3.4.21.B12 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17230566&form=6&db=m Kallikrein 4 is expressed in malignant mesothelioma--further evidence for the histogenetic link between mesothelial and epithelial cells. diagnostic usage,ongoing research,unassigned 3,4,0 3.4.21.B12 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23201139&form=6&db=m Kallikrein-related peptidase 4 (KLK4) mRNA predicts short-term relapse in colorectal adenocarcinoma patients. causal interaction,diagnostic usage,therapeutic application,unassigned 2,3,1,0 3.4.21.B12 Amelogenesis Imperfecta http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15235027&form=6&db=m Mutation in kallikrein 4 causes autosomal recessive hypomaturation amelogenesis imperfecta. causal interaction,unassigned 2,0 3.4.21.B12 Amelogenesis Imperfecta http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16674656&form=6&db=m Human enamel phenotype associated with amelogenesis imperfecta and a kallikrein-4 (g.2142G>A) proteinase mutation. causal interaction,ongoing research,unassigned 3,1,0 3.4.21.B12 Amelogenesis Imperfecta http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18096894&form=6&db=m Premature stop codon in MMP20 causing amelogenesis imperfecta. causal interaction,unassigned 1,0 3.4.21.B12 Amelogenesis Imperfecta http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19578120&form=6&db=m Hypomaturation enamel defects in Klk4 knockout/LacZ knockin mice. causal interaction,unassigned 3,0 3.4.21.B12 Amelogenesis Imperfecta http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19966041&form=6&db=m MMP20 hemopexin domain mutation in amelogenesis imperfecta. unassigned - 3.4.21.B12 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18687310&form=6&db=m Specific increase of human kallikrein 4 mRNA and protein levels in breast cancer stromal cells. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,4,0 3.4.21.B12 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22148895&form=6&db=m Kallikrein-related peptidase signaling in colon carcinoma cells: Targeting proteinase-activated receptors (PARs). causal interaction,ongoing research,therapeutic application,unassigned 1,3,2,0 3.4.21.B12 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31829025&form=6&db=m MiR-378a-5p inhibits angiogenesis of oral squamous cell carcinoma by targeting KLK4. causal interaction,unassigned 4,0 3.4.21.B12 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11489814&form=6&db=m Human kallikrein 4 (KLK4) is highly expressed in serous ovarian carcinomas. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,2,0 3.4.21.B12 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15716231&form=6&db=m Kallikrein 4 expression is up-regulated in epithelial ovarian carcinoma cells in effusions. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,4,0 3.4.21.B12 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24854539&form=6&db=m Low mRNA expression levels of kallikrein-related peptidase 4 (KLK4) predict short-term relapse in patients with laryngeal squamous cell carcinoma. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,3,1 3.4.21.B12 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28743213&form=6&db=m Kallikrein-related peptidase 4 contributes to the tumor metastasis of oral squamous cell carcinoma. causal interaction,unassigned 4,0 3.4.21.B12 Carcinoma, Ovarian Epithelial http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15716231&form=6&db=m Kallikrein 4 expression is up-regulated in epithelial ovarian carcinoma cells in effusions. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,4,0 3.4.21.B12 Carcinoma, Squamous Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33841682&form=6&db=m Elevated levels of both microRNA 378 (miR-378) and kallikrein-related peptidase 4 (KLK4) mRNA are associated with an unfavorable prognosis in triple-negative breast cancer. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,3,0 3.4.21.B12 Colonic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20056842&form=6&db=m Kallikrein-related peptidase 4: a new activator of the aberrantly expressed protease-activated receptor 1 in colon cancer cells. ongoing research,unassigned 4,0 3.4.21.B12 Endometrial Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11344246&form=6&db=m Kallikrein 4 (KLK4), a new member of the human kallikrein gene family is up-regulated by estrogen and progesterone in the human endometrial cancer cell line, KLE. ongoing research,unassigned 3,0 3.4.21.B12 Endometrial Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20009893&form=6&db=m Kallikrein 4 overexpression in endometrial carcinoma and upregulation by estrogen via mitogen-activated protein kinase signal pathway. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,3,1 3.4.21.B12 Endometriosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32400148&form=6&db=m Kallikrein-related peptidase 4 promotes migration and invasion of endometrial stromal cells in endometriosis by inducing epithelial-mesenchymal transition. causal interaction,ongoing research,unassigned 4,4,0 3.4.21.B12 Hepatitis C http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17177967&form=6&db=m Severe fibrosis in hepatitis C virus-infected patients is associated with increased activity of the mannan-binding lectin (MBL)/MBL-associated serine protease 1 (MASP-1) complex. causal interaction,unassigned 3,0 3.4.21.B12 Hepatitis C http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23841802&form=6&db=m Mannan binding lectin-associated serine protease 1 is induced by hepatitis C virus infection and activates human hepatic stellate cells. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,3,1 3.4.21.B12 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23966554&form=6&db=m Identification of a Highly Antigenic Region of Subtilisin-Like Serine Protease 1 for Serodiagnosis of Neospora caninum Infection. causal interaction,unassigned 2,0 3.4.21.B12 Leukoencephalopathies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32101834&form=6&db=m A Case of Cerebral Small Vessel Disease Related to a Heterozygous Nonsense Mutation in HTRA1. causal interaction,unassigned 3,0 3.4.21.B12 Leukoencephalopathies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32445900&form=6&db=m Genetically Confirmed CARASIL: Case Report with Novel HTRA1 Mutation and Literature Review. causal interaction,unassigned 3,0 3.4.21.B12 Lupus Nephritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26546590&form=6&db=m Micro-RNA analysis of renal biopsies in human lupus nephritis demonstrates up-regulated miR-422a driving reduction of kallikrein-related peptidase 4. ongoing research,unassigned 2,0 3.4.21.B12 Lupus Nephritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26614269&form=6&db=m Role of miR-422a and kallikrein-related peptidase 4 implicated in the development of lupus nephritis. Do we work in this direction? unassigned - 3.4.21.B12 Mesothelioma, Malignant http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17230566&form=6&db=m Kallikrein 4 is expressed in malignant mesothelioma--further evidence for the histogenetic link between mesothelial and epithelial cells. diagnostic usage,ongoing research,unassigned 3,4,0 3.4.21.B12 Mouth Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25862839&form=6&db=m Clinical significance of kallikrein-related peptidase-4 in oral cancer. causal interaction,diagnostic usage,ongoing research,unassigned 4,2,4,0 3.4.21.B12 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27378148&form=6&db=m Prostate Cancer-Associated Kallikrein-Related Peptidase 4 Activates Matrix Metalloproteinase-1 and Thrombospondin-1. causal interaction,diagnostic usage,unassigned 3,4,0 3.4.21.B12 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28743213&form=6&db=m Kallikrein-related peptidase 4 contributes to the tumor metastasis of oral squamous cell carcinoma. causal interaction,unassigned 4,0 3.4.21.B12 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31829025&form=6&db=m MiR-378a-5p inhibits angiogenesis of oral squamous cell carcinoma by targeting KLK4. causal interaction,unassigned 4,0 3.4.21.B12 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34373558&form=6&db=m A KLK4 proteinase substrate capture approach to antagonize PAR1. causal interaction,unassigned 3,0 3.4.21.B12 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17221837&form=6&db=m Kallikrein 4 is a potential mediator of cellular interactions between cancer cells and osteoblasts in metastatic prostate cancer. causal interaction,diagnostic usage,ongoing research,unassigned 3,3,3,0 3.4.21.B12 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17230566&form=6&db=m Kallikrein 4 is expressed in malignant mesothelioma--further evidence for the histogenetic link between mesothelial and epithelial cells. diagnostic usage,ongoing research,unassigned 3,4,0 3.4.21.B12 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17303231&form=6&db=m Ovarian cancer specific kallikrein profile in effusions. causal interaction,diagnostic usage,unassigned 1,4,0 3.4.21.B12 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18308730&form=6&db=m Kallikrein-related peptidase 4 (KLK4) initiates intracellular signaling via protease-activated receptors (PARs). KLK4 and PAR-2 are co-expressed during prostate cancer progression. causal interaction,unassigned 2,0 3.4.21.B12 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19147544&form=6&db=m Direct progesterone receptor and indirect androgen receptor interactions with the kallikrein-related peptidase 4 gene promoter in breast and prostate cancer. causal interaction,diagnostic usage,ongoing research,unassigned 3,3,4,0 3.4.21.B12 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21520157&form=6&db=m Kallikrein-related peptidase 4 gene (KLK4) in prostate tumors: Quantitative expression analysis and evaluation of its clinical significance. causal interaction,diagnostic usage,unassigned 4,4,0 3.4.21.B12 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21912076&form=6&db=m Comparative Temporospatial Expression Profiling of Murine Amelotin Protein during Amelogenesis. unassigned - 3.4.21.B12 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22148895&form=6&db=m Kallikrein-related peptidase signaling in colon carcinoma cells: Targeting proteinase-activated receptors (PARs). causal interaction,ongoing research,therapeutic application,unassigned 1,3,2,0 3.4.21.B12 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28454262&form=6&db=m Aberrant KLK4 gene promoter hypomethylation in pediatric hepatoblastomas. therapeutic application,unassigned 1,0 3.4.21.B12 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28743213&form=6&db=m Kallikrein-related peptidase 4 contributes to the tumor metastasis of oral squamous cell carcinoma. causal interaction,unassigned 4,0 3.4.21.B12 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30811511&form=6&db=m Characterization of kallikrein-related peptidase 4 (KLK4) mRNA expression in tumor tissue of advanced high-grade serous ovarian cancer patients. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,1 3.4.21.B12 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31829025&form=6&db=m MiR-378a-5p inhibits angiogenesis of oral squamous cell carcinoma by targeting KLK4. causal interaction,unassigned 4,0 3.4.21.B12 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32400148&form=6&db=m Kallikrein-related peptidase 4 promotes migration and invasion of endometrial stromal cells in endometriosis by inducing epithelial-mesenchymal transition. causal interaction,ongoing research,unassigned 4,4,0 3.4.21.B12 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33255452&form=6&db=m KLK4 Induces Anti-Tumor Effects in Human Xenograft Mouse Models of Orthotopic and Metastatic Prostate Cancer. causal interaction,therapeutic application,unassigned 4,1,0 3.4.21.B12 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33841682&form=6&db=m Elevated levels of both microRNA 378 (miR-378) and kallikrein-related peptidase 4 (KLK4) mRNA are associated with an unfavorable prognosis in triple-negative breast cancer. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,3,0 3.4.21.B12 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34373558&form=6&db=m A KLK4 proteinase substrate capture approach to antagonize PAR1. causal interaction,unassigned 3,0 3.4.21.B12 Odontogenic Tumors http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27601817&form=6&db=m Kallikrein 4 and matrix metalloproteinase-20 immunoexpression in malignant, benign and infiltrative odontogenic tumors. causal interaction,ongoing research,unassigned 4,2,0 3.4.21.B12 Ovarian Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15262123&form=6&db=m Kallikrein 4 is associated with paclitaxel resistance in ovarian cancer. causal interaction,diagnostic usage,unassigned 4,1,0 3.4.21.B12 Ovarian Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17303231&form=6&db=m Ovarian cancer specific kallikrein profile in effusions. causal interaction,diagnostic usage,unassigned 1,4,0 3.4.21.B12 Ovarian Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23451143&form=6&db=m Paclitaxel resistance and multicellular spheroid formation are induced by kallikrein-related peptidase 4 in serous ovarian cancer cells in an ascites mimicking microenvironment. causal interaction,unassigned 1,0 3.4.21.B12 Ovarian Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30811511&form=6&db=m Characterization of kallikrein-related peptidase 4 (KLK4) mRNA expression in tumor tissue of advanced high-grade serous ovarian cancer patients. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,1 3.4.21.B12 Pancreatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26546433&form=6&db=m PRSS1 mutations and the proteinase/antiproteinase imbalance in the pathogenesis of pancreatic cancer. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,3,0 3.4.21.B12 Pancreatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21415673&form=6&db=m High Incidence of PRSS1 and SPINK1 Mutations in Korean Children With Acute Recurrent and Chronic Pancreatitis. diagnostic usage,ongoing research,unassigned 2,2,0 3.4.21.B12 Pancreatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23503650&form=6&db=m Hereditary pancreatitis for the endoscopist. causal interaction,diagnostic usage,unassigned 4,3,0 3.4.21.B12 Pancreatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24458023&form=6&db=m Human cationic trypsinogen (PRSS1) variants and chronic pancreatitis. diagnostic usage,ongoing research,unassigned 1,4,0 3.4.21.B12 Pancreatitis, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21415673&form=6&db=m High Incidence of PRSS1 and SPINK1 Mutations in Korean Children With Acute Recurrent and Chronic Pancreatitis. diagnostic usage,ongoing research,unassigned 2,2,0 3.4.21.B12 Pancreatitis, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24458023&form=6&db=m Human cationic trypsinogen (PRSS1) variants and chronic pancreatitis. diagnostic usage,ongoing research,unassigned 1,4,0 3.4.21.B12 Pancreatitis, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31751559&form=6&db=m Mutation That Promotes Activation of Trypsinogen Increases Severity of Secretagogue-Induced Pancreatitis in Mice. causal interaction,unassigned 1,0 3.4.21.B12 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12142379&form=6&db=m Detection of human kallikrein 4 in healthy and cancerous prostatic tissues by immunofluorometry and immunohistochemistry. diagnostic usage,ongoing research,unassigned 1,2,0 3.4.21.B12 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15059887&form=6&db=m Kallikrein 4 is a predominantly nuclear protein and is overexpressed in prostate cancer. causal interaction,diagnostic usage,unassigned 3,4,0 3.4.21.B12 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16172196&form=6&db=m Kallikrein 4 (hK4) and prostate-specific antigen (PSA) are associated with the loss of E-cadherin and an epithelial-mesenchymal transition (EMT)-like effect in prostate cancer cells. causal interaction,diagnostic usage,therapeutic application,unassigned 4,3,1,0 3.4.21.B12 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16322328&form=6&db=m Compartmentalized expression of kallikrein 4 (KLK4/hK4) isoforms in prostate cancer: nuclear, cytoplasmic and secreted forms. causal interaction,diagnostic usage,unassigned 3,4,0 3.4.21.B12 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17221837&form=6&db=m Kallikrein 4 is a potential mediator of cellular interactions between cancer cells and osteoblasts in metastatic prostate cancer. causal interaction,diagnostic usage,ongoing research,unassigned 3,3,3,0 3.4.21.B12 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17545602&form=6&db=m Kallikrein 4 is a proliferative factor that is overexpressed in prostate cancer. causal interaction,diagnostic usage,unassigned 4,3,0 3.4.21.B12 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17587816&form=6&db=m Epithelial-mesenchymal transition in prostate cancer and the potential role of kallikrein serine proteases. causal interaction,diagnostic usage,unassigned 2,3,0 3.4.21.B12 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18308730&form=6&db=m Kallikrein-related peptidase 4 (KLK4) initiates intracellular signaling via protease-activated receptors (PARs). KLK4 and PAR-2 are co-expressed during prostate cancer progression. causal interaction,unassigned 2,0 3.4.21.B12 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19147544&form=6&db=m Direct progesterone receptor and indirect androgen receptor interactions with the kallikrein-related peptidase 4 gene promoter in breast and prostate cancer. causal interaction,diagnostic usage,ongoing research,unassigned 3,3,4,0 3.4.21.B12 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19549601&form=6&db=m Substrate-guided design of a potent and selective kallikrein-related peptidase inhibitor for kallikrein 4. causal interaction,therapeutic application,unassigned 3,4,0 3.4.21.B12 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19795418&form=6&db=m Kallikrein-related peptidase-4 initiates tumor-stroma interactions in prostate cancer through protease-activated receptor-1. diagnostic usage,unassigned 3,0 3.4.21.B12 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20180634&form=6&db=m Polyclonal antibodies against kallikrein-related peptidase 4 (KLK4): immunohistochemical assessment of KLK4 expression in healthy tissues and prostate cancer. diagnostic usage,ongoing research,unassigned 4,3,0 3.4.21.B12 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21556330&form=6&db=m Mastering the canonical loop of serine protease inhibitors: enhancing potency by optimising the internal hydrogen bond network. causal interaction,therapeutic application,unassigned 3,4,0 3.4.21.B12 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21874303&form=6&db=m Human kallikrein 4 signal peptide induces cytotoxic T cell responses in healthy donors and prostate cancer patients. diagnostic usage,ongoing research,unassigned 4,3,0 3.4.21.B12 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25724897&form=6&db=m Murine, but not human, ephrin-B2 can be efficiently cleaved by the serine protease kallikrein-4: Implications for xenograft models of human prostate cancer. causal interaction,diagnostic usage,unassigned 3,1,0 3.4.21.B12 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25862631&form=6&db=m Expression of human kallikrein 1-related peptidase 4 (KLK4) and MET phosphorylation in prostate cancer tissue: immunohistochemical analysis. causal interaction,diagnostic usage,ongoing research,unassigned 3,3,4,0 3.4.21.B12 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27378148&form=6&db=m Prostate Cancer-Associated Kallikrein-Related Peptidase 4 Activates Matrix Metalloproteinase-1 and Thrombospondin-1. causal interaction,diagnostic usage,unassigned 3,4,0 3.4.21.B12 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30613336&form=6&db=m Potent, Selective, and Cell-Penetrating Inhibitors of Kallikrein-Related Peptidase 4 Based on the Cyclic Peptide MCoTI-II. causal interaction,unassigned 3,0 3.4.21.B12 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31397325&form=6&db=m Crystal structure of the inhibitor-free form of the serine protease kallikrein-4. causal interaction,diagnostic usage,unassigned 4,2,0 3.4.21.B12 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33255452&form=6&db=m KLK4 Induces Anti-Tumor Effects in Human Xenograft Mouse Models of Orthotopic and Metastatic Prostate Cancer. causal interaction,therapeutic application,unassigned 4,1,0 3.4.21.B12 Sepsis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24667622&form=6&db=m Identification of Potential Biomarkers by Serum Proteomics Analysis in Rats With Sepsis. causal interaction,diagnostic usage,therapeutic application,unassigned 2,2,1,0 3.4.21.B12 Squamous Cell Carcinoma of Head and Neck http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24854539&form=6&db=m Low mRNA expression levels of kallikrein-related peptidase 4 (KLK4) predict short-term relapse in patients with laryngeal squamous cell carcinoma. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,3,1 3.4.21.B12 Squamous Cell Carcinoma of Head and Neck http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28743213&form=6&db=m Kallikrein-related peptidase 4 contributes to the tumor metastasis of oral squamous cell carcinoma. causal interaction,unassigned 4,0 3.4.21.B12 Triple Negative Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28755528&form=6&db=m Tissue kallikrein-related peptidase 4 (KLK4), a novel biomarker in triple-negative breast cancer. ongoing research,therapeutic application,unassigned 2,1,0 3.4.21.B12 Triple Negative Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33841682&form=6&db=m Elevated levels of both microRNA 378 (miR-378) and kallikrein-related peptidase 4 (KLK4) mRNA are associated with an unfavorable prognosis in triple-negative breast cancer. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,3,0 3.4.21.B12 Virus Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23841802&form=6&db=m Mannan binding lectin-associated serine protease 1 is induced by hepatitis C virus infection and activates human hepatic stellate cells. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,3,1