3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6468738&form=6&db=m Hyperargininemia: the rat as a model for the human disease and the comparative response to enzyme replacement therapy with free arginase and arginase-loaded erythrocytes in vivo. diagnostic usage,ongoing research,therapeutic application,unassigned 2,4,3,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6729810&form=6&db=m A successful trial of enzyme replacement therapy in a case of argininemia. causal interaction,unassigned 3,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6796772&form=6&db=m Urinary pyrimidine excretion in arginase deficiency. causal interaction,diagnostic usage,therapeutic application,unassigned 3,2,1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6820432&form=6&db=m Treatment of hyperargininaemia due to arginase deficiency with a chemically defined diet. therapeutic application,unassigned 4,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7159597&form=6&db=m Polyamine dependence of Chinese hamster ovary cells in serum-free culture is due to deficient arginase activity. ongoing research,unassigned 1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7361766&form=6&db=m Properties of fetal and adult red blood cell arginase: a possible prenatal diagnostic test for arginase deficiency. causal interaction,diagnostic usage,ongoing research,unassigned 1,2,3,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7389092&form=6&db=m Fluorometric micromethod for determination of arginase activity in dried blood spots on filter paper. causal interaction,diagnostic usage,therapeutic application,unassigned 3,3,2,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7717428&form=6&db=m Prenatal diagnosis of the urea cycle diseases: a survey of the European cases. causal interaction,diagnostic usage,unassigned 2,3,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7967487&form=6&db=m Arginase deficiency presenting with convulsions. unassigned - 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8127062&form=6&db=m Arginase deficiency in two brothers. therapeutic application,unassigned 1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8454280&form=6&db=m Arginase deficiency manifesting delayed clinical sequelae and induction of a kidney arginase isozyme. causal interaction,unassigned 4,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8474825&form=6&db=m Arginase deficiency presenting as cerebral palsy. causal interaction,diagnostic usage,therapeutic application,unassigned 4,4,1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8777806&form=6&db=m [A case of complicated form of hereditary spastic paraplegia associated with hypoplasia of the corpus callosum and cataracta] causal interaction,unassigned 3,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8902193&form=6&db=m Loss of function mutations in conserved regions of the human arginase I gene. unassigned - 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9131018&form=6&db=m Delivery of cytosolic liver arginase into the mitochondrial matrix space: a possible novel site for gene replacement therapy. unassigned - 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9295913&form=6&db=m [Proposal for a diet treatment in arginase deficiency] therapeutic application,unassigned 4,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9590022&form=6&db=m [Arginase deficiency] unassigned - 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9686347&form=6&db=m The human arginases and arginase deficiency. ongoing research,unassigned 3,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9762606&form=6&db=m Adult-onset arginase deficiency. unassigned - 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10771848&form=6&db=m Arginase deficiency. causal interaction,unassigned 3,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10947208&form=6&db=m Arginase deficiency presenting with cerebral oedema and failure to thrive. unassigned - 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11148548&form=6&db=m The nutritional management of urea cycle disorders. causal interaction,diagnostic usage,unassigned 1,3,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11154268&form=6&db=m Generation of a mouse model for arginase II deficiency by targeted disruption of the arginase II gene. causal interaction,therapeutic application,unassigned 2,1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11746885&form=6&db=m Analysis of amino acids as formamidene butyl esters by electrospray ionization tandem mass spectrometry. diagnostic usage,unassigned 1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12052859&form=6&db=m Mouse model for human arginase deficiency. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,4,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12640389&form=6&db=m Arginase deficiency with lethal neonatal expression: evidence for the glutamine hypothesis of cerebral edema. causal interaction,unassigned 1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14605507&form=6&db=m Prenatal diagnosis for arginase deficiency: a case study. causal interaction,diagnostic usage,therapeutic application,unassigned 4,4,3,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15164414&form=6&db=m Genetic approach to prenatal diagnosis in urea cycle defects. causal interaction,unassigned 4,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15465784&form=6&db=m Clinical consequences of urea cycle enzyme deficiencies and potential links to arginine and nitric oxide metabolism. causal interaction,unassigned 4,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15546957&form=6&db=m Arginase I is constitutively expressed in human granulocytes and participates in fungicidal activity. causal interaction,unassigned 4,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15565656&form=6&db=m Prenatal diagnosis for arginase deficiency by second-trimester fetal erythrocyte arginase assay and first-trimester ARG1 mutation analysis. causal interaction,diagnostic usage,therapeutic application,unassigned 4,4,1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15694174&form=6&db=m Hyperargininemia due to liver arginase deficiency. causal interaction,therapeutic application,unassigned 4,1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15798789&form=6&db=m Autistic-like findings associated with a urea cycle disorder in a 4-year-old girl. causal interaction,diagnostic usage,unassigned 1,1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16233191&form=6&db=m Different missense mutations in PDR1 and PDR3 genes from clotrimazole-resistant sake yeast are responsible for pleiotropic drug resistance and improved fermentative activity. causal interaction,diagnostic usage,unassigned 3,3,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16602094&form=6&db=m Clinical, biochemical, and molecular spectrum of hyperargininemia due to arginase I deficiency. causal interaction,diagnostic usage,unassigned 4,3,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16963300&form=6&db=m A patient with arginase deficiency and episodic hyperammonemia successfully treated with menses cessation. therapeutic application,unassigned 3,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17098461&form=6&db=m Ornithine transcarbamylase and arginase I deficiency are responsible for diminished urea cycle function in the human hepatoblastoma cell line HepG2. causal interaction,unassigned 4,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17513443&form=6&db=m Orotic acid excretion and arginine metabolism. causal interaction,unassigned 4,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17513445&form=6&db=m Biomarkers identified in inborn errors for lysine, arginine, and ornithine. causal interaction,unassigned 4,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17997338&form=6&db=m Increased plasma and tissue guanidino compounds in a mouse model of hyperargininemia. causal interaction,therapeutic application,unassigned 4,1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18950360&form=6&db=m Anesthesia in a patient with arginase deficiency: implications and management. causal interaction,therapeutic application,unassigned 3,2,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19052914&form=6&db=m Amino acids in CSF and plasma in hyperammonaemic coma due to arginase1 deficiency. causal interaction,unassigned 4,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19367256&form=6&db=m Short-term Correction of Arginase Deficiency in a Neonatal Murine Model With a Helper-dependent Adenoviral Vector. ongoing research,therapeutic application,unassigned 1,1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19486531&form=6&db=m Bone marrow cell derived arginase I is the major source of allergen-induced lung arginase but is not required for airway hyperresponsiveness, remodeling and lung inflammatory responses in mice. causal interaction,unassigned 4,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19936428&form=6&db=m A novel mutation in ARG1 gene is responsible for arginase deficiency in an Asian family. causal interaction,unassigned 4,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20004862&form=6&db=m Diffusion tensor imaging in arginase deficiency reveals damage to corticospinal tracts. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20304692&form=6&db=m Creatine metabolism and the urea cycle. causal interaction,diagnostic usage,unassigned 4,1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20372170&form=6&db=m Impact of arginase II on CBF in experimental cortical impact injury in mice using MRI. therapeutic application,unassigned 1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20456883&form=6&db=m A long-term survival case of arginase deficiency with severe multicystic white matter and compound mutations. diagnostic usage,unassigned 1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21229317&form=6&db=m Neonatal cholestasis: an uncommon presentation of hyperargininemia. causal interaction,therapeutic application,unassigned 3,3,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21585399&form=6&db=m Arginase-1-expressing macrophages are dispensable for resistance to infection with the gastrointestinal helminth Trichuris muris. ongoing research,unassigned 3,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21802329&form=6&db=m Arginase I deficiency: Severe infantile presentation with hyperammonemia: More common than reported? causal interaction,unassigned 3,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22760543&form=6&db=m Long-term Survival of the Juvenile Lethal Arginase-deficient Mouse With AAV Gene Therapy. causal interaction,ongoing research,therapeutic application,unassigned 3,1,4,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22964440&form=6&db=m Arginase deficiency with new phenotype and a novel mutation: contemporary summary. causal interaction,diagnostic usage,ongoing research,unassigned 4,2,2,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22971419&form=6&db=m Recurrent unexplained hyperammonemia in an adolescent with arginase deficiency. causal interaction,ongoing research,therapeutic application,unassigned 1,2,2,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23388701&form=6&db=m AAV-based gene therapy prevents neuropathology and results in normal cognitive development in the hyperargininemic mouse. causal interaction,unassigned 1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23859858&form=6&db=m Five novel mutations in ARG1 gene in Chinese patients of argininemia. causal interaction,unassigned 3,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23920045&form=6&db=m Lethal phenotype in conditional late-onset arginase 1 deficiency in the mouse. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,1,1 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24224027&form=6&db=m Inducible arginase 1 deficiency in mice leads to hyperargininemia and altered amino acid metabolism. causal interaction,ongoing research,unassigned 4,3,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24465919&form=6&db=m Arginase-1 Deficiency Regulates Arginine Concentrations and NOS2-Mediated NO Production during Endotoxemia. therapeutic application,unassigned 1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24814679&form=6&db=m Treatment of arginase deficiency revisited: guanidinoacetate as a therapeutic target and biomarker for therapeutic monitoring. causal interaction,therapeutic application,unassigned 4,4,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24888478&form=6&db=m Myocyte-mediated Arginase Expression Controls Hyperargininemia but not Hyperammonemia in Arginase-deficient Mice. causal interaction,ongoing research,unassigned 2,2,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25474440&form=6&db=m Minimal ureagenesis is necessary for survival in the murine model of hyperargininemia treated by AAV-based gene therapy. causal interaction,therapeutic application,unassigned 4,4,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25611620&form=6&db=m Anesthetic management of a patient with arginase deficiency undergoing liver transplantation. therapeutic application,unassigned 1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25938595&form=6&db=m Strategies to rescue the consequences of inducible arginase-1 deficiency in mice. causal interaction,therapeutic application,unassigned 4,1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26123990&form=6&db=m Hyperargininemia due to arginase I deficiency: the original patients and their natural history, and a review of the literature. causal interaction,therapeutic application,unassigned 4,1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26310552&form=6&db=m [Seven patients of argininemia with spastic tetraplegia as the first and major symptom and prenatal diagnosis of two fetuses with high risk]. unassigned - 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26358771&form=6&db=m Human recombinant arginase enzyme reduces plasma arginine in mouse models of arginase deficiency. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,4 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26467175&form=6&db=m Arginase-1 deficiency. causal interaction,unassigned 4,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27038030&form=6&db=m Clinical phenotype, biochemical profile, and treatment in 19 patients with arginase 1 deficiency. causal interaction,diagnostic usage,therapeutic application,unassigned 4,3,1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27215558&form=6&db=m Improving long term outcomes in urea cycle disorders-report from the Urea Cycle Disorders Consortium. causal interaction,unassigned 4,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27335400&form=6&db=m Rescue of the Functional Alterations of Motor Cortical Circuits in Arginase Deficiency by Neonatal Gene Therapy. causal interaction,unassigned 4,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27570396&form=6&db=m Late onset arginase deficiency presenting with encephalopathy and midbrain hyperintensity. therapeutic application,unassigned 1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27663197&form=6&db=m Efficacy and safety of i.v. sodium benzoate in urea cycle disorders: a multicentre retrospective study. causal interaction,unassigned 2,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27761413&form=6&db=m Liver-specific knockout of arginase-1 leads to a profound phenotype similar to inducible whole body arginase-1 deficiency. causal interaction,diagnostic usage,unassigned 2,3,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27898091&form=6&db=m Restoring Ureagenesis in Hepatocytes by CRISPR/Cas9-mediated Genomic Addition to Arginase-deficient Induced Pluripotent Stem Cells. causal interaction,therapeutic application,unassigned 2,1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27998825&form=6&db=m Hematopoietic arginase 1 deficiency results in decreased leukocytosis and increased foam cell formation but does not affect atherosclerosis. causal interaction,unassigned 4,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28515179&form=6&db=m Arginase-2 mediates renal ischemia-reperfusion injury. causal interaction,ongoing research,unassigned 1,4,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28566761&form=6&db=m Proof-of-Concept Gene Editing for the Murine Model of Inducible Arginase-1 Deficiency. causal interaction,therapeutic application,unassigned 4,1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28659245&form=6&db=m Newborn screening for hyperargininemia due to arginase 1 deficiency. causal interaction,diagnostic usage,unassigned 4,1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28747341&form=6&db=m Arginase1 Deficiency in Monocytes/Macrophages Upregulates Inducible Nitric Oxide Synthase To Promote Cutaneous Contact Hypersensitivity. causal interaction,ongoing research,unassigned 4,4,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29187023&form=6&db=m Biopsy-proven Hepatocellular Carcinoma in a 53-year-old Woman With Arginase Deficiency. causal interaction,therapeutic application,unassigned 2,1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29423830&form=6&db=m Biochemical markers and neuropsychological functioning in distal urea cycle disorders. causal interaction,unassigned 4,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29478971&form=6&db=m Kidney Mass Reduction Leads to l-Arginine Metabolism-Dependent Blood Pressure Increase in Mice. causal interaction,diagnostic usage,unassigned 1,3,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29724658&form=6&db=m Human hepatocyte transplantation corrects the inherited metabolic liver disorder arginase deficiency in mice. causal interaction,ongoing research,therapeutic application,unassigned 3,4,4,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29948653&form=6&db=m Early liver transplantation in neonatal-onset and moderate urea cycle disorders may lead to normal neurodevelopment. causal interaction,unassigned 4,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29961498&form=6&db=m "Cerebral Palsy" in a Patient With Arginase Deficiency. causal interaction,diagnostic usage,unassigned 3,4,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30294546&form=6&db=m The first pediatric case of glucagon receptor defect due to biallelic mutations in GCGR is identified by newborn screening of elevated arginine. therapeutic application,unassigned 1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30670878&form=6&db=m Untargeted metabolomic profiling reveals multiple pathway perturbations and new clinical biomarkers in urea cycle disorders. causal interaction,diagnostic usage,unassigned 4,3,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30671984&form=6&db=m A new metabolic disorder in human cationic amino acid transporter-2 that mimics arginase 1 deficiency in newborn screening. causal interaction,unassigned 4,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31484827&form=6&db=m Hepatic arginase deficiency fosters dysmyelination during postnatal CNS development. causal interaction,ongoing research,therapeutic application,unassigned 4,1,1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31501335&form=6&db=m Lipid nanoparticle-targeted mRNA therapy as a treatment for the inherited metabolic liver disorder arginase deficiency. causal interaction,therapeutic application,unassigned 4,4,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31604595&form=6&db=m Sodium phenylbutyrate improved the clinical state in an adult patient with arginase 1 deficiency. causal interaction,diagnostic usage,unassigned 2,1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31649772&form=6&db=m Arginase Deficiency Presenting as Acute Encephalopathy. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,2,3,1 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32025996&form=6&db=m Anesthetic management of a pediatric patient with arginase-1 deficiency undergoing strabismus operation: a case report. causal interaction,therapeutic application,unassigned 4,1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32580855&form=6&db=m Hyperargininemic Encephalopathy with Unique Clinical Presentation and Novel Genetic Mutations. causal interaction,ongoing research,unassigned 4,1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32769929&form=6&db=m A novel compound heterozygous mutation in the arginase-1 gene identified in a Chinese patient with argininemia: A case report. causal interaction,therapeutic application,unassigned 4,1,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32872442&form=6&db=m Metabolic Serendipities of Expanded Newborn Screening. causal interaction,unassigned 3,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33325055&form=6&db=m Clinical effect and safety profile of pegzilarginase in patients with arginase 1 deficiency. causal interaction,unassigned 4,0 3.5.3.1 arginase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33542202&form=6&db=m Novel ARG1 variants identified in a patient with arginase 1 deficiency. causal interaction,unassigned 1,0