyme by cough receptors and evidence for its essential role in regulating cough. causal interaction,therapeutic application,unassigned 1,1,0 7.2.2.3 Cough http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26048736&form=6&db=m Regulation of cough by neuronal Na(+)-K(+) ATPases. therapeutic application,unassigned 1,0 7.2.2.3 COVID-19 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32964796&form=6&db=m Coronavirus interactions with the cellular autophagy machinery. ongoing research,unassigned 1,0 7.2.2.3 COVID-19 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33254543&form=6&db=m Hypotheses about sub-optimal hydration in the weeks before coronavirus disease (COVID-19) as a risk factor for dying from COVID-19. causal interaction,unassigned 3,0 7.2.2.3 COVID-19 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33935717&form=6&db=m Na+/K+-ATPase as a Target of Cardiac Glycosides for the Treatment of SARS-CoV-2 Infection. causal interaction,therapeutic application,unassigned 3,4,0 7.2.2.3 Craniocerebral Trauma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1652353&form=6&db=m The prognostic value of the brain sodium-potassium ATPase enzyme concentration in head injury. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,3,0 7.2.2.3 Craniocerebral Trauma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16437583&form=6&db=m Severe episodic neurological deficits and permanent mental retardation in a child with a novel FHM2 ATP1A2 mutation. causal interaction,therapeutic application,unassigned 4,1,0 7.2.2.3 Craniocerebral Trauma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32233732&form=6&db=m Exploring Neuronal Vulnerability to Head Trauma Using a Whole Exome Approach. causal interaction,therapeutic application,unassigned 4,1,0 7.2.2.3 Cushing Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2844449&form=6&db=m The human leucocyte sodium pump in Cushing's syndrome. ongoing research,unassigned 2,0 7.2.2.3 Cystic Fibrosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14610041&form=6&db=m Influence of salinity on the localization of Na+/K+-ATPase, Na+/K+/2Cl- cotransporter (NKCC) and CFTR anion channel in chloride cells of the Hawaiian goby (Stenogobius hawaiiensis). unassigned - 7.2.2.3 Cystic Fibrosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15914646&form=6&db=m Functional classification of mitochondrion-rich cells in euryhaline Mozambique tilapia (Oreochromis mossambicus) embryos, by means of triple immunofluorescence staining for Na+/K+-ATPase, Na+/K+/2Cl- cotransporter and CFTR anion channel. ongoing research,unassigned 2,0 7.2.2.3 Cystic Fibrosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16000541&form=6&db=m Gene expression after freshwater transfer in gills and opercular epithelia of killifish: insight into divergent mechanisms of ion transport. causal interaction,unassigned 2,0 7.2.2.3 Cystic Fibrosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16215213&form=6&db=m Chloride turnover and ion-transporting activities of yolk-sac preparations (yolk balls) separated from Mozambique tilapia embryos and incubated in freshwater and seawater. diagnostic usage,ongoing research,unassigned 2,2,0 7.2.2.3 Cystic Fibrosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17347004&form=6&db=m The effect of environmental salinity on the protein expression of Na+/K+-ATPase, Na+/K+/2Cl- cotransporter, cystic fibrosis transmembrane conductance regulator, anion exchanger 1, and chloride channel 3 in gills of a euryhaline teleost, Tetraodon nigroviridis. unassigned - 7.2.2.3 Cystic Fibrosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29547542&form=6&db=m Transepithelial Fluid and Salt Re-Absorption Regulated by cGK2 Signals. unassigned - 7.2.2.3 Cystic Fibrosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30315867&form=6&db=m The effects of transfer from steady-state to tidally-changing salinities on plasma and branchial osmoregulatory variables in adult Mozambique tilapia. ongoing research,unassigned 1,0 7.2.2.3 Cystic Fibrosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30334669&form=6&db=m Dynamics of Gene Expression Responses for Ion Transport Proteins and Aquaporins in the Gill of a Euryhaline Pupfish during Freshwater and High-Salinity Acclimation. unassigned - 7.2.2.3 Cystic Fibrosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30690150&form=6&db=m Short- and long-term low-salinity acclimation effects on the branchial and intestinal gene expression in the European seabass (Dicentrarchus labrax). unassigned - 7.2.2.3 Cystic Fibrosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31485757&form=6&db=m Systemic versus tissue-level prolactin signaling in a teleost during a tidal cycle. diagnostic usage,ongoing research,unassigned 1,2,0 7.2.2.3 Cystic Fibrosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32131732&form=6&db=m Genome-wide analysis of MicroRNA-messenger RNA interactome in ex-vivo gill filaments, Anguilla japonica. unassigned - 7.2.2.3 Cystic Fibrosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32364074&form=6&db=m Regulation of Cl- Electrolyte Permeability in Epithelia by Active Traditional Chinese Medicine Monomers for Diarrhea. unassigned - 7.2.2.3 Cystic Fibrosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32835784&form=6&db=m Cortisol regulates insulin-like growth-factor binding protein (igfbp) gene expression in Atlantic salmon parr. unassigned - 7.2.2.3 Cysts http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=126600&form=6&db=m [Ultrastructural localization of alkaline phosphatase and ATP-ase in cyst stages of Sarcocystis tenella (Sporozoa, Coccidia) parasitic in the esophagus of sheep (author's transl)] diagnostic usage,ongoing research,unassigned 3,1,0 7.2.2.3 Cysts http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1302436&form=6&db=m Effects of mebendazole, albendazole, and praziquantel on alkaline phosphatase, acid phosphatase, and adenosine triphosphatase of Echinococcus granulosus cysts harbored in mice. ongoing research,unassigned 3,0 7.2.2.3 Cysts http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2856368&form=6&db=m Congenital murine polycystic kidney disease. II. Pathogenesis of tubular cyst formation. causal interaction,diagnostic usage,ongoing research,unassigned 3,3,2,0 7.2.2.3 Cysts http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3029256&form=6&db=m Triiodothyronine-induced cyst formation in metanephric organ culture: the role of increased Na-K-adenosine triphosphatase activity. causal interaction,diagnostic usage,ongoing research,unassigned 4,1,4,0 7.2.2.3 Cysts http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6221499&form=6&db=m [Seasonal changes in the adenosine triphosphatase activity in the germinal cysts of the testis of the common frog Rana temporaria. An enzyme histochemical study] ongoing research,unassigned 2,0 7.2.2.3 Cysts http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7732635&form=6&db=m Sarcocystis fusiformis: some Krebs cycle enzymes in various fractions of sarcocysts of buffalo (Bubalus bubalis). diagnostic usage,unassigned 1,0 7.2.2.3 Cysts http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8575235&form=6&db=m Effect of antihydatid drugs on carbohydrate metabolism of metacestode of echinococcus granulosus. therapeutic application,unassigned 4,0 7.2.2.3 Cysts http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9142048&form=6&db=m A role for Na/K adenosine triphosphatase in the pathogenesis of cyst formation in experimental polycystic kidney disease. causal interaction,unassigned 4,0 7.2.2.3 Cytochrome-c Oxidase Deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10721666&form=6&db=m Mitochondrial DNA mutations in Leigh syndrome and their phylogenetic implications. causal interaction,causal interaction,diagnostic usage,diagnostic usage,therapeutic application,therapeutic application,unassigned,unassigned 4,4,3,3,1,1,0,0 7.2.2.3 Deficiency Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34430447&form=6&db=m Menkes disease diagnosed by a novel ATP7A frameshift mutation in a patient with infantile spasms-a case report. causal interaction,unassigned 4,0 7.2.2.3 Dehydration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9405828&form=6&db=m Solute effects on the sodium pump. An evaluation of the osmotic dehydration hypothesis. ongoing research,unassigned 2,0 7.2.2.3 Dehydration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14713515&form=6&db=m An hypothesis on the consolidation and PGE1-induced deconsolidation of a platelet plug. therapeutic application,unassigned 2,0 7.2.2.3 Dementia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16964263&form=6&db=m Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase. causal interaction,unassigned 3,0 7.2.2.3 Demyelinating Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22346256&form=6&db=m Potential implications of Helicobacter pylori-related neutrophil-activating protein. unassigned - 7.2.2.3 Demyelinating Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29914627&form=6&db=m Quercetin treatment regulates the Na+,K+-ATPase activity, peripheral cholinergic enzymes, and oxidative stress in a rat model of demyelination. causal interaction,ongoing research,therapeutic application,unassigned 1,4,2,0 7.2.2.3 Dengue http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29165589&form=6&db=m NS3 helicase from dengue virus specifically recognizes viral RNA sequence to ensure optimal replication. therapeutic application,unassigned 1,0 7.2.2.3 Dermatitis, Contact http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=686744&form=6&db=m Langerhans cells in contact dermatitis of the guinea pig. causal interaction,ongoing research,unassigned 1,2,0 7.2.2.3 Diabetes Complications http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2543581&form=6&db=m Modifications induced by diabetes on the physicochemical and functional properties of erythrocyte plasma membrane. causal interaction,unassigned 4,0 7.2.2.3 Diabetes Complications http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8457142&form=6&db=m Aldose reductase and its inhibition in the control of diabetic complications. causal interaction,therapeutic application,unassigned 4,4,0 7.2.2.3 Diabetes Complications http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25572761&form=6&db=m NO levels in diabetes mellitus: Effects of l-NAME and insulin on LCAT, Na(+)/K(+) ATPase activity and lipid profile. causal interaction,ongoing research,unassigned 1,3,0 7.2.2.3 Diabetes Mellitus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2170040&form=6&db=m [Tian-shou liquor on activity of cell membrane and energy metabolism in diabetes mellitus] ongoing research,unassigned 1,0 7.2.2.3 Diabetes Mellitus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3024950&form=6&db=m Sorbitol, myo-inositol and sodium-potassium ATPase in diabetic peripheral nerve. causal interaction,therapeutic application,unassigned 2,3,0 7.2.2.3 Diabetes Mellitus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10063931&form=6&db=m Small intestinal Na+,K+-adenosine triphosphatase activity and gene expression in experimental diabetes mellitus. diagnostic usage,ongoing research,unassigned 3,4,0 7.2.2.3 Diabetes Mellitus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10677386&form=6&db=m Effects of proinsulin C-peptide on nitric oxide, microvascular blood flow and erythrocyte Na+,K+-ATPase activity in diabetes mellitus type I. ongoing research,unassigned 4,0 7.2.2.3 Diabetes Mellitus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10727947&form=6&db=m Effect of streptozotocin-induced diabetes on rat liver Na+/K+-ATPase. diagnostic usage,therapeutic application,unassigned 1,2,0 7.2.2.3 Diabetes Mellitus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15748600&form=6&db=m Impairment of sodium pump and Na/H exchanger in erythrocytes from non-insulin dependent diabetes mellitus patients: effect of tea catechins. causal interaction,ongoing research,unassigned 1,2,0 7.2.2.3 Diabetes Mellitus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17942287&form=6&db=m Endogenous sodium pump inhibitors, diabetes mellitus and preeclampsia Preliminary observations and a hypothesis. causal interaction,therapeutic application,unassigned 4,4,0 7.2.2.3 Diabetes Mellitus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25572761&form=6&db=m NO levels in diabetes mellitus: Effects of l-NAME and insulin on LCAT, Na(+)/K(+) ATPase activity and lipid profile. causal interaction,ongoing research,unassigned 1,3,0 7.2.2.3 Diabetes Mellitus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34097242&form=6&db=m Prevention of tubulin/aldose reductase association delays the development of pathological complications in diabetic rats. causal interaction,ongoing research,unassigned 3,4,0 7.2.2.3 Diabetes Mellitus, Experimental http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2848052&form=6&db=m Abnormal membrane fluidity and acetylcholinesterase activity in erythrocytes from insulin-dependent diabetic patients. unassigned - 7.2.2.3 Diabetes Mellitus, Experimental http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2995180&form=6&db=m Reduced glomerular sodium/potassium adenosine triphosphatase activity in acute streptozocin diabetes and its prevention by oral sorbinil. causal interaction,therapeutic application,unassigned 4,3,0 7.2.2.3 Diabetes Mellitus, Experimental http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6126523&form=6&db=m Na+,K+-ATPase and Mg2+-ATPase activities in different regions of rat brain during alloxan diabetes. diagnostic usage,ongoing research,unassigned 2,4,0 7.2.2.3 Diabetes Mellitus, Experimental http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6309904&form=6&db=m Impaired rat sciatic nerve sodium-potassium adenosine triphosphatase in acute streptozocin diabetes and its correction by dietary myo-inositol supplementation. ongoing research,unassigned 3,0 7.2.2.3 Diabetes Mellitus, Experimental http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7047716&form=6&db=m Effects of streptozotocin diabetes and insulin treatment on myocardial sodium pump and contractility of the rat heart. ongoing research,therapeutic application,unassigned 2,4,0 7.2.2.3 Diabetes Mellitus, Type 1 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9005970&form=6&db=m Sialic acid, diabetes, and aging: a study on the erythrocyte membrane. causal interaction,diagnostic usage,ongoing research,unassigned 4,2,3,0 7.2.2.3 Diabetes Mellitus, Type 1 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9358075&form=6&db=m Modifications induced by insulin-dependent diabetes mellitus on human placental Na+/K+-adenosine triphosphatase. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,2,4,1 7.2.2.3 Diabetes Mellitus, Type 1 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10337852&form=6&db=m A study on human umbilical cord endothelial cells: functional modifications induced by plasma from insulin-dependent diabetes mellitus patients. ongoing research,unassigned 4,0 7.2.2.3 Diabetes Mellitus, Type 1 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10523028&form=6&db=m Influence of low density lipoprotein from insulin-dependent diabetic patients on platelet functions. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,1,4,1 7.2.2.3 Diabetes Mellitus, Type 1 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17289286&form=6&db=m Regulation of the inducible nitric oxide synthase and sodium pump in type 1 diabetes. causal interaction,ongoing research,therapeutic application,unassigned 3,3,1,0 7.2.2.3 Diabetes Mellitus, Type 2 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1313528&form=6&db=m Reduction of erythrocyte (Na(+)-K+) ATPase activities in non-insulin-dependent diabetic patients with hyperkalemia. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,3,0 7.2.2.3 Diabetes Mellitus, Type 2 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8929644&form=6&db=m Association of sick sinus syndrome with hyperinsulinemia and insulin resistance in patients with non-insulin-dependent diabetes mellitus: report of four cases. causal interaction,unassigned 3,0 7.2.2.3 Diabetes Mellitus, Type 2 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9005970&form=6&db=m Sialic acid, diabetes, and aging: a study on the erythrocyte membrane. causal interaction,diagnostic usage,ongoing research,unassigned 4,2,3,0 7.2.2.3 Diabetic Neuropathies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2539427&form=6&db=m Platelet sodium and potassium ATPase [corrected] activity and noradrenaline efflux rate in relation to autonomic and peripheral nerve function in insulin-dependent diabetic patients. diagnostic usage,ongoing research,therapeutic application,unassigned 4,3,1,0 7.2.2.3 Diabetic Neuropathies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6152683&form=6&db=m Endoneurial ATPase activity in Tangier disease and other peripheral neuropathies. causal interaction,diagnostic usage,ongoing research,unassigned 1,4,2,0 7.2.2.3 Diabetic Neuropathies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11887161&form=6&db=m Genetic and environmental regulation of Na/K adenosine triphosphatase activity in diabetic patients. causal interaction,unassigned 3,0 7.2.2.3 Diabetic Neuropathies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18036220&form=6&db=m Effect of pre-germinated brown rice intake on diabetic neuropathy in streptozotocin-induced diabetic rats. diagnostic usage,ongoing research,unassigned 1,3,0 7.2.2.3 Diabetic Neuropathies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22082324&form=6&db=m Metabolic correction in the management of diabetic peripheral neuropathy: improving clinical results beyond symptom control. causal interaction,unassigned 1,0 7.2.2.3 Diabetic Neuropathies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29864425&form=6&db=m Accumulation of sorbitol in the sciatic nerve modulates circadian properties of diabetes-induced neuropathic pain hypersensitivity in a diabetic mouse model. causal interaction,diagnostic usage,unassigned 2,3,0 7.2.2.3 Diabetic Neuropathies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30021390&form=6&db=m Erythropoietin: A potential drug in the management of diabetic neuropathy. causal interaction,unassigned 1,0 7.2.2.3 Down Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8384941&form=6&db=m Erythrocyte membrane cation carrier in Down syndrome. diagnostic usage,unassigned 2,0 7.2.2.3 Drug Resistant Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33578253&form=6&db=m A novel ATP1A2 variant associated with severe stepwise regression, hemiplegia, epilepsy and movement disorders in two unrelated patients. ongoing research,therapeutic application,unassigned 1,1,0 7.2.2.3 Duodenal Ulcer http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7770400&form=6&db=m [Prognostic factors of the speed of cicatrization in duodenal ulcer. Controlled trial of omeprazole versus ranitidine] therapeutic application,unassigned 4,0 7.2.2.3 Dystonia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16632466&form=6&db=m Mutations Phe785Leu and Thr618Met in Na+,K+-ATPase, associated with familial rapid-onset dystonia parkinsonism, interfere with Na+ interaction by distinct mechanisms. therapeutic application,unassigned 1,0 7.2.2.3 Dystonia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18957371&form=6&db=m The structure of the Na+,K+-ATPase and mapping of isoform differences and disease-related mutations. causal interaction,therapeutic application,unassigned 3,2,0 7.2.2.3 Dystonia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24904274&form=6&db=m Cellular function and pathological role of ATP13A2 and related P-type transport ATPases in Parkinson's disease and other neurological disorders. therapeutic application,unassigned 1,0 7.2.2.3 Dystonia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25164667&form=6&db=m Abnormal high-frequency burst firing of cerebellar neurons in rapid-onset dystonia-parkinsonism. therapeutic application,unassigned 2,0 7.2.2.3 Dystonia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25476251&form=6&db=m Genome-wide screen for modifiers of Na + /K + ATPase alleles identifies critical genetic loci. causal interaction,therapeutic application,unassigned 3,1,0 7.2.2.3 Dystonia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25713066&form=6&db=m Rescue of Na+ Affinity in Aspartate-928 Mutants of Na+,K+-ATPase by Secondary Mutation of Glutamate-314. unassigned - 7.2.2.3 Dystonia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28472154&form=6&db=m Hypothermia-induced dystonia and abnormal cerebellar activity in a mouse model with a single disease-mutation in the sodium-potassium pump. causal interaction,unassigned 1,0 7.2.2.3 Dystonia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33578253&form=6&db=m A novel ATP1A2 variant associated with severe stepwise regression, hemiplegia, epilepsy and movement disorders in two unrelated patients. ongoing research,therapeutic application,unassigned 1,1,0 7.2.2.3 Dystonic Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22422472&form=6&db=m Alternative Approaches to Modeling Hereditary Dystonias. unassigned - 7.2.2.3 Dystonic Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31712125&form=6&db=m Striatal dopaminergic dysregulation and dystonia-like movements induced by sensorimotor stress in a pharmacological mouse model of rapid-onset dystonia-parkinsonism. causal interaction,unassigned 3,0 7.2.2.3 Eczema http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=157633&form=6&db=m [Adenosine triphosphoric acid content and adenosine triphosphatase activity in eczema] ongoing research,unassigned 1,0 7.2.2.3 Embolism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9767164&form=6&db=m Microsphere embolism-induced changes in noradrenaline uptake of the cerebral cortex in rats. causal interaction,ongoing research,unassigned 1,2,0 7.2.2.3 Encephalitis, Tick-Borne http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9103040&form=6&db=m [Change in Na+,K+-ATPase activity during reproduction of the tick-borne encephalitis virus in SPEV cell culture] ongoing research,unassigned 3,0 7.2.2.3 Encephalomyelitis, Autoimmune, Experimental http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2957388&form=6&db=m Localization of adenosine triphosphatase activity of the endothelia in chronic relapsing experimental allergic encephalomyelitis. diagnostic usage,ongoing research,unassigned 2,4,0 7.2.2.3 Endolymphatic Hydrops http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11377885&form=6&db=m Na+,K+-ATPase and Ca2+-ATPase activities in the cochlear lateral wall following surgical induction of hydrops. causal interaction,ongoing research,unassigned 1,1,0 7.2.2.3 Endometrial Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15790435&form=6&db=m Expression of copper-transporting P-type adenosine triphosphatase (ATP7B) as a prognostic factor in human endometrial carcinoma. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,4 7.2.2.3 Eosinophilic Granuloma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6237717&form=6&db=m Langerhans' cells and macrophages in eosinophilic granuloma. An enzyme-histochemical, enzyme-cytochemical, and ultrastructural study. diagnostic usage,ongoing research,unassigned 2,2,0 7.2.2.3 Epilepsies, Partial http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1327744&form=6&db=m Contribution of Na+,K(+)-ATPase to focal epilepsy: a brief review. ongoing research,therapeutic application,unassigned 2,2,0 7.2.2.3 Epilepsies, Partial http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3004645&form=6&db=m Astroglial contribution in human temporal lobe epilepsy: K+ activation of Na+,K+-ATPase in bulk isolated glial cells and synaptosomes. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,2,4,2 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=125575&form=6&db=m Prophylactically administered phenytoin. Effects on the development of chronic cobalt-induced epilepsy in the cat. unassigned - 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2422895&form=6&db=m Na+,K+-ATPase: structure, function, and interactions with drugs. causal interaction,unassigned 2,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3004645&form=6&db=m Astroglial contribution in human temporal lobe epilepsy: K+ activation of Na+,K+-ATPase in bulk isolated glial cells and synaptosomes. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,2,4,2 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7607116&form=6&db=m Regional distributions of hippocampal Na+,K(+)-ATPase, cytochrome oxidase, and total protein in temporal lobe epilepsy. causal interaction,therapeutic application,unassigned 4,2,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12597054&form=6&db=m Mitochondrial disorders. unassigned - 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12598616&form=6&db=m Neural dysfunction and neurodegeneration in Drosophila Na+/K+ ATPase alpha subunit mutants. therapeutic application,unassigned 1,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14624354&form=6&db=m Update on the genetics of migraine. causal interaction,therapeutic application,unassigned 3,1,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15308625&form=6&db=m Kinetic alterations due to a missense mutation in the Na,K-ATPase alpha2 subunit cause familial hemiplegic migraine type 2. causal interaction,unassigned 4,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15970628&form=6&db=m Functional effects of Na+,K+-ATPase gene mutations. causal interaction,unassigned 3,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15985592&form=6&db=m Opening of the blood-brain barrier preceding cortical edema in a severe attack of FHM type II. causal interaction,unassigned 4,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16157018&form=6&db=m Analysis of chromosome 1 microsatellite markers and the FHM2-ATP1A2 gene mutations in migraine pedigrees. diagnostic usage,unassigned 2,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16508934&form=6&db=m The CACNA1A and ATP1A2 genes are not involved in dominantly inherited migraine with aura. unassigned - 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16508935&form=6&db=m Haplotype-based systematic association studies of ATP1A2 in migraine with aura. causal interaction,unassigned 3,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16915377&form=6&db=m [Genetics of migraine] causal interaction,unassigned 2,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18028407&form=6&db=m Epilepsy as part of the phenotype associated with ATP1A2 mutations. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,3,1 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18498390&form=6&db=m Severe attacks of familial hemiplegic migraine, childhood epilepsy and ATP1A2 mutation. causal interaction,ongoing research,unassigned 3,3,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20495966&form=6&db=m Migraine and epilepsy: A focus on overlapping clinical, pathophysiological, molecular, and therapeutic aspects. causal interaction,unassigned 4,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22013243&form=6&db=m Neurovascular changes in prolonged migraine aura in FHM with a novel ATP1A2 gene mutation. causal interaction,unassigned 2,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22483278&form=6&db=m The kinetics of non-synaptically triggered acute excitotoxic responses in the central nervous system observed using intrinsic optical signals. causal interaction,diagnostic usage,therapeutic application,unassigned 3,1,1,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22574873&form=6&db=m In vitro studies of the influence of glutamatergic agonists on the Na+,K+-ATPase and K+-p-nitrophenylphosphatase activities in the hippocampus and frontal cortex of rats. causal interaction,unassigned 3,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23561701&form=6&db=m Genetic effects of ATP1A2 in familial hemiplegic migraine type II and animal models. causal interaction,ongoing research,unassigned 4,4,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23838748&form=6&db=m Functional characterization of a novel C-terminal ATP1A2 mutation causing hemiplegic migraine and epilepsy. causal interaction,ongoing research,unassigned 2,2,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23918834&form=6&db=m A novel ATP1A2 gene mutation in familial hemiplegic migraine and epilepsy. causal interaction,ongoing research,unassigned 4,2,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23954377&form=6&db=m Familial hemiplegic migraine mutations affect Na,K-ATPase domain interactions. unassigned - 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24097848&form=6&db=m A Wide Clinical Phenotype Spectrum in Patients With ATP1A2 Mutations. causal interaction,ongoing research,unassigned 4,2,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25411546&form=6&db=m Biphasic neurovascular changes in prolonged migraine aura in familial hemiplegic migraine type 2. causal interaction,unassigned 2,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27052298&form=6&db=m Relationship between susceptibility to DMCM-induced generalized motor convulsions and low-affinity [3H]-ouabain binding in membranes in rat brain. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,1,1,1 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27127758&form=6&db=m Migraine in the era of precision medicine. ongoing research,unassigned 2,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28058944&form=6&db=m Epilepsy in hemiplegic migraine: Genetic mutations and clinical implications. causal interaction,diagnostic usage,ongoing research,unassigned 2,3,2,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28123025&form=6&db=m Sodium Pumps Mediate Activity-Dependent Changes in Mammalian Motor Networks. causal interaction,therapeutic application,unassigned 1,1,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28445178&form=6&db=m Familial Hemiplegic Migraine With Asymmetric Encephalopathy Secondary to ATP1A2 Mutation: A Case Series. unassigned - 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28479855&form=6&db=m The genetic relationship between epilepsy and hemiplegic migraine. unassigned - 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28527083&form=6&db=m Shared mechanisms of epilepsy, migraine and affective disorders. causal interaction,unassigned 4,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28811059&form=6&db=m An Infant With Epilepsy and Recurrent Hemiplegia due to Compound Heterozygous Variants in ATP1A2. causal interaction,unassigned 4,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29486580&form=6&db=m The contribution of CACNA1A, ATP1A2 and SCN1A mutations in hemiplegic migraine: A clinical and genetic study in Finnish migraine families. causal interaction,ongoing research,unassigned 4,2,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29867740&form=6&db=m A Novel ATP1A2 Gene Variant Associated With Pure Sporadic Hemiplegic Migraine Improved After Patent Foramen Ovale Closure: A Case Report. causal interaction,unassigned 3,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30167989&form=6&db=m New CACNA1A deletions are associated to migraine phenotypes. causal interaction,unassigned 3,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30185235&form=6&db=m Novel and de novo mutations in pediatric refractory epilepsy. causal interaction,unassigned 4,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32484063&form=6&db=m Characteristics of cortical spreading depression and c-Fos expression in transgenic mice having a mutation associated with familial hemiplegic migraine 2. causal interaction,unassigned 1,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33493807&form=6&db=m Early onset severe ATP1A2 epileptic encephalopathy: Clinical characteristics and underlying mutations. causal interaction,therapeutic application,unassigned 4,2,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33578253&form=6&db=m A novel ATP1A2 variant associated with severe stepwise regression, hemiplegia, epilepsy and movement disorders in two unrelated patients. ongoing research,therapeutic application,unassigned 1,1,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33839563&form=6&db=m Epilepsy in patients with familial hemiplegic migraine. causal interaction,ongoing research,unassigned 3,2,0 7.2.2.3 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34384358&form=6&db=m Functional correlation of ATP1A2 mutations with phenotypic spectrum: from pure hemiplegic migraine to its variant forms. causal interaction,unassigned 4,0 7.2.2.3 Epilepsy, Benign Neonatal http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12953268&form=6&db=m Novel mutations in the Na+, K+-ATPase pump gene ATP1A2 associated with familial hemiplegic migraine and benign familial infantile convulsions. causal interaction,unassigned 3,0 7.2.2.3 Epilepsy, Benign Neonatal http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15021241&form=6&db=m Genetics of the epilepsies. causal interaction,ongoing research,unassigned 3,1,0 7.2.2.3 Epilepsy, Generalized http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26003227&form=6&db=m Common variants of ATP1A3 but not ATP1A2 are associated with Chinese genetic generalized epilepsies. diagnostic usage,ongoing research,therapeutic application,unassigned 3,4,2,0 7.2.2.3 Epilepsy, Temporal Lobe http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3004645&form=6&db=m Astroglial contribution in human temporal lobe epilepsy: K+ activation of Na+,K+-ATPase in bulk isolated glial cells and synaptosomes. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,2,4,2 7.2.2.3 Epilepsy, Temporal Lobe http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7607116&form=6&db=m Regional distributions of hippocampal Na+,K(+)-ATPase, cytochrome oxidase, and total protein in temporal lobe epilepsy. causal interaction,therapeutic application,unassigned 4,2,0 7.2.2.3 Esophageal Squamous Cell Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31934199&form=6&db=m Expression of ATP7A in esophageal squamous cell carcinoma (ESCC) and its clinical significance. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,4,0 7.2.2.3 Esophageal Squamous Cell Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33411033&form=6&db=m Effects of SLC31A1 and ATP7B polymorphisms on platinum resistance in patients with esophageal squamous cell carcinoma receiving neoadjuvant chemoradiotherapy. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,2,4,1 7.2.2.3 Esophagitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14561010&form=6&db=m Regulation of Na/H exchanger-1 in gastroesophageal reflux disease: possible interaction of histamine receptor. causal interaction,diagnostic usage,ongoing research,unassigned 2,3,1,0 7.2.2.3 Esophagitis, Peptic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1553942&form=6&db=m Fulminant hepatic failure related to omeprazole. unassigned - 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1320078&form=6&db=m Platelet and erythrocyte Mg2+, Ca2+, Na+, K+ and cell membrane adenosine triphosphatase activity in essential hypertension in blacks. diagnostic usage,ongoing research,unassigned 1,4,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1321192&form=6&db=m Erythrocyte calcium-stimulated, magnesium-activated adenosine 5'-triphosphatase activity in essential hypertension. diagnostic usage,ongoing research,unassigned 2,2,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1336078&form=6&db=m Maximum binding of ouabain to erythrocytes in relation to a family history of essential hypertension, sodium balance and body weight in normotensive children. diagnostic usage,ongoing research,unassigned 2,2,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1395072&form=6&db=m Endogenous digitalis-like factors. causal interaction,unassigned 1,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1652190&form=6&db=m Erythrocyte membrane ouabain-sensitive Na+, K(+)-ATPase of hypertensive Nigerians. causal interaction,therapeutic application,unassigned 3,4,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1657500&form=6&db=m Low-concentration ouabain does not inhibit noradrenaline-induced contraction of human resistance arteries. causal interaction,therapeutic application,unassigned 3,4,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2165087&form=6&db=m Kinetics of the human leucocyte Na(+)-H+ antiport in essential hypertension. causal interaction,unassigned 3,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2165269&form=6&db=m Increased concentrations of a circulating sodium pump inhibitor in essential hypertension and uraemia and its partial purification from haemofiltrate. unassigned - 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2167808&form=6&db=m Effects of lead and a low-molecular-weight endogenous plasma inhibitor on the kinetics of sodium-potassium-activated adenosine triphosphatase and potassium-activated p-nitrophenylphosphatase. causal interaction,therapeutic application,unassigned 3,4,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2174283&form=6&db=m [(NA++K+)-ATPase inhibitor from bovine hypothalamus] causal interaction,therapeutic application,unassigned 1,1,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2439745&form=6&db=m Sodium pump inhibitor in the serum of patients with essential hypertension and its partial purification from hemofiltrate. causal interaction,diagnostic usage,unassigned 3,4,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2525203&form=6&db=m Relation of sodium-potassium adenosine triphosphatase inhibitor to sympathetic nervous system during salt-loading in essential hypertension. causal interaction,ongoing research,therapeutic application,unassigned 2,2,1,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2582182&form=6&db=m The sodium pump and energy regulation: some new aspects for essential hypertension, diabetes II and severe overweight. causal interaction,therapeutic application,unassigned 3,2,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2824366&form=6&db=m Ouabainlike Na+,K+-ATPase inhibitor in the plasma of normotensive and hypertensive humans and rats. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,1,2,3 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2824371&form=6&db=m Humoral sodium transport inhibitor in acute volume expansion and low renin hypertension. causal interaction,ongoing research,therapeutic application,unassigned 3,2,4,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2850642&form=6&db=m A plasma inhibitor of sodium and potassium activated adenosine triphosphatase in patients with essential hypertension. diagnostic usage,therapeutic application,unassigned 2,1,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2853728&form=6&db=m Relationship between the sympathetic nervous system and sodium potassium adenosine triphosphatase inhibitor in salt-sensitive patients with essential hypertension. causal interaction,diagnostic usage,ongoing research,unassigned 3,4,4,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2853743&form=6&db=m Partial purification and properties of a plasma ouabain-like inhibitor of Na+, K+-ATPase in patients with essential hypertension. causal interaction,diagnostic usage,ongoing research,unassigned 3,4,1,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2853744&form=6&db=m The effect of ouabain on pressor responses to infused noradrenaline in patients with essential hypertension. diagnostic usage,ongoing research,unassigned 4,3,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2987607&form=6&db=m Raised sodium pump activity and a circulating sodium transport inhibitor demonstrated on red blood cells of patients with untreated essential hypertension: correlation of pump activity with potassium permeability. diagnostic usage,ongoing research,therapeutic application,unassigned 4,3,2,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3009961&form=6&db=m Blood pressure in essential hypertension correlates with the concentration of a circulating inhibitor of the sodium pump. diagnostic usage,ongoing research,therapeutic application,unassigned 2,4,4,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3032788&form=6&db=m Red blood cell Na+,K+-ATPase in men with newly diagnosed or previously treated essential hypertension. causal interaction,ongoing research,therapeutic application,unassigned 3,4,3,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3034452&form=6&db=m Measurement by bioluminescence technique of erythrocyte membrane Na+,K+-ATPase activity in hypertensive patients. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,2,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3040304&form=6&db=m Assay of a circulating sodium pump inhibitor in patients with essential hypertension and normotensive subjects. causal interaction,diagnostic usage,therapeutic application,unassigned 3,2,1,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3040306&form=6&db=m Ouabain-like and non-ouabain-like factors in plasma of patients with essential hypertension. diagnostic usage,ongoing research,therapeutic application,unassigned 1,2,1,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3572458&form=6&db=m Genetic and ethnic influences on the distribution of sodium and potassium in normotensive and hypertensive subjects. diagnostic usage,ongoing research,unassigned 3,1,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3967468&form=6&db=m Effect of the calcium antagonist verapamil on human leucocyte sodium transport in vitro. unassigned - 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4017267&form=6&db=m Observations on the "cascade" of Na-K-ATPase inhibitory and digoxin-like immunoreactive material in human urine: possible relevance to essential hypertension. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,2,1 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6091295&form=6&db=m Reduced number of erythrocyte sodium pump units in essential hypertension. causal interaction,diagnostic usage,therapeutic application,unassigned 4,2,1,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6100615&form=6&db=m Plasma endogenous sodium pump inhibitor in essential hypertension. causal interaction,therapeutic application,unassigned 4,1,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6100752&form=6&db=m Effects of changes in dietary sodium intake on normotensive subjects with and without a genetic predisposition to essential hypertension. causal interaction,therapeutic application,unassigned 2,4,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6204159&form=6&db=m Plasma sodium pump inhibitor in essential hypertension and normotensive subjects with hypertensive heredity. causal interaction,therapeutic application,unassigned 4,3,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6204162&form=6&db=m Forearm vasoconstrictor response to ouabain: studies in patients with mild and moderate essential hypertension. diagnostic usage,ongoing research,unassigned 2,2,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6206353&form=6&db=m The role of a humoral Na+,K+-ATPase inhibitor in regulating precapillary vessel tone. causal interaction,therapeutic application,unassigned 4,4,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6274566&form=6&db=m An increase in a circulating inhibitor of Na+,K+-dependent ATPase: a possible link between salt intake and the development of essential hypertension. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,4,4,4 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6532603&form=6&db=m Abnormal leucocyte sodium transport in Chinese patients with essential hypertension and their normotensive offsprings. causal interaction,therapeutic application,unassigned 4,3,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6682639&form=6&db=m Role of a natriuretic factor in essential hypertension: an hypothesis. diagnostic usage,ongoing research,therapeutic application,unassigned 2,2,1,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7734097&form=6&db=m Digitalis-like factor and digoxin-like immunoreactive factor in diabetic women with preeclampsia, transient hypertension of pregnancy, and normotensive pregnancy. causal interaction,therapeutic application,unassigned 3,3,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7850405&form=6&db=m The sodium pump in hypertension. causal interaction,therapeutic application,unassigned 4,1,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8217031&form=6&db=m Predominance of high molecular weight plasma Na(+)-K(+)-ATPase inhibitor in essential hypertension. causal interaction,therapeutic application,unassigned 3,3,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9609049&form=6&db=m [Comparison of extra renal potassium management in hypertensive, diabetic and normal subjects] unassigned - 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10374376&form=6&db=m Erythrocyte and plasma Ca2+, Mg2+ and cell membrane adenosine triphosphatase activity in patients with essential hypertension. diagnostic usage,ongoing research,unassigned 4,4,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11276400&form=6&db=m Regulation of sodium/potassium ATPase activity: impact on salt balance and vascular contractility. causal interaction,unassigned 3,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19199261&form=6&db=m [Association of the polymorphisms of sodium transport related genes with essential hypertension] causal interaction,diagnostic usage,unassigned 4,1,0 7.2.2.3 Essential Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20959646&form=6&db=m Digibind Reverses Inhibition of Cellular rb+ Uptake Caused by Endogenous Sodium Pump Inhibitors Present in Serum and Placenta of Women With Preeclampsia. causal interaction,therapeutic application,unassigned 3,2,0 7.2.2.3 Facial Paralysis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8822727&form=6&db=m Impaired Ranvier node sodium-potassium adenosine triphosphatase may induce facial palsy. unassigned - 7.2.2.3 Fibroma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6297258&form=6&db=m Enzyme histochemical study on bone tumors. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,1,2 7.2.2.3 Foramen Ovale, Patent http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29867740&form=6&db=m A Novel ATP1A2 Gene Variant Associated With Pure Sporadic Hemiplegic Migraine Improved After Patent Foramen Ovale Closure: A Case Report. causal interaction,unassigned 3,0 7.2.2.3 Friedreich Ataxia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6251175&form=6&db=m Specificity of biophysical and biochemical alterations in erythrocyte membranes in neurological disorders--Huntington's disease, Friedreich's ataxia, Alzheimer's disease, amyotrophic lateral sclerosis, and myotonic and duchenne muscular dystrophy. diagnostic usage,therapeutic application,unassigned 3,1,0 7.2.2.3 Friedreich Ataxia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11579422&form=6&db=m Mitochondria and degenerative disorders. causal interaction,unassigned 3,0 7.2.2.3 galactokinase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15918549&form=6&db=m Suckling rat brain regional distribution of Na+,K+-atpase activity in the in vitro galactosaemia: the effect of L-cysteine and glutathione. diagnostic usage,ongoing research,unassigned 1,3,0 7.2.2.3 Galactosemias http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15918549&form=6&db=m Suckling rat brain regional distribution of Na+,K+-atpase activity in the in vitro galactosaemia: the effect of L-cysteine and glutathione. diagnostic usage,ongoing research,unassigned 1,3,0 7.2.2.3 Gallstones http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14972799&form=6&db=m Evidence for oxidative stress in the gall bladder mucosa of gall stone patients. causal interaction,diagnostic usage,ongoing research,unassigned 1,2,2,0 7.2.2.3 Gangliosidoses http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2983023&form=6&db=m Fluorescence polarization analysis, lipid composition, and Na+, K+-ATPase kinetics of synaptosomal membranes in feline GM1 and GM2 gangliosidosis. causal interaction,diagnostic usage,ongoing research,unassigned 1,3,2,0 7.2.2.3 Gangliosidosis, GM1 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2983023&form=6&db=m Fluorescence polarization analysis, lipid composition, and Na+, K+-ATPase kinetics of synaptosomal membranes in feline GM1 and GM2 gangliosidosis. causal interaction,diagnostic usage,ongoing research,unassigned 1,3,2,0 7.2.2.3 Gastritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1707813&form=6&db=m Monoclonal antibodies specific for the core protein of the beta-subunit of the gastric proton pump (H+/K+ ATPase). An autoantigen targetted in pernicious anaemia. causal interaction,ongoing research,unassigned 2,3,0 7.2.2.3 Gastritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8964405&form=6&db=m Analysis of mononuclear cell infiltrate and cytokine production in murine autoimmune gastritis. causal interaction,unassigned 3,0 7.2.2.3 Gastritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12198704&form=6&db=m Fas/CD95 is required for gastric mucosal damage in autoimmune gastritis. ongoing research,unassigned 4,0 7.2.2.3 Gastritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32376420&form=6&db=m Interleukin 27 Protects From Gastric Atrophy and Metaplasia During Chronic Autoimmune Gastritis. ongoing research,therapeutic application,unassigned 4,1,0 7.2.2.3 Gastritis, Atrophic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24187872&form=6&db=m Variations of energy metabolism and adenosine triphosphatase activity in gastric mucosa in chronic atrophic gastritis rats with Qi deficiency and blood stasis syndrome and effect of zhiweifangbian capsule. causal interaction,ongoing research,unassigned 2,3,0 7.2.2.3 Gastroenteritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30053394&form=6&db=m The cardenolide ouabain suppresses coronaviral replication via augmenting a Na+/K+-ATPase-dependent PI3K_PDK1 axis signaling. ongoing research,unassigned 1,0 7.2.2.3 Gastroenteritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32592721&form=6&db=m Natural cardenolides suppress coronaviral replication by downregulating JAK1 via a Na+/K+-ATPase independent proteolysise. unassigned - 7.2.2.3 Gastroesophageal Reflux http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11430507&form=6&db=m Improving on PPI-based therapy of GORD. therapeutic application,unassigned 3,0 7.2.2.3 Gastroesophageal Reflux http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14561010&form=6&db=m Regulation of Na/H exchanger-1 in gastroesophageal reflux disease: possible interaction of histamine receptor. causal interaction,diagnostic usage,ongoing research,unassigned 2,3,1,0 7.2.2.3 Genetic Diseases, Inborn http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29930807&form=6&db=m Mitochondrial G8292A and C8794T mutations in patients with Niemann-Pick disease type C. unassigned - 7.2.2.3 Giant Cell Tumors http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6297258&form=6&db=m Enzyme histochemical study on bone tumors. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,1,2 7.2.2.3 Glioblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18300910&form=6&db=m Targeting the alpha 1 subunit of the sodium pump to combat glioblastoma cells. ongoing research,unassigned 3,0 7.2.2.3 Glioblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18323016&form=6&db=m The sodium pump alpha1 subunit as a potential target to combat apoptosis-resistant glioblastomas. causal interaction,ongoing research,therapeutic application,unassigned 2,2,3,0 7.2.2.3 Glioblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18390407&form=6&db=m [The sodium pump could constitute a new target to combat glioblastomas] causal interaction,ongoing research,therapeutic application,unassigned 3,4,3,0 7.2.2.3 Glioblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19194651&form=6&db=m Editorial: on the road to multi-modal and pluri-disciplinary treatment of glioblastomas. causal interaction,diagnostic usage,therapeutic application,unassigned 4,3,4,0 7.2.2.3 Glioblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19368079&form=6&db=m Present and potential future adjuvant issues in high-grade astrocytic glioma treatment. causal interaction,therapeutic application,unassigned 3,4,0 7.2.2.3 Glioblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19995221&form=6&db=m Response of sodium pump to ouabain challenge in human glioblastoma cells in culture. diagnostic usage,ongoing research,unassigned 3,4,0 7.2.2.3 Glioblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22204337&form=6&db=m Cardiotonic Steroids-Mediated Targeting of the Na(+)/K(+)-ATPase to Combat Chemoresistant Cancers. causal interaction,unassigned 2,0 7.2.2.3 Glioblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25255962&form=6&db=m Inhibition of Na+/K+-ATPase induces hybrid cell death and enhanced sensitivity to chemotherapy in human glioblastoma cells. ongoing research,therapeutic application,unassigned 4,4,0 7.2.2.3 Glioblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26125228&form=6&db=m Epi-reevesioside F inhibits Na+/K+-ATPase, causing cytosolic acidification, Bak activation and apoptosis in glioblastoma. ongoing research,therapeutic application,unassigned 2,1,0 7.2.2.3 Glioblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29653366&form=6&db=m Bufalin inhibits glioblastoma growth by promoting proteasomal degradation of the Na+/K+-ATPase ?1 subunit. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,1,4,1 7.2.2.3 Glioblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29970705&form=6&db=m Evaluation of the relationship of erythrocyte membrane Na+/K+-ATPase enzyme activity and tumor response to chemoradiotherapy in patients diagnosed with locally advanced nonsmall cell lung cancer and glioblastoma multiforme. diagnostic usage,ongoing research,therapeutic application,unassigned 4,1,1,0 7.2.2.3 Glioblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30130132&form=6&db=m Update on the effects of the sodium pump ?1 subunit on human glioblastoma: from the laboratory to the clinic. causal interaction,ongoing research,therapeutic application,unassigned 3,4,4,0 7.2.2.3 Glioblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30739221&form=6&db=m The sodium pump ?1 subunit regulates bufalin sensitivity of human glioblastoma cells through the p53 signaling pathway. causal interaction,ongoing research,therapeutic application,unassigned 4,3,4,0 7.2.2.3 Glioblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31285960&form=6&db=m Targeting ?2 subunit of Na+/K+-ATPase induces glioblastoma cell apoptosis through elevation of intracellular Ca2. therapeutic application,unassigned 1,0 7.2.2.3 Glioblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33327966&form=6&db=m Spider venom components decrease glioblastoma cell migration and invasion through RhoA-ROCK and Na+/K+-ATPase ?2: potential molecular entities to treat invasive brain cancer. causal interaction,therapeutic application,unassigned 2,1,0 7.2.2.3 Glioma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4246202&form=6&db=m [Distribution of adenosine triphosphatase activity in the culture of cerebral gliomas] diagnostic usage,ongoing research,unassigned 3,2,0 7.2.2.3 Glioma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6289988&form=6&db=m Alterations of membrane integrity and cellular constituents by arachidonic acid in neuroblastoma and glioma cells. ongoing research,therapeutic application,unassigned 3,1,0 7.2.2.3 Glioma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17430305&form=6&db=m Lithium normalizes elevated intracellular sodium. causal interaction,ongoing research,therapeutic application,unassigned 3,3,3,0 7.2.2.3 Glioma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18323016&form=6&db=m The sodium pump alpha1 subunit as a potential target to combat apoptosis-resistant glioblastomas. causal interaction,ongoing research,therapeutic application,unassigned 2,2,3,0 7.2.2.3 Glioma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18390407&form=6&db=m [The sodium pump could constitute a new target to combat glioblastomas] causal interaction,ongoing research,therapeutic application,unassigned 3,4,3,0 7.2.2.3 Glioma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19368079&form=6&db=m Present and potential future adjuvant issues in high-grade astrocytic glioma treatment. causal interaction,therapeutic application,unassigned 3,4,0 7.2.2.3 Glioma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23412992&form=6&db=m Cardiotonic Steroids-Mediated Na+/K+-ATPase Targeting Could Circumvent Various Chemoresistance Pathways. causal interaction,diagnostic usage,therapeutic application,unassigned 4,3,1,0 7.2.2.3 Glioma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29582577&form=6&db=m Marinobufagenin inhibits glioma growth through sodium pump ?1 subunit and ERK signaling-mediated mitochondrial apoptotic pathway. ongoing research,unassigned 2,0 7.2.2.3 Glioma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30739221&form=6&db=m The sodium pump ?1 subunit regulates bufalin sensitivity of human glioblastoma cells through the p53 signaling pathway. causal interaction,ongoing research,therapeutic application,unassigned 4,3,4,0 7.2.2.3 Glioma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31114755&form=6&db=m ATP1A1 Integrates AKT and ERK Signaling via Potential Interaction With Src to Promote Growth and Survival in Glioma Stem Cells. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,4 7.2.2.3 Glomerulonephritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4252341&form=6&db=m [Adenosine triphosphatase activity of erythrocytes in diffuse glomerulonephritis in children] unassigned - 7.2.2.3 Glomerulonephritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10489230&form=6&db=m Glomerulonephritis and sodium retention: enhancement of Na+/K+-ATPase activity in the collecting duct is shared by rats with puromycin induced nephrotic syndrome and mice with spontaneous lupus-like glomerulonephritis. ongoing research,unassigned 3,0 7.2.2.3 glucose-6-phosphatase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2873887&form=6&db=m Induction of altered hepatic foci in rats by the administration of hypolipidemic peroxisome proliferators alone or following a single dose of diethylnitrosamine. unassigned - 7.2.2.3 Glycogen Storage Disease Type I http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2873887&form=6&db=m Induction of altered hepatic foci in rats by the administration of hypolipidemic peroxisome proliferators alone or following a single dose of diethylnitrosamine. unassigned - 7.2.2.3 Granuloma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=936426&form=6&db=m Susceptibility of desert sheep to infection with Schistosoma mansoni of Northern Sudan. ongoing research,unassigned 2,0 7.2.2.3 Graves Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3010699&form=6&db=m Enzyme histochemistry and thyroid neoplasia. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,2,1 7.2.2.3 Graves Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9863122&form=6&db=m [Therapeutic effect and its mechanism exploration on mainly using traditional Chinese medicine of replenishing qi and nourishing yin in treating Graves disease] therapeutic application,unassigned 3,0 7.2.2.3 Head and Neck Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7602937&form=6&db=m [The cytochemical determination of alpha-glycerophosphate dehydrogenase and adenosine triphosphatase in the peripheral blood lymphocytes of patients with hepatobiliary system pathology] causal interaction,diagnostic usage,ongoing research,unassigned 2,4,1,0 7.2.2.3 Hearing Loss http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24651716&form=6&db=m The Drosophila melanogaster Phospholipid Flippase dATP8B Is Required for Odorant Receptor Function. therapeutic application,unassigned 1,0 7.2.2.3 Hearing Loss http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25138102&form=6&db=m A missense variant of the ATP1A2 gene is associated with a novel phenotype of progressive sensorineural hearing loss associated with migraine. causal interaction,ongoing research,therapeutic application,unassigned 4,2,1,0 7.2.2.3 Hearing Loss http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29305691&form=6&db=m The CAPOS mutation in ATP1A3 alters Na/K-ATPase function and results in auditory neuropathy which has implications for management. causal interaction,unassigned 2,0 7.2.2.3 Hearing Loss http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30186120&form=6&db=m The Endocannabinoid/Cannabinoid Receptor 2 System Protects Against Cisplatin-Induced Hearing Loss. causal interaction,unassigned 1,0 7.2.2.3 Hearing Loss, Sensorineural http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6255727&form=6&db=m Inhibition of Na+,K+-stimulated ATPase in the cochlea of the guinea pig. A potential cause of disturbed inner ear function in terminal renal failure. causal interaction,ongoing research,therapeutic application,unassigned 1,2,2,0 7.2.2.3 Hearing Loss, Sensorineural http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25138102&form=6&db=m A missense variant of the ATP1A2 gene is associated with a novel phenotype of progressive sensorineural hearing loss associated with migraine. causal interaction,ongoing research,therapeutic application,unassigned 4,2,1,0 7.2.2.3 Hearing Loss, Sensorineural http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27313535&form=6&db=m The Influence of Na(+), K(+)-ATPase on Glutamate Signaling in Neurodegenerative Diseases and Senescence. causal interaction,unassigned 1,0 7.2.2.3 Hearing Loss, Sensorineural http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30409907&form=6&db=m Functional consequences of the CAPOS mutation E818K of Na+,K+-ATPase. unassigned - 7.2.2.3 Heart Defects, Congenital http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16946398&form=6&db=m Sodium pump reduction correlates with aortic clamp time in pediatric heart surgery. causal interaction,ongoing research,unassigned 1,2,0 7.2.2.3 Heart Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33947098&form=6&db=m Cardiac Glycosides as Immune System Modulators. causal interaction,therapeutic application,unassigned 4,3,0 7.2.2.3 Heart Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34442254&form=6&db=m Insect Collections as an Untapped Source of Bioactive Compounds-Fireflies (Coleoptera: Lampyridae) and Cardiotonic Steroids as a Proof of Concept. therapeutic application,unassigned 4,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=134861&form=6&db=m Comparison of heart sarcolemmal enzyme activities in normal and cardiomyopathic (UM-X7.1) hamsters. causal interaction,ongoing research,unassigned 2,1,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=139212&form=6&db=m The amino acid composition of actin and myosin and Ca2+-activated myosin adenosine triphosphatase in chronic canine congestive heart failure. unassigned - 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1089374&form=6&db=m Distribution of sodium and potassium in chronic obstructive pulmonary disease. causal interaction,unassigned 2,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2827453&form=6&db=m Human myocardial adenosine triphosphatase activities in health and heart failure. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,3,1 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4229256&form=6&db=m Association of depressed myofibrillar adenosine triphosphatase and reduced contractility in experimental heart failure. therapeutic application,unassigned 1,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7185847&form=6&db=m Magnesium treatment of diuretic-induced hyponatremia with a preliminary report of a new aldosterone-antagonist. ongoing research,unassigned 1,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7563097&form=6&db=m Significance of sodium pump isoforms in digitalis therapy. causal interaction,unassigned 1,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7900618&form=6&db=m Altered diastolic [Ca2+]i handling in human ventricular myocytes from patients with terminal heart failure. diagnostic usage,ongoing research,unassigned 1,2,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9476544&form=6&db=m Role of inositol 1,4,5-trisphosphate receptors in regulating apoptotic signaling and heart failure. causal interaction,ongoing research,unassigned 3,2,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9924855&form=6&db=m Isoform-specific alterations in cardiac and erythrocyte Na+,K+-ATPase activity induced by norepinephrine. causal interaction,diagnostic usage,unassigned 3,1,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10217649&form=6&db=m Reduced sodium pump alpha1, alpha3, and beta1-isoform protein levels and Na+,K+-ATPase activity but unchanged Na+-Ca2+ exchanger protein levels in human heart failure. unassigned - 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10856402&form=6&db=m Association of chronic congestive heart failure in humans with an intrinsic upregulation in skeletal muscle sarcoplasmic reticulum calcium ion adenosine triphosphatase activity. causal interaction,diagnostic usage,ongoing research,unassigned 3,1,1,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12023690&form=6&db=m Marinobufagenin, an endogenous ligand of alpha-1 sodium pump, is a marker of congestive heart failure severity. unassigned - 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12213990&form=6&db=m Mammalian cardenolides as biomarkers in congestive heart failure. causal interaction,diagnostic usage,unassigned 3,3,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12479230&form=6&db=m Sodium pump isoform expression in heart failure: implication for treatment. causal interaction,ongoing research,therapeutic application,unassigned 3,2,4,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=13860702&form=6&db=m Myofibrillar adenosine triphosphatase activity in congestive heart failure. unassigned - 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17239701&form=6&db=m Istaroxime, a stimulator of sarcoplasmic reticulum calcium adenosine triphosphatase isoform 2a activity, as a novel therapeutic approach to heart failure. therapeutic application,unassigned 3,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17239702&form=6&db=m Istaroxime: a new luso-inotropic agent for heart failure. causal interaction,therapeutic application,unassigned 1,4,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17706876&form=6&db=m Cardiotonic steroids on the road to anti-cancer therapy. causal interaction,therapeutic application,unassigned 4,4,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18022084&form=6&db=m Assist devices fail to reverse patterns of fetal gene expression despite beta-blockers. causal interaction,diagnostic usage,unassigned 4,3,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18203708&form=6&db=m Altered Na+/Ca2+-exchanger activity due to downregulation of Na+/K+-ATPase {alpha}2-isoform in heart failure. causal interaction,unassigned 2,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21763352&form=6&db=m Antiherpes activity of glucoevatromonoside, a cardenolide isolated from a Brazilian cultivar of Digitalis lanata. causal interaction,therapeutic application,unassigned 1,4,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21859838&form=6&db=m Digitoxin-induced cytotoxicity in cancer cells is mediated through distinct kinase and interferon signalling networks. causal interaction,therapeutic application,unassigned 3,4,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22955490&form=6&db=m Regulation of the cardiac sodium pump. causal interaction,therapeutic application,unassigned 1,1,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26769537&form=6&db=m Mitigation of myocardial fibrosis by molecular cardiac surgery-mediated gene overexpression. causal interaction,ongoing research,unassigned 3,4,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27031987&form=6&db=m Cardiac Glycosides Activate the Tumor Suppressor and Viral Restriction Factor Promyelocytic Leukemia Protein (PML). causal interaction,therapeutic application,unassigned 3,4,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28149313&form=6&db=m Effects of digoxin on cardiac iron content in rat model of iron overload. causal interaction,unassigned 4,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28164755&form=6&db=m Regulation of Na+/K+-ATPase by Estradiol and IGF-1 in Cardio-Metabolic Diseases. causal interaction,diagnostic usage,therapeutic application,unassigned 3,3,4,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28493895&form=6&db=m The cardiac glycoside ouabain activates NLRP3 inflammasomes and promotes cardiac inflammation and dysfunction. causal interaction,therapeutic application,unassigned 4,4,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29568394&form=6&db=m Cardiac glycoside bufalin blocks cancer cell growth by inhibition of Aurora A and Aurora B activation via PI3K-Akt pathway. causal interaction,therapeutic application,unassigned 4,4,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29762054&form=6&db=m Altered sarco(endo)plasmic reticulum calcium adenosine triphosphatase 2a content: Targets for heart failure therapy. causal interaction,therapeutic application,unassigned 4,2,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30579976&form=6&db=m Cardenolides: Insights from chemical structure and pharmacological utility. causal interaction,therapeutic application,unassigned 3,4,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31042565&form=6&db=m Cardiotonic steroid ouabain stimulates steroidogenesis in Leydig cells via the ?3 isoform of the sodium pump. causal interaction,therapeutic application,unassigned 3,4,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31170971&form=6&db=m Ouabain potentiates the antimicrobial activity of aminoglycosides against Staphylococcus aureus. causal interaction,therapeutic application,unassigned 3,2,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31527358&form=6&db=m [Cancer cell-specific functional relation between Na+,K+-ATPase and volume-regulated anion channel]. causal interaction,therapeutic application,unassigned 3,4,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34448639&form=6&db=m The ?2-isoform of the Na+/K+-ATPase protects against pathological remodeling and ?-adrenergic desensitization after myocardial infarction. causal interaction,therapeutic application,unassigned 4,2,0 7.2.2.3 Heart Failure http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34454876&form=6&db=m Cardiac Resynchronization and Circulating Markers of Sarcoplasmic Reticulum Calcium Handling and Sudden Death Risk. causal interaction,therapeutic application,unassigned 4,2,0 7.2.2.3 Hemiplegia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15174025&form=6&db=m Alternating hemiplegia of childhood or familial hemiplegic migraine? A novel ATP1A2 mutation. causal interaction,unassigned 2,0 7.2.2.3 Hemiplegia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15286158&form=6&db=m A novel mutation in the ATP1A2 gene causes alternating hemiplegia of childhood. causal interaction,unassigned 3,0 7.2.2.3 Hemiplegia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15534763&form=6&db=m Alternating hemiplegia of childhood: no mutations in the second familial hemiplegic migraine gene ATP1A2. unassigned - 7.2.2.3 Hemiplegia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17435187&form=6&db=m Prolonged hemiplegic episodes in children due to mutations in ATP1A2. diagnostic usage,unassigned 1,0 7.2.2.3 Hemiplegia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18811707&form=6&db=m 'Absence of T378N mutation of ATP1A2 gene in five patients with alternating hemiplegia of childhood'. unassigned - 7.2.2.3 Hemiplegia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20974584&form=6&db=m A long-term follow-up study of 18 patients with sporadic hemiplegic migraine. diagnostic usage,unassigned 1,0 7.2.2.3 Hemiplegia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24097848&form=6&db=m A Wide Clinical Phenotype Spectrum in Patients With ATP1A2 Mutations. causal interaction,ongoing research,unassigned 4,2,0 7.2.2.3 Hemiplegia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25476251&form=6&db=m Genome-wide screen for modifiers of Na + /K + ATPase alleles identifies critical genetic loci. causal interaction,therapeutic application,unassigned 3,1,0 7.2.2.3 Hemiplegia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25523819&form=6&db=m Knock-in mouse model of alternating hemiplegia of childhood: behavioral and electrophysiologic characterization. causal interaction,unassigned 3,0 7.2.2.3 Hemiplegia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25713066&form=6&db=m Rescue of Na+ Affinity in Aspartate-928 Mutants of Na+,K+-ATPase by Secondary Mutation of Glutamate-314. unassigned - 7.2.2.3 Hemiplegia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26501181&form=6&db=m Characterization of cognitive deficits in mice with an alternating hemiplegia-linked mutation. causal interaction,unassigned 2,0 7.2.2.3 Hemiplegia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27313535&form=6&db=m The Influence of Na(+), K(+)-ATPase on Glutamate Signaling in Neurodegenerative Diseases and Senescence. causal interaction,unassigned 1,0 7.2.2.3 Hemiplegia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28472154&form=6&db=m Hypothermia-induced dystonia and abnormal cerebellar activity in a mouse model with a single disease-mutation in the sodium-potassium pump. causal interaction,unassigned 1,0 7.2.2.3 Hemiplegia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28637637&form=6&db=m Alternating hemiplegia of childhood and a pathogenic variant of ATP1A3: a case report and pathophysiological considerations. causal interaction,unassigned 3,0 7.2.2.3 Hemiplegia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28811059&form=6&db=m An Infant With Epilepsy and Recurrent Hemiplegia due to Compound Heterozygous Variants in ATP1A2. causal interaction,unassigned 4,0 7.2.2.3 Hemiplegia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30071271&form=6&db=m Novel E815K knock-in mouse model of alternating hemiplegia of childhood. causal interaction,unassigned 1,0 7.2.2.3 Hemiplegia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30690204&form=6&db=m Biallelic loss of function variants in ATP1A2 cause hydrops fetalis, microcephaly, arthrogryposis and extensive cortical malformations. causal interaction,unassigned 1,0 7.2.2.3 Hemiplegia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31608932&form=6&db=m A novel lethal recognizable polymicrogyric syndrome caused by ATP1A2 homozygous truncating variants. causal interaction,unassigned 3,0 7.2.2.3 Hemiplegia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32653672&form=6&db=m Comparative analysis of alternating hemiplegia of childhood and rapid-onset dystonia-parkinsonism ATP1A3 mutations reveals functional deficits, which do not correlate with disease severity. causal interaction,unassigned 1,0 7.2.2.3 Hemiplegia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33578253&form=6&db=m A novel ATP1A2 variant associated with severe stepwise regression, hemiplegia, epilepsy and movement disorders in two unrelated patients. ongoing research,therapeutic application,unassigned 1,1,0 7.2.2.3 Hemiplegia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33794876&form=6&db=m De novo ATP1A2 variants in two Chinese children with alternating hemiplegia of childhood upgraded the gene-disease relationship and variant classification: a case report. causal interaction,unassigned 2,0 7.2.2.3 Hemiplegia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33880529&form=6&db=m ATP1A2- and ATP1A3-associated early profound epileptic encephalopathy and polymicrogyria. causal interaction,therapeutic application,unassigned 4,1,0 7.2.2.3 Hemiplegia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34135856&form=6&db=m CACNA1A-Linked Hemiplegic Migraine in GLUT 1 Deficiency Syndrome: A Case Report. causal interaction,unassigned 1,0 7.2.2.3 Hemoglobinuria http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4234910&form=6&db=m [Activity of adenosine triphosphatase of the erythrocytic membrane in paroxysmal nacturnal hemoglobinuria] unassigned - 7.2.2.3 Hepatic Encephalopathy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6319261&form=6&db=m Inhibition of rat brain Na+,K+-ATPase activity by serum from patients with fulminant hepatic failure. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,3,0 7.2.2.3 Hepatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2936473&form=6&db=m [The activities of acid phosphatase (ACP) and Mg++ adenosine triphosphatase in acute hepatitis with submassive necrosis] unassigned - 7.2.2.3 Hepatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2953083&form=6&db=m [Lactate dehydrogenase, glucosephosphate dehydrogenase, glutathione reductase and adenosine triphosphatase activities in the erythrocytes of patients with acute viral hepatitis] causal interaction,diagnostic usage,ongoing research,unassigned 1,1,1,0 7.2.2.3 Hepatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4328827&form=6&db=m [Histochemical studies of the effect of Meritschleri mineral water on the activity of lipase, cytochrome oxidase and adenosine triphosphatase enzymes in the liver in experimental hepatitis] ongoing research,unassigned 4,0 7.2.2.3 Hepatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7409385&form=6&db=m Sodium transport in red cells of patients with acute viral hepatitis. causal interaction,ongoing research,therapeutic application,unassigned 1,2,1,0 7.2.2.3 Hepatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7602937&form=6&db=m [The cytochemical determination of alpha-glycerophosphate dehydrogenase and adenosine triphosphatase in the peripheral blood lymphocytes of patients with hepatobiliary system pathology] causal interaction,diagnostic usage,ongoing research,unassigned 2,4,1,0 7.2.2.3 Hepatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32964796&form=6&db=m Coronavirus interactions with the cellular autophagy machinery. ongoing research,unassigned 1,0 7.2.2.3 Hepatitis B http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6161957&form=6&db=m Immune and enzyme histochemical studies of a human hepatocellular carcinoma cell line producing hepatitis B surface antigen. unassigned - 7.2.2.3 Hepatitis C http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12554059&form=6&db=m Antigenicity of a recombinant NS3 protein representative of ATPase/helicase domain from hepatitis C virus. ongoing research,therapeutic application,unassigned 2,3,0 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7785328&form=6&db=m Sequence, mapping and disruption of CCC2, a gene that cross-complements the Ca(2+)-sensitive phenotype of csg1 mutants and encodes a P-type ATPase belonging to the Cu(2+)-ATPase subfamily. causal interaction,unassigned 1,0 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7814642&form=6&db=m Adenosine triphosphate-dependent copper transport in isolated rat liver plasma membranes. ongoing research,unassigned 2,0 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7937823&form=6&db=m P-type ATPase from the cyanobacterium Synechococcus 7942 related to the human Menkes and Wilson disease gene products. ongoing research,unassigned 3,0 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8091505&form=6&db=m Wilson disease and Menkes disease: new handles on heavy-metal transport. unassigned - 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8250934&form=6&db=m Isolation and characterization of a human liver cDNA as a candidate gene for Wilson disease. causal interaction,therapeutic application,unassigned 4,3,0 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8836899&form=6&db=m Adenosine triphosphate-dependent copper transport in human liver. unassigned - 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9554743&form=6&db=m Identification of three novel mutations and a high frequency of the Arg778Leu mutation in Korean patients with Wilson disease. ongoing research,unassigned 1,0 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10212214&form=6&db=m Role of the copper-binding domain in the copper transport function of ATP7B, the P-type ATPase defective in Wilson disease. unassigned - 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10579979&form=6&db=m Localization of the Wilson's disease protein in human liver. ongoing research,therapeutic application,unassigned 4,1,0 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10790207&form=6&db=m Mutational analysis of ATP7B and genotype-phenotype correlation in Japanese with Wilson's disease. diagnostic usage,unassigned 2,0 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10981891&form=6&db=m Oxidative-phosphorylation defects in liver of patients with Wilson's disease. causal interaction,unassigned 3,0 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10982773&form=6&db=m Copper-induced apical trafficking of ATP7B in polarized hepatoma cells provides a mechanism for biliary copper excretion. ongoing research,therapeutic application,unassigned 4,1,0 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11043508&form=6&db=m Molecular analysis of Wilson disease in Taiwan: identification of one novel mutation and evidence of haplotype-mutation association. causal interaction,unassigned 4,0 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11405812&form=6&db=m Mutation analysis and the correlation between genotype and phenotype of Arg778Leu mutation in chinese patients with Wilson disease. unassigned - 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11579422&form=6&db=m Mitochondria and degenerative disorders. causal interaction,unassigned 3,0 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11936861&form=6&db=m Disturbed copper transport in humans. Part 2: mutations of the ATP7B gene lead to Wilson disease (WD). unassigned - 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12955875&form=6&db=m Diagnosis and phenotypic classification of Wilson disease. ongoing research,therapeutic application,unassigned 2,1,0 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15024742&form=6&db=m Wilson disease: novel mutations in the ATP7B gene and clinical correlation in Brazilian patients. causal interaction,unassigned 3,0 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15998441&form=6&db=m Efficacy of zinc supplementation in preventing acute hepatitis in Long-Evans Cinnamon rats. unassigned - 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16269323&form=6&db=m Ceruloplasmin in neurodegenerative diseases. causal interaction,diagnostic usage,unassigned 4,2,0 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16416207&form=6&db=m A new mutation of Wilson's disease P-type ATPase gene in a patient with cirrhosis and coombs-positive hemolytic anemia. unassigned - 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16554302&form=6&db=m Copper-dependent interaction of dynactin subunit p62 with the N terminus of ATP7B but not ATP7A. unassigned - 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17317524&form=6&db=m Late neurological presentations of Wilson disease patients in French population and identification of 8 novel mutations in the ATP7B gene. causal interaction,therapeutic application,unassigned 1,1,0 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17876883&form=6&db=m Wilson disease: identification of two novel mutations and clinical correlation in Eastern Chinese patients. diagnostic usage,ongoing research,unassigned 1,2,0 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17910951&form=6&db=m Developmental expression of Commd1 in the liver of the Jackson toxic milk mouse. causal interaction,unassigned 4,0 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17919502&form=6&db=m Distinct Wilson's disease mutations in ATP7B are associated with enhanced binding to COMMD1 and reduced stability of ATP7B. causal interaction,unassigned 3,0 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18789784&form=6&db=m [The onset of psychiatric disorders and Wilson's disease] unassigned - 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19306278&form=6&db=m Monozygotic female twins discordant for phenotype of Wilson's disease. causal interaction,unassigned 1,0 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19520855&form=6&db=m High yield heterologous expression of wild-type and mutant Cu+-ATPase (ATP7B, Wilson disease protein) for functional characterization of catalytic activity and serine residues undergoing copper-dependent phosphorylation. diagnostic usage,ongoing research,therapeutic application,unassigned 1,2,1,0 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19783880&form=6&db=m [Haplotype analysis and possible founder effect at the R778L mutation of the ATP7B gene in Korean patients with Wilson's disease.] diagnostic usage,ongoing research,unassigned 1,2,0 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20517649&form=6&db=m Genetic analysis of BIRC4/XIAP as a putative modifier gene of Wilson disease. unassigned - 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20799727&form=6&db=m NMR Characterization of Copper-Binding Domains 4-6 of ATP7B . unassigned - 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20931554&form=6&db=m Mutation analysis and characterization of alternative splice variants of the Wilson disease gene ATP7B. causal interaction,ongoing research,unassigned 3,3,0 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22240481&form=6&db=m Diverse Functional Properties of Wilson Disease ATP7B Variants. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,1,4,1 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23556051&form=6&db=m Genetically confirmed Wilson disease in a 9-month old boy with elevations of aminotransferases. causal interaction,unassigned 3,0 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23774950&form=6&db=m Concordance rates of Wilson's disease phenotype among siblings. unassigned - 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25465132&form=6&db=m Gene mutations in Wilson disease in Egyptian children: report on two novel mutations. causal interaction,unassigned 1,0 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27398169&form=6&db=m Mutational analysis of ATP7B in Chinese Wilson disease patients. causal interaction,diagnostic usage,unassigned 3,4,0 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27455805&form=6&db=m [Copper metabolism and genetic disorders]. unassigned - 7.2.2.3 Hepatolenticular Degeneration http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27706781&form=6&db=m Direct sequencing of mutations in the copper-transporting P-type adenosine triphosphate (ATP7B) gene for diagnosis and pathogenesis of Wilson's disease. diagnostic usage,unassigned 1,0 7.2.2.3 Herpes Simplex http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25004&form=6&db=m Some properties of the adenosine triphosphatase associated with herpes simplex virus and nuclear membrane of host cells. ongoing research,therapeutic application,unassigned 3,1,0 7.2.2.3 Herpes Simplex http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6112862&form=6&db=m Solubilization of adenosine triphosphatase associated with herpes simplex virus. ongoing research,unassigned 3,0 7.2.2.3 Herpes Simplex http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10601266&form=6&db=m The herpes simplex virus type 1 origin-binding protein. sequence-specific activation of adenosine triphosphatase activity by a double-stranded DNA containing box I. ongoing research,unassigned 1,0 7.2.2.3 Herpes Simplex http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32964796&form=6&db=m Coronavirus interactions with the cellular autophagy machinery. ongoing research,unassigned 1,0 7.2.2.3 Herpes Zoster http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16820940&form=6&db=m Ouabain chronic infusion enhances the growth and steroidogenic capacity of rat adrenal zona glomerulosa: the possible involvement of the endothelin system. therapeutic application,unassigned 3,0 7.2.2.3 Herpes Zoster http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25139734&form=6&db=m Mesothelial cells: a cellular surrogate for tissue engineering of corneal endothelium. unassigned - 7.2.2.3 Herpes Zoster http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28928909&form=6&db=m Transplanting embryonic stem cells onto damaged human corneal endothelium. therapeutic application,unassigned 1,0 7.2.2.3 Histiocytoma, Malignant Fibrous http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6297258&form=6&db=m Enzyme histochemical study on bone tumors. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,1,2 7.2.2.3 Histiocytosis, Langerhans-Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6381283&form=6&db=m Histiocytosis X cells and Langerhans cells: enzyme histochemical and immunologic similarities. ongoing research,unassigned 3,0 7.2.2.3 Homocystinuria http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15128185&form=6&db=m In vitro homocysteine inhibits platelet Na+,K+-ATPase and serum butyrylcholinesterase activities of young rats. diagnostic usage,ongoing research,unassigned 1,4,0 7.2.2.3 Homocystinuria http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15245753&form=6&db=m In vivo and in vitro effects of homocysteine on Na+, K+-ATPase activity in parietal, prefrontal and cingulate cortex of young rats. causal interaction,therapeutic application,unassigned 4,1,0 7.2.2.3 Huntington Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=211930&form=6&db=m Increased sodium plus potassium adenosine triphosphatase activity in erythrocyte membranes in Huntington's disease. diagnostic usage,ongoing research,unassigned 3,2,0 7.2.2.3 Huntington Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6251175&form=6&db=m Specificity of biophysical and biochemical alterations in erythrocyte membranes in neurological disorders--Huntington's disease, Friedreich's ataxia, Alzheimer's disease, amyotrophic lateral sclerosis, and myotonic and duchenne muscular dystrophy. diagnostic usage,therapeutic application,unassigned 3,1,0 7.2.2.3 Hydrops Fetalis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30690204&form=6&db=m Biallelic loss of function variants in ATP1A2 cause hydrops fetalis, microcephaly, arthrogryposis and extensive cortical malformations. causal interaction,unassigned 1,0 7.2.2.3 Hydrops Fetalis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33880529&form=6&db=m ATP1A2- and ATP1A3-associated early profound epileptic encephalopathy and polymicrogyria. causal interaction,therapeutic application,unassigned 4,1,0 7.2.2.3 Hyperaldosteronism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1649866&form=6&db=m Does a digoxin-like substance participate in vascular and pressure control during dietary sodium changes in patients with primary aldosteronism? diagnostic usage,ongoing research,unassigned 2,1,0 7.2.2.3 Hyperaldosteronism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2449394&form=6&db=m Sodium transport parameters in erythrocytes of patients with primary aldosteronism. causal interaction,diagnostic usage,ongoing research,unassigned 4,2,3,0 7.2.2.3 Hyperaldosteronism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3193658&form=6&db=m Intracellular sodium and potassium concentrations in erythrocytes of patients with primary aldosteronism. causal interaction,unassigned 4,0 7.2.2.3 Hypercholesterolemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2542284&form=6&db=m Influence of sterols and phospholipids on sarcolemmal and sarcoplasmic reticular cation transporters. unassigned - 7.2.2.3 Hyperemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23940309&form=6&db=m Reactive Hyperemia Occurs Via Activation of Inwardly Rectifying Potassium Channels and Na+/K+-ATPase in Humans. unassigned - 7.2.2.3 Hyperemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34473573&form=6&db=m Na+/K+-ATPase plays a major role in mediating cutaneous thermal hyperemia achieved by local skin heating to 39 ºC. causal interaction,ongoing research,therapeutic application,unassigned 3,1,1,0 7.2.2.3 Hyperhomocysteinemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18023318&form=6&db=m Concurrent folate treatment prevents Na+,K+-ATPase activity inhibition and memory impairments caused by chronic hyperhomocysteinemia during rat development. causal interaction,therapeutic application,unassigned 3,2,0 7.2.2.3 Hyperinsulinism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=101072&form=6&db=m Criteria for choosing amino acid therapy in acute renal failure. unassigned - 7.2.2.3 Hyperinsulinism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2220797&form=6&db=m Diabetes mellitus and hypertension. causal interaction,therapeutic application,unassigned 3,2,0 7.2.2.3 Hyperinsulinism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8929644&form=6&db=m Association of sick sinus syndrome with hyperinsulinemia and insulin resistance in patients with non-insulin-dependent diabetes mellitus: report of four cases. causal interaction,unassigned 3,0 7.2.2.3 Hyperkalemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1313528&form=6&db=m Reduction of erythrocyte (Na(+)-K+) ATPase activities in non-insulin-dependent diabetic patients with hyperkalemia. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,3,0 7.2.2.3 Hyperkalemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6206353&form=6&db=m The role of a humoral Na+,K+-ATPase inhibitor in regulating precapillary vessel tone. causal interaction,therapeutic application,unassigned 4,4,0 7.2.2.3 Hyperkalemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12660435&form=6&db=m Digoxin-like immunoreactive substance in nonoliguric hyperkalemia of the premature infant. causal interaction,therapeutic application,unassigned 1,2,0 7.2.2.3 Hyperkalemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18227802&form=6&db=m Altered fluid, electrolyte and mineral status in tropical disease, with an emphasis on malaria and leptospirosis. unassigned - 7.2.2.3 Hyperkalemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18430962&form=6&db=m Frontiers: skeletal muscle sodium pump regulation: a translocation paradigm. causal interaction,ongoing research,therapeutic application,unassigned 1,1,1,0 7.2.2.3 Hyperlactatemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22180135&form=6&db=m Lactate production and measurement in critically ill horses. causal interaction,therapeutic application,unassigned 4,1,0 7.2.2.3 Hyperprolactinemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28601073&form=6&db=m Role of Na+/K(+)-ATPase in Natriuretic Effect of Prolactin in a Model of Cholestasis of Pregnancy. ongoing research,unassigned 4,0 7.2.2.3 Hypersensitivity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1847156&form=6&db=m A circulating inhibitor of the platelet Na+,K+ adenosine triphosphatase (ATPase) enzyme in allergy. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,1,2,3 7.2.2.3 Hypersensitivity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6221704&form=6&db=m [Activity of acid and alkaline phosphatases and adenosine triphosphatase in secondary allergy before and after treatment with hydrocortisone] therapeutic application,unassigned 3,0 7.2.2.3 Hypersensitivity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9058693&form=6&db=m The relationship between airway hyperreactivity (AHR) and sodium, potassium adenosine triphosphatase (Na+,K+ ATPase) enzyme inhibition. diagnostic usage,ongoing research,unassigned 3,2,0 7.2.2.3 Hypersensitivity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18294248&form=6&db=m Familial hemiplegic migraine type 2 does not share hypersensitivity to nitric oxide with common types of migraine. causal interaction,unassigned 4,0 7.2.2.3 Hypersensitivity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22906851&form=6&db=m Antiarrhythmic drug amiodarone displays antifungal activity, induces irregular calcium response and intracellular acidification of Aspergillus niger - Amiodarone targets calcium and pH homeostasis of A. niger. causal interaction,therapeutic application,unassigned 3,1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=533673&form=6&db=m Commentary. The sodium pump in cardiovascular muscle in hypertension: whose hypothesis? therapeutic application,unassigned 1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1329936&form=6&db=m Pregnancy induced hypertension and sodium pump function in erythrocytes. diagnostic usage,ongoing research,therapeutic application,unassigned 4,2,1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1649866&form=6&db=m Does a digoxin-like substance participate in vascular and pressure control during dietary sodium changes in patients with primary aldosteronism? diagnostic usage,ongoing research,unassigned 2,1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1656137&form=6&db=m Membrane transport, sodium balance, and blood pressure regulation. diagnostic usage,therapeutic application,unassigned 2,1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1657500&form=6&db=m Low-concentration ouabain does not inhibit noradrenaline-induced contraction of human resistance arteries. causal interaction,therapeutic application,unassigned 3,4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1660956&form=6&db=m Vascular sodium pump activity kinetics in early and advanced stages of deoxycorticosterone-salt hypertension in rats. causal interaction,diagnostic usage,therapeutic application,unassigned 4,3,1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1737652&form=6&db=m Magnesium supplementation prevents the development of alcohol-induced hypertension. causal interaction,unassigned 3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2102717&form=6&db=m [Changes in the glycolytic pathway in patients with essential arterial hypertension] diagnostic usage,unassigned 2,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2154403&form=6&db=m Race, sex, and family history of hypertension and erythrocyte sodium pump [3H]ouabain binding. diagnostic usage,unassigned 3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2196126&form=6&db=m Increased activity of digoxin-like substance in low-renin hypertension in acromegaly. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,2,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2404857&form=6&db=m Lenticular rubidium uptake and plasma renin activity in weanling cataract-prone salt-sensitive rats. causal interaction,diagnostic usage,ongoing research,unassigned 1,1,3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2411605&form=6&db=m Evidence for a circulating endogenous Na+-K+ pump inhibitor in low-renin hypertension. causal interaction,ongoing research,therapeutic application,unassigned 4,4,4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2424543&form=6&db=m Reversible inhibition of leucocyte sodium pumps by a circulating serum factor in essential hypertension. causal interaction,therapeutic application,unassigned 4,3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2439743&form=6&db=m Natriuretic hormones in low renin hypertension. causal interaction,unassigned 3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2439746&form=6&db=m Sodium pump activity in young and adult salt hypertensive Dahl rats. ongoing research,unassigned 1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2445679&form=6&db=m Vascular muscle membrane cation mechanisms and total peripheral resistance. causal interaction,unassigned 3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2447462&form=6&db=m Pharmacologic agents for the in vivo detection of vascular sodium transport defects in hypertension. unassigned - 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2547398&form=6&db=m Facilitatory effects of ouabain and digitalis-like substance on adrenergic transmission in hypertension. causal interaction,ongoing research,therapeutic application,unassigned 1,4,1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2547400&form=6&db=m Effect of dietary sodium on the Na-K ATPase inhibitor in patients with essential hypertension. causal interaction,ongoing research,therapeutic application,unassigned 3,2,3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2552338&form=6&db=m [Physiologic role of the sodium pump. Implications for the study of arterial hypertension] causal interaction,ongoing research,therapeutic application,unassigned 1,2,2,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2579261&form=6&db=m Studies on the role of sodium- and potassium-activated adenosine triphosphatase inhibition in the pathogenesis of human hypertension. Changes in vascular and cardiac function following inhibition of the sodium pump in normotensive subjects and effects of calcium entry blockade. causal interaction,ongoing research,therapeutic application,unassigned 4,3,1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2582725&form=6&db=m Sympathetic vasoconstriction as a mechanism of action of ouabain in forearm arterioles of hypertensive patients. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,2,1,2 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2612017&form=6&db=m Leucocyte sodium content and sodium pump activity in overweight and lean hypertensives. causal interaction,diagnostic usage,ongoing research,unassigned 4,1,3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2661427&form=6&db=m Erythrocyte sodium transport and blood pressure in white subjects. causal interaction,unassigned 3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2671214&form=6&db=m Salt and hypertension: recent advances and perspectives. unassigned - 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2821695&form=6&db=m [Is there a relation between the presence in the serum of patients with arterial hypertension of a protein component with molecular weight of 15 kD and the inhibitory effect of the serum on Na,K-ATPase?] causal interaction,diagnostic usage,ongoing research,therapeutic application 2,3,4,1 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2821951&form=6&db=m [Genetic hypertension in the SHR rat and circulating digitalis compounds] ongoing research,therapeutic application,unassigned 4,1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2824366&form=6&db=m Ouabainlike Na+,K+-ATPase inhibitor in the plasma of normotensive and hypertensive humans and rats. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,1,2,3 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2824367&form=6&db=m Problems and pitfalls in the isolation of an endogenous Na+, K+-ATPase inhibitor. causal interaction,ongoing research,therapeutic application,unassigned 4,1,2,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2824371&form=6&db=m Humoral sodium transport inhibitor in acute volume expansion and low renin hypertension. causal interaction,ongoing research,therapeutic application,unassigned 3,2,4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2824372&form=6&db=m Endogenous cardiac glycosidelike compounds. causal interaction,unassigned 3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2831002&form=6&db=m Potassium, Na+-K+ pump inhibitor and low-renin hypertension. causal interaction,diagnostic usage,therapeutic application,unassigned 1,2,4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2834572&form=6&db=m Effects of ouabain on adrenergic neurotransmission in spontaneously hypertensive rats. causal interaction,ongoing research,unassigned 1,3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2841315&form=6&db=m Na+/K+-ATPase regulation in Dahl salt-sensitive and salt-resistant rats. causal interaction,therapeutic application,unassigned 4,4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2843200&form=6&db=m Characterization of a Na+/K+-ATPase inhibitor from human plasma: preliminary data. causal interaction,therapeutic application,unassigned 4,3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2844224&form=6&db=m Isolation and characterization of a specific endogenous Na+,K+-ATPase inhibitor from bovine adrenal. diagnostic usage,ongoing research,therapeutic application,unassigned 3,4,1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2846215&form=6&db=m Abnormalities in the sodium transport as the causative factor for enhanced norepinephrine overflow in the spontaneously hypertensive rat. causal interaction,therapeutic application,unassigned 4,2,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2847188&form=6&db=m Species sensitivity of the sodium pump to a circulating ouabain-like inhibitor in acute hypervolemia and DOCA hypertension: comparison with ouabain. ongoing research,therapeutic application,unassigned 1,3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2849538&form=6&db=m Effects of lead and natriuretic hormone on kinetics of sodium-potassium-activated adenosine triphosphatase: possible relevance to hypertension. causal interaction,ongoing research,therapeutic application,unassigned 4,3,1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2849788&form=6&db=m The role of vascular Na,K-ATPase activity in salt induced hypertension in Dahl rats. causal interaction,ongoing research,unassigned 1,2,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2853745&form=6&db=m Ouabain vasoconstricts human forearm arterioles through alpha-adrenergic stimulation. causal interaction,ongoing research,therapeutic application,unassigned 1,1,4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2856819&form=6&db=m Salt sensitivity in normotensives with family history of hypertension: studies of membrane transport, intracellular electrolytes and alpha 2-adrenergic receptors. causal interaction,diagnostic usage,ongoing research,unassigned 1,2,2,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2856822&form=6&db=m Vascular smooth muscle membrane potentials in rats with one-kidney, one clip and reduced renal mass-saline hypertension: the influence of a humoral sodium pump inhibitor. therapeutic application,unassigned 2,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2930228&form=6&db=m Sodium transport in erythrocytes: differences between normal children and children with primary and secondary hypertension. diagnostic usage,unassigned 1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2950755&form=6&db=m Epidemiological evidence associating dietary calcium and calcium metabolism with blood pressure. unassigned - 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2987607&form=6&db=m Raised sodium pump activity and a circulating sodium transport inhibitor demonstrated on red blood cells of patients with untreated essential hypertension: correlation of pump activity with potassium permeability. diagnostic usage,ongoing research,therapeutic application,unassigned 4,3,2,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2989396&form=6&db=m Sodium-potassium-adenosine triphosphatase in nephron segments of spontaneously hypertensive rats. causal interaction,therapeutic application,unassigned 3,2,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2990769&form=6&db=m Plasma Na+-K+ ATPase inhibitory activity in normal and hypertensive subjects: relationship to intracellular electrolytes and blood pressure. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,2,2,2 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2990771&form=6&db=m The role of endogenous inhibition of Na-K-ATPase in human hypertension--sodium pump activity as a determinant of peripheral vascular resistance. causal interaction,diagnostic usage,ongoing research,unassigned 4,1,2,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2991692&form=6&db=m In ability of Na+,K+-ATPase inhibitor to cause hypertension in sodium-loaded or deoxycorticosterone-treated one kidney rats. causal interaction,ongoing research,therapeutic application,unassigned 1,2,4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2993163&form=6&db=m Demonstration of a ouabainlike plasma compound in hypertension prone and hypertension resistant rats. diagnostic usage,ongoing research,unassigned 3,2,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2997539&form=6&db=m [Hereditary salt sensitivity as a cause of essential hypertension: studies of membrane transport and intracellular electrolytes] causal interaction,ongoing research,unassigned 1,1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3025522&form=6&db=m Lack of effect of acute alcohol ingestion on erythrocyte Na+, K+ -ATPase activity or passive sodium uptake in vivo in man. causal interaction,therapeutic application,unassigned 3,1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3028785&form=6&db=m Further biochemical characterization of an Na+ pump inhibitor purified from human urine. causal interaction,therapeutic application,unassigned 3,1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3034452&form=6&db=m Measurement by bioluminescence technique of erythrocyte membrane Na+,K+-ATPase activity in hypertensive patients. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,2,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3040586&form=6&db=m Erythrocyte ghost Na+,K+-ATPase and blood pressure. unassigned - 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3193658&form=6&db=m Intracellular sodium and potassium concentrations in erythrocytes of patients with primary aldosteronism. causal interaction,unassigned 4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3333521&form=6&db=m Effects of manipulation of sodium balance on erythrocyte sodium transport. therapeutic application,unassigned 2,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3415795&form=6&db=m Endogenous digitalislike substance in an adult population in Japan. causal interaction,unassigned 4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3430690&form=6&db=m The role of chloride on deoxycorticosterone acetate-salt hypertension. therapeutic application,unassigned 3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3588654&form=6&db=m Sodium pump activity and norepinephrine responsiveness of femoral arterial smooth muscle from DOCA-salt rats. unassigned - 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3608370&form=6&db=m Platelet sodium kinetics, blood pressure and serum urate: aberrations in non-obese men at risk for type 2 diabetes mellitus. causal interaction,unassigned 4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3734450&form=6&db=m Effects of changes in sodium balance on leucocyte sodium transport: qualitative differences in normotensive offspring of hypertensives and matched controls. therapeutic application,unassigned 3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3969857&form=6&db=m Functional differences in blood vessels determined from studies with calcium-channel blockers. Functional changes in forearm resistance vessels of men with primary hypertension. causal interaction,unassigned 1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3999641&form=6&db=m Altered erythrocyte cation transport related to hypertension or oral contraception. unassigned - 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4017267&form=6&db=m Observations on the "cascade" of Na-K-ATPase inhibitory and digoxin-like immunoreactive material in human urine: possible relevance to essential hypertension. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,2,1 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4267732&form=6&db=m [(Na + --K + )-dependent adenosine triphosphatase in the renal medulla and cortex of rabbits with ischemic cerebral hypertension] causal interaction,unassigned 2,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6088115&form=6&db=m Phasic vascular sodium pump changes in deoxycorticosterone-hypertensive rats. causal interaction,unassigned 4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6088130&form=6&db=m Na+,K+-ATPase activity and responsiveness of vascular smooth muscle to norepinephrine, angiotensin II and calcium ionophore A23187 in guinea pig aortic strips. causal interaction,therapeutic application,unassigned 1,1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6126751&form=6&db=m Leucocyte membrane sodium transport in normotensive populations: dissociation of abnormalities of sodium efflux from raised blood-pressure. diagnostic usage,unassigned 2,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6204159&form=6&db=m Plasma sodium pump inhibitor in essential hypertension and normotensive subjects with hypertensive heredity. causal interaction,therapeutic application,unassigned 4,3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6206353&form=6&db=m The role of a humoral Na+,K+-ATPase inhibitor in regulating precapillary vessel tone. causal interaction,therapeutic application,unassigned 4,4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6279497&form=6&db=m Function of the sodium pump in arterial smooth muscle in experimental hypertension: role of pressure. ongoing research,therapeutic application,unassigned 2,3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6292736&form=6&db=m Hypertension and inhibition of the sodium pump: a strong link but in which chain? therapeutic application,unassigned 1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6303176&form=6&db=m Sodium-potassium pump in low-renin hypertension. causal interaction,therapeutic application,unassigned 3,4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6327514&form=6&db=m Three red cell sodium transport systems in hypertensive and normotensive Utah adults. ongoing research,unassigned 2,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6345202&form=6&db=m The role of a humoral sodium-potassium pump inhibitor in low-renin hypertension. causal interaction,ongoing research,therapeutic application,unassigned 4,2,4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6360883&form=6&db=m Abnormalities of membrane transport in hypertension. diagnostic usage,unassigned 3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6416434&form=6&db=m Calcium antagonists in hypertension: relation to abnormal sodium transport. therapeutic application,unassigned 4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6681036&form=6&db=m Effect of local infusion of ouabain on human forearm vascular resistance and on response to potassium, verapamil and sodium nitroprusside. causal interaction,therapeutic application,unassigned 3,2,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6692657&form=6&db=m The dilator response to K+ is reduced in the forearm resistance vessels of men with primary hypertension. causal interaction,diagnostic usage,therapeutic application,unassigned 3,2,1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6731036&form=6&db=m Potassium in skeletal muscle in untreated primary hypertension and in chronic renal failure, studied by X-ray fluorescence technique. causal interaction,unassigned 4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7037634&form=6&db=m Sodium pump activity in arteries of rats with Goldblatt hypertension. causal interaction,ongoing research,unassigned 4,2,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7251090&form=6&db=m Sodium pump activity in arteries of Dahl salt-sensitive rats. causal interaction,therapeutic application,unassigned 1,2,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7449259&form=6&db=m Leucocyte electrolytes and sodium efflux rate constants in the hypertension of pre-eclampsia. causal interaction,unassigned 4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7848616&form=6&db=m Sustained volume expansion and [Na,K]ATPase inhibition in chronic renal failure. therapeutic application,unassigned 1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7850405&form=6&db=m The sodium pump in hypertension. causal interaction,therapeutic application,unassigned 4,1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8613222&form=6&db=m Acute Na+,K+-ATPase inhibition with bufalin impairs pressure natriuresis in the rat. causal interaction,therapeutic application,unassigned 4,3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8613248&form=6&db=m Regulation of Na+,K+-ATPase alpha-subunit expression by mechanical strain in aortic smooth muscle cells. causal interaction,unassigned 4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8676814&form=6&db=m Dietary salt, intracellular ion homeostasis and hypertension secondary to early-stage kidney disease. causal interaction,unassigned 4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8704112&form=6&db=m Relationship of Na-K-ATPase inhibitors to blood-pressure regulation in continuous ambulatory peritoneal dialysis and hemodialysis. causal interaction,therapeutic application,unassigned 3,3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8754202&form=6&db=m Endogenous sodium pump inhibition: current status and therapeutic opportunities. unassigned - 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8793692&form=6&db=m Effect of ageing and hypertension on endothelial modulation of ouabain-induced contraction and sodium pump activity in the rat aorta. diagnostic usage,ongoing research,unassigned 2,4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8818921&form=6&db=m Erythrocyte sodium transport and the probability of having hypertension. diagnostic usage,ongoing research,unassigned 3,2,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8834705&form=6&db=m Reversal of sodium pump inhibitor induced vascular smooth muscle contraction with digibind. Stoichiometry and its implications. causal interaction,ongoing research,therapeutic application,unassigned 3,1,4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9086292&form=6&db=m Sodium pump and Na+/H+ activities in uremic erythrocytes. A microcalorimetric and pH-metric study. ongoing research,unassigned 1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9160763&form=6&db=m Renal sodium pump regulation in deoxycorticosterone salt hypertension in the rat. ongoing research,unassigned 4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9370384&form=6&db=m Tissue-specific regulation of the sodium pump in DOCA-salt hypertension. unassigned - 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9443778&form=6&db=m The role of sodium-potassium adenosine triphosphatase in the regulation of membrane fluidity of erythrocytes in spontaneously hypertensive rats: an electron paramagnetic resonance investigation. ongoing research,unassigned 4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9682906&form=6&db=m Role of ouabain-like factors and Na-K-ATPase inhibitors in hypertension--some old and recent findings. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,2,3,3 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9704761&form=6&db=m Regulation of the sodium pump in pregnancy-related tissues in preeclampsia. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,4,1 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9749562&form=6&db=m Effect of mechanical strain on expression of Na+,K+-ATPase alpha subunits in rat aortic smooth muscle cells. ongoing research,unassigned 2,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10232504&form=6&db=m Regulation of blood pressure during long-term ouabain infusion in Long-Evans rats. ongoing research,therapeutic application,unassigned 4,1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10466462&form=6&db=m Altered sodium pump alpha and gamma subunit gene expression in nephron segments from hypertensive rats. causal interaction,unassigned 4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10466474&form=6&db=m Circulating bufodienolide and cardenolide sodium pump inhibitors in preeclampsia. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,3,2,3 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10567200&form=6&db=m Sodium pump inhibition and regional expression of sodium pump alpha-isoforms in lens. causal interaction,unassigned 4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10694190&form=6&db=m Cicletanine reverses vasoconstriction induced by the endogenous sodium pump ligand, marinobufagenin, via a protein kinase C dependent mechanism. causal interaction,unassigned 3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10821337&form=6&db=m Inhibitors of Na-K-ATPase in human urine: effects of ouabain-like factors and of vanadium-diascorbate on calcium mobilization in rat vascular smooth muscle cells: comparison with the effects of ouabain, angiotensin II, and arginine-vasopressin. causal interaction,unassigned 3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10919857&form=6&db=m Proximal tubule Na transporter responses are the same during acute and chronic hypertension. causal interaction,ongoing research,therapeutic application,unassigned 4,2,1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11016821&form=6&db=m Differential regulation of the sodium pump alpha-subunit isoform gene by ouabain and digoxin in tissues of rats. causal interaction,unassigned 1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11226512&form=6&db=m Chloride in smooth muscle. unassigned - 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11230321&form=6&db=m Structure-activity relationships for the hypertensinogenic activity of ouabain: role of the sugar and lactone ring. causal interaction,therapeutic application,unassigned 3,3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11276400&form=6&db=m Regulation of sodium/potassium ATPase activity: impact on salt balance and vascular contractility. causal interaction,unassigned 3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11355001&form=6&db=m Endogenous cardiotonic steroids. causal interaction,therapeutic application,unassigned 3,3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11357900&form=6&db=m Abnormalities of sodium pump function in hypertension and the role of endogenous cardiotonic steroids. causal interaction,ongoing research,unassigned 4,2,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11470086&form=6&db=m Expression of sodium pump isoforms and other sodium or calcium ion transporters in the heart of hypertensive patients. unassigned - 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11487094&form=6&db=m Digitalis-like factor response to hyperinsulinemia accompanying a euglycemic hyperinsulinemic clamp or oral glucose tolerance test. causal interaction,diagnostic usage,therapeutic application,unassigned 4,3,1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11675399&form=6&db=m Downstream shift in sodium pump activity along the nephron during acute hypertension. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,1,1 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11834625&form=6&db=m Alterations in phenylephrine-induced contractions and the vascular expression of Na+,K+-ATPase in ouabain-induced hypertension. unassigned - 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11877366&form=6&db=m Endogenous ligand of alpha(1) sodium pump, marinobufagenin, is a novel mediator of sodium chloride--dependent hypertension. unassigned - 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12522466&form=6&db=m Digitalis-like factor response to hyperinsulinemia in human pregnancy, a model of insulin resistance. causal interaction,unassigned 3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12907130&form=6&db=m Mechanism of garlic (Allium sativum) induced reduction of hypertension in 2K-1C rats: a possible mediation of Na/H exchanger isoform-1. ongoing research,unassigned 4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15009217&form=6&db=m Ouabain stimulates endothelin release and expression in human endothelial cells without inhibiting the sodium pump. causal interaction,therapeutic application,unassigned 3,3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15142663&form=6&db=m Marinobufagenin may mediate the impact of salty diets on left ventricular hypertrophy by disrupting the protective function of coronary microvascular endothelium. unassigned - 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15173126&form=6&db=m Altered subcellular distribution of Na+,K+-ATPase in proximal tubules in young spontaneously hypertensive rats. causal interaction,unassigned 4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15233981&form=6&db=m New ouabain-conjugated peptide found from phage displayed peptide library. ongoing research,therapeutic application,unassigned 2,1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15276875&form=6&db=m Brain Na+,K+-ATPase isozyme activity and protein expression in ouabain-induced hypertension. diagnostic usage,ongoing research,unassigned 3,3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15528469&form=6&db=m Hypertension-linked mutation in the adducin alpha-subunit leads to higher AP2-mu2 phosphorylation and impaired Na+,K+-ATPase trafficking in response to GPCR signals and intracellular sodium. unassigned - 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15694707&form=6&db=m Marinobufagenin may mediate the impact of salty diets on left ventricular hypertrophy by disrupting the protective function of coronary microvascular endothelium. unassigned - 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15970491&form=6&db=m Cardenolide and bufadienolide ligands of the sodium pump. How they work together in NaCl sensitive hypertension. unassigned - 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16139690&form=6&db=m Endogenous cardiac glycosides: hormones using the sodium pump as signal transducer. causal interaction,unassigned 4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16178455&form=6&db=m [A novel hormone found in circulation--endogenous ouabain] causal interaction,unassigned 1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16247002&form=6&db=m The sodium pump and hypertension: a physiological role for the cardiac glycoside binding site of the Na,K-ATPase. therapeutic application,unassigned 1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16458353&form=6&db=m Marinobufagenin impairs first trimester cytotrophoblast differentiation. causal interaction,unassigned 4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17451677&form=6&db=m Na+/K+-ATPase alpha isoforms expression in stroke-prone spontaneously hypertensive rat heart ventricles: effect of salt loading and lacidipine treatment. causal interaction,unassigned 3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17535738&form=6&db=m Vascular endothelium as a target for endogenous ouabain: studies on the effect of ouabain on human endothelial cells. causal interaction,therapeutic application,unassigned 3,3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17581218&form=6&db=m Effect of maturation on renal Na+/K+-atpase and its susceptibility to nitric oxide-deficient hypertension in rats. ongoing research,unassigned 4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17913702&form=6&db=m Genetic determinants of emotionality and stress response in AcB/BcA recombinant congenic mice and in silico evidence of convergence with cardiovascular candidate genes. causal interaction,unassigned 3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17976639&form=6&db=m Transgenic overexpression of translationally controlled tumor protein induces systemic hypertension via repression of Na+,K+-ATPase. causal interaction,therapeutic application,unassigned 4,4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18282556&form=6&db=m Transactivation of epidermal growth factor receptor in vascular and renal systems in rats with experimental hyperleptinemia: role in leptin-induced hypertension. causal interaction,ongoing research,therapeutic application,unassigned 3,2,4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18304583&form=6&db=m Hypothetical mechanism of sodium pump regulation by estradiol under primary hypertension. causal interaction,therapeutic application,unassigned 3,1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19229192&form=6&db=m Endogenous cardiotonic steroids and differential patterns of sodium pump inhibition in NaCl-loaded salt-sensitive and normotensive rats. causal interaction,therapeutic application,unassigned 2,1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19909757&form=6&db=m Salt, Na+,K+-ATPase and hypertension. causal interaction,unassigned 2,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20009768&form=6&db=m Two-dimensional, sex-specific autosomal linkage scan of the number of sodium pump sites. therapeutic application,unassigned 1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20029541&form=6&db=m Dual effect of polyphenolic compounds on cardiac Na+/K+-ATPase during development and persistence of hypertension in rats. ongoing research,therapeutic application,unassigned 3,2,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21235787&form=6&db=m Main results of the ouabain and adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxin. ongoing research,therapeutic application,unassigned 2,1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21767529&form=6&db=m Oleic and linoleic acids are active principles in Nigella sativa and stabilize an E(2)P conformation of the Na,K-ATPase. Fatty acids differentially regulate cardiac glycoside interaction with the pump. causal interaction,therapeutic application,unassigned 1,2,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23459313&form=6&db=m Polymorphisms in migraine-associated gene, atp1a2, and ischemic stroke risk in a biracial population: the genetics of early onset stroke study. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,2,2,1 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23929930&form=6&db=m Dietary Sodium Restriction and Association with Urinary Marinobufagenin, Blood Pressure, and Aortic Stiffness. causal interaction,therapeutic application,unassigned 3,1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24136331&form=6&db=m Pulmonary arterial hypertension in familial hemiplegic migraine with ATP1A2 channelopathy. unassigned - 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24824258&form=6&db=m Effect of ouabain on the pathogenesis of hypertension in rats. ongoing research,unassigned 4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25279791&form=6&db=m Wistar rats resistant to the hypertensive effects of ouabain exhibit enhanced cardiac vagal activity and elevated plasma levels of calcitonin gene-related peptide. therapeutic application,unassigned 1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25479826&form=6&db=m Salt and gene expression: evidence for [Na(+)] i/[K (+)] i-mediated signaling pathways. causal interaction,unassigned 3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25736107&form=6&db=m [Preparation and characterization of polyclonal antibodies against rat sodium pump alpha 2 subunit M1-M2 extra membrane fragment]. therapeutic application,unassigned 1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26105942&form=6&db=m PP089. Analytical aspects of marinobufagenin and its applications in the diagnosis of preeclampsia. therapeutic application,unassigned 4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26198943&form=6&db=m [Effect of ouabain on intracellular Ca(2+) concentration in rat vascular smooth muscle cells in vitro]. therapeutic application,unassigned 1,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27884238&form=6&db=m The Pressure of Aging. causal interaction,unassigned 3,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28164755&form=6&db=m Regulation of Na+/K+-ATPase by Estradiol and IGF-1 in Cardio-Metabolic Diseases. causal interaction,diagnostic usage,therapeutic application,unassigned 3,3,4,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29853035&form=6&db=m Revealing of endogenous Marinobufagin by an ultra-specific and sensitive UHPLC-MS/MS assay in pregnant women. therapeutic application,unassigned 2,0 7.2.2.3 Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30849009&form=6&db=m Genetic and genomic evidence for an important role of the Na+/H+ exchanger 3 in blood pressure regulation and angiotensin II-induced hypertension. ongoing research,unassigned 2,0 7.2.2.3 Hypertension, Pregnancy-Induced http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1329936&form=6&db=m Pregnancy induced hypertension and sodium pump function in erythrocytes. diagnostic usage,ongoing research,therapeutic application,unassigned 4,2,1,0 7.2.2.3 Hypertension, Pregnancy-Induced http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1395072&form=6&db=m Endogenous digitalis-like factors. causal interaction,unassigned 1,0 7.2.2.3 Hypertension, Pregnancy-Induced http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2172375&form=6&db=m Sodium pump numbers and cation transport of lymphocytes in pregnancy-induced hypertension. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,2,4 7.2.2.3 Hypertension, Pregnancy-Induced http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9144326&form=6&db=m Modifications induced by plasma of gestational hypertensive women on the Na+/K+-ATPase obtained from human placenta. diagnostic usage,ongoing research,therapeutic application,unassigned 3,4,1,0 7.2.2.3 Hypertension, Pregnancy-Induced http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10463998&form=6&db=m Platelet sodium pump and sodium potassium cotransport activity in nonpregnant, normotensive, and hypertensive pregnant women. diagnostic usage,ongoing research,therapeutic application,unassigned 3,2,1,0 7.2.2.3 Hypertension, Pregnancy-Induced http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17498495&form=6&db=m [Ganoderma spores may regulate the levels of mitochondria-related molecular substances in hippocampus of young rats birthed by rats with gestational hypertension] diagnostic usage,ongoing research,unassigned 3,2,0 7.2.2.3 Hypertension, Renal http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8676814&form=6&db=m Dietary salt, intracellular ion homeostasis and hypertension secondary to early-stage kidney disease. causal interaction,unassigned 4,0 7.2.2.3 Hypertension, Renovascular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3034452&form=6&db=m Measurement by bioluminescence technique of erythrocyte membrane Na+,K+-ATPase activity in hypertensive patients. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,2,0 7.2.2.3 Hypertension, Renovascular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3964725&form=6&db=m Sodium pump activity in thymocytes of rats with Goldblatt hypertension. ongoing research,unassigned 1,0 7.2.2.3 Hypertension, Renovascular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7037634&form=6&db=m Sodium pump activity in arteries of rats with Goldblatt hypertension. causal interaction,ongoing research,unassigned 4,2,0 7.2.2.3 Hyperthyroidism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1324264&form=6&db=m Na+K+ATPase activity and ouabain binding sites in erythrocytes in hyperthyroidism before and after treatment. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,3,4 7.2.2.3 Hyperthyroidism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1333560&form=6&db=m Stimulation of the Na+,K(+)-ATPase activity of K562 human erythroleukemia cells by triiodothyronine. diagnostic usage,ongoing research,unassigned 3,3,0 7.2.2.3 Hyperthyroidism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1943442&form=6&db=m Induction of the ATP-dependent proteolytic system in guinea pig reticulocyte lysates by triiodothyronine. unassigned - 7.2.2.3 Hyperthyroidism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2023533&form=6&db=m Ouabain-binding sites of reticulocytes from guinea pigs treated with triiodothyronine. diagnostic usage,therapeutic application,unassigned 3,1,0 7.2.2.3 Hyperthyroidism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2168011&form=6&db=m Erythrocyte sodium fluxes, ouabain binding sites, and Na+,K(+)-ATPase activity in hyperthyroidism. diagnostic usage,ongoing research,unassigned 3,2,0 7.2.2.3 Hyperthyroidism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2370297&form=6&db=m The effect of hyperthyroidism on in vivo aging of erythrocyte ouabain-binding sites and intracellular sodium and potassium. causal interaction,therapeutic application,unassigned 3,1,0 7.2.2.3 Hyperthyroidism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2444369&form=6&db=m Erythrocyte ouabain binding in patients receiving thyroxine. causal interaction,unassigned 3,0 7.2.2.3 Hyperthyroidism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2477065&form=6&db=m The contribution of ATP turnover by the Na+/K+-ATPase to the rate of respiration of hepatocytes. Effects of thyroid status and fatty acids. unassigned - 7.2.2.3 Hyperthyroidism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2989030&form=6&db=m Effect of thyroid status on the development of the different molecular forms of Na+,K+-ATPase in rat brain. causal interaction,therapeutic application,unassigned 1,1,0 7.2.2.3 Hyperthyroidism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3028698&form=6&db=m Ion flux and Na+,K+-ATPase activity of erythrocytes and leucocytes in thyroid disease. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,1,1,1 7.2.2.3 Hyperthyroidism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4255533&form=6&db=m [A histochemical study of gastric adenosine triphosphatase, alkaline and acid phosphatase in experimental hypo- and hyperthyroidism] ongoing research,therapeutic application,unassigned 4,1,0 7.2.2.3 Hyperthyroidism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4260475&form=6&db=m [Adenosine triphosphatase activity of the liver and micro- and macroelement levels in the organism of white rats in experimental hyperthyroidism] ongoing research,unassigned 2,0 7.2.2.3 Hyperthyroidism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=5411480&form=6&db=m Abnormalities in the sodium pump of erythrocytes from patients with hyperthyroidism. causal interaction,diagnostic usage,ongoing research,unassigned 1,3,2,0 7.2.2.3 Hyperthyroidism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6090505&form=6&db=m Effects of thyroid hormone on sodium pump sites, sodium content, and contractile responses to cardiac glycosides in cultured chick ventricular cells. unassigned - 7.2.2.3 Hyperthyroidism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6284135&form=6&db=m No major thermogenic role for (Na+ + K+)-dependent adenosine triphosphatase apparent in hepatocytes from hyperthyroid rats. therapeutic application,unassigned 1,0 7.2.2.3 Hyperthyroidism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6284628&form=6&db=m Catecholamine and thyroid hormone influence on brown fat Na+, K+-ATPase activity and thermogenesis in the rat. diagnostic usage,ongoing research,unassigned 3,1,0 7.2.2.3 Hyperthyroidism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11437061&form=6&db=m Effects of oxidative stress on the erythrocyte Na+,K+ ATPase activity in female hyperthyroid patients. diagnostic usage,ongoing research,therapeutic application,unassigned 4,4,1,0 7.2.2.3 Hyperthyroidism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14078532&form=6&db=m [THE ADENOSINE TRIPHOSPHATASE ACTIVITY OF LEUKOCYTE HOMOGENATES IN HYPERTHYROIDISM.] diagnostic usage,unassigned 3,0 7.2.2.3 Hyperthyroidism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17618957&form=6&db=m Changes in acetylcholinesterase, Na+,K+-ATPase, and Mg2+-ATPase activities in the frontal cortex and the hippocampus of hyper- and hypothyroid adult rats. causal interaction,unassigned 2,0 7.2.2.3 Hypoglycemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21475241&form=6&db=m The role of spreading depression, spreading depolarization and spreading ischemia in neurological disease. therapeutic application,unassigned 2,0 7.2.2.3 Hypokalemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2580875&form=6&db=m Effects of digitalis on cell biochemistry: sodium pump inhibition. therapeutic application,unassigned 2,0 7.2.2.3 Hypokalemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3010693&form=6&db=m Epinephrine-induced hypokalemia: the role of beta adrenoceptors. therapeutic application,unassigned 1,0 7.2.2.3 Hypokalemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6206353&form=6&db=m The role of a humoral Na+,K+-ATPase inhibitor in regulating precapillary vessel tone. causal interaction,therapeutic application,unassigned 4,4,0 7.2.2.3 Hypokalemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6445796&form=6&db=m Effects of hypokalemia on the cardiotropic actions of digoxin in dogs. Correlation with inhibition of cardiac Na+,K+-adenosine triphosphatase. ongoing research,therapeutic application,unassigned 3,3,0 7.2.2.3 Hypokalemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7563097&form=6&db=m Significance of sodium pump isoforms in digitalis therapy. causal interaction,unassigned 1,0 7.2.2.3 Hypokalemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7943283&form=6&db=m Expression of Na(+)-K(+)-ATPase alpha- and beta-subunits along rat nephron: isoform specificity and response to hypokalemia. unassigned - 7.2.2.3 Hypokalemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8250319&form=6&db=m Hypokalemia and anesthetic implications. causal interaction,diagnostic usage,therapeutic application,unassigned 3,1,2,0 7.2.2.3 Hypokalemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17275585&form=6&db=m Distal renal tubular acidosis and the potassium enigma. unassigned - 7.2.2.3 Hypoparathyroidism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15533723&form=6&db=m X-linked hypoparathyroidism region on Xq27 is evolutionarily conserved with regions on 3q26 and 13q34 and contains a novel P-type ATPase. causal interaction,unassigned 2,0 7.2.2.3 Hypotension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31450834&form=6&db=m Modulation of Cardiovascular Function in Primary Hypertension in Rat by SKA-31, an Activator of KCa2.x and KCa3.1 Channels. therapeutic application,unassigned 1,0 7.2.2.3 Hypothyroidism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2989030&form=6&db=m Effect of thyroid status on the development of the different molecular forms of Na+,K+-ATPase in rat brain. causal interaction,therapeutic application,unassigned 1,1,0 7.2.2.3 Hypothyroidism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3028698&form=6&db=m Ion flux and Na+,K+-ATPase activity of erythrocytes and leucocytes in thyroid disease. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,1,1,1 7.2.2.3 Hypothyroidism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28256112&form=6&db=m The Effects of Altered Membrane Cholesterol Levels on Sodium Pump Activity in Subclinical Hypothyroidism. diagnostic usage,ongoing research,unassigned 3,3,0 7.2.2.3 Hypothyroidism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32302609&form=6&db=m Modulation of glutamate levels and Na+,K+-ATPase activity contributes to the chrysin memory recovery in hypothyroidism mice. diagnostic usage,ongoing research,therapeutic application,unassigned 1,2,1,0 7.2.2.3 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2555121&form=6&db=m Changes in Na,K-ATPase, sodium ion, and glucose transport in isolated enterocytes in an experimental model of malabsorption. diagnostic usage,unassigned 1,0 7.2.2.3 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2824232&form=6&db=m Schistosoma mansoni: fine structural localization of tegumental adenosine triphosphatases. diagnostic usage,ongoing research,unassigned 3,2,0 7.2.2.3 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4276083&form=6&db=m Adenosine triphosphatase activity associated with bovine erythrocyte membranes during infection with Anaplasma marginale. unassigned - 7.2.2.3 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7687413&form=6&db=m Altered expression of sodium pump isoforms in the inflamed intestine of Trichinella spiralis-infected rats. causal interaction,diagnostic usage,ongoing research,unassigned 3,4,4,0 7.2.2.3 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8979423&form=6&db=m Thyroid status and adenosine triphosphatase activity in experimental Trypanosoma congolense infection in rabbits. diagnostic usage,ongoing research,therapeutic application,unassigned 3,2,1,0 7.2.2.3 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10467028&form=6&db=m Localization of H(+)-ATPases in soybean root nodules. ongoing research,unassigned 2,0 7.2.2.3 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11549759&form=6&db=m PDE1 encodes a P-type ATPase involved in appressorium-mediated plant infection by the rice blast fungus Magnaporthe grisea. therapeutic application,unassigned 1,0 7.2.2.3 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24139291&form=6&db=m Effects of Cryptocaryon irritans infection on the survival, feeding, respiratory rate and ionic regulation of the marbled rockfish Sebastiscus marmoratus. causal interaction,diagnostic usage,unassigned 1,2,0 7.2.2.3 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29516859&form=6&db=m Stress effects of amyloodiniosis in gilthead sea bream Sparus aurata. unassigned - 7.2.2.3 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29962265&form=6&db=m Induction of a Na+/K+-ATPase-dependent form of autophagy triggers preferential cell death of human immunodeficiency virus type-1-infected macrophages. causal interaction,ongoing research,unassigned 1,1,0 7.2.2.3 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30728284&form=6&db=m The Vacuolar Ca2+ ATPase Pump Pmc1p Is Required for Candida albicans Pathogenesis. causal interaction,unassigned 1,0 7.2.2.3 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31142734&form=6&db=m Selective cell death of latently HIV-infected CD4+ T cells mediated by autosis inducing nanopeptides. causal interaction,unassigned 1,0 7.2.2.3 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31871089&form=6&db=m Screening of Natural Extracts for Inhibitors against Japanese Encephalitis Virus Infection. causal interaction,therapeutic application,unassigned 4,4,0 7.2.2.3 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31926988&form=6&db=m The antidiarrhoeal evaluation of Psidium guajava L. against enteropathogenic Escherichia coli induced infectious diarrhoea. diagnostic usage,unassigned 1,0 7.2.2.3 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33254543&form=6&db=m Hypotheses about sub-optimal hydration in the weeks before coronavirus disease (COVID-19) as a risk factor for dying from COVID-19. causal interaction,unassigned 3,0 7.2.2.3 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34091227&form=6&db=m Effects of glycyrrhizin on the growth cycle and ATPase activity of PRRSV-2-infected MARC-145 cells. causal interaction,unassigned 2,0 7.2.2.3 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=100134966&form=6&db=m Multiplex PCR for the diagnosis of red sea bream iridoviruses isolated in Korea. diagnostic usage,unassigned 3,0 7.2.2.3 Influenza, Human http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23876457&form=6&db=m Glycolytic control of vacuolar-type ATPase activity: A mechanism to regulate influenza viral infection. causal interaction,diagnostic usage,unassigned 4,1,0 7.2.2.3 Influenza, Human http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24239327&form=6&db=m Pathogenesis of influenza-induced acute respiratory distress syndrome. ongoing research,unassigned 4,0 7.2.2.3 Influenza, Human http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33935717&form=6&db=m Na+/K+-ATPase as a Target of Cardiac Glycosides for the Treatment of SARS-CoV-2 Infection. causal interaction,therapeutic application,unassigned 3,4,0 7.2.2.3 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2448070&form=6&db=m The effect of oral glucose on the leucocyte sodium pump in normal and obese subjects. causal interaction,unassigned 2,0 7.2.2.3 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2562127&form=6&db=m Insulin sensitivity of rat muscle sodium pump. ongoing research,unassigned 4,0 7.2.2.3 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8929644&form=6&db=m Association of sick sinus syndrome with hyperinsulinemia and insulin resistance in patients with non-insulin-dependent diabetes mellitus: report of four cases. causal interaction,unassigned 3,0 7.2.2.3 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11133519&form=6&db=m Short-term K(+) deprivation provokes insulin resistance of cellular K(+) uptake revealed with the K(+) clamp. therapeutic application,unassigned 1,0 7.2.2.3 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16139689&form=6&db=m Role of muscle in regulating extracellular [K+]. therapeutic application,unassigned 1,0 7.2.2.3 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19366873&form=6&db=m Altered expression and insulin-induced trafficking of Na+, K+-ATPase in rat skeletal muscle: effects of high fat diet and exercise. ongoing research,unassigned 2,0 7.2.2.3 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24043574&form=6&db=m Expression and Cellular Distribution of Glucose Transporters and Alpha Subunits of Na+/K+-ATPase in the Heart of Fructose-fed Female Rats: The Role of Estradiol. ongoing research,unassigned 3,0 7.2.2.3 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32483445&form=6&db=m DR-region of Na+/K+-ATPase is a target to ameliorate hepatic insulin resistance in obese diabetic mice. therapeutic application,unassigned 1,0 7.2.2.3 Intellectual Disability http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16437583&form=6&db=m Severe episodic neurological deficits and permanent mental retardation in a child with a novel FHM2 ATP1A2 mutation. causal interaction,therapeutic application,unassigned 4,1,0 7.2.2.3 Intellectual Disability http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30760526&form=6&db=m Asparagine-905 of the mammalian phospholipid flippase ATP8A2 is essential for lipid substrate-induced activation of ATP8A2 dephosphorylation. causal interaction,therapeutic application,unassigned 1,1,0 7.2.2.3 Intellectual Disability http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31766058&form=6&db=m Early Treatment in Acute Severe Encephalopathy Caused by ATP1A2 Mutation of Familial Hemiplegic Migraine Type 2: Case Report and Literature Review. causal interaction,therapeutic application,unassigned 4,4,0 7.2.2.3 Intellectual Disability http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34384358&form=6&db=m Functional correlation of ATP1A2 mutations with phenotypic spectrum: from pure hemiplegic migraine to its variant forms. causal interaction,unassigned 4,0 7.2.2.3 Intermittent Claudication http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=579309&form=6&db=m Histochemical changes in striated muscle in patients with intermittent claudication. diagnostic usage,ongoing research,therapeutic application,unassigned 2,4,1,0 7.2.2.3 Intestinal Volvulus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10643902&form=6&db=m Ivermectin: concentration-dependent effects on adenosine triphosphatases in adult worms of Onchocerca volvulus. ongoing research,unassigned 4,0 7.2.2.3 Intraabdominal Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2932304&form=6&db=m Increased hepatic microsomal adenosine triphosphatase activity secondary to intra-abdominal infection. unassigned - 7.2.2.3 Intracranial Embolism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9767164&form=6&db=m Microsphere embolism-induced changes in noradrenaline uptake of the cerebral cortex in rats. causal interaction,ongoing research,unassigned 1,2,0 7.2.2.3 Iron Deficiencies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2173894&form=6&db=m Changes in the cochlear iron enzymes and adenosine triphosphatase in experimental iron deficiency. causal interaction,ongoing research,unassigned 3,2,0 7.2.2.3 Ischemic Stroke http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17439716&form=6&db=m Magnesium lithospermate B possesses inhibitory activity on Na+,K+-ATPase and neuroprotective effects against ischemic stroke. ongoing research,therapeutic application,unassigned 2,2,0 7.2.2.3 Ischemic Stroke http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23459313&form=6&db=m Polymorphisms in migraine-associated gene, atp1a2, and ischemic stroke risk in a biracial population: the genetics of early onset stroke study. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,2,2,1 7.2.2.3 Kidney Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1336078&form=6&db=m Maximum binding of ouabain to erythrocytes in relation to a family history of essential hypertension, sodium balance and body weight in normotensive children. diagnostic usage,ongoing research,unassigned 2,2,0 7.2.2.3 Kidney Failure, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1661399&form=6&db=m [Effect of hemodialysis on the erythrocyte sodium, potassium adenosine triphosphatase activity in children with chronic renal failure] diagnostic usage,unassigned 1,0 7.2.2.3 Kidney Failure, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2074649&form=6&db=m Effects of acute and chronic uremia on active cation transport in rat myocardium. causal interaction,ongoing research,therapeutic application,unassigned 3,4,1,0 7.2.2.3 Kidney Failure, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2144869&form=6&db=m Red blood cell calcium level in chronic renal failure: effect of continuous ambulatory peritoneal dialysis. causal interaction,diagnostic usage,therapeutic application,unassigned 1,3,1,0 7.2.2.3 Kidney Failure, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2824372&form=6&db=m Endogenous cardiac glycosidelike compounds. causal interaction,unassigned 3,0 7.2.2.3 Kidney Failure, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2832446&form=6&db=m Abnormal cation transport in uremia. Mechanisms in adipocytes and skeletal muscle from uremic rats. causal interaction,ongoing research,therapeutic application,unassigned 1,2,1,0 7.2.2.3 Kidney Failure, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6216810&form=6&db=m Biochemical abnormalities of platelets in renal failure. Evidence for decreased platelet serotonin, adenosine diphosphate and Mg-dependent adenosine triphosphatase. causal interaction,diagnostic usage,ongoing research,unassigned 3,3,2,0 7.2.2.3 Kidney Failure, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6255727&form=6&db=m Inhibition of Na+,K+-stimulated ATPase in the cochlea of the guinea pig. A potential cause of disturbed inner ear function in terminal renal failure. causal interaction,ongoing research,therapeutic application,unassigned 1,2,2,0 7.2.2.3 Kidney Failure, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6731036&form=6&db=m Potassium in skeletal muscle in untreated primary hypertension and in chronic renal failure, studied by X-ray fluorescence technique. causal interaction,unassigned 4,0 7.2.2.3 Kidney Failure, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8821826&form=6&db=m Specificity of the volume-sensitive sodium pump inhibitor isolated from human peritoneal dialysate in chronic renal failure. ongoing research,therapeutic application,unassigned 4,1,0 7.2.2.3 Kidney Failure, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8834705&form=6&db=m Reversal of sodium pump inhibitor induced vascular smooth muscle contraction with digibind. Stoichiometry and its implications. causal interaction,ongoing research,therapeutic application,unassigned 3,1,4,0 7.2.2.3 Kidney Failure, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16458353&form=6&db=m Marinobufagenin impairs first trimester cytotrophoblast differentiation. causal interaction,unassigned 4,0 7.2.2.3 Kidney Failure, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29679284&form=6&db=m Garlic (Allium sativum) exhibits a cardioprotective effect in experimental chronic renal failure rat model by reducing oxidative stress and controlling cardiac Na+/K+-ATPase activity and Ca2+ levels. unassigned - 7.2.2.3 Kidney Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22204337&form=6&db=m Cardiotonic Steroids-Mediated Targeting of the Na(+)/K(+)-ATPase to Combat Chemoresistant Cancers. causal interaction,unassigned 2,0 7.2.2.3 Kwashiorkor http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=147623&form=6&db=m Erythrocyte membrane Na+ and K+ activated adenosine triphosphatase in protein-calorie malnutrition. diagnostic usage,ongoing research,unassigned 1,2,0 7.2.2.3 Lecithin Cholesterol Acyltransferase Deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6246569&form=6&db=m Study of erythrocytes in a hereditary hemolytic syndrome (HHS): comparison with erythrocytes in lecithin:cholesterol acyltransferase (LCAT) deficiency. causal interaction,unassigned 1,0 7.2.2.3 Leigh Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7668837&form=6&db=m A novel mitochondrial ATPase 6 point mutation in familial bilateral striatal necrosis. unassigned - 7.2.2.3 Leigh Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11198506&form=6&db=m Mitochondrial DNA point mutation T9176C in Leigh syndrome. causal interaction,unassigned 4,0 7.2.2.3 Leigh Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12597054&form=6&db=m Mitochondrial disorders. unassigned - 7.2.2.3 Leiomyosarcoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31351063&form=6&db=m Copper ions are novel therapeutic agents for uterine leiomyosarcoma. diagnostic usage,ongoing research,therapeutic application,unassigned 3,3,4,0 7.2.2.3 Lesch-Nyhan Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15829228&form=6&db=m Effect of hypoxanthine on Na+,K+-ATPase activity and some parameters of oxidative stress in rat striatum. ongoing research,unassigned 4,0 7.2.2.3 Leukemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2544628&form=6&db=m Expression of multiple Na+,K+-adenosine triphosphatase isoform genes in human hematopoietic cells. Behavior of the novel A3 isoform during induced maturation of HL60 cells. diagnostic usage,ongoing research,unassigned 3,4,0 7.2.2.3 Leukemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3342461&form=6&db=m Membrane transport changes in an adriamycin-resistant murine leukemia cell line and in its sensitive parental cell line. diagnostic usage,ongoing research,unassigned 3,4,0 7.2.2.3 Leukemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4226375&form=6&db=m Electron microscopic observations on the adenosine triphosphatase activity of a murine (Rauscher) and a canine leukemia virus. ongoing research,therapeutic application,unassigned 3,1,0 7.2.2.3 Leukemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4243024&form=6&db=m [Demonstration of adenosine triphosphatase in blood smears of acute leukemias and comparison with other enzyme-cytochemical reactions] unassigned - 7.2.2.3 Leukemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6288289&form=6&db=m Leucocyte sodium-potassium adenosine triphosphatase and leukemia. unassigned - 7.2.2.3 Leukemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6860168&form=6&db=m [Stereological characteristics and enzymatic activity of myocardial capillaries in different variants of pathology and death (data from immediate autopsies)] diagnostic usage,ongoing research,unassigned 3,3,0 7.2.2.3 Leukemia, Erythroblastic, Acute http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=214640&form=6&db=m The program of Friend cell erythroid differentiation: early changes in Na+/K+ ATPase function. causal interaction,therapeutic application,unassigned 2,4,0 7.2.2.3 Leukemia, Erythroblastic, Acute http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6150038&form=6&db=m Characterization of a Ca2+-stimulated Mg2+-dependent adenosine triphosphatase in Friend murine erythroleukemia cell plasma membranes. ongoing research,unassigned 3,0 7.2.2.3 Leukemia, Lymphoid http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18088458&form=6&db=m [Effects of ouabain at low concentrations on growth of leukemia cells] ongoing research,unassigned 4,0 7.2.2.3 Leukemia, Megakaryoblastic, Acute http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18088458&form=6&db=m [Effects of ouabain at low concentrations on growth of leukemia cells] ongoing research,unassigned 4,0 7.2.2.3 Leukemia, Myeloid, Acute http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33790022&form=6&db=m Targeting acute myeloid leukemia dependency on VCP-mediated DNA repair through a selective second-generation small-molecule inhibitor. causal interaction,therapeutic application,unassigned 2,1,0 7.2.2.3 Lichen Planus, Oral http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21465009&form=6&db=m Assessment of langerhans cells in oral lichen planus by ATPase histochemistry: a clinicopathologic correlation. diagnostic usage,ongoing research,unassigned 1,3,0 7.2.2.3 Liver Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=155541&form=6&db=m Evidence that adenosine triphosphatase is one of the mitochondrial antigens of autoimmune liver disease [proceedings] causal interaction,unassigned 3,0 7.2.2.3 Liver Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2953084&form=6&db=m [Comparative characteristics of adenosine triphosphatase activity in the erythrocytes of patients with acute and chronic liver diseases, chronic cholecystitis and in HBs antigen carriers] causal interaction,diagnostic usage,ongoing research,unassigned 4,4,4,0 7.2.2.3 Liver Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4275142&form=6&db=m [Adenosine triphosphatase activity of erythrocytes in liver diseases in children] ongoing research,unassigned 2,0 7.2.2.3 Liver Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6319261&form=6&db=m Inhibition of rat brain Na+,K+-ATPase activity by serum from patients with fulminant hepatic failure. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,3,0 7.2.2.3 Liver Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12880872&form=6&db=m FIC1, a P-type ATPase linked to cholestatic liver disease, has homologues (ATP8B2 and ATP8B3) expressed throughout the body. causal interaction,ongoing research,unassigned 1,2,0 7.2.2.3 Liver Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33437900&form=6&db=m Assessment of Adenosine Triphosphatase Phospholipid Transporting 8B1 (ATP8B1) Function in Patients With Cholestasis With ATP8B1 Deficiency by Using Peripheral Blood Monocyte-Derived Macrophages. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,2,2,1 7.2.2.3 Liver Failure, Acute http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=213231&form=6&db=m A study in vitro of the sodium pump in fulminant hepatic failure. ongoing research,unassigned 4,0 7.2.2.3 Liver Failure, Acute http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6319261&form=6&db=m Inhibition of rat brain Na+,K+-ATPase activity by serum from patients with fulminant hepatic failure. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,3,0 7.2.2.3 Liver Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32731591&form=6&db=m Oxidative Stress and Apoptotic Responses Elicited by Nostoc-Synthesized Silver Nanoparticles against Different Cancer Cell Lines. ongoing research,therapeutic application,unassigned 4,1,0 7.2.2.3 Liver Neoplasms, Experimental http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=200347&form=6&db=m Membranous effects on adenosine triphosphatase activities of mitochondria from rat liver and Morris hepatoma 3924A. ongoing research,unassigned 4,0 7.2.2.3 Lung Injury http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18439324&form=6&db=m Improving survival by increasing lung edema clearance: is airspace delivery of dopamine a solution? causal interaction,therapeutic application,unassigned 3,2,0 7.2.2.3 Lung Injury http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22310113&form=6&db=m Electroporation-mediated in vivo gene delivery of the Na+/K+-ATPase pump reduced lung injury in a mouse model of lung contusion. ongoing research,therapeutic application,unassigned 2,2,0 7.2.2.3 Lung Injury http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27078880&form=6&db=m Omega-9 Oleic Acid Induces Fatty Acid Oxidation and Decreases Organ Dysfunction and Mortality in Experimental Sepsis. causal interaction,unassigned 2,0 7.2.2.3 Lung Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7645956&form=6&db=m Role of sodium pump systems to determine sensitivity to mitomycin C in non-small cell lung cancer cell lines. ongoing research,therapeutic application,unassigned 4,1,0 7.2.2.3 Lung Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17471453&form=6&db=m The alpha1 subunit of the sodium pump could represent a novel target to combat non-small cell lung cancers. causal interaction,ongoing research,therapeutic application,unassigned 3,1,3,0 7.2.2.3 Lung Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18636185&form=6&db=m Expression of copper-transporting P-type adenosine triphosphatase (ATP7B) correlates with cisplatin resistance in human non-small cell lung cancer xenografts. causal interaction,diagnostic usage,ongoing research,therapeutic application 2,1,3,3 7.2.2.3 Lung Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22304828&form=6&db=m Copper-transporting P-type adenosine triphosphatase (ATP7A) is associated with platinum-resistance in non-small cell lung cancer (NSCLC). causal interaction,diagnostic usage,unassigned 2,1,0 7.2.2.3 Lung Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23412992&form=6&db=m Cardiotonic Steroids-Mediated Na+/K+-ATPase Targeting Could Circumvent Various Chemoresistance Pathways. causal interaction,diagnostic usage,therapeutic application,unassigned 4,3,1,0 7.2.2.3 Lung Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24038379&form=6&db=m MiR-495 enhances the sensitivity of non-small cell lung cancer cells to platinum by modulation of copper-transporting P-type adenosine triphosphatase A (ATP7A). causal interaction,ongoing research,therapeutic application,unassigned 2,2,2,0 7.2.2.3 Lung Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26033426&form=6&db=m Clinical outcome of cisplatin-based chemotherapy is associated with the polymorphisms of GSTP1 and XRCC1 in advanced non-small cell lung cancer patients. causal interaction,diagnostic usage,therapeutic application,unassigned 4,4,3,0 7.2.2.3 Lung Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29970705&form=6&db=m Evaluation of the relationship of erythrocyte membrane Na+/K+-ATPase enzyme activity and tumor response to chemoradiotherapy in patients diagnosed with locally advanced nonsmall cell lung cancer and glioblastoma multiforme. diagnostic usage,ongoing research,therapeutic application,unassigned 4,1,1,0 7.2.2.3 Lung Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31891085&form=6&db=m New 99mTc-Labeled Digitoxigenin Derivative for Cancer Cell Identification. ongoing research,unassigned 4,0 7.2.2.3 Lung Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31953129&form=6&db=m Cytotoxic and non-cytotoxic cardiac glycosides isolated from the combined flowers, leaves, and twigs of Streblus asper. therapeutic application,unassigned 2,0 7.2.2.3 Lung Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33459980&form=6&db=m Cytotoxicity of glucoevatromonoside alone and in combination with chemotherapy drugs and their effects on Na+,K+-ATPase and ion channels on lung cancer cells. ongoing research,therapeutic application,unassigned 4,4,0 7.2.2.3 Lymphoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=160756&form=6&db=m Mg2+-dependent adenosine triphosphatase as an enzyme histochemical marker for the lymphomas of B-cell origin. diagnostic usage,ongoing research,unassigned 4,2,0 7.2.2.3 Lymphoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2454089&form=6&db=m Malignant lymphomas in the acquired immunodeficiency syndrome. Additional evidence for a B-cell origin. diagnostic usage,therapeutic application,unassigned 3,1,0 7.2.2.3 Lymphoma, B-Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25936661&form=6&db=m Activation of novel estrogen receptor GPER results in inhibition of cardiocyte apoptosis and cardioprotection. diagnostic usage,ongoing research,unassigned 4,2,0 7.2.2.3 Lymphoma, B-Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32731591&form=6&db=m Oxidative Stress and Apoptotic Responses Elicited by Nostoc-Synthesized Silver Nanoparticles against Different Cancer Cell Lines. ongoing research,therapeutic application,unassigned 4,1,0 7.2.2.3 Lymphoma, Non-Hodgkin http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=145325&form=6&db=m An enzyme histochemical study of non-Hodgkin's lymphoma and allied disease. diagnostic usage,ongoing research,unassigned 3,3,0 7.2.2.3 Lymphoma, Non-Hodgkin http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6152086&form=6&db=m [Circadian rhythm of adenosine triphosphatase activity and 32P content in Pliss lymphosarcoma] unassigned - 7.2.2.3 Malaria http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17030505&form=6&db=m PbGCbeta is essential for Plasmodium ookinete motility to invade midgut cell and for successful completion of parasite life cycle in mosquitoes. ongoing research,unassigned 2,0 7.2.2.3 Malnutrition http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=111257&form=6&db=m Oedema in protein energy malnutrition: the role of the sodium pump. unassigned - 7.2.2.3 Malnutrition http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=870140&form=6&db=m Death during recovery from severe malnutrition and its possible relationship to sodium pump activity in the leucocyte. ongoing research,unassigned 3,0 7.2.2.3 Malnutrition http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2167221&form=6&db=m Reduction in vitro of red cell glutathione reproduces defects of cellular sodium transport seen in oedematous malnutrition. causal interaction,unassigned 1,0 7.2.2.3 Malnutrition http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4252414&form=6&db=m [Subcellular distribution of the activity of the adenosine triphosphatase system during postnatal maturation of rat brain: influence of malnutrition] diagnostic usage,ongoing research,unassigned 1,4,0 7.2.2.3 Malnutrition http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6255382&form=6&db=m Na+,K+-ATPase in developing rat brain during undernutrition. diagnostic usage,ongoing research,unassigned 2,4,0 7.2.2.3 Mania http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9271006&form=6&db=m Lithium prevents ouabain-induced behavioral changes. Toward an animal model for manic depression. causal interaction,unassigned 2,0 7.2.2.3 Mania http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10467969&form=6&db=m Endogenous digoxin-like immunoreactive factor (DLIF) serum concentrations are decreased in manic bipolar patients compared to normal controls. causal interaction,unassigned 3,0 7.2.2.3 Mania http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12180275&form=6&db=m Evaluation of neuroprotection by lithium and valproic acid against ouabain-induced cell damage. causal interaction,therapeutic application,unassigned 3,3,0 7.2.2.3 Mania http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14525557&form=6&db=m Intracerebroventricular administration of ouabain as a model of mania in rats. ongoing research,therapeutic application,unassigned 1,3,0 7.2.2.3 Mania http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16815616&form=6&db=m Efficacy of olanzapine and haloperidol in an animal model of mania. causal interaction,ongoing research,therapeutic application,unassigned 3,4,4,0 7.2.2.3 Mania http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17720496&form=6&db=m Mimicking human bipolar ion dysregulation models mania in rats. ongoing research,unassigned 4,0 7.2.2.3 Mania http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19255820&form=6&db=m Na+,K+-ATPase activity in an animal model of mania. ongoing research,unassigned 4,0 7.2.2.3 Mania http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19524007&form=6&db=m Effect of ouabain on sodium pump alpha-isoform expression in an animal model of mania. causal interaction,ongoing research,therapeutic application,unassigned 4,3,4,0 7.2.2.3 Mania http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27267245&form=6&db=m Cognitive flexibility impairment and reduced frontal cortex BDNF expression in the ouabain model of mania. therapeutic application,unassigned 3,0 7.2.2.3 Massive Hepatic Necrosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10461683&form=6&db=m Preventive effect of zinc compounds, polaprezinc and zinc acetate against the onset of hepatitis in Long-Evans Cinnamon rat. causal interaction,unassigned 3,0 7.2.2.3 Mastitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22535401&form=6&db=m Polymorphisms of the ATP1A1 gene associated with mastitis in dairy cattle. causal interaction,unassigned 1,0 7.2.2.3 Mastocytoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6264062&form=6&db=m Effect of D-glucosamine on growth and several functions of cultured mastocytoma P-815 cells. unassigned - 7.2.2.3 Medulloblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21498719&form=6&db=m Immunohistochemical analyses of alpha1 and alpha3 Na+/K+-ATPase subunit expression in medulloblastomas. ongoing research,unassigned 1,0 7.2.2.3 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15563845&form=6&db=m Identification and cloning of genes displaying elevated expression as a consequence of metastatic progression in human melanoma cells by rapid subtraction hybridization. unassigned - 7.2.2.3 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19243476&form=6&db=m The Sodium Pump alpha1 Subunit: a Disease Progression-Related Target for Metastatic Melanoma Treatment. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,4,4 7.2.2.3 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21135099&form=6&db=m Activity of BK(Ca) channel is modulated by membrane cholesterol content and association with Na+/K+-ATPase in human melanoma IGR39 cells. ongoing research,unassigned 1,0 7.2.2.3 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22204337&form=6&db=m Cardiotonic Steroids-Mediated Targeting of the Na(+)/K(+)-ATPase to Combat Chemoresistant Cancers. causal interaction,unassigned 2,0 7.2.2.3 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23412992&form=6&db=m Cardiotonic Steroids-Mediated Na+/K+-ATPase Targeting Could Circumvent Various Chemoresistance Pathways. causal interaction,diagnostic usage,therapeutic application,unassigned 4,3,1,0 7.2.2.3 Memory Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31476364&form=6&db=m The neuroprotective role of melatonin in a gestational hypermethioninemia model. causal interaction,unassigned 2,0 7.2.2.3 Memory Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32302609&form=6&db=m Modulation of glutamate levels and Na+,K+-ATPase activity contributes to the chrysin memory recovery in hypothyroidism mice. diagnostic usage,ongoing research,therapeutic application,unassigned 1,2,1,0 7.2.2.3 Memory Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33755857&form=6&db=m Multitarget Effect of 2-(4-(Methylthio)phenyl)-3-(3-(piperidin-1-yl)propyl)thiazolidin-4-one in a Scopolamine-Induced Amnesic Rat Model. causal interaction,unassigned 2,0 7.2.2.3 Meniere Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6293330&form=6&db=m Possible functional roles of Na+,K+-ATPase in the inner ear and their relevance to Ménière's disease. diagnostic usage,ongoing research,unassigned 3,1,0 7.2.2.3 Meningitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25286995&form=6&db=m Increased Na+,K+-ATPase activity in the rat brain after meningitis induction by Streptococcus pneumoniae. unassigned - 7.2.2.3 Menkes Kinky Hair Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7552582&form=6&db=m Wilson's disease: a new gene and an animal model for an old disease. diagnostic usage,unassigned 4,0 7.2.2.3 Menkes Kinky Hair Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7607665&form=6&db=m Characterization of the exon structure of the Menkes disease gene using vectorette PCR. unassigned - 7.2.2.3 Menkes Kinky Hair Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7785328&form=6&db=m Sequence, mapping and disruption of CCC2, a gene that cross-complements the Ca(2+)-sensitive phenotype of csg1 mutants and encodes a P-type ATPase belonging to the Cu(2+)-ATPase subfamily. causal interaction,unassigned 1,0 7.2.2.3 Menkes Kinky Hair Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8091505&form=6&db=m Wilson disease and Menkes disease: new handles on heavy-metal transport. unassigned - 7.2.2.3 Menkes Kinky Hair Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9215672&form=6&db=m Molecular basis of the brindled mouse mutant (Mo(br)): a murine model of Menkes disease. causal interaction,unassigned 3,0 7.2.2.3 Menkes Kinky Hair Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9452509&form=6&db=m Functional expression of the menkes disease protein reveals common biochemical mechanisms among the copper-transporting P-type ATPases. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,1,3,1 7.2.2.3 Menkes Kinky Hair Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10790207&form=6&db=m Mutational analysis of ATP7B and genotype-phenotype correlation in Japanese with Wilson's disease. diagnostic usage,unassigned 2,0 7.2.2.3 Menkes Kinky Hair Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12594858&form=6&db=m Genomic organization of ATOX1, a human copper chaperone. causal interaction,diagnostic usage,unassigned 3,2,0 7.2.2.3 Menkes Kinky Hair Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16603790&form=6&db=m Copper homeostasis in the CNS: a novel link between the NMDA receptor and copper homeostasis in the hippocampus. causal interaction,unassigned 3,0 7.2.2.3 Menkes Kinky Hair Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17215139&form=6&db=m ATP7A (Menkes protein) functions in axonal targeting and synaptogenesis. causal interaction,unassigned 4,0 7.2.2.3 Menkes Kinky Hair Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17336116&form=6&db=m Safety of intracerebroventricular copper histidine in adult rats. unassigned - 7.2.2.3 Menkes Kinky Hair Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18356322&form=6&db=m ATP7A transgenic and nontransgenic mice are resistant to high copper exposure. unassigned - 7.2.2.3 Menkes Kinky Hair Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21878905&form=6&db=m ATP7A gene addition to the choroid plexus results in long-term rescue of the lethal copper transport defect in a Menkes disease mouse model. causal interaction,unassigned 4,0 7.2.2.3 Menkes Kinky Hair Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23224983&form=6&db=m L-Threo-Dihydroxyphenylserine corrects neurochemical abnormalities in a menkes disease mouse model. causal interaction,unassigned 4,0 7.2.2.3 Menkes Kinky Hair Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25574028&form=6&db=m Direct interactions of adaptor protein complexes 1 and 2 with the copper transporter ATP7A mediate its anterograde and retrograde trafficking. causal interaction,unassigned 4,0 7.2.2.3 Menkes Kinky Hair Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27455805&form=6&db=m [Copper metabolism and genetic disorders]. unassigned - 7.2.2.3 Menkes Kinky Hair Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28451781&form=6&db=m 13 novel putative mutations in ATP7A found in a cohort of 25 Italian families. causal interaction,unassigned 2,0 7.2.2.3 Menkes Kinky Hair Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31396659&form=6&db=m Adipocyte-specific disruption of ATPase copper transporting ? in mice accelerates lipoatrophy. therapeutic application,unassigned 1,0 7.2.2.3 Menkes Kinky Hair Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34430447&form=6&db=m Menkes disease diagnosed by a novel ATP7A frameshift mutation in a patient with infantile spasms-a case report. causal interaction,unassigned 4,0 7.2.2.3 Mesothelioma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2436780&form=6&db=m Immunohistochemical and histochemical markers of primary lung cancer, lung metastases, and pleural mesotheliomas. diagnostic usage,ongoing research,therapeutic application,unassigned 3,2,1,0 7.2.2.3 Metabolic Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17977697&form=6&db=m Regulation of the Na,K-ATPase: Special implications for cardiovascular complications of metabolic syndrome. causal interaction,therapeutic application,unassigned 1,1,0 7.2.2.3 Metabolic Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18282556&form=6&db=m Transactivation of epidermal growth factor receptor in vascular and renal systems in rats with experimental hyperleptinemia: role in leptin-induced hypertension. causal interaction,ongoing research,therapeutic application,unassigned 3,2,4,0 7.2.2.3 Metabolic Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30731468&form=6&db=m Decreased Na+/K+-ATPase Activity and Altered Susceptibility to Peroxidation and Lipid Composition in the Erythrocytes of Metabolic Syndrome Patients with Coronary Artery Disease. diagnostic usage,ongoing research,unassigned 1,2,0 7.2.2.3 Microcephaly http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30690204&form=6&db=m Biallelic loss of function variants in ATP1A2 cause hydrops fetalis, microcephaly, arthrogryposis and extensive cortical malformations. causal interaction,unassigned 1,0 7.2.2.3 Microcephaly http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33880529&form=6&db=m ATP1A2- and ATP1A3-associated early profound epileptic encephalopathy and polymicrogyria. causal interaction,therapeutic application,unassigned 4,1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12119109&form=6&db=m Physical mapping and characterization of the human Na,K-ATPase isoform, ATP1A4. ongoing research,unassigned 1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12539047&form=6&db=m Haploinsufficiency of ATP1A2 encoding the Na+/K+ pump alpha2 subunit associated with familial hemiplegic migraine type 2. causal interaction,therapeutic application,unassigned 1,1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12915447&form=6&db=m Significant linkage to migraine with aura on chromosome 11q24. causal interaction,unassigned 1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12953268&form=6&db=m Novel mutations in the Na+, K+-ATPase pump gene ATP1A2 associated with familial hemiplegic migraine and benign familial infantile convulsions. causal interaction,unassigned 3,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14624354&form=6&db=m Update on the genetics of migraine. causal interaction,therapeutic application,unassigned 3,1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14636773&form=6&db=m New discoveries about the second gene for familial hemiplegic migraine, ATP1A2. unassigned - 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15021241&form=6&db=m Genetics of the epilepsies. causal interaction,ongoing research,unassigned 3,1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15115644&form=6&db=m Toward a molecular genetic classification of familial hemiplegic migraine. causal interaction,unassigned 3,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15133718&form=6&db=m A novel missense ATP1A2 mutation in a Finnish family with familial hemiplegic migraine type 2. causal interaction,unassigned 4,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15159495&form=6&db=m Variability of familial hemiplegic migraine with novel A1A2 Na+/K+-ATPase variants. causal interaction,unassigned 2,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15167062&form=6&db=m Recent findings in headache genetics. ongoing research,unassigned 2,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15210532&form=6&db=m No mutations in CACNA1A and ATP1A2 in probands with common types of migraine. causal interaction,diagnostic usage,unassigned 3,2,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15308625&form=6&db=m Kinetic alterations due to a missense mutation in the Na,K-ATPase alpha2 subunit cause familial hemiplegic migraine type 2. causal interaction,unassigned 4,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15346975&form=6&db=m [Genetics of migraines: from ionic channels to single nucleotide polymorphisms?] unassigned - 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15534763&form=6&db=m Alternating hemiplegia of childhood: no mutations in the second familial hemiplegic migraine gene ATP1A2. unassigned - 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15557518&form=6&db=m Single-fiber EMG in familial hemiplegic migraine. causal interaction,diagnostic usage,unassigned 2,1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15970628&form=6&db=m Functional effects of Na+,K+-ATPase gene mutations. causal interaction,unassigned 3,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15985592&form=6&db=m Opening of the blood-brain barrier preceding cortical edema in a severe attack of FHM type II. causal interaction,unassigned 4,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15987881&form=6&db=m Mutation in the glutamate transporter EAAT1 causes episodic ataxia, hemiplegia, and seizures. ongoing research,therapeutic application,unassigned 3,1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16054936&form=6&db=m Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine. ongoing research,unassigned 1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16080125&form=6&db=m Genomewide significant linkage to migrainous headache on chromosome 5q21. unassigned - 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16088919&form=6&db=m ATP1A2 mutations in 11 families with familial hemiplegic migraine. causal interaction,unassigned 4,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16110494&form=6&db=m Rare missense variants in ATP1A2 in families with clustering of common forms of migraine. causal interaction,unassigned 1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16116111&form=6&db=m Mutation in the glutamate transporter EAAT1 causes episodic ataxia, hemiplegia, and seizures. ongoing research,therapeutic application,unassigned 3,1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16157018&form=6&db=m Analysis of chromosome 1 microsatellite markers and the FHM2-ATP1A2 gene mutations in migraine pedigrees. diagnostic usage,unassigned 2,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16178956&form=6&db=m Familial hemiplegic migraine presenting as recurrent encephalopathy in a Native Indian family. causal interaction,unassigned 3,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16508934&form=6&db=m The CACNA1A and ATP1A2 genes are not involved in dominantly inherited migraine with aura. unassigned - 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16508935&form=6&db=m Haplotype-based systematic association studies of ATP1A2 in migraine with aura. causal interaction,unassigned 3,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16538223&form=6&db=m Two de novo mutations in the Na,K-ATPase gene ATP1A2 associated with pure familial hemiplegic migraine. unassigned - 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16567706&form=6&db=m Basilar-type migraine: clinical, epidemiologic, and genetic features. diagnostic usage,unassigned 3,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16597394&form=6&db=m [ATP1A2 : a key player in familial hemiplegic migraine.] causal interaction,unassigned 2,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16822249&form=6&db=m Linkage analysis and disease models in benign familial infantile seizures: a study of 16 families. causal interaction,ongoing research,unassigned 1,1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16866717&form=6&db=m Migrainous vertigo: mutation analysis of the candidate genes CACNA1A, ATP1A2, SCN1A, and CACNB4. causal interaction,therapeutic application,unassigned 2,1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16915377&form=6&db=m [Genetics of migraine] causal interaction,unassigned 2,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17395138&form=6&db=m Familial hemiplegic migraine. unassigned - 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17473835&form=6&db=m First case of compound heterozygosity in Na,K-ATPase gene ATP1A2 in familial hemiplegic migraine. causal interaction,unassigned 1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17877748&form=6&db=m Amino acid changes in the amino terminus of the Na,K-adenosine triphosphatase alpha-2 subunit associated to familial and sporadic hemiplegic migraine. causal interaction,unassigned 1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17952365&form=6&db=m Recurrent ATP1A2 mutations in Portuguese families with familial hemiplegic migraine. causal interaction,unassigned 3,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18028407&form=6&db=m Epilepsy as part of the phenotype associated with ATP1A2 mutations. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,3,1 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18028456&form=6&db=m Two novel functional mutations in the Na+,K+-ATPase alpha2-subunit ATP1A2 gene in patients with familial hemiplegic migraine and associated neurological phenotypes. causal interaction,therapeutic application,unassigned 3,1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18184292&form=6&db=m A novel ATP1A2 gene mutation in an Irish familial hemiplegic migraine kindred. causal interaction,unassigned 2,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18361423&form=6&db=m A genome-wide linkage scan provides evidence for both new and previously reported loci influencing common migraine. ongoing research,unassigned 1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18451712&form=6&db=m Genetics of migraine: an update with special attention to genetic comorbidity. causal interaction,unassigned 3,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18483709&form=6&db=m ATP1A2 gene mutations are not present in two sisters with basilar-type migraine associated with menses. causal interaction,therapeutic application,unassigned 3,1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18492448&form=6&db=m [The Na+,K+ pump continues to cause surprise] causal interaction,unassigned 3,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18498390&form=6&db=m Severe attacks of familial hemiplegic migraine, childhood epilepsy and ATP1A2 mutation. causal interaction,ongoing research,unassigned 3,3,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18513263&form=6&db=m Screen for CACNA1A and ATP1A2 mutations in sporadic hemiplegic migraine patients. causal interaction,ongoing research,unassigned 2,3,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18644608&form=6&db=m A novel de novo nonsense mutation in ATP1A2 associated with sporadic hemiplegic migraine and epileptic seizures. causal interaction,unassigned 2,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18728015&form=6&db=m Diverse functional consequences of mutations in the Na+/K+-ATPase alpha2-subunit causing familial hemiplegic migraine type 2. causal interaction,unassigned 3,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18957371&form=6&db=m The structure of the Na+,K+-ATPase and mapping of isoform differences and disease-related mutations. causal interaction,therapeutic application,unassigned 3,2,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19332696&form=6&db=m Elicited repetitive daily blindness: a new phenotype associated with hemiplegic migraine and SCN1A mutations. causal interaction,unassigned 3,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19372756&form=6&db=m Impaired plasma membrane targeting or protein stability by certain ATP1A2 mutations identified in sporadic or familial hemiplegic migraine. ongoing research,unassigned 1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19874388&form=6&db=m Familial hemiplegic migraine is associated with febrile seizures in an FHM2 family with a novel de novo ATP1A2 mutation. causal interaction,unassigned 4,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20236346&form=6&db=m Partially Reversible Cortical Metabolic Dysfunction in Familial Hemiplegic Migraine With Prolonged Aura. causal interaction,unassigned 3,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20495966&form=6&db=m Migraine and epilepsy: A focus on overlapping clinical, pathophysiological, molecular, and therapeutic aspects. causal interaction,unassigned 4,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20837964&form=6&db=m De novo mutations in ATP1A2 and CACNA1A are frequent in early-onset sporadic hemiplegic migraine. unassigned - 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21063360&form=6&db=m Coexistence of CACNA1A, ATP1A2, and KCNN3 gene mutation in migraine patients with human platelet polymorphism. ongoing research,unassigned 2,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21352219&form=6&db=m Prolonged sporadic hemiplegic migraine associated with a novel de novo missense ATP1A2 gene mutation. causal interaction,unassigned 4,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21855646&form=6&db=m Migraine: Role of the TRESK two-pore potassium channel. causal interaction,unassigned 3,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22013243&form=6&db=m Neurovascular changes in prolonged migraine aura in FHM with a novel ATP1A2 gene mutation. causal interaction,unassigned 2,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22117059&form=6&db=m Inhibition of phosphorylation of na+,k+-ATPase by mutations causing familial hemiplegic migraine. causal interaction,unassigned 3,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22483278&form=6&db=m The kinetics of non-synaptically triggered acute excitotoxic responses in the central nervous system observed using intrinsic optical signals. causal interaction,diagnostic usage,therapeutic application,unassigned 3,1,1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22759692&form=6&db=m A case of familial hemiplegic migraine associated with a novel ATP1A2 gene mutation. causal interaction,unassigned 4,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22883286&form=6&db=m Variable manifestations of familial hemiplegic migraine associated with reversible cerebral edema in children. causal interaction,unassigned 3,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23030542&form=6&db=m Identification of novel genes involved in migraine. causal interaction,unassigned 3,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23459313&form=6&db=m Polymorphisms in migraine-associated gene, atp1a2, and ischemic stroke risk in a biracial population: the genetics of early onset stroke study. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,2,2,1 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23561701&form=6&db=m Genetic effects of ATP1A2 in familial hemiplegic migraine type II and animal models. causal interaction,ongoing research,unassigned 4,4,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23761507&form=6&db=m Acute encephalopathy in familial hemiplegic migraine with ATP1A2 mutation. causal interaction,diagnostic usage,unassigned 4,1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23821026&form=6&db=m Hemiplegic migraine with reversible cerebral vasoconstriction caused by ATP1A2 mutations. causal interaction,unassigned 3,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23838748&form=6&db=m Functional characterization of a novel C-terminal ATP1A2 mutation causing hemiplegic migraine and epilepsy. causal interaction,ongoing research,unassigned 2,2,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23918834&form=6&db=m A novel ATP1A2 gene mutation in familial hemiplegic migraine and epilepsy. causal interaction,ongoing research,unassigned 4,2,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23954377&form=6&db=m Familial hemiplegic migraine mutations affect Na,K-ATPase domain interactions. unassigned - 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24096472&form=6&db=m Clinical spectrum in three families with familial hemiplegic migraine type 2 including a novel mutation in the ATP1A2 gene. causal interaction,ongoing research,therapeutic application,unassigned 4,2,1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24097848&form=6&db=m A Wide Clinical Phenotype Spectrum in Patients With ATP1A2 Mutations. causal interaction,ongoing research,unassigned 4,2,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24136331&form=6&db=m Pulmonary arterial hypertension in familial hemiplegic migraine with ATP1A2 channelopathy. unassigned - 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24396618&form=6&db=m Sporadic Hemiplegic Migraine with ATP1A2 and Prothrombin Gene Mutations. causal interaction,unassigned 4,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24498617&form=6&db=m Screening of CACNA1A and ATP1A2 genes in hemiplegic migraine: clinical, genetic, and functional studies. diagnostic usage,unassigned 2,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24921013&form=6&db=m Functional analysis of human Na(+)/K(+)-ATPase familial or sporadic hemiplegic migraine mutations expressed in Xenopus oocytes. causal interaction,unassigned 1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25138102&form=6&db=m A missense variant of the ATP1A2 gene is associated with a novel phenotype of progressive sensorineural hearing loss associated with migraine. causal interaction,ongoing research,therapeutic application,unassigned 4,2,1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25411546&form=6&db=m Biphasic neurovascular changes in prolonged migraine aura in familial hemiplegic migraine type 2. causal interaction,unassigned 2,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25476251&form=6&db=m Genome-wide screen for modifiers of Na + /K + ATPase alleles identifies critical genetic loci. causal interaction,therapeutic application,unassigned 3,1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26747084&form=6&db=m Genetic studies of Polish migraine patients: screening for causative mutations in four migraine-associated genes. causal interaction,unassigned 2,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27127758&form=6&db=m Migraine in the era of precision medicine. ongoing research,unassigned 2,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27199775&form=6&db=m Insights into the Pathology of the ?2-Na(+)/K(+)-ATPase in Neurological Disorders; Lessons from Animal Models. causal interaction,unassigned 1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27226003&form=6&db=m Recurrent coma and fever in familial hemiplegic migraine type 2. A prospective 15-year follow-up of a large family with a novel ATP1A2 mutation. ongoing research,unassigned 2,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27313535&form=6&db=m The Influence of Na(+), K(+)-ATPase on Glutamate Signaling in Neurodegenerative Diseases and Senescence. causal interaction,unassigned 1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27445835&form=6&db=m ATP1A2 Mutations in Migraine: Seeing through the Facets of an Ion Pump onto the Neurobiology of Disease. unassigned - 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27818813&form=6&db=m Familial Hemiplegic Migraine with Severe Attacks: A New Report with ATP1A2 Mutation. causal interaction,therapeutic application,unassigned 4,3,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28058944&form=6&db=m Epilepsy in hemiplegic migraine: Genetic mutations and clinical implications. causal interaction,diagnostic usage,ongoing research,unassigned 2,3,2,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28123025&form=6&db=m Sodium Pumps Mediate Activity-Dependent Changes in Mammalian Motor Networks. causal interaction,therapeutic application,unassigned 1,1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28185542&form=6&db=m Analysis of amplicon-based NGS data from neurological disease gene panels: a new method for allele drop-out management. diagnostic usage,ongoing research,therapeutic application,unassigned 1,1,1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28445178&form=6&db=m Familial Hemiplegic Migraine With Asymmetric Encephalopathy Secondary to ATP1A2 Mutation: A Case Series. unassigned - 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28479855&form=6&db=m The genetic relationship between epilepsy and hemiplegic migraine. unassigned - 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28527083&form=6&db=m Shared mechanisms of epilepsy, migraine and affective disorders. causal interaction,unassigned 4,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28593511&form=6&db=m De novo exonic duplication of ATP1A2 in Italian patient with hemiplegic migraine: a case report. ongoing research,therapeutic application,unassigned 2,2,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28637637&form=6&db=m Alternating hemiplegia of childhood and a pathogenic variant of ATP1A3: a case report and pathophysiological considerations. causal interaction,unassigned 3,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28702766&form=6&db=m Erratum to: De novo exonic duplication of ATP1A2 in Italian patient with hemiplegic migraine: a case report. unassigned - 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28811059&form=6&db=m An Infant With Epilepsy and Recurrent Hemiplegia due to Compound Heterozygous Variants in ATP1A2. causal interaction,unassigned 4,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29041816&form=6&db=m Enhanced susceptibility to cortical spreading depression in two types of Na causal interaction,ongoing research,unassigned 3,1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29486580&form=6&db=m The contribution of CACNA1A, ATP1A2 and SCN1A mutations in hemiplegic migraine: A clinical and genetic study in Finnish migraine families. causal interaction,ongoing research,unassigned 4,2,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29867740&form=6&db=m A Novel ATP1A2 Gene Variant Associated With Pure Sporadic Hemiplegic Migraine Improved After Patent Foramen Ovale Closure: A Case Report. causal interaction,unassigned 3,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30027842&form=6&db=m Migraine: Genetic Variants and Clinical Phenotypes. causal interaction,unassigned 3,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30167989&form=6&db=m New CACNA1A deletions are associated to migraine phenotypes. causal interaction,unassigned 3,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30446731&form=6&db=m Increased susceptibility to cortical spreading depression and epileptiform activity in a mouse model for FHM2. causal interaction,unassigned 1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30498473&form=6&db=m Familial Hemiplegic Migraine Type 3 (FHM3) With an SCN1A Mutation in a Chinese Family: A Case Report. causal interaction,unassigned 1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30690204&form=6&db=m Biallelic loss of function variants in ATP1A2 cause hydrops fetalis, microcephaly, arthrogryposis and extensive cortical malformations. causal interaction,unassigned 1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30819023&form=6&db=m Na+/K+-ATPase ? isoform deficiency results in distinct spreading depolarization phenotypes. ongoing research,unassigned 1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30922082&form=6&db=m Differential effect of FHM2 mutation on synaptic plasticity in distinct hippocampal regions. causal interaction,ongoing research,therapeutic application,unassigned 3,1,1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31053037&form=6&db=m A Chinese family with familial hemiplegic migraine type 2 due to a novel missense mutation in ATP1A2. causal interaction,unassigned 4,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31226929&form=6&db=m Advances in genetics of migraine. causal interaction,unassigned 1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31586957&form=6&db=m Novel missense mutation in the ATP1A2 gene associated with atypical sporapedic hemiplegic migraine. causal interaction,unassigned 4,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31608932&form=6&db=m A novel lethal recognizable polymicrogyric syndrome caused by ATP1A2 homozygous truncating variants. causal interaction,unassigned 3,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31766058&form=6&db=m Early Treatment in Acute Severe Encephalopathy Caused by ATP1A2 Mutation of Familial Hemiplegic Migraine Type 2: Case Report and Literature Review. causal interaction,therapeutic application,unassigned 4,4,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32233732&form=6&db=m Exploring Neuronal Vulnerability to Head Trauma Using a Whole Exome Approach. causal interaction,therapeutic application,unassigned 4,1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32237043&form=6&db=m Astrocytes in Atp1a2-deficient heterozygous mice exhibit hyperactivity after induction of cortical spreading depression. unassigned - 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32345385&form=6&db=m Prolonged Hyperperfusion in a Child With ATP1A2 Defect-Related Hemiplegic Migraine. therapeutic application,unassigned 1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32484063&form=6&db=m Characteristics of cortical spreading depression and c-Fos expression in transgenic mice having a mutation associated with familial hemiplegic migraine 2. causal interaction,unassigned 1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32549268&form=6&db=m Familial Hemiplegic Migraine with an ATP1A4 Mutation: Clinical Spectrum and Carbamazepine Efficacy. causal interaction,unassigned 3,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32920306&form=6&db=m Intravenous Nimodipine Treatment for Severe Episode of ATP1A2 Hemiplegic Migraine. therapeutic application,unassigned 4,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33493807&form=6&db=m Early onset severe ATP1A2 epileptic encephalopathy: Clinical characteristics and underlying mutations. causal interaction,therapeutic application,unassigned 4,2,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33578253&form=6&db=m A novel ATP1A2 variant associated with severe stepwise regression, hemiplegia, epilepsy and movement disorders in two unrelated patients. ongoing research,therapeutic application,unassigned 1,1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33711927&form=6&db=m Familial hemiplegic migraine type 2 due to a novel missense mutation in ATP1A2. causal interaction,unassigned 4,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33880529&form=6&db=m ATP1A2- and ATP1A3-associated early profound epileptic encephalopathy and polymicrogyria. causal interaction,therapeutic application,unassigned 4,1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33882852&form=6&db=m Serial magnetic resonance imaging findings during severe attacks of familial hemiplegic migraine type 2: a case report. causal interaction,unassigned 3,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33911866&form=6&db=m Exploring the Hereditary Nature of Migraine. causal interaction,unassigned 3,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34092402&form=6&db=m Hemiplegic migraine type 2 caused by a novel variant within the P-type ATPase motif in ATP1A2 concomitant with a CACNA1A variant. causal interaction,unassigned 3,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34135856&form=6&db=m CACNA1A-Linked Hemiplegic Migraine in GLUT 1 Deficiency Syndrome: A Case Report. causal interaction,unassigned 1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34320921&form=6&db=m CACNA1A-p.Thr501Met mutation associated with familial hemiplegic migraine: a family report. ongoing research,unassigned 1,0 7.2.2.3 Migraine Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34384358&form=6&db=m Functional correlation of ATP1A2 mutations with phenotypic spectrum: from pure hemiplegic migraine to its variant forms. causal interaction,unassigned 4,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12119109&form=6&db=m Physical mapping and characterization of the human Na,K-ATPase isoform, ATP1A4. ongoing research,unassigned 1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12539047&form=6&db=m Haploinsufficiency of ATP1A2 encoding the Na+/K+ pump alpha2 subunit associated with familial hemiplegic migraine type 2. causal interaction,therapeutic application,unassigned 1,1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12915447&form=6&db=m Significant linkage to migraine with aura on chromosome 11q24. causal interaction,unassigned 1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12953268&form=6&db=m Novel mutations in the Na+, K+-ATPase pump gene ATP1A2 associated with familial hemiplegic migraine and benign familial infantile convulsions. causal interaction,unassigned 3,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14624354&form=6&db=m Update on the genetics of migraine. causal interaction,therapeutic application,unassigned 3,1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14636773&form=6&db=m New discoveries about the second gene for familial hemiplegic migraine, ATP1A2. unassigned - 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15021241&form=6&db=m Genetics of the epilepsies. causal interaction,ongoing research,unassigned 3,1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15115644&form=6&db=m Toward a molecular genetic classification of familial hemiplegic migraine. causal interaction,unassigned 3,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15133718&form=6&db=m A novel missense ATP1A2 mutation in a Finnish family with familial hemiplegic migraine type 2. causal interaction,unassigned 4,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15159495&form=6&db=m Variability of familial hemiplegic migraine with novel A1A2 Na+/K+-ATPase variants. causal interaction,unassigned 2,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15167062&form=6&db=m Recent findings in headache genetics. ongoing research,unassigned 2,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15308625&form=6&db=m Kinetic alterations due to a missense mutation in the Na,K-ATPase alpha2 subunit cause familial hemiplegic migraine type 2. causal interaction,unassigned 4,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15346975&form=6&db=m [Genetics of migraines: from ionic channels to single nucleotide polymorphisms?] unassigned - 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15534763&form=6&db=m Alternating hemiplegia of childhood: no mutations in the second familial hemiplegic migraine gene ATP1A2. unassigned - 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15557518&form=6&db=m Single-fiber EMG in familial hemiplegic migraine. causal interaction,diagnostic usage,unassigned 2,1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15970628&form=6&db=m Functional effects of Na+,K+-ATPase gene mutations. causal interaction,unassigned 3,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16054936&form=6&db=m Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine. ongoing research,unassigned 1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16080125&form=6&db=m Genomewide significant linkage to migrainous headache on chromosome 5q21. unassigned - 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16088919&form=6&db=m ATP1A2 mutations in 11 families with familial hemiplegic migraine. causal interaction,unassigned 4,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16110494&form=6&db=m Rare missense variants in ATP1A2 in families with clustering of common forms of migraine. causal interaction,unassigned 1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16157018&form=6&db=m Analysis of chromosome 1 microsatellite markers and the FHM2-ATP1A2 gene mutations in migraine pedigrees. diagnostic usage,unassigned 2,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16178956&form=6&db=m Familial hemiplegic migraine presenting as recurrent encephalopathy in a Native Indian family. causal interaction,unassigned 3,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16344534&form=6&db=m Familial basilar migraine associated with a new mutation in the ATP1A2 gene. causal interaction,ongoing research,unassigned 4,1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16508934&form=6&db=m The CACNA1A and ATP1A2 genes are not involved in dominantly inherited migraine with aura. unassigned - 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16508935&form=6&db=m Haplotype-based systematic association studies of ATP1A2 in migraine with aura. causal interaction,unassigned 3,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16538223&form=6&db=m Two de novo mutations in the Na,K-ATPase gene ATP1A2 associated with pure familial hemiplegic migraine. unassigned - 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16567706&form=6&db=m Basilar-type migraine: clinical, epidemiologic, and genetic features. diagnostic usage,unassigned 3,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16597394&form=6&db=m [ATP1A2 : a key player in familial hemiplegic migraine.] causal interaction,unassigned 2,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16822249&form=6&db=m Linkage analysis and disease models in benign familial infantile seizures: a study of 16 families. causal interaction,ongoing research,unassigned 1,1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16866717&form=6&db=m Migrainous vertigo: mutation analysis of the candidate genes CACNA1A, ATP1A2, SCN1A, and CACNB4. causal interaction,therapeutic application,unassigned 2,1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16915377&form=6&db=m [Genetics of migraine] causal interaction,unassigned 2,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17473835&form=6&db=m First case of compound heterozygosity in Na,K-ATPase gene ATP1A2 in familial hemiplegic migraine. causal interaction,unassigned 1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17952365&form=6&db=m Recurrent ATP1A2 mutations in Portuguese families with familial hemiplegic migraine. causal interaction,unassigned 3,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18028407&form=6&db=m Epilepsy as part of the phenotype associated with ATP1A2 mutations. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,3,1 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18028456&form=6&db=m Two novel functional mutations in the Na+,K+-ATPase alpha2-subunit ATP1A2 gene in patients with familial hemiplegic migraine and associated neurological phenotypes. causal interaction,therapeutic application,unassigned 3,1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18184292&form=6&db=m A novel ATP1A2 gene mutation in an Irish familial hemiplegic migraine kindred. causal interaction,unassigned 2,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18361423&form=6&db=m A genome-wide linkage scan provides evidence for both new and previously reported loci influencing common migraine. ongoing research,unassigned 1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18451712&form=6&db=m Genetics of migraine: an update with special attention to genetic comorbidity. causal interaction,unassigned 3,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18483709&form=6&db=m ATP1A2 gene mutations are not present in two sisters with basilar-type migraine associated with menses. causal interaction,therapeutic application,unassigned 3,1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18492448&form=6&db=m [The Na+,K+ pump continues to cause surprise] causal interaction,unassigned 3,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18498390&form=6&db=m Severe attacks of familial hemiplegic migraine, childhood epilepsy and ATP1A2 mutation. causal interaction,ongoing research,unassigned 3,3,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18728015&form=6&db=m Diverse functional consequences of mutations in the Na+/K+-ATPase alpha2-subunit causing familial hemiplegic migraine type 2. causal interaction,unassigned 3,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18957371&form=6&db=m The structure of the Na+,K+-ATPase and mapping of isoform differences and disease-related mutations. causal interaction,therapeutic application,unassigned 3,2,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19332696&form=6&db=m Elicited repetitive daily blindness: a new phenotype associated with hemiplegic migraine and SCN1A mutations. causal interaction,unassigned 3,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19372756&form=6&db=m Impaired plasma membrane targeting or protein stability by certain ATP1A2 mutations identified in sporadic or familial hemiplegic migraine. ongoing research,unassigned 1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19874388&form=6&db=m Familial hemiplegic migraine is associated with febrile seizures in an FHM2 family with a novel de novo ATP1A2 mutation. causal interaction,unassigned 4,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20236346&form=6&db=m Partially Reversible Cortical Metabolic Dysfunction in Familial Hemiplegic Migraine With Prolonged Aura. causal interaction,unassigned 3,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21855646&form=6&db=m Migraine: Role of the TRESK two-pore potassium channel. causal interaction,unassigned 3,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22117059&form=6&db=m Inhibition of phosphorylation of na+,k+-ATPase by mutations causing familial hemiplegic migraine. causal interaction,unassigned 3,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22759692&form=6&db=m A case of familial hemiplegic migraine associated with a novel ATP1A2 gene mutation. causal interaction,unassigned 4,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22883286&form=6&db=m Variable manifestations of familial hemiplegic migraine associated with reversible cerebral edema in children. causal interaction,unassigned 3,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23030542&form=6&db=m Identification of novel genes involved in migraine. causal interaction,unassigned 3,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23459313&form=6&db=m Polymorphisms in migraine-associated gene, atp1a2, and ischemic stroke risk in a biracial population: the genetics of early onset stroke study. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,2,2,1 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23561701&form=6&db=m Genetic effects of ATP1A2 in familial hemiplegic migraine type II and animal models. causal interaction,ongoing research,unassigned 4,4,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23761507&form=6&db=m Acute encephalopathy in familial hemiplegic migraine with ATP1A2 mutation. causal interaction,diagnostic usage,unassigned 4,1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23838748&form=6&db=m Functional characterization of a novel C-terminal ATP1A2 mutation causing hemiplegic migraine and epilepsy. causal interaction,ongoing research,unassigned 2,2,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23918834&form=6&db=m A novel ATP1A2 gene mutation in familial hemiplegic migraine and epilepsy. causal interaction,ongoing research,unassigned 4,2,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24096472&form=6&db=m Clinical spectrum in three families with familial hemiplegic migraine type 2 including a novel mutation in the ATP1A2 gene. causal interaction,ongoing research,therapeutic application,unassigned 4,2,1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24097848&form=6&db=m A Wide Clinical Phenotype Spectrum in Patients With ATP1A2 Mutations. causal interaction,ongoing research,unassigned 4,2,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24136331&form=6&db=m Pulmonary arterial hypertension in familial hemiplegic migraine with ATP1A2 channelopathy. unassigned - 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25411546&form=6&db=m Biphasic neurovascular changes in prolonged migraine aura in familial hemiplegic migraine type 2. causal interaction,unassigned 2,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25476251&form=6&db=m Genome-wide screen for modifiers of Na + /K + ATPase alleles identifies critical genetic loci. causal interaction,therapeutic application,unassigned 3,1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26747084&form=6&db=m Genetic studies of Polish migraine patients: screening for causative mutations in four migraine-associated genes. causal interaction,unassigned 2,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27127758&form=6&db=m Migraine in the era of precision medicine. ongoing research,unassigned 2,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27199775&form=6&db=m Insights into the Pathology of the ?2-Na(+)/K(+)-ATPase in Neurological Disorders; Lessons from Animal Models. causal interaction,unassigned 1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27226003&form=6&db=m Recurrent coma and fever in familial hemiplegic migraine type 2. A prospective 15-year follow-up of a large family with a novel ATP1A2 mutation. ongoing research,unassigned 2,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27313535&form=6&db=m The Influence of Na(+), K(+)-ATPase on Glutamate Signaling in Neurodegenerative Diseases and Senescence. causal interaction,unassigned 1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27445835&form=6&db=m ATP1A2 Mutations in Migraine: Seeing through the Facets of an Ion Pump onto the Neurobiology of Disease. unassigned - 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27818813&form=6&db=m Familial Hemiplegic Migraine with Severe Attacks: A New Report with ATP1A2 Mutation. causal interaction,therapeutic application,unassigned 4,3,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28185542&form=6&db=m Analysis of amplicon-based NGS data from neurological disease gene panels: a new method for allele drop-out management. diagnostic usage,ongoing research,therapeutic application,unassigned 1,1,1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28445178&form=6&db=m Familial Hemiplegic Migraine With Asymmetric Encephalopathy Secondary to ATP1A2 Mutation: A Case Series. unassigned - 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28527083&form=6&db=m Shared mechanisms of epilepsy, migraine and affective disorders. causal interaction,unassigned 4,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28637637&form=6&db=m Alternating hemiplegia of childhood and a pathogenic variant of ATP1A3: a case report and pathophysiological considerations. causal interaction,unassigned 3,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28811059&form=6&db=m An Infant With Epilepsy and Recurrent Hemiplegia due to Compound Heterozygous Variants in ATP1A2. causal interaction,unassigned 4,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29041816&form=6&db=m Enhanced susceptibility to cortical spreading depression in two types of Na causal interaction,ongoing research,unassigned 3,1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29486580&form=6&db=m The contribution of CACNA1A, ATP1A2 and SCN1A mutations in hemiplegic migraine: A clinical and genetic study in Finnish migraine families. causal interaction,ongoing research,unassigned 4,2,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30167989&form=6&db=m New CACNA1A deletions are associated to migraine phenotypes. causal interaction,unassigned 3,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30446731&form=6&db=m Increased susceptibility to cortical spreading depression and epileptiform activity in a mouse model for FHM2. causal interaction,unassigned 1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30498473&form=6&db=m Familial Hemiplegic Migraine Type 3 (FHM3) With an SCN1A Mutation in a Chinese Family: A Case Report. causal interaction,unassigned 1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30690204&form=6&db=m Biallelic loss of function variants in ATP1A2 cause hydrops fetalis, microcephaly, arthrogryposis and extensive cortical malformations. causal interaction,unassigned 1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30819023&form=6&db=m Na+/K+-ATPase ? isoform deficiency results in distinct spreading depolarization phenotypes. ongoing research,unassigned 1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30922082&form=6&db=m Differential effect of FHM2 mutation on synaptic plasticity in distinct hippocampal regions. causal interaction,ongoing research,therapeutic application,unassigned 3,1,1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31053037&form=6&db=m A Chinese family with familial hemiplegic migraine type 2 due to a novel missense mutation in ATP1A2. causal interaction,unassigned 4,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31608932&form=6&db=m A novel lethal recognizable polymicrogyric syndrome caused by ATP1A2 homozygous truncating variants. causal interaction,unassigned 3,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31766058&form=6&db=m Early Treatment in Acute Severe Encephalopathy Caused by ATP1A2 Mutation of Familial Hemiplegic Migraine Type 2: Case Report and Literature Review. causal interaction,therapeutic application,unassigned 4,4,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32237043&form=6&db=m Astrocytes in Atp1a2-deficient heterozygous mice exhibit hyperactivity after induction of cortical spreading depression. unassigned - 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32484063&form=6&db=m Characteristics of cortical spreading depression and c-Fos expression in transgenic mice having a mutation associated with familial hemiplegic migraine 2. causal interaction,unassigned 1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32549268&form=6&db=m Familial Hemiplegic Migraine with an ATP1A4 Mutation: Clinical Spectrum and Carbamazepine Efficacy. causal interaction,unassigned 3,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33578253&form=6&db=m A novel ATP1A2 variant associated with severe stepwise regression, hemiplegia, epilepsy and movement disorders in two unrelated patients. ongoing research,therapeutic application,unassigned 1,1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33711927&form=6&db=m Familial hemiplegic migraine type 2 due to a novel missense mutation in ATP1A2. causal interaction,unassigned 4,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33880529&form=6&db=m ATP1A2- and ATP1A3-associated early profound epileptic encephalopathy and polymicrogyria. causal interaction,therapeutic application,unassigned 4,1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33911866&form=6&db=m Exploring the Hereditary Nature of Migraine. causal interaction,unassigned 3,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34320921&form=6&db=m CACNA1A-p.Thr501Met mutation associated with familial hemiplegic migraine: a family report. ongoing research,unassigned 1,0 7.2.2.3 Migraine with Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34384358&form=6&db=m Functional correlation of ATP1A2 mutations with phenotypic spectrum: from pure hemiplegic migraine to its variant forms. causal interaction,unassigned 4,0 7.2.2.3 Migraine without Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16157018&form=6&db=m Analysis of chromosome 1 microsatellite markers and the FHM2-ATP1A2 gene mutations in migraine pedigrees. diagnostic usage,unassigned 2,0 7.2.2.3 Migraine without Aura http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23954377&form=6&db=m Familial hemiplegic migraine mutations affect Na,K-ATPase domain interactions. unassigned - 7.2.2.3 Mitochondrial Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20207608&form=6&db=m A De Novo Mutation in the Adenosine Triphosphatase (ATPase) 8 Gene in a Patient With Mitochondrial Disorder. causal interaction,ongoing research,unassigned 1,2,0 7.2.2.3 Monoclonal Gammopathy of Undetermined Significance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=131873&form=6&db=m [The significance of the cytochemical adenosine triphosphatase reaction for the diagnosis of benign monoclonal gammopathy (author's transl)] causal interaction,diagnostic usage,unassigned 3,4,0 7.2.2.3 Mononeuropathies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6152683&form=6&db=m Endoneurial ATPase activity in Tangier disease and other peripheral neuropathies. causal interaction,diagnostic usage,ongoing research,unassigned 1,4,2,0 7.2.2.3 Mouth Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21327633&form=6&db=m Modulatory Action of ?-Tocopherol on Erythrocyte Membrane Adenosine Triphosphatase against Radiation Damage in Oral Cancer. ongoing research,therapeutic application,unassigned 2,2,0 7.2.2.3 Movement Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28472154&form=6&db=m Hypothermia-induced dystonia and abnormal cerebellar activity in a mouse model with a single disease-mutation in the sodium-potassium pump. causal interaction,unassigned 1,0 7.2.2.3 Movement Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32986028&form=6&db=m Implantation of Osmotic Pumps and Induction of Stress to Establish a Symptomatic, Pharmacological Mouse Model for DYT/PARK-ATP1A3 Dystonia. unassigned - 7.2.2.3 Movement Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33578253&form=6&db=m A novel ATP1A2 variant associated with severe stepwise regression, hemiplegia, epilepsy and movement disorders in two unrelated patients. ongoing research,therapeutic application,unassigned 1,1,0 7.2.2.3 Multiple Sclerosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6309073&form=6&db=m Na+- and K+-dependent adenosine triphosphatase changes in multiple sclerosis plaques. causal interaction,ongoing research,unassigned 4,3,0 7.2.2.3 Multiple Sclerosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6331279&form=6&db=m Na+- and K+-dependent adenosine triphosphatase and multiple sclerosis. unassigned - 7.2.2.3 Multiple Sclerosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21795050&form=6&db=m A novel mitochondrial DNA deletion producing progressive external ophthalmoplegia associated with multiple sclerosis. unassigned - 7.2.2.3 Muscle Hypotonia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32015920&form=6&db=m Ocular Hypotonia and Transient Decrease of Vision as a Consequence of Exposure to a Common Toad Poison. causal interaction,unassigned 4,0 7.2.2.3 Muscle Spasticity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3413042&form=6&db=m Diamphenethide--a reassessment of its pharmacological action. unassigned - 7.2.2.3 Muscle Spasticity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11579422&form=6&db=m Mitochondria and degenerative disorders. causal interaction,unassigned 3,0 7.2.2.3 Muscular Atrophy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16224848&form=6&db=m [Effects of Ligustrazine and Radix Astragali on activities of myosin adenosine triphosphatase of soleus muscle and muscle atrophy in tail-suspended rats] ongoing research,unassigned 2,0 7.2.2.3 Muscular Atrophy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21141606&form=6&db=m [The preventive effects of one herbal compound on activities of myosin adenosine triphosphatase of muscle fibers and muscle atrophy in tail-suspended rat]. ongoing research,therapeutic application,unassigned 2,1,0 7.2.2.3 Muscular Atrophy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25991827&form=6&db=m Aerobic Exercise Recovers Disuse-induced Atrophy Through the Stimulus of the LRP130/PGC-1? Complex in Aged Rats. causal interaction,diagnostic usage,unassigned 1,3,0 7.2.2.3 Muscular Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3811138&form=6&db=m Crooked calf disease: a histological and histochemical examination of eight affected calves. unassigned - 7.2.2.3 Muscular Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4236363&form=6&db=m Adenosine triphosphatase and myopathy. diagnostic usage,ongoing research,unassigned 3,3,0 7.2.2.3 Muscular Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11001821&form=6&db=m Gene-related protein surplus myopathies. causal interaction,unassigned 1,0 7.2.2.3 Muscular Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21795050&form=6&db=m A novel mitochondrial DNA deletion producing progressive external ophthalmoplegia associated with multiple sclerosis. unassigned - 7.2.2.3 Muscular Dystrophies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=131297&form=6&db=m [Sodium- and potassium-dependent adenosine triphosphatase of erythrocyte shadows in patients with Duchenne's myodystrophy] unassigned - 7.2.2.3 Muscular Dystrophies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4250479&form=6&db=m Ouabain and erythrocyte-ghost adenosine triphosphatase. Effects in human muscular dystrophies. ongoing research,unassigned 3,0 7.2.2.3 Muscular Dystrophies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6116221&form=6&db=m [Adenosine triphosphatase activities of the erythrocyte membrane in Duchenne's myodystrophy] unassigned - 7.2.2.3 Muscular Dystrophies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6276440&form=6&db=m Sodium channel and sodium pump in normal and pathological muscles from patients with myotonic muscular dystrophy and lower motor neuron impairment. causal interaction,diagnostic usage,ongoing research,unassigned 1,2,3,0 7.2.2.3 Muscular Dystrophy, Duchenne http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=75965&form=6&db=m The sodium pump of erythrocytes from patients with Duchenne muscular dystrophy: effect of ouabain on the active sodium flux and on (Na+, K+)ATPase. ongoing research,unassigned 3,0 7.2.2.3 Muscular Dystrophy, Duchenne http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=142127&form=6&db=m Erythrocyte cation-activated adenosine triphosphatases in Duchenne muscular dystrophy. diagnostic usage,ongoing research,unassigned 3,1,0 7.2.2.3 Muscular Dystrophy, Duchenne http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=145473&form=6&db=m Effect of ouabain upon erythrocyte membrane adenosine triphosphatase in Duchenne muscular dystrophy. diagnostic usage,unassigned 3,0 7.2.2.3 Muscular Dystrophy, Duchenne http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4255122&form=6&db=m Superprecipitation and adenosine triphosphatase activity of myosin B in Duchenne muscular dystrophy. unassigned - 7.2.2.3 Muscular Dystrophy, Duchenne http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6111509&form=6&db=m Erythrocyte membrane (Ca/+ + Mg/+)-activated adenosine triphosphatase in Duchenne muscular dystrophy. unassigned - 7.2.2.3 Muscular Dystrophy, Duchenne http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6124239&form=6&db=m Erythrocyte-ghost Ca2+-stimulated Mg2+-dependent adenosine triphosphatase in Duchenne muscular dystrophy. diagnostic usage,ongoing research,unassigned 1,3,0 7.2.2.3 Muscular Dystrophy, Duchenne http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6251175&form=6&db=m Specificity of biophysical and biochemical alterations in erythrocyte membranes in neurological disorders--Huntington's disease, Friedreich's ataxia, Alzheimer's disease, amyotrophic lateral sclerosis, and myotonic and duchenne muscular dystrophy. diagnostic usage,therapeutic application,unassigned 3,1,0 7.2.2.3 Muscular Dystrophy, Duchenne http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6450703&form=6&db=m The effect of ouabain on erythrocyte adenosine triphosphatase activity in relation to cell age in vivo and Duchenne muscular dystrophy. diagnostic usage,ongoing research,unassigned 3,4,0 7.2.2.3 Myalgia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31198938&form=6&db=m Investigation of the relationships between different enzymes and postmortem duck muscle tenderization. ongoing research,unassigned 2,0 7.2.2.3 Myocardial Infarction http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6142703&form=6&db=m Immunofluorescent microscopy for the identification of human necrotic myocardium. therapeutic application,unassigned 2,0 7.2.2.3 Myocardial Infarction http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9576120&form=6&db=m Characterization of a urinary bufodienolide Na+,K+-ATPase inhibitor in patients after acute myocardial infarction. diagnostic usage,ongoing research,therapeutic application,unassigned 3,2,4,0 7.2.2.3 Myocardial Infarction http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11746581&form=6&db=m Noninvasive quantification of total sodium concentrations in acute reperfused myocardial infarction using 23Na MRI. causal interaction,therapeutic application,unassigned 3,1,0 7.2.2.3 Myocardial Infarction http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17289242&form=6&db=m Preventive effect of naringin on isoproterenol-induced cardiotoxicity in Wistar rats: an in vivo and in vitro study. diagnostic usage,ongoing research,unassigned 3,2,0 7.2.2.3 Myocardial Infarction http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19067678&form=6&db=m Preventive effect of S-allylcysteine on membrane-bound enzymes and glycoproteins in normal and isoproterenol-induced cardiac toxicity in male Wistar rats. ongoing research,unassigned 1,0 7.2.2.3 Myocardial Infarction http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21698512&form=6&db=m Pretreatment with morin, a flavonoid, ameliorates adenosine triphosphatases and glycoproteins in isoproterenol-induced myocardial infarction in rats. therapeutic application,unassigned 1,0 7.2.2.3 Myocardial Infarction http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21834631&form=6&db=m Protective effect of Lagenaria siceraria (Mol) against membrane-bound enzyme alterations in isoproterenol-induced cardiac damage in rats. unassigned - 7.2.2.3 Myocardial Infarction http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23459313&form=6&db=m Polymorphisms in migraine-associated gene, atp1a2, and ischemic stroke risk in a biracial population: the genetics of early onset stroke study. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,2,2,1 7.2.2.3 Myocardial Infarction http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34448639&form=6&db=m The ?2-isoform of the Na+/K+-ATPase protects against pathological remodeling and ?-adrenergic desensitization after myocardial infarction. causal interaction,therapeutic application,unassigned 4,2,0 7.2.2.3 Myocardial Ischemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1455831&form=6&db=m [The effect of laser irradiation of the blood on the adenosine triphosphatase activity of the erythrocyte membranes and on the cardiac activity indices in patients with ischemic heart disease] ongoing research,therapeutic application,unassigned 3,1,0 7.2.2.3 Myocardial Ischemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1838226&form=6&db=m [Study of the calmodulin-dependent regulation of calcium adenosine triphosphatase of erythrocyte membranes in patients with ischemic heart disease] causal interaction,diagnostic usage,ongoing research,unassigned 1,1,2,0 7.2.2.3 Myocardial Ischemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15013017&form=6&db=m Benzodiazepine-based selective inhibitors of mitochondrial F1F0 ATP hydrolase. causal interaction,therapeutic application,unassigned 3,4,0 7.2.2.3 Myocardial Ischemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16100049&form=6&db=m Calpain-mediated impairment of Na+/K+-ATPase activity during early reperfusion contributes to cell death after myocardial ischemia. causal interaction,ongoing research,therapeutic application,unassigned 2,2,1,0 7.2.2.3 Myocardial Ischemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19035880&form=6&db=m Pharmacological profile of the selective mitochondrial F1F0 ATP hydrolase inhibitor BMS-199264 in myocardial ischemia. therapeutic application,unassigned 4,0 7.2.2.3 Myocardial Ischemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33781843&form=6&db=m Alleviation of isoprenaline hydrochloride induced myocardial ischemia injury by brucine through the inhibition of Na+/K+-ATPase. causal interaction,unassigned 2,0 7.2.2.3 Myocardial Reperfusion Injury http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20130737&form=6&db=m Antidigoxin antiserum prevents endogenous digitalis-like compound-mediated reperfusion injury via modulating sodium pump isoform gene expression. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,4,3 7.2.2.3 Myocardial Stunning http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18373391&form=6&db=m Lack of the effect of superoxide dismutase and catalase on Na+,K+-ATPase activity in stunned rabbit hearts. unassigned - 7.2.2.3 Myocarditis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4247015&form=6&db=m [The catecholamine concentration and adenosine triphosphatase activity of the myocardium in experimental myocarditis] ongoing research,unassigned 1,0 7.2.2.3 Myopia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32418893&form=6&db=m Disrupted potassium ion homeostasis in ciliary muscle in negative lens-induced myopia in Guinea pigs. unassigned - 7.2.2.3 Myotonia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4265797&form=6&db=m Diazacholesterol myotonia: accumulation of desmosterol and increased adenosine triphosphatase activity of sarcolemma. unassigned - 7.2.2.3 Myotonia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6288437&form=6&db=m Membrane desmosterol and the kinetics of the sarcolemmal Na+,K+-ATPase in myotonia induced by 20,25-diazacholesterol. unassigned - 7.2.2.3 Myotonic Dystrophy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2907504&form=6&db=m Localization of a human Na+,K+-ATPase alpha subunit gene to chromosome 19q12----q13.2 and linkage to the myotonic dystrophy locus. ongoing research,unassigned 3,0 7.2.2.3 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15563845&form=6&db=m Identification and cloning of genes displaying elevated expression as a consequence of metastatic progression in human melanoma cells by rapid subtraction hybridization. unassigned - 7.2.2.3 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25647733&form=6&db=m Side population cells and drug resistance in breast cancer. causal interaction,unassigned 4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22952&form=6&db=m [HCO3-stimulated adenosine triphosphatase in rat ovarian tumor cells] causal interaction,diagnostic usage,ongoing research,unassigned 2,1,4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=124205&form=6&db=m A Mg2+- and Ca2+-stimulated adenosine triphosphatase at the outer surface of Ehrlich ascites tumor cells. diagnostic usage,unassigned 3,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=132271&form=6&db=m Ultrastructural and cytochemical studies on hyperbasophilic foci with special reference to the demonstration of cell surface alterations in hepatocarcinogenesis. unassigned - 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=167945&form=6&db=m A comparative study of inner membrane enzymes and transport systems in mitochondria from R3230AC mammary tumor and normal rat mammary gland. unassigned - 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=192083&form=6&db=m Ultrastructural localization of membrane phosphatases in teratocarcinoma and early embryos. causal interaction,diagnostic usage,ongoing research,unassigned 1,1,4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=818869&form=6&db=m [Histochemical and ultrastructural investigations on organ culture of malignant tumors (author's transl)] ongoing research,unassigned 3,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1012292&form=6&db=m [Cytomorphological and enzyme histological studies of bilaterally inoculated Dibromdulcit-sensitive and-resistent Yoshida tumors] unassigned - 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1728855&form=6&db=m Lymph node interdigitating cell sarcoma. A case report. diagnostic usage,unassigned 3,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1830824&form=6&db=m Differential sensitivity of human gastric cancer ATPase and normal gastric mucosa ATPase to the synthetic mammalian lignan analogue 2,3-dibenzylbutane-1,4-diol (hattalin). diagnostic usage,ongoing research,unassigned 1,4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2422723&form=6&db=m Morphologic and cytochemical properties of mouse liver neoplasms induced by diethylnitrosamine and promoted by 4,4'-dichlorodiphenyltrichloroethane, chlordane, or heptachlor. diagnostic usage,unassigned 1,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2447103&form=6&db=m Activation and proliferation signals in murine macrophages: stimulation of Na+,K+-ATPase activity by hemopoietic growth factors and other agents. unassigned - 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2454758&form=6&db=m [Photodynamic effect of a hematoporphyrin derivative on the sodium pump activity and aerobic glycolysis in tumor cells] ongoing research,unassigned 3,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2666517&form=6&db=m Histogenesis of Kaposi's sarcoma and angiosarcoma of the face and the scalp. causal interaction,ongoing research,unassigned 2,2,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2834164&form=6&db=m [Differential expression of 2 genes of the Na+,K+-AtPase subunit in normal and tumor tissues in humans] ongoing research,unassigned 3,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2887455&form=6&db=m Family of Na+,K+-ATPase genes. Intra-individual tissue-specific restriction fragment length polymorphism. causal interaction,diagnostic usage,ongoing research,unassigned 4,1,4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2947801&form=6&db=m Quantification of ATP-producing and consuming processes of Ehrlich ascites tumour cells. unassigned - 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2964490&form=6&db=m Suppressor cell activation and enhanced skin allograft survival after tumor promotor but not initiator induced depletion of cutaneous Langerhans cells. causal interaction,therapeutic application,unassigned 3,1,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2984662&form=6&db=m Correlation of ouabain-sensitive ion movements with cell-cycle activation. causal interaction,unassigned 3,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3010699&form=6&db=m Enzyme histochemistry and thyroid neoplasia. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,2,1 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3010748&form=6&db=m Malignant fibrous histiocytoma tumor cells resemble fibroblasts. ongoing research,unassigned 2,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3034663&form=6&db=m (3H)ouabain binding to leukaemic cells and intralymphocytic sodium content in chronic lymphocytic leukaemia; no evidence for alterations of the Na+/K+-pump. causal interaction,therapeutic application,unassigned 2,2,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3159641&form=6&db=m An evaluation of enzyme histochemistry in the diagnosis of childhood rhabdomyosarcoma. diagnostic usage,therapeutic application,unassigned 4,1,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3886125&form=6&db=m A distinctive cutaneous malignant neoplasm expressing the Langerhans cell phenotype. Synchronous occurrence with B-chronic lymphocytic leukemia. causal interaction,diagnostic usage,unassigned 2,3,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4235483&form=6&db=m [Significance of the inhibition of adenosine triphosphatase of the red splenic pulp during the development of tumor transplants in rats] causal interaction,ongoing research,unassigned 3,2,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4254752&form=6&db=m [Action of thymic lipid extract B on adenosine triphosphatase and succinate dehydrogenase of the liver of rats with Guerin tumors] ongoing research,unassigned 3,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4305234&form=6&db=m An electron cytochemical demonstration and biochemical analysis of adenosine triphosphatase activity in cancer cell plasma membrane. diagnostic usage,ongoing research,unassigned 4,4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4337092&form=6&db=m [Adenosine triphosphatase activity in the plasmatic membranes of cancer cells] ongoing research,unassigned 3,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4364650&form=6&db=m Uncoupler-stimulated adenosine triphosphatase activity. Deficiency in intact mitochondria from Morris hepatomas and ascites tumor cells. unassigned - 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4374859&form=6&db=m The fine structural localisation of thiamine pyrophosphatase and adenosine triphosphatase in neural tumours induced by N-ethyl-N-nitrosourea in rats. unassigned - 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4404199&form=6&db=m Increase in adenosine triphosphatase activity of Ehrlich ascites tumor cells following serial cultivation in media with increased (hypertonic) NaCl content. unassigned - 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6100219&form=6&db=m Serum and hepatic enzyme activity in rats treated with diethylnitrosamine. causal interaction,diagnostic usage,therapeutic application,unassigned 4,4,4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6100583&form=6&db=m Inhibition of tumor growth by an alkylation of the plasma membrane. unassigned - 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6105895&form=6&db=m [Ultracytochemical study of the nucleoside phosphatase activity of nuclei of epithelial cells of the gastric mucosa and of stomach cancer cells in humans] causal interaction,diagnostic usage,ongoing research,unassigned 1,3,4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6148924&form=6&db=m A cytochemical study on the salivary gland pleomorphic adenoma (mixed tumor) and the fetal and adult salivary gland. ongoing research,unassigned 4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6161957&form=6&db=m Immune and enzyme histochemical studies of a human hepatocellular carcinoma cell line producing hepatitis B surface antigen. unassigned - 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6211417&form=6&db=m Quercetin inhibition of the induction and function of cytotoxic T lymphocytes. ongoing research,unassigned 2,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6223476&form=6&db=m Sarcoma arising from interdigitating cells. Cytology and cytochemistry. diagnostic usage,ongoing research,unassigned 3,3,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6258585&form=6&db=m Ecto-enzymes of mammary gland and its tumours. Ca2+- or Mg2+-stimulated adenosine triphosphatase and its perturbation by concanavalin A. unassigned - 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6293160&form=6&db=m Epithelioid sarcoma. Enzyme histochemical and ultrastructural study. ongoing research,unassigned 3,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6297258&form=6&db=m Enzyme histochemical study on bone tumors. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,1,2 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6461125&form=6&db=m Vascular tumors of the mammary gland. A histochemical and ultrastructural study. ongoing research,unassigned 2,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6737010&form=6&db=m Primary rhabdomyosarcoma of the cerebellum--a light, electron microscopic, and immunohistochemical study. ongoing research,unassigned 1,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8162598&form=6&db=m One-megabase yeast artificial chromosome and 400-kilobase cosmid-phage contigs containing the von Hippel-Lindau tumor suppressor and Ca(2+)-transporting adenosine triphosphatase isoform 2 genes. ongoing research,unassigned 2,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8190400&form=6&db=m Experimental evaluation of the usefulness of 201Tl-chloride scintigraphy for monitoring radiotherapeutic effects. unassigned - 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8564963&form=6&db=m Impairment of sodium pump and Na+/H+ antiport in erythrocytes isolated from cancer patients. diagnostic usage,ongoing research,therapeutic application,unassigned 2,3,1,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9731897&form=6&db=m Intracellular accumulation of thallium as a marker of cisplatin cytotoxicity in nonsmall cell lung carcinoma: an application of inductively coupled plasma mass spectrometry. unassigned - 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9848104&form=6&db=m Sodium pump and Na+/H+ antiport restoration in erythrocytes from cancer patients in remission. causal interaction,ongoing research,unassigned 1,3,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10882332&form=6&db=m Treatment of ras-induced cancers by the F-actin-bundling drug MKT-077. causal interaction,unassigned 4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11219852&form=6&db=m Alteration by phenobarbital of membrane-associated enzymes including gamma glutamyl transpeptidase in mouse liver neoplasms. ongoing research,unassigned 3,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11355005&form=6&db=m Polyamines secreted by cancer cells possibly account for the impairment of the human erythrocyte sodium pump activity. diagnostic usage,ongoing research,unassigned 3,4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12786941&form=6&db=m Different roles of proteolipids and 70-kDa subunits of V-ATPase in growth and death of cultured human cells. unassigned - 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14115448&form=6&db=m [HISTOCHEMICAL DEMONSTRATION OF ADENOSINE TRIPHOSPHATASE ACTIVITY IN TRANSPLANTABLE TUMORS AND CORRESPONDING NORMAL TISSUES.] ongoing research,unassigned 4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15961594&form=6&db=m Thallium-201 chloride (Tl-201) accumulation and Na+/K+-ATPase expression in tumours of the head and neck. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,4,3,1 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16105948&form=6&db=m Enhancing the anticancer properties of cardiac glycosides by neoglycorandomization. causal interaction,unassigned 1,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16790089&form=6&db=m Cardenolide-induced lysosomal membrane permeabilization demonstrates therapeutic benefits in experimental human non-small cell lung cancers. causal interaction,unassigned 4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17147266&form=6&db=m [Na+,K+-ATPase and Ca2+-ATPase isozymes in malignant neoplasms] diagnostic usage,unassigned 1,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17706876&form=6&db=m Cardiotonic steroids on the road to anti-cancer therapy. causal interaction,therapeutic application,unassigned 4,4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17976639&form=6&db=m Transgenic overexpression of translationally controlled tumor protein induces systemic hypertension via repression of Na+,K+-ATPase. causal interaction,therapeutic application,unassigned 4,4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18219996&form=6&db=m [Na+,K+ -ATPase activity characteristics in human colon adenocarcinoma] causal interaction,diagnostic usage,ongoing research,unassigned 4,3,3,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18390407&form=6&db=m [The sodium pump could constitute a new target to combat glioblastomas] causal interaction,ongoing research,therapeutic application,unassigned 3,4,3,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18851696&form=6&db=m Na+/K+-ATPase alpha subunits as new targets in anticancer therapy. causal interaction,unassigned 4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19194651&form=6&db=m Editorial: on the road to multi-modal and pluri-disciplinary treatment of glioblastomas. causal interaction,diagnostic usage,therapeutic application,unassigned 4,3,4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19243476&form=6&db=m The Sodium Pump alpha1 Subunit: a Disease Progression-Related Target for Metastatic Melanoma Treatment. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,4,4 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19293189&form=6&db=m Inhibition of the sodium potassium adenosine triphosphatase pump sensitizes cancer cells to anoikis and prevents distant tumor formation. causal interaction,ongoing research,therapeutic application,unassigned 1,4,2,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19440057&form=6&db=m Digitalis, a targeted therapy for cancer? causal interaction,therapeutic application,unassigned 3,3,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19447218&form=6&db=m UNBS1450 from Calotropis procera as a regulator of signaling pathways involved in proliferation and cell death. unassigned - 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20509963&form=6&db=m Early uptake and continuous accumulation of thallium-201 chloride in a benign mixed tumor of soft tissue: Case Report. causal interaction,ongoing research,unassigned 3,4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21178005&form=6&db=m Tumor-associated a2 vacuolar ATPase acts as a key mediator of cancer-related inflammation by inducing pro-tumorigenic properties in monocytes. unassigned - 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22048701&form=6&db=m Effect of Ginkgo biloba extract 50 on immunity and antioxidant enzyme activities in ischemia reperfusion rats. diagnostic usage,therapeutic application,unassigned 1,1,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22127853&form=6&db=m Bilirubin attenuates bufadienolide-induced ventricular arrhythmias and cardiac dysfunction in Guinea-pigs by reducing elevated intracellular na(+) levels. causal interaction,unassigned 3,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22204337&form=6&db=m Cardiotonic Steroids-Mediated Targeting of the Na(+)/K(+)-ATPase to Combat Chemoresistant Cancers. causal interaction,unassigned 2,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22253825&form=6&db=m Bone marrow-infiltrating human neuroblastoma cells express high levels of calprotectin and HLA-G proteins. causal interaction,ongoing research,unassigned 1,2,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22745436&form=6&db=m Engineering a prostate-specific membrane antigen-activated tumor endothelial cell prodrug for cancer therapy. causal interaction,ongoing research,unassigned 4,3,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22966294&form=6&db=m ATP7B expression is associated with in vitro sensitivity to cisplatin in non-small cell lung cancer. causal interaction,diagnostic usage,therapeutic application,unassigned 3,3,2,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22966390&form=6&db=m Association of ATP7A expression and in vitro sensitivity to cisplatin in non-small cell lung cancer. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,4,1 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23412992&form=6&db=m Cardiotonic Steroids-Mediated Na+/K+-ATPase Targeting Could Circumvent Various Chemoresistance Pathways. causal interaction,diagnostic usage,therapeutic application,unassigned 4,3,1,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23537048&form=6&db=m From Na+/K+-ATpase and Cardiac Glycosides to Cytotoxicity and Cancer Treatment. diagnostic usage,therapeutic application,unassigned 1,4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23615397&form=6&db=m Cardiac glycosides block cancer growth through HIF-1?- and NF-?B-mediated Plk1. causal interaction,therapeutic application,unassigned 1,4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23621895&form=6&db=m Hellebrin and its aglycone form hellebrigenin display similar in vitro growth inhibitory effects in cancer cells and binding profiles to the alpha subunits of the Na+/K+-ATPase. causal interaction,ongoing research,therapeutic application,unassigned 1,3,1,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24236716&form=6&db=m Na+/K+-ATPase and cancer. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,3 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24414985&form=6&db=m Hepatoprotective effect of Caesalpinia gilliesii and Cajanus cajan proteins against acetoaminophen overdose-induced hepatic damage. diagnostic usage,ongoing research,unassigned 1,1,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24920093&form=6&db=m Anticancer ruthenium(III) complex KP1019 interferes with ATP-dependent Ca2+ translocation by sarco-endoplasmic reticulum Ca2+-ATPase (SERCA). causal interaction,therapeutic application,unassigned 2,4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25175170&form=6&db=m ARID1A immunohistochemistry improves outcome prediction in invasive urothelial carcinoma of urinary bladder. therapeutic application,unassigned 1,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25202402&form=6&db=m Rabeprazole exhibits antiproliferative effects on human gastric cancer cell lines. diagnostic usage,therapeutic application,unassigned 1,1,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25452433&form=6&db=m Histopathological and Immunohistochemical Characterization of Methyl Eugenol-induced Nonneoplastic and Neoplastic Neuroendocrine Cell Lesions in Glandular Stomach of Rats. diagnostic usage,ongoing research,unassigned 1,1,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25647733&form=6&db=m Side population cells and drug resistance in breast cancer. causal interaction,unassigned 4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25936661&form=6&db=m Activation of novel estrogen receptor GPER results in inhibition of cardiocyte apoptosis and cardioprotection. diagnostic usage,ongoing research,unassigned 4,2,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26170660&form=6&db=m Nonspecifically enhanced therapeutic effects of vincristine on multidrug-resistant cancers when coencapsulated with quinine in liposomes. ongoing research,unassigned 2,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26622799&form=6&db=m ATPase inhibitory factor 1 is a potential prognostic marker for the migration and invasion of glioma. causal interaction,diagnostic usage,therapeutic application,unassigned 4,4,1,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26622894&form=6&db=m Expression of the copper transporters hCtr1, ATP7A and ATP7B is associated with the response to chemotherapy and survival time in patients with resected non-small cell lung cancer. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,3,1 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26822609&form=6&db=m 2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition. therapeutic application,unassigned 2,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26870246&form=6&db=m BRIP1 inhibits the tumorigenic properties of cervical cancer by regulating RhoA GTPase activity. causal interaction,therapeutic application,unassigned 3,1,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26910837&form=6&db=m Targeting FXYD2 by cardiac glycosides potently blocks tumor growth in ovarian clear cell carcinoma. ongoing research,unassigned 4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27722820&form=6&db=m Downregulation of RUVBL1 inhibits proliferation of lung adenocarcinoma cells by G1/S phase cell cycle arrest via multiple mechanisms. therapeutic application,unassigned 1,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27894666&form=6&db=m Ouabain induces apoptosis and autophagy in Burkitt's lymphoma Raji cells. therapeutic application,unassigned 2,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29501170&form=6&db=m A new water-soluble polythiophene derivative as a probe for real-time monitoring adenosine 5'-triphosphatase activity in lysosome of living cells. diagnostic usage,therapeutic application,unassigned 4,1,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29568394&form=6&db=m Cardiac glycoside bufalin blocks cancer cell growth by inhibition of Aurora A and Aurora B activation via PI3K-Akt pathway. causal interaction,therapeutic application,unassigned 4,4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29777796&form=6&db=m Identification of a sodium pump Na+/K+ ATPase ?1-targeted peptide for PET imaging of breast cancer. causal interaction,therapeutic application,unassigned 3,2,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29970705&form=6&db=m Evaluation of the relationship of erythrocyte membrane Na+/K+-ATPase enzyme activity and tumor response to chemoradiotherapy in patients diagnosed with locally advanced nonsmall cell lung cancer and glioblastoma multiforme. diagnostic usage,ongoing research,therapeutic application,unassigned 4,1,1,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29985440&form=6&db=m Cancer mortality does not differ by antiarrhythmic drug use: A population-based cohort of Finnish men. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,4,3,1 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30107342&form=6&db=m Cytotoxicity of AMANTADIG - a semisynthetic digitoxigenin derivative - alone and in combination with docetaxel in human hormone-refractory prostate cancer cells and its effect on Na+/K+-ATPase inhibition. causal interaction,ongoing research,therapeutic application,unassigned 4,1,4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30130132&form=6&db=m Update on the effects of the sodium pump ?1 subunit on human glioblastoma: from the laboratory to the clinic. causal interaction,ongoing research,therapeutic application,unassigned 3,4,4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30204757&form=6&db=m The vacuolar-type ATPase inhibitor archazolid increases tumor cell adhesion to endothelial cells by accumulating extracellular collagen. causal interaction,ongoing research,therapeutic application,unassigned 4,3,4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30251696&form=6&db=m Crosstalk between Na+,K+-ATPase and a volume-regulated anion channel in membrane microdomains of human cancer cells. ongoing research,unassigned 4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30447700&form=6&db=m Anti-inflammatory effects induced by pharmaceutical substances on inflammatory active brain astrocytes-promising treatment of neuroinflammation. diagnostic usage,unassigned 1,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30458280&form=6&db=m Hepatoprotective potential of standardized Ficus species in intrahepatic cholestasis rat model: Involvement of nuclear factor-?B, and Farnesoid X receptor signaling pathways. causal interaction,ongoing research,unassigned 1,1,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30712966&form=6&db=m Investigation of dose-dependent effects of berberine against renal ischemia/reperfusion injury in experimental diabetic rats. diagnostic usage,ongoing research,unassigned 4,1,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31060669&form=6&db=m [A Simple Medical Research Microdevice for Analyzing Three-dimensional Migration of Tumor Cells in Vitro]. ongoing research,unassigned 3,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31391478&form=6&db=m Plumbagin-induced oxidative stress leads to inhibition of Na+/K+-ATPase (NKA) in canine cancer cells. causal interaction,ongoing research,therapeutic application,unassigned 1,2,1,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31527358&form=6&db=m [Cancer cell-specific functional relation between Na+,K+-ATPase and volume-regulated anion channel]. causal interaction,therapeutic application,unassigned 3,4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31891085&form=6&db=m New 99mTc-Labeled Digitoxigenin Derivative for Cancer Cell Identification. ongoing research,unassigned 4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31934199&form=6&db=m Expression of ATP7A in esophageal squamous cell carcinoma (ESCC) and its clinical significance. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32096998&form=6&db=m Na+/K+-ATPase-Targeted Cytotoxicity of (+)-Digoxin and Several Semisynthetic Derivatives. therapeutic application,unassigned 1,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32349518&form=6&db=m Cinobufagin Triggers Defects in Spindle Formation and Cap-Dependent Translation in Liver Cancer Cells by Inhibiting the AURKA-mTOR-eIF4E Axis. causal interaction,diagnostic usage,unassigned 3,1,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32440992&form=6&db=m Mitophagy Induced by Mitochondrial Function Damage in Chicken Kidney Exposed to Cr(VI). unassigned - 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32588858&form=6&db=m A near-infrared light-controlled, ultrasensitive one-step photoelectrochemical detection of dual cell apoptosis indicators in living cancer cells. ongoing research,unassigned 3,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32731591&form=6&db=m Oxidative Stress and Apoptotic Responses Elicited by Nostoc-Synthesized Silver Nanoparticles against Different Cancer Cell Lines. ongoing research,therapeutic application,unassigned 4,1,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32808078&form=6&db=m Tumour blood flow for prediction of human prostate cancer aggressiveness: a study with Rubidium-82 PET, MRI and Na+/K+-ATPase-density. diagnostic usage,ongoing research,unassigned 1,1,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33122944&form=6&db=m ATP6AP2 is Overexpressed in Breast Cancer and Promotes Breast Cancer Progression. causal interaction,unassigned 3,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33254543&form=6&db=m Hypotheses about sub-optimal hydration in the weeks before coronavirus disease (COVID-19) as a risk factor for dying from COVID-19. causal interaction,unassigned 3,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33440629&form=6&db=m Steroid Glycosides Hyrcanoside and Deglucohyrcanoside: On Isolation, Structural Identification, and Anticancer Activity. causal interaction,therapeutic application,unassigned 2,4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33548025&form=6&db=m The Effect of Curcumin Nanoparticles on Cisplatin-Induced Cardiotoxicity in Male Wistar Albino Rats. ongoing research,therapeutic application,unassigned 4,2,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33800655&form=6&db=m Na+/K+-ATPase Revisited: On Its Mechanism of Action, Role in Cancer, and Activity Modulation. causal interaction,ongoing research,therapeutic application,unassigned 3,1,4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33997694&form=6&db=m Survival of detached cancer cells is regulated by movement of intracellular Na+,K+-ATPase. diagnostic usage,ongoing research,unassigned 3,4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34208576&form=6&db=m Structural Insights into the Interactions of Digoxin and Na+/K+-ATPase and Other Targets for the Inhibition of Cancer Cell Proliferation. causal interaction,therapeutic application,unassigned 2,2,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34251542&form=6&db=m The expression of the alpha1 subunit of Na+/K+-ATPase is related to tumor development and clinical outcomes in gastric cancer. causal interaction,diagnostic usage,ongoing research,unassigned 4,2,4,0 7.2.2.3 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34277430&form=6&db=m Cardiac Glycoside Ouabain Exerts Anticancer Activity via Downregulation of STAT3. causal interaction,therapeutic application,unassigned 3,4,0 7.2.2.3 Nephritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10489230&form=6&db=m Glomerulonephritis and sodium retention: enhancement of Na+/K+-ATPase activity in the collecting duct is shared by rats with puromycin induced nephrotic syndrome and mice with spontaneous lupus-like glomerulonephritis. ongoing research,unassigned 3,0 7.2.2.3 Nephrosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14320956&form=6&db=m OBSERVATIONS OF RAT KIDNEY MITOCHONDRIAL ADENOSINE TRIPHOSPHATASE ACTIVITY DURING INDUCTION OF AMINONUCLEOSIDE NEPHROSIS. causal interaction,ongoing research,unassigned 1,2,0 7.2.2.3 Nephrosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16267158&form=6&db=m Hyperaldosteronemia and activation of the epithelial sodium channel are not required for sodium retention in puromycin-induced nephrosis. causal interaction,unassigned 3,0 7.2.2.3 Nephrotic Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10489230&form=6&db=m Glomerulonephritis and sodium retention: enhancement of Na+/K+-ATPase activity in the collecting duct is shared by rats with puromycin induced nephrotic syndrome and mice with spontaneous lupus-like glomerulonephritis. ongoing research,unassigned 3,0 7.2.2.3 Nephrotic Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12814058&form=6&db=m [Cellular and molecular mechanisms of sodium pump activation in experimental models of nephrotic syndrome] ongoing research,therapeutic application,unassigned 2,3,0 7.2.2.3 Nephrotic Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16267158&form=6&db=m Hyperaldosteronemia and activation of the epithelial sodium channel are not required for sodium retention in puromycin-induced nephrosis. causal interaction,unassigned 3,0 7.2.2.3 Nephrotic Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19034867&form=6&db=m Nephrotic syndrome: new concepts in the pathophysiology of sodium retention. therapeutic application,unassigned 1,0 7.2.2.3 Nervous System Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6251175&form=6&db=m Specificity of biophysical and biochemical alterations in erythrocyte membranes in neurological disorders--Huntington's disease, Friedreich's ataxia, Alzheimer's disease, amyotrophic lateral sclerosis, and myotonic and duchenne muscular dystrophy. diagnostic usage,therapeutic application,unassigned 3,1,0 7.2.2.3 Nervous System Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7668837&form=6&db=m A novel mitochondrial ATPase 6 point mutation in familial bilateral striatal necrosis. unassigned - 7.2.2.3 Nervous System Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10452526&form=6&db=m Short-term block of Na+/K+-ATPase in neuro-glial cell cultures of cerebellum induces glutamate dependent damage of granule cells. unassigned - 7.2.2.3 Nervous System Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18492448&form=6&db=m [The Na+,K+ pump continues to cause surprise] causal interaction,unassigned 3,0 7.2.2.3 Nervous System Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27199775&form=6&db=m Insights into the Pathology of the ?2-Na(+)/K(+)-ATPase in Neurological Disorders; Lessons from Animal Models. causal interaction,unassigned 1,0 7.2.2.3 Nervous System Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27313535&form=6&db=m The Influence of Na(+), K(+)-ATPase on Glutamate Signaling in Neurodegenerative Diseases and Senescence. causal interaction,unassigned 1,0 7.2.2.3 Nervous System Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30760526&form=6&db=m Asparagine-905 of the mammalian phospholipid flippase ATP8A2 is essential for lipid substrate-induced activation of ATP8A2 dephosphorylation. causal interaction,therapeutic application,unassigned 1,1,0 7.2.2.3 Nervous System Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33544780&form=6&db=m Decreased content of ascorbic acid (vitamin C) in the brain of knockout mouse models of Na+,K+-ATPase-related neurologic disorders. unassigned - 7.2.2.3 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=133250&form=6&db=m The chronic and acute effects of ethanol on adenosine triphosphatase activity in cultured astroblast and neuroblastoma cells. ongoing research,unassigned 4,0 7.2.2.3 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=147979&form=6&db=m Stimulation of the membrane-bound, magnesium-dependent adenosine triphosphatase of mouse neuroblastoma by concanavalin A and wheat germ agglutinin. diagnostic usage,unassigned 3,0 7.2.2.3 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2588350&form=6&db=m [Rapid simultaneous isolation of microsomes and plasma membranes from neuroblastoma C 1300 N 18 cells] diagnostic usage,ongoing research,unassigned 3,2,0 7.2.2.3 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3301413&form=6&db=m Acute changes in myo-inositol uptake and 22Na+ flux in murine neuroblastoma cells (N1E-115) following insulin. ongoing research,unassigned 4,0 7.2.2.3 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6289988&form=6&db=m Alterations of membrane integrity and cellular constituents by arachidonic acid in neuroblastoma and glioma cells. ongoing research,therapeutic application,unassigned 3,1,0 7.2.2.3 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6308015&form=6&db=m Membrane regulation of the Na+,K+-ATPase during the neuroblastoma cell cycle: correlation with protein lateral mobility. ongoing research,unassigned 3,0 7.2.2.3 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8412773&form=6&db=m Reversal of hyperglycemic-induced defects in myo-inositol metabolism and Na+/K+ pump activity in cultured neuroblastoma cells by normalizing glucose levels. ongoing research,unassigned 3,0 7.2.2.3 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10503960&form=6&db=m Cilostazol, a cyclic AMP phosphodiesterase inhibitor, stimulates nitric oxide production and sodium potassium adenosine triphosphatase activity in SH-SY5Y human neuroblastoma cells. ongoing research,unassigned 4,0 7.2.2.3 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19154108&form=6&db=m Ostreocin-D impact on globular actin of intact cells. unassigned - 7.2.2.3 Neuroblastoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20218987&form=6&db=m Sodium pump alpha1 and alpha3 subunit isoforms mediate distinct responses to ouabain and are both essential for survival of human neuroblastoma. ongoing research,unassigned 4,0 7.2.2.3 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9452509&form=6&db=m Functional expression of the menkes disease protein reveals common biochemical mechanisms among the copper-transporting P-type ATPases. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,1,3,1 7.2.2.3 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16603790&form=6&db=m Copper homeostasis in the CNS: a novel link between the NMDA receptor and copper homeostasis in the hippocampus. causal interaction,unassigned 3,0 7.2.2.3 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17151944&form=6&db=m Kynurenines impair energy metabolism in rat cerebral cortex. causal interaction,ongoing research,unassigned 4,3,0 7.2.2.3 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17215139&form=6&db=m ATP7A (Menkes protein) functions in axonal targeting and synaptogenesis. causal interaction,unassigned 4,0 7.2.2.3 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17336116&form=6&db=m Safety of intracerebroventricular copper histidine in adult rats. unassigned - 7.2.2.3 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21878905&form=6&db=m ATP7A gene addition to the choroid plexus results in long-term rescue of the lethal copper transport defect in a Menkes disease mouse model. causal interaction,unassigned 4,0 7.2.2.3 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22574873&form=6&db=m In vitro studies of the influence of glutamatergic agonists on the Na+,K+-ATPase and K+-p-nitrophenylphosphatase activities in the hippocampus and frontal cortex of rats. causal interaction,unassigned 3,0 7.2.2.3 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23224983&form=6&db=m L-Threo-Dihydroxyphenylserine corrects neurochemical abnormalities in a menkes disease mouse model. causal interaction,unassigned 4,0 7.2.2.3 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25618580&form=6&db=m Possible involvement of membrane lipids peroxidation and oxidation of catalytically essential thiols of the cerebral transmembrane sodium pump as component mechanisms of iron-mediated oxidative stress-linked dysfunction of the pump's activity. unassigned - 7.2.2.3 Neurodegenerative Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32592177&form=6&db=m Multi-angle development of therapeutic methods for Alzheimer's disease. causal interaction,unassigned 3,0 7.2.2.3 Neuroinflammatory Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32843655&form=6&db=m The ?2 Na+/K+-ATPase isoform mediates LPS-induced neuroinflammation. therapeutic application,unassigned 1,0 7.2.2.3 Neuronal Ceroid-Lipofuscinoses http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23393156&form=6&db=m Atp13a2-deficient mice exhibit neuronal ceroid lipofuscinosis, limited ?-synuclein accumulation and age-dependent sensorimotor deficits. causal interaction,unassigned 2,0 7.2.2.3 Newcastle Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4380355&form=6&db=m Adenosine triphosphatase associated with Newcastle disease virus. Conditions for its optimum activity. diagnostic usage,therapeutic application,unassigned 1,1,0 7.2.2.3 Non-alcoholic Fatty Liver Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30588181&form=6&db=m Phenotypic Alteration of Hepatocytes in Non-Alcoholic Fatty Liver Disease. causal interaction,unassigned 2,0 7.2.2.3 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=224709&form=6&db=m Na+,K+-ATPase enzyme units in lean and obese (ob/ob) thyroxine-injected mice. ongoing research,unassigned 2,0 7.2.2.3 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2448070&form=6&db=m The effect of oral glucose on the leucocyte sodium pump in normal and obese subjects. causal interaction,unassigned 2,0 7.2.2.3 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3415795&form=6&db=m Endogenous digitalislike substance in an adult population in Japan. causal interaction,unassigned 4,0 7.2.2.3 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4075528&form=6&db=m A reproducible procedure for measuring sodium transport in cultured human fibroblasts from normal and obese donors. causal interaction,therapeutic application,unassigned 4,1,0 7.2.2.3 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6091947&form=6&db=m Erythrocyte sodium pump activity in human obesity. ongoing research,unassigned 4,0 7.2.2.3 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6252462&form=6&db=m Reduced activity of the red-cell sodium-potassium pump in human obesity. causal interaction,ongoing research,unassigned 4,2,0 7.2.2.3 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6277981&form=6&db=m Reduced Na+, K+ -ATPase activity in intact red cells and isolated membranes from obese man. causal interaction,therapeutic application,unassigned 1,1,0 7.2.2.3 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6300177&form=6&db=m Is the erythrocyte sodium pump altered in human obesity? causal interaction,therapeutic application,unassigned 3,1,0 7.2.2.3 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6302395&form=6&db=m Erythrocyte sodium-potassium-stimulated adenosine triphosphatase activity is not related to obesity. unassigned - 7.2.2.3 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6444702&form=6&db=m Obesity, thermogenesis and the sodium pump. unassigned - 7.2.2.3 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7219902&form=6&db=m Obesity, thermogenesis and the sodium pump. unassigned - 7.2.2.3 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16286513&form=6&db=m Hyperphagia and obesity in Na,K-ATPase alpha2 subunit-defective mice. causal interaction,ongoing research,therapeutic application,unassigned 2,2,3,0 7.2.2.3 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18282556&form=6&db=m Transactivation of epidermal growth factor receptor in vascular and renal systems in rats with experimental hyperleptinemia: role in leptin-induced hypertension. causal interaction,ongoing research,therapeutic application,unassigned 3,2,4,0 7.2.2.3 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20009768&form=6&db=m Two-dimensional, sex-specific autosomal linkage scan of the number of sodium pump sites. therapeutic application,unassigned 1,0 7.2.2.3 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23785175&form=6&db=m Effects of obesity and estradiol on Na+/K+-ATPase and their relevance to cardiovascular diseases. ongoing research,therapeutic application,unassigned 4,1,0 7.2.2.3 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28164755&form=6&db=m Regulation of Na+/K+-ATPase by Estradiol and IGF-1 in Cardio-Metabolic Diseases. causal interaction,diagnostic usage,therapeutic application,unassigned 3,3,4,0 7.2.2.3 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33081045&form=6&db=m The Cardiotonic Steroid Marinobufagenin Is a Predictor of Increased Left Ventricular Mass in Obesity: The African-PREDICT Study. causal interaction,therapeutic application,unassigned 1,1,0 7.2.2.3 Obstetric Labor, Premature http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16875653&form=6&db=m Alterations in uterine sodium pump abundance may contribute to the onset and progression of term and preterm labor in mice. causal interaction,diagnostic usage,ongoing research,unassigned 2,3,1,0 7.2.2.3 Oligospermia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6451923&form=6&db=m Reduced activity of Mg2+- and Ca2+-dependent adenosine triphosphatase in seminal fluid of patients with oligozoospermia. causal interaction,diagnostic usage,unassigned 4,2,0 7.2.2.3 Ophthalmoplegia, Chronic Progressive External http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21795050&form=6&db=m A novel mitochondrial DNA deletion producing progressive external ophthalmoplegia associated with multiple sclerosis. unassigned - 7.2.2.3 Optic Atrophy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27313535&form=6&db=m The Influence of Na(+), K(+)-ATPase on Glutamate Signaling in Neurodegenerative Diseases and Senescence. causal interaction,unassigned 1,0 7.2.2.3 Optic Atrophy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29305691&form=6&db=m The CAPOS mutation in ATP1A3 alters Na/K-ATPase function and results in auditory neuropathy which has implications for management. causal interaction,unassigned 2,0 7.2.2.3 Optic Atrophy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30409907&form=6&db=m Functional consequences of the CAPOS mutation E818K of Na+,K+-ATPase. unassigned - 7.2.2.3 Optic Atrophy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33880529&form=6&db=m ATP1A2- and ATP1A3-associated early profound epileptic encephalopathy and polymicrogyria. causal interaction,therapeutic application,unassigned 4,1,0 7.2.2.3 Osteoarthritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2820052&form=6&db=m Decreased NA+, K+-ATPase activity in erythrocyte membrane from rheumatoid arthritis patients. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,2,0 7.2.2.3 Osteoarthritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24009010&form=6&db=m The effects of osteoarthritis and age on skeletal muscle strength, Na+,K+-ATPase content, gene and isoform expression. ongoing research,unassigned 4,0 7.2.2.3 Osteosarcoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3008394&form=6&db=m Human osteogenic sarcoma: fine structural localization of adenosine triphosphatase. ongoing research,unassigned 4,0 7.2.2.3 Overweight http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2582182&form=6&db=m The sodium pump and energy regulation: some new aspects for essential hypertension, diabetes II and severe overweight. causal interaction,therapeutic application,unassigned 3,2,0 7.2.2.3 Overweight http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2612017&form=6&db=m Leucocyte sodium content and sodium pump activity in overweight and lean hypertensives. causal interaction,diagnostic usage,ongoing research,unassigned 4,1,3,0 7.2.2.3 Overweight http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32285837&form=6&db=m Peculiarities of the effects of bile acids on atpase activity of the colon mucosa in patients with overweight and irritable bowel syndrome. diagnostic usage,ongoing research,unassigned 2,4,0 7.2.2.3 p-type na+ transporter deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=127784&form=6&db=m Physiological suppression of a transport defect in Escherichia coli mutants deficient in Ca2+, Mg2+-stimulated adenosine triphosphatase. unassigned - 7.2.2.3 p-type na+ transporter deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2966306&form=6&db=m Sarcoplasmic reticulum adenosine triphosphatase deficiency with probable autosomal dominant inheritance. causal interaction,unassigned 2,0 7.2.2.3 p-type na+ transporter deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4274944&form=6&db=m Renal sodium- and potassium-activated adenosine triphosphatase deficiency during post-obstructive diuresis in the rat. causal interaction,ongoing research,unassigned 2,2,0 7.2.2.3 p-type na+ transporter deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8331362&form=6&db=m Exertional rhabdomyolysis in a patient with calcium adenosine triphosphatase deficiency. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,1,0 7.2.2.3 p-type phospholipid transporter deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19918981&form=6&db=m Folding defects in P-type ATP 8B1 associated with hereditary cholestasis are ameliorated by 4-phenylbutyrate. causal interaction,unassigned 4,0 7.2.2.3 p-type phospholipid transporter deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30881940&form=6&db=m In-silico Evaluation of Rare Codons and their Positions in the Structure of ATP8b1 Gene. causal interaction,unassigned 3,0 7.2.2.3 p-type phospholipid transporter deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33437900&form=6&db=m Assessment of Adenosine Triphosphatase Phospholipid Transporting 8B1 (ATP8B1) Function in Patients With Cholestasis With ATP8B1 Deficiency by Using Peripheral Blood Monocyte-Derived Macrophages. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,2,2,1 7.2.2.3 Pancreatitis, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2558124&form=6&db=m Immunohistochemical localization of Na+, K+-ATPase in human normal and malignant pancreatic tissues. causal interaction,ongoing research,unassigned 2,4,0 7.2.2.3 Paralysis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1660744&form=6&db=m In vivo and in vitro sodium pump activity in subjects with thyrotoxic periodic paralysis. diagnostic usage,ongoing research,unassigned 2,2,0 7.2.2.3 Paralysis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3413042&form=6&db=m Diamphenethide--a reassessment of its pharmacological action. unassigned - 7.2.2.3 Paralysis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8110464&form=6&db=m A mutation of the Drosophila sodium pump alpha subunit gene results in bang-sensitive paralysis. causal interaction,therapeutic application,unassigned 2,1,0 7.2.2.3 Paralysis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15853829&form=6&db=m Arg16Gly polymorphism in beta2-adrenergic receptor gene is not associated with thyrotoxic periodic paralysis in Korean male patients with Graves' disease. unassigned - 7.2.2.3 Paralysis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25783847&form=6&db=m Intratympanic steroid injection as a first-line therapy in uremia patients with sudden sensorineural hearing loss. causal interaction,unassigned 3,0 7.2.2.3 Paralysis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29844617&form=6&db=m Genistein: is the multifarious botanical a natural anthelmintic too? unassigned - 7.2.2.3 Paralysis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30423015&form=6&db=m A novel ATP1A2 mutation in a patient with hypokalaemic periodic paralysis and CNS symptoms. causal interaction,therapeutic application,unassigned 4,3,0 7.2.2.3 Paramyxoviridae Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33935717&form=6&db=m Na+/K+-ATPase as a Target of Cardiac Glycosides for the Treatment of SARS-CoV-2 Infection. causal interaction,therapeutic application,unassigned 3,4,0 7.2.2.3 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18569015&form=6&db=m Quinone and oxyradical scavenging properties of N-acetylcysteine prevent dopamine mediated inhibition of Na+, K+-ATPase and mitochondrial electron transport chain activity in rat brain: implications in the neuroprotective therapy of Parkinson's disease. causal interaction,unassigned 4,0 7.2.2.3 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19097176&form=6&db=m Genetic association study of the P-type ATPase ATP13A2 in late-onset Parkinson's disease. causal interaction,unassigned 3,0 7.2.2.3 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22647602&form=6&db=m Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration. causal interaction,unassigned 4,0 7.2.2.3 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23929762&form=6&db=m The human tongue slows down to speak: muscle fibers of the human tongue. diagnostic usage,ongoing research,unassigned 3,4,0 7.2.2.3 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24399444&form=6&db=m Parkinson's disease-associated human ATP13A2 (PARK9) deficiency causes zinc dyshomeostasis and mitochondrial dysfunction. causal interaction,unassigned 3,0 7.2.2.3 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27073711&form=6&db=m Protection against Mitochondrial and Metal Toxicity Depends on Functional Lipid Binding Sites in ATP13A2. causal interaction,unassigned 4,0 7.2.2.3 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28185542&form=6&db=m Analysis of amplicon-based NGS data from neurological disease gene panels: a new method for allele drop-out management. diagnostic usage,ongoing research,therapeutic application,unassigned 1,1,1,0 7.2.2.3 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29169913&form=6&db=m The strategic function of the P5-ATPase ATP13A2 in toxic waste disposal. causal interaction,unassigned 2,0 7.2.2.3 Parkinson Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32592177&form=6&db=m Multi-angle development of therapeutic methods for Alzheimer's disease. causal interaction,unassigned 3,0 7.2.2.3 Parkinsonian Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16632466&form=6&db=m Mutations Phe785Leu and Thr618Met in Na+,K+-ATPase, associated with familial rapid-onset dystonia parkinsonism, interfere with Na+ interaction by distinct mechanisms. therapeutic application,unassigned 1,0 7.2.2.3 Parkinsonian Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16964263&form=6&db=m Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase. causal interaction,unassigned 3,0 7.2.2.3 Parkinsonian Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18957371&form=6&db=m The structure of the Na+,K+-ATPase and mapping of isoform differences and disease-related mutations. causal interaction,therapeutic application,unassigned 3,2,0 7.2.2.3 Parkinsonian Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21542062&form=6&db=m Pathogenic effects of novel mutations in the P-type ATPase ATP13A2 (PARK9) causing Kufor-Rakeb syndrome, a form of early-onset parkinsonism. causal interaction,unassigned 3,0 7.2.2.3 Parkinsonian Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22198378&form=6&db=m ATP13A2 regulates mitochondrial bioenergetics through macroautophagy. causal interaction,unassigned 4,0 7.2.2.3 Parkinsonian Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22647602&form=6&db=m Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration. causal interaction,unassigned 4,0 7.2.2.3 Parkinsonian Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22768177&form=6&db=m Common pathogenic effects of missense mutations in the P-type ATPase ATP13A2 (PARK9) associated with early-onset parkinsonism. causal interaction,unassigned 3,0 7.2.2.3 Parkinsonian Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22847264&form=6&db=m Characterization of cellular protective effects of ATP13A2/PARK9 expression and alterations resulting from pathogenic mutants. causal interaction,unassigned 4,0 7.2.2.3 Parkinsonian Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23499937&form=6&db=m ATP13A2 deficiency induces a decrease in cathepsin D activity, fingerprint-like inclusion body formation, and selective degeneration of dopaminergic neurons. causal interaction,unassigned 3,0 7.2.2.3 Parkinsonian Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25476251&form=6&db=m Genome-wide screen for modifiers of Na + /K + ATPase alleles identifies critical genetic loci. causal interaction,therapeutic application,unassigned 3,1,0 7.2.2.3 Parkinsonian Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25713066&form=6&db=m Rescue of Na+ Affinity in Aspartate-928 Mutants of Na+,K+-ATPase by Secondary Mutation of Glutamate-314. unassigned - 7.2.2.3 Parkinsonian Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27073711&form=6&db=m Protection against Mitochondrial and Metal Toxicity Depends on Functional Lipid Binding Sites in ATP13A2. causal interaction,unassigned 4,0 7.2.2.3 Parkinsonian Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28123025&form=6&db=m Sodium Pumps Mediate Activity-Dependent Changes in Mammalian Motor Networks. causal interaction,therapeutic application,unassigned 1,1,0 7.2.2.3 Parkinsonian Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28472154&form=6&db=m Hypothermia-induced dystonia and abnormal cerebellar activity in a mouse model with a single disease-mutation in the sodium-potassium pump. causal interaction,unassigned 1,0 7.2.2.3 Pemphigus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4256409&form=6&db=m [Adenosine triphosphatase activity in human skin under normal conditions and in chronic pemphigus] diagnostic usage,ongoing research,unassigned 1,4,0 7.2.2.3 Peptic Ulcer http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1673953&form=6&db=m Treatment of refractory peptic ulcer with omeprazole or continued H2 receptor antagonists: a controlled clinical trial. therapeutic application,unassigned 4,0 7.2.2.3 Periapical Periodontitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32847752&form=6&db=m Apical periodontitis induces changes on oxidative stress parameters and increases Na+/K+-ATPase activity in adult rats. causal interaction,ongoing research,therapeutic application,unassigned 1,4,1,0 7.2.2.3 Periodontitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16805684&form=6&db=m Comparative analysis of the effects of a novel vacuolar adenosine 5'-triphosphatase inhibitor, FR202126, and doxycycline on bone loss caused by experimental periodontitis in rats. causal interaction,ongoing research,therapeutic application,unassigned 4,2,4,0 7.2.2.3 Peripheral Nervous System Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6152683&form=6&db=m Endoneurial ATPase activity in Tangier disease and other peripheral neuropathies. causal interaction,diagnostic usage,ongoing research,unassigned 1,4,2,0 7.2.2.3 Phenylketonurias http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6289150&form=6&db=m Effects of phenylalanine and its deaminated metabolites on Na+,K+-ATPase activity in synaptosomes from rat brain. unassigned - 7.2.2.3 Phenylketonurias http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10488911&form=6&db=m Alanine prevents the decrease of Na+,K+-ATPase activity in experimental phenylketonuria. diagnostic usage,ongoing research,therapeutic application,unassigned 1,3,3,0 7.2.2.3 Phenylketonurias http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11926533&form=6&db=m Effects of L-phenylalanine on acetylcholinesterase and Na+,K+-ATPase activities in suckling rat frontal cortex, hippocampus and hypothalamus. causal interaction,unassigned 3,0 7.2.2.3 Phenylketonurias http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12135689&form=6&db=m In vivo effects of high phenylalanine blood levels on Na+,K+-ATPase, Mg2+-ATPase activities and biogenic amine concentrations in phenylketonuria. ongoing research,unassigned 3,0 7.2.2.3 Pheochromocytoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2447235&form=6&db=m Nerve growth factor induces Na+,K+-ATPase in a nerve cell line. ongoing research,unassigned 4,0 7.2.2.3 Photosensitivity Disorders http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10209209&form=6&db=m The effect of hypericin and hypocrellin-A on lipid membranes and membrane potential of 3T3 fibroblasts. unassigned - 7.2.2.3 Placental Insufficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30684642&form=6&db=m Complex, coordinated and highly regulated changes in placental signaling and nutrient transport capacity in IUGR. causal interaction,unassigned 2,0 7.2.2.3 Plasmacytoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2983988&form=6&db=m Specific involvement of calmodulin and non-specific effect of tropomyosin in the sensitivity to ouabain of Na+,K+-ATPase in murine plasmocytoma cells. ongoing research,therapeutic application,unassigned 4,1,0 7.2.2.3 Plasmacytoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4181912&form=6&db=m [The cutologic diagnosis of a plasmacytoma of a bone marrow smear by means of the adenosine triphosphatase reaction] unassigned - 7.2.2.3 Plasmacytoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4237548&form=6&db=m [Diagnosis of plasmocytoma using the adenosine triphosphatase reaction on bone marrow smears] diagnostic usage,therapeutic application,unassigned 4,1,0 7.2.2.3 Pneumonia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12746451&form=6&db=m Pulmonary inflammation and edema induced by phospholipase A2: global gene analysis and effects on aquaporins and Na+/K+-ATPase. ongoing research,therapeutic application,unassigned 3,3,0 7.2.2.3 Pneumonia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20852622&form=6&db=m Dynamic regulation of cardiolipin by the lipid pump Atp8b1 determines the severity of lung injury in experimental pneumonia. causal interaction,ongoing research,therapeutic application,unassigned 3,2,1,0 7.2.2.3 Pneumoperitoneum http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22426903&form=6&db=m The effects of sevoflurane and propofol anesthesia on renal sodium-potassium adenosine triphosphatase activity during pneumoperitoneum in rats. diagnostic usage,ongoing research,therapeutic application,unassigned 3,4,1,0 7.2.2.3 Polycystic Kidney Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=141575&form=6&db=m [Progressive reduction of alkaline phosphatase and of Mg-dependent adenosine triphosphatase (Mg-ATPase) in congenital polycystic kidney in PM/Se mice] ongoing research,unassigned 1,0 7.2.2.3 Polycystic Kidney Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1323837&form=6&db=m Abnormal sodium pump distribution during renal tubulogenesis in congenital murine polycystic kidney disease. ongoing research,unassigned 3,0 7.2.2.3 Polycystic Kidney Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7919157&form=6&db=m Sodium pump distribution is not reversed in the DBA/2FG-pcy, polycystic kidney disease model mouse. ongoing research,therapeutic application,unassigned 4,2,0 7.2.2.3 Polycystic Kidney Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9142048&form=6&db=m A role for Na/K adenosine triphosphatase in the pathogenesis of cyst formation in experimental polycystic kidney disease. causal interaction,unassigned 4,0 7.2.2.3 Polymicrogyria http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33880529&form=6&db=m ATP1A2- and ATP1A3-associated early profound epileptic encephalopathy and polymicrogyria. causal interaction,therapeutic application,unassigned 4,1,0 7.2.2.3 Polyuria http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6291345&form=6&db=m The pathophysiology of septic shock: acute renal failure in rats following live E coli injection. A histochemical study of the proximal tubules. causal interaction,unassigned 1,0 7.2.2.3 Porcine Reproductive and Respiratory Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27065122&form=6&db=m The effect of porcine reproductive and respiratory syndrome virus and porcine epidemic diarrhea virus challenge on growing pigs II: Intestinal integrity and function. unassigned - 7.2.2.3 Potassium Deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6329516&form=6&db=m Adaptation of the cardiac muscle sodium pump to chronic potassium deficiency. causal interaction,therapeutic application,unassigned 4,1,0 7.2.2.3 Pre-Eclampsia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7449259&form=6&db=m Leucocyte electrolytes and sodium efflux rate constants in the hypertension of pre-eclampsia. causal interaction,unassigned 4,0 7.2.2.3 Pre-Eclampsia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7977547&form=6&db=m Preeclampsia and calcium adenosine triphosphatase activity of red blood cell ghosts. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,3,4,1 7.2.2.3 Pre-Eclampsia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9500507&form=6&db=m Preeclampsia, lipid peroxidation, and calcium adenosine triphosphatase activity of red blood cell ghosts. diagnostic usage,ongoing research,unassigned 1,4,0 7.2.2.3 Pre-Eclampsia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9704761&form=6&db=m Regulation of the sodium pump in pregnancy-related tissues in preeclampsia. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,4,1 7.2.2.3 Pre-Eclampsia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10466474&form=6&db=m Circulating bufodienolide and cardenolide sodium pump inhibitors in preeclampsia. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,3,2,3 7.2.2.3 Pre-Eclampsia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15702788&form=6&db=m [Activities of respiratory chain enzymes in the etiology of preeclampsia] diagnostic usage,unassigned 1,0 7.2.2.3 Pre-Eclampsia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16458353&form=6&db=m Marinobufagenin impairs first trimester cytotrophoblast differentiation. causal interaction,unassigned 4,0 7.2.2.3 Pre-Eclampsia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17127253&form=6&db=m Sodium regulation, sodium pump function and sodium pump inhibitors in uncomplicated pregnancy and preeclampsia. therapeutic application,unassigned 3,0 7.2.2.3 Pre-Eclampsia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17942287&form=6&db=m Endogenous sodium pump inhibitors, diabetes mellitus and preeclampsia Preliminary observations and a hypothesis. causal interaction,therapeutic application,unassigned 4,4,0 7.2.2.3 Pre-Eclampsia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19158804&form=6&db=m Erythrocyte sodium/potassium ATPase activity in severe preeclampsia. causal interaction,diagnostic usage,ongoing research,unassigned 4,2,2,0 7.2.2.3 Pre-Eclampsia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20959646&form=6&db=m Digibind Reverses Inhibition of Cellular rb+ Uptake Caused by Endogenous Sodium Pump Inhibitors Present in Serum and Placenta of Women With Preeclampsia. causal interaction,therapeutic application,unassigned 3,2,0 7.2.2.3 Pre-Eclampsia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21749548&form=6&db=m Digoxin Immune Fab Protects Endothelial Cells from Ouabain-Induced Barrier Injury. unassigned - 7.2.2.3 Pregnancy, Prolonged http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4249344&form=6&db=m [Accumulation of actomyosin and its adenosine triphosphatase activity in the muscle of cervix uteri in prolonged pregnancy] unassigned - 7.2.2.3 Pressure Ulcer http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21781462&form=6&db=m [Activity of adenosine triphosphatase and the expression of ryanodine receptor 1 mRNA in local tissue of pressure ulcer at early stage in gracilis of rats]. diagnostic usage,ongoing research,unassigned 2,3,0 7.2.2.3 Prostatic Hyperplasia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14025204&form=6&db=m [Enzymatic activities in human prostatic adenoma (leucine aminopeptidase, 5-nucleotidase, adenosine triphosphatase, lactic dehydrogenase, phosphohexoisomerase).] ongoing research,unassigned 3,0 7.2.2.3 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10487609&form=6&db=m Regulation of expression of Na+,K+-ATPase in androgen-dependent and androgen-independent prostate cancer. causal interaction,diagnostic usage,unassigned 2,1,0 7.2.2.3 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30107342&form=6&db=m Cytotoxicity of AMANTADIG - a semisynthetic digitoxigenin derivative - alone and in combination with docetaxel in human hormone-refractory prostate cancer cells and its effect on Na+/K+-ATPase inhibition. causal interaction,ongoing research,therapeutic application,unassigned 4,1,4,0 7.2.2.3 Protein-Energy Malnutrition http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=111257&form=6&db=m Oedema in protein energy malnutrition: the role of the sodium pump. unassigned - 7.2.2.3 Protein-Energy Malnutrition http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=147623&form=6&db=m Erythrocyte membrane Na+ and K+ activated adenosine triphosphatase in protein-calorie malnutrition. diagnostic usage,ongoing research,unassigned 1,2,0 7.2.2.3 Protein-Energy Malnutrition http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=231442&form=6&db=m Modified kinetics of erythrocyte membrane Na+-K+ adenosine triphosphatase in protein-energy malnutrition. unassigned - 7.2.2.3 Protein-Energy Malnutrition http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6123320&form=6&db=m Erythrocyte osmotic fragility in protein-energy malnutrition: cholesterol, phospholipid, and CA2+, Mg2+ adenosine triphosphatase. unassigned - 7.2.2.3 Pseudohypoaldosteronism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12030906&form=6&db=m Erythrocyte Na+,K+-ATPase and nasal potential in pseudohypoaldosteronism. unassigned - 7.2.2.3 Psoriasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4247926&form=6&db=m [Adenosine triphosphatase activity and Langerhans cells in psoriasis] ongoing research,unassigned 4,0 7.2.2.3 Pulmonary Arterial Hypertension http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24136331&form=6&db=m Pulmonary arterial hypertension in familial hemiplegic migraine with ATP1A2 channelopathy. unassigned - 7.2.2.3 Pulmonary Disease, Chronic Obstructive http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17257557&form=6&db=m [Reduced expression of the sarcoplasmic calcium pump SERCA2 in skeletal muscle from patients with chronic obstructive pulmonary disease and low body weight] causal interaction,diagnostic usage,ongoing research,unassigned 3,3,3,0 7.2.2.3 Pulmonary Disease, Chronic Obstructive http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22573150&form=6&db=m The heavy metal tolerant soil bacterium Achromobacter sp. AO22 contains a unique copper homeostasis locus and two mer operons. unassigned - 7.2.2.3 Pulmonary Edema http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1656777&form=6&db=m Upregulation of rat lung Na-K-ATPase during hyperoxic injury. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,3,0 7.2.2.3 Pulmonary Edema http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11045636&form=6&db=m Modulation of pulmonary NA+ pump gene expression during cold storage and reperfusion. causal interaction,diagnostic usage,therapeutic application,unassigned 4,3,4,0 7.2.2.3 Pulmonary Edema http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12682491&form=6&db=m Single dexamethasone injection increases alveolar fluid clearance in adult rats. therapeutic application,unassigned 1,0 7.2.2.3 Pulmonary Edema http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15668300&form=6&db=m Pulmonary edema clearance: juicing up the sodium pump. unassigned - 7.2.2.3 Pulmonary Sclerosing Hemangioma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2537067&form=6&db=m Sclerosing hemangioma of the lung. An immunohistochemical study of intermediate filaments and endothelial markers. diagnostic usage,ongoing research,unassigned 4,2,0 7.2.2.3 Pyelonephritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8016997&form=6&db=m [Membrane-destabilizing processes as the universal basis of inflammation] causal interaction,unassigned 3,0 7.2.2.3 Renal Insufficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1313528&form=6&db=m Reduction of erythrocyte (Na(+)-K+) ATPase activities in non-insulin-dependent diabetic patients with hyperkalemia. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,3,0 7.2.2.3 Renal Insufficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2074649&form=6&db=m Effects of acute and chronic uremia on active cation transport in rat myocardium. causal interaction,ongoing research,therapeutic application,unassigned 3,4,1,0 7.2.2.3 Renal Insufficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4010843&form=6&db=m Digoxin-like immunoreacting substance(s) in the serum of patients with chronic uremia. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,1,3,2 7.2.2.3 Renal Insufficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6216810&form=6&db=m Biochemical abnormalities of platelets in renal failure. Evidence for decreased platelet serotonin, adenosine diphosphate and Mg-dependent adenosine triphosphatase. causal interaction,diagnostic usage,ongoing research,unassigned 3,3,2,0 7.2.2.3 Renal Insufficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6265220&form=6&db=m Digoxin in the elderly and in renal failure. Contribution of erythrocyte 86-rubidium uptake tests. diagnostic usage,unassigned 4,0 7.2.2.3 Renal Insufficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9052901&form=6&db=m Sodium pump isoform specificity for the digitalis-like factor isolated from human peritoneal dialysate. diagnostic usage,ongoing research,therapeutic application,unassigned 1,2,1,0 7.2.2.3 Renal Insufficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9682917&form=6&db=m A labile sodium pump inhibitor from the peritoneal dialysate of hypertensive renal failure patients: estimates of potency. ongoing research,unassigned 2,0 7.2.2.3 Renal Insufficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11116125&form=6&db=m Application of supercritical fluid chromatography to characterize a labile digitalis-like factor. therapeutic application,unassigned 1,0 7.2.2.3 Renal Insufficiency, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=222070&form=6&db=m [Effect of hemodialysis on erythrocyte acetylcholinesterase and adenosine triphosphatase activity in chronic renal insufficiency] diagnostic usage,ongoing research,unassigned 4,3,0 7.2.2.3 Renal Insufficiency, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3028785&form=6&db=m Further biochemical characterization of an Na+ pump inhibitor purified from human urine. causal interaction,therapeutic application,unassigned 3,1,0 7.2.2.3 Renal Insufficiency, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4271421&form=6&db=m Decreased ouabain-sensitive adenosine triphosphatase activity in the erythrocyte membrame of patients with chronic renal disease. causal interaction,diagnostic usage,unassigned 2,2,0 7.2.2.3 Renal Insufficiency, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6255727&form=6&db=m Inhibition of Na+,K+-stimulated ATPase in the cochlea of the guinea pig. A potential cause of disturbed inner ear function in terminal renal failure. causal interaction,ongoing research,therapeutic application,unassigned 1,2,2,0 7.2.2.3 Renal Insufficiency, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17109139&form=6&db=m Ca2+-Mg2+-dependent ATP-ase activity and calcium homeostasis in children with chronic kidney disease. diagnostic usage,ongoing research,unassigned 2,3,0 7.2.2.3 Reperfusion Injury http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2143089&form=6&db=m [Activity of ectoenzymes of the heart breaking up ATP in the period of myocardial reperfusion after ischemia] causal interaction,therapeutic application,unassigned 1,2,0 7.2.2.3 Reperfusion Injury http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11045636&form=6&db=m Modulation of pulmonary NA+ pump gene expression during cold storage and reperfusion. causal interaction,diagnostic usage,therapeutic application,unassigned 4,3,4,0 7.2.2.3 Reperfusion Injury http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20130737&form=6&db=m Antidigoxin antiserum prevents endogenous digitalis-like compound-mediated reperfusion injury via modulating sodium pump isoform gene expression. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,4,3 7.2.2.3 Respiratory Distress Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18448505&form=6&db=m Regulation of alveolar epithelial function by hypoxia. diagnostic usage,unassigned 1,0 7.2.2.3 Respiratory Distress Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25004064&form=6&db=m Electroporation Mediated Gene Delivery of Na+,K+-ATPase and ENaC Subunits to the Lung Attenuates Acute Respiratory Distress Syndrome in a Two-Hit Porcine Model. ongoing research,unassigned 2,0 7.2.2.3 Retinitis Pigmentosa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11453454&form=6&db=m High mitochondrial DNA T8993G mutation (<90%) without typical features of Leigh's and NARP syndromes. causal interaction,unassigned 3,0 7.2.2.3 Rhabdomyolysis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8331362&form=6&db=m Exertional rhabdomyolysis in a patient with calcium adenosine triphosphatase deficiency. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,1,0 7.2.2.3 Rhabdomyolysis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18227802&form=6&db=m Altered fluid, electrolyte and mineral status in tropical disease, with an emphasis on malaria and leptospirosis. unassigned - 7.2.2.3 Rhabdomyosarcoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8386019&form=6&db=m Cholinergic stimulation of the Na+/K+ adenosine triphosphatase as revealed by microphysiometry. diagnostic usage,ongoing research,unassigned 3,3,0 7.2.2.3 Rhabdomyosarcoma, Alveolar http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3159641&form=6&db=m An evaluation of enzyme histochemistry in the diagnosis of childhood rhabdomyosarcoma. diagnostic usage,therapeutic application,unassigned 4,1,0 7.2.2.3 Rheumatoid Nodule http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6375915&form=6&db=m A combined immunohistological and histochemical analysis of lymphocyte and macrophage subpopulations in the rheumatoid nodule. ongoing research,unassigned 4,0 7.2.2.3 Rhinitis, Allergic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9087149&form=6&db=m Inhibition of the sodium, potassium adenosine triphosphatase enzyme in peripheral blood mononuclear cells of subjects with allergic rhinitis. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,4,4,2 7.2.2.3 Rhinitis, Allergic, Seasonal http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6211417&form=6&db=m Quercetin inhibition of the induction and function of cytotoxic T lymphocytes. ongoing research,unassigned 2,0 7.2.2.3 Sarcoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=145325&form=6&db=m An enzyme histochemical study of non-Hodgkin's lymphoma and allied disease. diagnostic usage,ongoing research,unassigned 3,3,0 7.2.2.3 Sarcoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3018708&form=6&db=m Adenosine triphosphatase activity of crystalline inclusions in alveolar soft part sarcoma. An ultrahistochemical study of a case. diagnostic usage,ongoing research,unassigned 3,2,0 7.2.2.3 Sarcoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4235234&form=6&db=m [Effect of dipin on the activity of water soluble adenosine triphosphatase in rats with sarcoma 45] ongoing research,unassigned 4,0 7.2.2.3 Sarcoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34069490&form=6&db=m Essential Oils, Pituranthos chloranthus and Teucrium ramosissimum, Chemosensitize Resistant Human Uterine Sarcoma MES-SA/Dx5 Cells to Doxorubicin by Inducing Apoptosis and Targeting P-Glycoprotein. ongoing research,therapeutic application,unassigned 1,1,0 7.2.2.3 Sarcoma 180 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=139308&form=6&db=m Enzymatic responses of transplanted tumour cells towards estrogen, progesterone and testosterone. ongoing research,unassigned 4,0 7.2.2.3 Sarcoma 180 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=923517&form=6&db=m Enzymatic responses of transplanted tumour cells towards estrogen, progesterone and testosterone. ongoing research,unassigned 4,0 7.2.2.3 Sarcoma 180 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14228524&form=6&db=m CYTOCHEMICAL LOCALIZATION OF ADENOSINE TRIPHOSPHATASE IN THE MITOTIC APPARATUS OF HELA AND SARCOMA 180 TISSUE CULTURE CELLS. ongoing research,therapeutic application,unassigned 4,1,0 7.2.2.3 Sarcoma, Alveolar Soft Part http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3018708&form=6&db=m Adenosine triphosphatase activity of crystalline inclusions in alveolar soft part sarcoma. An ultrahistochemical study of a case. diagnostic usage,ongoing research,unassigned 3,2,0 7.2.2.3 Sarcoma, Avian http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6260348&form=6&db=m Increased glucose uptake capacity of Rous-transformed cells and the relevance of deprivation derepression. causal interaction,unassigned 1,0 7.2.2.3 Sarcoma, Kaposi http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14243140&form=6&db=m HISTOCHEMISTRY OF KAPOSI'S SARCOMA. II. CHOLINESTERASES, MONOAMINE OXIDASE, AND ADENOSINE TRIPHOSPHATASE. unassigned - 7.2.2.3 Sarcoma, Synovial http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2580443&form=6&db=m Cellular differentiation of epithelioid sarcoma. An electron-microscopic, enzyme-histochemical, and immunohistochemical study. ongoing research,unassigned 3,0 7.2.2.3 Sarcoma, Yoshida http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4251851&form=6&db=m Increase of adenosine triphosphatase activity of Yoshida sarcoma cells in the process of acquiring resistance to alkylating agents. unassigned - 7.2.2.3 Scoliosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2460930&form=6&db=m Muscle spindles in the paraspinal musculature of patients with adolescent idiopathic scoliosis. ongoing research,unassigned 2,0 7.2.2.3 Seizures http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2550975&form=6&db=m Cortical Na+,K+-ATPase of immature rats following bicuculline-induced seizures. ongoing research,unassigned 1,0 7.2.2.3 Seizures http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2848701&form=6&db=m Reduced ouabain binding to erythrocytes in epilepsy--evidence for a membrane abnormality. diagnostic usage,ongoing research,unassigned 2,3,0 7.2.2.3 Seizures http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3004642&form=6&db=m The effect of vanadate on Na+,K+-ATPase activity of mouse cerebral cortex during bicuculline-induced seizures. causal interaction,ongoing research,unassigned 1,2,0 7.2.2.3 Seizures http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4263102&form=6&db=m Increased activity of the sodium-plus-potassium ion-stimulated adenosine triphosphatase in rat brain during electrically induced convulsions. unassigned - 7.2.2.3 Seizures http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12790888&form=6&db=m Intrastriatal methylmalonic acid administration induces convulsions and TBARS production, and alters Na+,K+-ATPase activity in the rat striatum and cerebral cortex. causal interaction,therapeutic application,unassigned 4,2,0 7.2.2.3 Seizures http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12953268&form=6&db=m Novel mutations in the Na+, K+-ATPase pump gene ATP1A2 associated with familial hemiplegic migraine and benign familial infantile convulsions. causal interaction,unassigned 3,0 7.2.2.3 Seizures http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15021241&form=6&db=m Genetics of the epilepsies. causal interaction,ongoing research,unassigned 3,1,0 7.2.2.3 Seizures http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15987881&form=6&db=m Mutation in the glutamate transporter EAAT1 causes episodic ataxia, hemiplegia, and seizures. ongoing research,therapeutic application,unassigned 3,1,0 7.2.2.3 Seizures http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16026932&form=6&db=m No evidence of ATP1A2 involvement in 12 multiplex Italian families with benign familial infantile seizures. causal interaction,unassigned 1,0 7.2.2.3 Seizures http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16116111&form=6&db=m Mutation in the glutamate transporter EAAT1 causes episodic ataxia, hemiplegia, and seizures. ongoing research,therapeutic application,unassigned 3,1,0 7.2.2.3 Seizures http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16516483&form=6&db=m GM1 ganglioside prevents seizures, Na+,K+-ATPase activity inhibition and oxidative stress induced by glutaric acid and pentylenetetrazole. causal interaction,therapeutic application,unassigned 4,3,0 7.2.2.3 Seizures http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16822249&form=6&db=m Linkage analysis and disease models in benign familial infantile seizures: a study of 16 families. causal interaction,ongoing research,unassigned 1,1,0 7.2.2.3 Seizures http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18080189&form=6&db=m Diphenyl diselenide-induced seizures in rat pups: possible interaction with glutamatergic system. unassigned - 7.2.2.3 Seizures http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18644608&form=6&db=m A novel de novo nonsense mutation in ATP1A2 associated with sporadic hemiplegic migraine and epileptic seizures. causal interaction,unassigned 2,0 7.2.2.3 Seizures http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19798568&form=6&db=m Lipoic Acid Alters delta-Aminolevulinic Dehydratase, Glutathione Peroxidase and Na+,K+-ATPase Activities and Glutathione-Reduced Levels in Rat Hippocampus After Pilocarpine-Induced Seizures. causal interaction,diagnostic usage,ongoing research,unassigned 1,2,1,0 7.2.2.3 Seizures http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23530735&form=6&db=m Treadmill exercise protects against pentylenetetrazol-induced seizures and oxidative stress after traumatic brain injury. causal interaction,therapeutic application,unassigned 3,4,0 7.2.2.3 Seizures http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24097848&form=6&db=m A Wide Clinical Phenotype Spectrum in Patients With ATP1A2 Mutations. causal interaction,ongoing research,unassigned 4,2,0 7.2.2.3 Seizures http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25476251&form=6&db=m Genome-wide screen for modifiers of Na + /K + ATPase alleles identifies critical genetic loci. causal interaction,therapeutic application,unassigned 3,1,0 7.2.2.3 Seizures http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25523819&form=6&db=m Knock-in mouse model of alternating hemiplegia of childhood: behavioral and electrophysiologic characterization. causal interaction,unassigned 3,0 7.2.2.3 Seizures http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27052298&form=6&db=m Relationship between susceptibility to DMCM-induced generalized motor convulsions and low-affinity [3H]-ouabain binding in membranes in rat brain. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,1,1,1 7.2.2.3 Seizures http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28465228&form=6&db=m Knockout of sodium pump ?3 subunit gene (Atp1a3(-/-)) results in perinatal seizure and defective respiratory rhythm generation. therapeutic application,unassigned 1,0 7.2.2.3 Seizures http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28595553&form=6&db=m Sulfur - Containing Amino Acids Homocysteine And Taurine In Seizures: Current State Of The Art. ongoing research,unassigned 2,0 7.2.2.3 Seizures http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31131006&form=6&db=m Assessment of neuropharmacological potential of low molecular weight components extracted from Rhinella schneideri toad poison. unassigned - 7.2.2.3 Seizures http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31766058&form=6&db=m Early Treatment in Acute Severe Encephalopathy Caused by ATP1A2 Mutation of Familial Hemiplegic Migraine Type 2: Case Report and Literature Review. causal interaction,therapeutic application,unassigned 4,4,0 7.2.2.3 Seizures http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33578253&form=6&db=m A novel ATP1A2 variant associated with severe stepwise regression, hemiplegia, epilepsy and movement disorders in two unrelated patients. ongoing research,therapeutic application,unassigned 1,1,0 7.2.2.3 Seizures, Febrile http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19874388&form=6&db=m Familial hemiplegic migraine is associated with febrile seizures in an FHM2 family with a novel de novo ATP1A2 mutation. causal interaction,unassigned 4,0 7.2.2.3 Seizures, Febrile http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28527083&form=6&db=m Shared mechanisms of epilepsy, migraine and affective disorders. causal interaction,unassigned 4,0 7.2.2.3 Sepsis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8911258&form=6&db=m Glucocorticoid receptor antagonism by mifepristone alters phosphocreatine breakdown during sepsis. therapeutic application,unassigned 1,0 7.2.2.3 Sepsis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11146788&form=6&db=m Sepsis increases the plasma membrane content of alpha1 and alpha2 isoforms of Na+-K+ adenosine triphosphatase in rat skeletal muscle. causal interaction,ongoing research,unassigned 2,2,0 7.2.2.3 Sepsis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28765908&form=6&db=m SERCA1 attenuates diaphragm relaxation and uptake rate of SERCA in rats with acute sepsis. causal interaction,ongoing research,therapeutic application,unassigned 3,3,3,0 7.2.2.3 Severe Acute Respiratory Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32964796&form=6&db=m Coronavirus interactions with the cellular autophagy machinery. ongoing research,unassigned 1,0 7.2.2.3 Shock, Septic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3013453&form=6&db=m Myocardial sodium pump activity in endotoxin shock. diagnostic usage,unassigned 1,0 7.2.2.3 Sjogren's Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9273365&form=6&db=m An immunocytochemical study of H+ ATPase in kidney transplant rejection. causal interaction,diagnostic usage,unassigned 1,3,0 7.2.2.3 Sleep Apnea, Obstructive http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23826169&form=6&db=m Association between uric acid levels and obstructive sleep apnea syndrome in a large epidemiological sample. unassigned - 7.2.2.3 Sleep Apnea, Obstructive http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26102761&form=6&db=m 2B.03: URIC ACID LEVELS RELATED TO OBSTRUCTIVE SLEEP APNEA SYNDROME IN PATIENTS WITH HYPERTENSION FROM XINJIANG OF CHINA. unassigned - 7.2.2.3 Sleep Apnea, Obstructive http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32441247&form=6&db=m Muscle type of palatopharyngeal muscle in children with severe obstructive sleep apnea. diagnostic usage,ongoing research,unassigned 3,2,0 7.2.2.3 Sleep Deprivation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10737614&form=6&db=m Norepinephrine-stimulated increase in Na+, K+-ATPase activity in the rat brain is mediated through alpha1A-adrenoceptor possibly by dephosphorylation of the enzyme. causal interaction,unassigned 1,0 7.2.2.3 Sleep Deprivation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26054600&form=6&db=m Glial-specific gene alterations associated with manic behaviors. causal interaction,ongoing research,therapeutic application,unassigned 4,3,1,0 7.2.2.3 Sleep Deprivation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32360816&form=6&db=m Na+/K+-ATPase and lipid peroxidation in forebrain cortex and hippocampus of sleep-deprived rats treated with therapeutic lithium concentration for different periods of time. ongoing research,unassigned 4,0 7.2.2.3 Spastic Paraplegia, Hereditary http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14732620&form=6&db=m Three novel mutations of the spastin gene in Chinese patients with hereditary spastic paraplegia. causal interaction,unassigned 4,0 7.2.2.3 Spastic Paraplegia, Hereditary http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15716377&form=6&db=m Linking axonal degeneration to microtubule remodeling by Spastin-mediated microtubule severing. unassigned - 7.2.2.3 Spinal Cord Injuries http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14694496&form=6&db=m Na+,K+-ATPase concentration and fiber type distribution after spinal cord injury. ongoing research,unassigned 4,0 7.2.2.3 Spinal Cord Injuries http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22275761&form=6&db=m Influence of chronic and acute spinal cord injury on skeletal muscle Na+/K+-ATPase and phospholemman expression in humans. causal interaction,ongoing research,unassigned 4,4,0 7.2.2.3 Spinal Cord Injuries http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28886701&form=6&db=m The loss-of-function disease-mutation G301R in the Na(+)/K(+)-ATPase ?2 isoform decreases lesion volume and improves functional outcome after acute spinal cord injury in mice. ongoing research,unassigned 4,0 7.2.2.3 Squamous Cell Carcinoma of Head and Neck http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12509969&form=6&db=m Expression of copper-transporting P-type adenosine triphosphatase (ATP7B) as a chemoresistance marker in human oral squamous cell carcinoma treated with cisplatin. diagnostic usage,ongoing research,therapeutic application,unassigned 2,4,1,0 7.2.2.3 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2847592&form=6&db=m Effects of starvation, feeding, and time of day on the activity of proton transport adenosine triphosphatase in the parietal cells of the mouse gastric glands. diagnostic usage,ongoing research,unassigned 1,4,0 7.2.2.3 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6260348&form=6&db=m Increased glucose uptake capacity of Rous-transformed cells and the relevance of deprivation derepression. causal interaction,unassigned 1,0 7.2.2.3 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10510283&form=6&db=m Sodium chloride-induced volume changes of freshwater cyanobacterium Synechococcus sp. PCC 7942 cells can be probed by chlorophyll a fluorescence. unassigned - 7.2.2.3 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12115059&form=6&db=m A chimeric Anabaena/ Escherichia coli KdpD protein (Anacoli KdpD) functionally interacts with E. coli KdpE and activates kdp expression in E. coli. therapeutic application,unassigned 1,0 7.2.2.3 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17337637&form=6&db=m Mg2+ deprivation elicits rapid Ca2+ uptake and activates Ca2+/calcineurin signaling in Saccharomyces cerevisiae. unassigned - 7.2.2.3 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23789400&form=6&db=m [Na,K-ATPase activity of erythrocytes of rats during prolonged starvation]. causal interaction,diagnostic usage,ongoing research,unassigned 3,2,2,0 7.2.2.3 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26070686&form=6&db=m Pma1 is an alkali/alkaline earth metal cation ATPase that preferentially transports Na(+) and K(+) across the Mycobacterium smegmatis plasma membrane. therapeutic application,unassigned 1,0 7.2.2.3 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31037366&form=6&db=m Functional analysis of McSnRK1 (SNF1-related protein kinase 1) in regulating Na/K homeostasis in transgenic cultured cells and roots of halophyte Mesembryanthemum crystallinum. therapeutic application,unassigned 1,0 7.2.2.3 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31941841&form=6&db=m Interaction between the autophagy protein Beclin 1 and Na+,K+-ATPase during starvation, exercise, and ischemia. therapeutic application,unassigned 1,0 7.2.2.3 Status Epilepticus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=153226&form=6&db=m Enzyme histochemistry of the rat hippocampus during experimental status epilepticus. diagnostic usage,ongoing research,unassigned 1,3,0 7.2.2.3 Status Epilepticus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21475241&form=6&db=m The role of spreading depression, spreading depolarization and spreading ischemia in neurological disease. therapeutic application,unassigned 2,0 7.2.2.3 Status Epilepticus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25311690&form=6&db=m Long-term decrease in Na+,K+-ATPase activity after pilocarpine-induced status epilepticus is associated with nitration of its alpha subunit. causal interaction,diagnostic usage,unassigned 1,1,0 7.2.2.3 Stomach Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1830824&form=6&db=m Differential sensitivity of human gastric cancer ATPase and normal gastric mucosa ATPase to the synthetic mammalian lignan analogue 2,3-dibenzylbutane-1,4-diol (hattalin). diagnostic usage,ongoing research,unassigned 1,4,0 7.2.2.3 Stomach Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25202402&form=6&db=m Rabeprazole exhibits antiproliferative effects on human gastric cancer cell lines. diagnostic usage,therapeutic application,unassigned 1,1,0 7.2.2.3 Stomach Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34251542&form=6&db=m The expression of the alpha1 subunit of Na+/K+-ATPase is related to tumor development and clinical outcomes in gastric cancer. causal interaction,diagnostic usage,ongoing research,unassigned 4,2,4,0 7.2.2.3 Stomach Ulcer http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33025593&form=6&db=m Potassium bromate cytotoxicity in the Wister rat model of chronic gastric ulcers: Possible reversal by protocatechuic acid. causal interaction,unassigned 1,0 7.2.2.3 Stroke http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15142663&form=6&db=m Marinobufagenin may mediate the impact of salty diets on left ventricular hypertrophy by disrupting the protective function of coronary microvascular endothelium. unassigned - 7.2.2.3 Stroke http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15694707&form=6&db=m Marinobufagenin may mediate the impact of salty diets on left ventricular hypertrophy by disrupting the protective function of coronary microvascular endothelium. unassigned - 7.2.2.3 Stroke http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23459313&form=6&db=m Polymorphisms in migraine-associated gene, atp1a2, and ischemic stroke risk in a biracial population: the genetics of early onset stroke study. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,2,2,1 7.2.2.3 Stroke http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24396618&form=6&db=m Sporadic Hemiplegic Migraine with ATP1A2 and Prothrombin Gene Mutations. causal interaction,unassigned 4,0 7.2.2.3 Stroke http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34148020&form=6&db=m Bone Marrow Mononuclear Cells Transplantation and Training Increased Transplantation of Energy Source Transporters in Chronic Stroke. diagnostic usage,ongoing research,unassigned 3,2,0 7.2.2.3 Tachycardia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31527358&form=6&db=m [Cancer cell-specific functional relation between Na+,K+-ATPase and volume-regulated anion channel]. causal interaction,therapeutic application,unassigned 3,4,0 7.2.2.3 Talipes Cavus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29305691&form=6&db=m The CAPOS mutation in ATP1A3 alters Na/K-ATPase function and results in auditory neuropathy which has implications for management. causal interaction,unassigned 2,0 7.2.2.3 Talipes Cavus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30409907&form=6&db=m Functional consequences of the CAPOS mutation E818K of Na+,K+-ATPase. unassigned - 7.2.2.3 Tangier Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6152683&form=6&db=m Endoneurial ATPase activity in Tangier disease and other peripheral neuropathies. causal interaction,diagnostic usage,ongoing research,unassigned 1,4,2,0 7.2.2.3 Teratocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=192083&form=6&db=m Ultrastructural localization of membrane phosphatases in teratocarcinoma and early embryos. causal interaction,diagnostic usage,ongoing research,unassigned 1,1,4,0 7.2.2.3 Teratocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10198212&form=6&db=m Cloning, expression, and chromosomal mapping of a human ATPase II gene, member of the third subfamily of P-type ATPases and orthologous to the presumed bovine and murine aminophospholipid translocase. unassigned - 7.2.2.3 Tetanus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=158400&form=6&db=m Muscle and serum adenosine triphosphatase in patients suffering from tetanus. causal interaction,diagnostic usage,ongoing research,unassigned 3,4,3,0 7.2.2.3 Tetanus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=843926&form=6&db=m Post-tetanic spontaneous spike activity in rat sympathetic neurons exposed to low potassium ion concentration. causal interaction,unassigned 3,0 7.2.2.3 Tetanus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8169833&form=6&db=m Inhibition of vacuolar adenosine triphosphatase antagonizes the effects of clostridial neurotoxins but not phospholipase A2 neurotoxins. therapeutic application,unassigned 1,0 7.2.2.3 Thyroid Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2987290&form=6&db=m Erythrocyte sodium/potassium adenosine triphosphatase in thyroid disease and nonthyroidal illness. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,4,0 7.2.2.3 Thyroid Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3028698&form=6&db=m Ion flux and Na+,K+-ATPase activity of erythrocytes and leucocytes in thyroid disease. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,1,1,1 7.2.2.3 Thyrotoxicosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=152679&form=6&db=m Stimulation of cardiac myosin adenosine triphosphatase in thyrotoxicosis. therapeutic application,unassigned 2,0 7.2.2.3 Trauma, Nervous System http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18184478&form=6&db=m The Na, K-ATPase alpha3-isoform specifically localizes in the Schmidt-Lanterman incisures of human nerve. ongoing research,unassigned 4,0 7.2.2.3 Tremor http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11926533&form=6&db=m Effects of L-phenylalanine on acetylcholinesterase and Na+,K+-ATPase activities in suckling rat frontal cortex, hippocampus and hypothalamus. causal interaction,unassigned 3,0 7.2.2.3 Tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10477555&form=6&db=m Mycobacterium tuberculosis expresses a novel pH-dependent divalent cation transporter belonging to the Nramp family. ongoing research,unassigned 2,0 7.2.2.3 Tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25967101&form=6&db=m CtpA, a putative Mycobacterium tuberculosis P-type ATPase, is stimulated by copper (I) in the mycobacterial plasma membrane. diagnostic usage,ongoing research,unassigned 2,2,0 7.2.2.3 Tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26070686&form=6&db=m Pma1 is an alkali/alkaline earth metal cation ATPase that preferentially transports Na(+) and K(+) across the Mycobacterium smegmatis plasma membrane. therapeutic application,unassigned 1,0 7.2.2.3 Tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31788573&form=6&db=m The P-type ATPase CtpF is a plasma membrane transporter mediating calcium efflux in Mycobacterium tuberculosis cells. ongoing research,unassigned 3,0 7.2.2.3 Tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32054527&form=6&db=m CtpB is a plasma membrane copper (I) transporting P-type ATPase of Mycobacterium tuberculosis. ongoing research,unassigned 3,0 7.2.2.3 Uremia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=707352&form=6&db=m Zinc and the sodium pump in uremia. unassigned - 7.2.2.3 Uremia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1231923&form=6&db=m Arginase activity of human erythrocyte ghosts in uremia. ongoing research,unassigned 2,0 7.2.2.3 Uremia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1323635&form=6&db=m An Na, K ATPase inhibitor from ultrafiltrate obtained by hemodialysis of patients with uremia. diagnostic usage,therapeutic application,unassigned 3,2,0 7.2.2.3 Uremia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1661300&form=6&db=m Effect of chronic renal failure on Na,K-ATPase alpha 1 and alpha 2 mRNA transcription in rat skeletal muscle. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,4,1 7.2.2.3 Uremia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2074649&form=6&db=m Effects of acute and chronic uremia on active cation transport in rat myocardium. causal interaction,ongoing research,therapeutic application,unassigned 3,4,1,0 7.2.2.3 Uremia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25783847&form=6&db=m Intratympanic steroid injection as a first-line therapy in uremia patients with sudden sensorineural hearing loss. causal interaction,unassigned 3,0 7.2.2.3 Urinary Bladder Neck Obstruction http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11992100&form=6&db=m Enhanced force generation by corpus cavernosum smooth muscle in rabbits with partial bladder outlet obstruction. unassigned - 7.2.2.3 Urinary Bladder Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30127995&form=6&db=m Bufalin induced apoptosis of bladder carcinoma cells through the inactivation of Na+K+-ATPase. ongoing research,therapeutic application,unassigned 4,1,0 7.2.2.3 Uterine Cervical Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4221963&form=6&db=m [Histoenzymatic studies on the behavior of succinic acid dehydrogenase, NADH-2-tetrazolium reductase, adenosine triphosphatase and alkaline phosphatase in cases of uterine cervix cancer] unassigned - 7.2.2.3 Vascular System Injuries http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20956482&form=6&db=m Perivascular Delivery of Blebbistatin Reduces Neointimal Hyperplasia Following Carotid Injury in the Mouse. ongoing research,unassigned 4,0 7.2.2.3 Ventricular Fibrillation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=139466&form=6&db=m Digitalis toxicity: lack of marked effect on brain na+,k+-adenosine triphosphatase in the cat. diagnostic usage,ongoing research,unassigned 3,3,0 7.2.2.3 Vertigo http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16866717&form=6&db=m Migrainous vertigo: mutation analysis of the candidate genes CACNA1A, ATP1A2, SCN1A, and CACNB4. causal interaction,therapeutic application,unassigned 2,1,0 7.2.2.3 Vibrio Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15813866&form=6&db=m Evidence for disruption of Na(+)-K(+)-ATPase and hsp70 during vibriosis of sea bream, Sparus (=Rhabdosargus) sarba ForsskÃ¥l. causal interaction,diagnostic usage,unassigned 1,1,0 7.2.2.3 Virus Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6320528&form=6&db=m Alterations in monovalent cation transport in Sindbis virus-infected chick cells. diagnostic usage,therapeutic application,unassigned 3,1,0 7.2.2.3 Virus Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23876457&form=6&db=m Glycolytic control of vacuolar-type ATPase activity: A mechanism to regulate influenza viral infection. causal interaction,diagnostic usage,unassigned 4,1,0 7.2.2.3 Visna http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=233847&form=6&db=m Adenosine triphosphatase activity during fusion of cultured sheep choroid plexus cells induced by either visna virus or polyethylene glycol. ongoing research,unassigned 3,0 7.2.2.3 Werner Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12904570&form=6&db=m Diverse dealings of the Werner helicase/nuclease. unassigned - 7.2.2.3 Whooping Cough http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1764450&form=6&db=m The use of the potential-sensitive fluorescent probe bisoxonol in mast cells. unassigned - 7.2.2.3 Whooping Cough http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2844756&form=6&db=m Colony-stimulating factor 1-induced Na+ influx into human monocytes involves activation of a pertussis toxin-sensitive GTP-binding protein. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,2,2,1 7.2.2.3 Whooping Cough http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9496347&form=6&db=m Seminal fluid factor increases the resistance of the tight junctional complex of cultured human cervical epithelium CaSki cells. therapeutic application,unassigned 4,0 7.2.2.3 Whooping Cough http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9607407&form=6&db=m Angiotensin II AT1 receptor/signaling mechanisms in the biphasic effect of the peptide on proximal tubular Na+,K+-ATPase. ongoing research,therapeutic application,unassigned 3,2,0 7.2.2.3 Whooping Cough http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11589511&form=6&db=m Salt intake and intestinal dopaminergic activity in adult and old Fischer 344 rats. ongoing research,unassigned 1,0 7.2.2.3 Wolfram Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17947299&form=6&db=m Sodium-potassium ATPase 1 subunit is a molecular partner of Wolframin, an endoplasmic reticulum protein involved in ER stress. causal interaction,therapeutic application,unassigned 3,1,0 7.2.2.3 Wound Infection http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2852050&form=6&db=m Changes in erythrocyte membranes in burned rabbits. unassigned - 7.2.2.3 Yellow Fever http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19048614&form=6&db=m Strong alkalinization in the anterior midgut of larval yellow fever mosquitoes (Aedes aegypti): involvement of luminal Na+/K+-ATPase. unassigned - 7.2.2.3 Zenker Diverticulum http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12126011&form=6&db=m Morphology of the cricopharyngeal muscle in Zenker and control specimens. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,2,3,1 7.2.2.3 Zika Virus Infection http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32669655&form=6&db=m Inhibition of Na+/K+ ATPase blocks Zika virus infection in mice. causal interaction,therapeutic application,unassigned 4,4,0 7.2.2.3 Zollinger-Ellison Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1553942&form=6&db=m Fulminant hepatic failure related to omeprazole. unassigned -