3.4.21.9 Acrodermatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24940857&form=6&db=m Congenital diseases of the gastrointestinal tract. unassigned - 3.4.21.9 Albuminuria http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33351150&form=6&db=m Enteropeptidase inhibitor SCO-792 effectively prevents kidney function decline and fibrosis in a rat model of chronic kidney disease. causal interaction,ongoing research,therapeutic application,unassigned 3,4,4,0 3.4.21.9 alpha,alpha-trehalase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=615485&form=6&db=m Possibilities for the cytochemical diagnosis of enzymopathies. causal interaction,therapeutic application,unassigned 1,1,0 3.4.21.9 Amyotrophic Lateral Sclerosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34396108&form=6&db=m Analysis of circulating protein aggregates as a route of investigation into neurodegenerative disorders. unassigned - 3.4.21.9 Anemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=961414&form=6&db=m Intestinal enterokinase deficiency. causal interaction,unassigned 4,0 3.4.21.9 Arrhythmogenic Right Ventricular Dysplasia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2735884&form=6&db=m Arrhythmogenic right ventricular dysplasia in a child with congenital enteropeptidase deficiency and hypogammaglobulinaemia. causal interaction,unassigned 4,0 3.4.21.9 Biliary Atresia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4856586&form=6&db=m Role of bile acids in the activation of trypsinogen by enterokinase: disturbance of trypsinogen activation in patients with intrahepatic biliary atresia. causal interaction,unassigned 2,0 3.4.21.9 Brain Injuries, Traumatic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21278408&form=6&db=m In vivo monitoring of neuronal loss in traumatic brain injury: a microdialysis study. therapeutic application,unassigned 1,0 3.4.21.9 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7670383&form=6&db=m The SEA module: a new extracellular domain associated with O-glycosylation. ongoing research,unassigned 1,0 3.4.21.9 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32488403&form=6&db=m Unraveling mucin domains in cancer and metastasis: when protectors become predators. ongoing research,unassigned 1,0 3.4.21.9 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=324873&form=6&db=m Immunofluorescent localisation of enterokinase in human small intestine. unassigned - 3.4.21.9 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18062964&form=6&db=m Intracellular co-localization of trypsin-2 and matrix metalloprotease-9: possible proteolytic cascade of trypsin-2, MMP-9 and enterokinase in carcinoma. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,4,2 3.4.21.9 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27270881&form=6&db=m Antithrombin controls tumor migration, invasion and angiogenesis by inhibition of enteropeptidase. causal interaction,ongoing research,therapeutic application,unassigned 4,4,4,0 3.4.21.9 Celiac Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=809741&form=6&db=m The interrelationship of enterokinase and trypsin activities in intractable diarrhea of infancy, celiac disease, and intravenous alimentation. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,2,0 3.4.21.9 Celiac Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=876725&form=6&db=m Mucosal enterokinase activity in pancreatic insufficiency and celiac disease. diagnostic usage,ongoing research,unassigned 3,2,0 3.4.21.9 Celiac Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11467662&form=6&db=m Celiac disease in a patient with a congenital deficiency of intestinal enteropeptidase. causal interaction,unassigned 4,0 3.4.21.9 Cholestasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=750264&form=6&db=m Influence of biliary stasis on enterokinase activity in the rat. causal interaction,ongoing research,unassigned 1,4,0 3.4.21.9 Colitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=13860444&form=6&db=m [Content of enterokinase and pancreatic enzymes in the duodenal juice of patients with chronic colitis and enterocolitis.] causal interaction,diagnostic usage,ongoing research,unassigned 1,2,2,0 3.4.21.9 Congenital Abnormalities http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1147667&form=6&db=m Intestinal enterokinase deficiency. Occurrence in two sibs and age dependency of clinical expression. causal interaction,diagnostic usage,unassigned 4,1,0 3.4.21.9 Cystic Fibrosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=943355&form=6&db=m Enterokinase and trypsin activities in pancreatic insufficiency and diseases of the small intestine. causal interaction,diagnostic usage,ongoing research,unassigned 1,4,2,0 3.4.21.9 Cystic Fibrosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2480820&form=6&db=m Behaviour of serum immunoreactive trypsin after serum activation by enterokinase in normal and cystic fibrosis patients. Evidence of a trypsin-alpha 1-proteinase inhibitor complex in some cystic fibrosis patients. causal interaction,diagnostic usage,unassigned 4,4,0 3.4.21.9 Cystic Fibrosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4527956&form=6&db=m Rapid semiquantitative tests for trypsin and chymotrypsin application to screening for cystic fibrosis, enterokinase deficiency and pancreatic hypoplasia in neonates. diagnostic usage,unassigned 3,0 3.4.21.9 Cystic Fibrosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7044859&form=6&db=m Effect of pancreozymin and secretin on intraluminal enterokinase, trypsin, and chymotrypsin activities of cystic fibrosis and control children. diagnostic usage,ongoing research,unassigned 3,2,0 3.4.21.9 Cysts http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1995487&form=6&db=m Human colon carcinoma, fibrosarcoma and leukemia cell lines produce tumor-associated trypsinogen. causal interaction,ongoing research,unassigned 3,2,0 3.4.21.9 Diabetic Nephropathies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32893449&form=6&db=m Enteropeptidase inhibition improves kidney function in a rat model of diabetic kidney disease. causal interaction,ongoing research,therapeutic application,unassigned 1,4,3,0 3.4.21.9 Diffuse Axonal Injury http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21278408&form=6&db=m In vivo monitoring of neuronal loss in traumatic brain injury: a microdialysis study. therapeutic application,unassigned 1,0 3.4.21.9 Enteritis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3481658&form=6&db=m [Clinical importance of the determination of intestinal dipeptidase and enterokinase activity in patients with chronic enteritis] causal interaction,diagnostic usage,ongoing research,unassigned 1,4,4,0 3.4.21.9 Enterocolitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=13860444&form=6&db=m [Content of enterokinase and pancreatic enzymes in the duodenal juice of patients with chronic colitis and enterocolitis.] causal interaction,diagnostic usage,ongoing research,unassigned 1,2,2,0 3.4.21.9 enteropeptidase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=40607&form=6&db=m The two human trypsinogens. Evidence of complex formation with basic pancreatic trypsin inhibitor-proteolytic activity. diagnostic usage,unassigned 1,0 3.4.21.9 enteropeptidase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=329214&form=6&db=m [Congenital enterokinase deficiency] causal interaction,unassigned 4,0 3.4.21.9 enteropeptidase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=809741&form=6&db=m The interrelationship of enterokinase and trypsin activities in intractable diarrhea of infancy, celiac disease, and intravenous alimentation. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,2,0 3.4.21.9 enteropeptidase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=943355&form=6&db=m Enterokinase and trypsin activities in pancreatic insufficiency and diseases of the small intestine. causal interaction,diagnostic usage,ongoing research,unassigned 1,4,2,0 3.4.21.9 enteropeptidase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=961414&form=6&db=m Intestinal enterokinase deficiency. causal interaction,unassigned 4,0 3.4.21.9 enteropeptidase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1147667&form=6&db=m Intestinal enterokinase deficiency. Occurrence in two sibs and age dependency of clinical expression. causal interaction,diagnostic usage,unassigned 4,1,0 3.4.21.9 enteropeptidase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1178293&form=6&db=m [Proceedings: Enterokinase deficiency] causal interaction,unassigned 3,0 3.4.21.9 enteropeptidase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2735884&form=6&db=m Arrhythmogenic right ventricular dysplasia in a child with congenital enteropeptidase deficiency and hypogammaglobulinaemia. causal interaction,unassigned 4,0 3.4.21.9 enteropeptidase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3068902&form=6&db=m [The current status of the problem of enterokinase deficiency] causal interaction,unassigned 4,0 3.4.21.9 enteropeptidase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4180366&form=6&db=m Intestinal enterokinase deficiency. causal interaction,unassigned 4,0 3.4.21.9 enteropeptidase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4322674&form=6&db=m Malabsorption and growth failure due to intestinal enterokinase deficiency. causal interaction,unassigned 4,0 3.4.21.9 enteropeptidase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4527956&form=6&db=m Rapid semiquantitative tests for trypsin and chymotrypsin application to screening for cystic fibrosis, enterokinase deficiency and pancreatic hypoplasia in neonates. diagnostic usage,unassigned 3,0 3.4.21.9 enteropeptidase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=5473165&form=6&db=m [Trypsinogen pseudo-deficiency caused by congenital enterokinase deficiency. Enzyme study] causal interaction,unassigned 4,0 3.4.21.9 enteropeptidase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=5477679&form=6&db=m Intestinal enterokinase deficiency. A newly-recognized disorder of protein digestion. causal interaction,unassigned 3,0 3.4.21.9 enteropeptidase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=5488678&form=6&db=m [Trypsinogen pseudo-deficiency caused by congenital enterokinase deficiency. Clinical study] causal interaction,unassigned 4,0 3.4.21.9 enteropeptidase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=5579874&form=6&db=m The activation of human pancreatic proteinases. Studies on human pancreatic juice and duodenal juice of four children with intestinal enterokinase deficiency. ongoing research,unassigned 3,0 3.4.21.9 enteropeptidase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6125673&form=6&db=m Intestinal enteropeptidase deficiency associated with exocrine pancreatic insufficiency. causal interaction,unassigned 4,0 3.4.21.9 enteropeptidase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6347801&form=6&db=m Isolated congenital enterokinase deficiency. Recent findings and review of the literature. causal interaction,diagnostic usage,therapeutic application,unassigned 4,3,1,0 3.4.21.9 enteropeptidase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6360788&form=6&db=m Enterokinase deficiency and vitamin B12 absorption. causal interaction,unassigned 4,0 3.4.21.9 enteropeptidase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6384461&form=6&db=m Primary intestinal enteropeptidase deficiency. causal interaction,diagnostic usage,unassigned 4,3,0 3.4.21.9 enteropeptidase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8208733&form=6&db=m Enterokinase. causal interaction,unassigned 4,0 3.4.21.9 enteropeptidase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9645159&form=6&db=m [Congenital enterokinase deficiency] causal interaction,unassigned 4,0 3.4.21.9 enteropeptidase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11467662&form=6&db=m Celiac disease in a patient with a congenital deficiency of intestinal enteropeptidase. causal interaction,unassigned 4,0 3.4.21.9 enteropeptidase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11719902&form=6&db=m Mutations in the proenteropeptidase gene are the molecular cause of congenital enteropeptidase deficiency. causal interaction,unassigned 4,0 3.4.21.9 enteropeptidase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23185382&form=6&db=m Enteropeptidase: a gene associated with a starvation human phenotype and a novel target for obesity treatment. causal interaction,therapeutic application,unassigned 4,4,0 3.4.21.9 enteropeptidase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24725128&form=6&db=m Rare Genetic Diseases with Human Lean and/or Starvation Phenotype Open New Avenues for Obesity and Type II Diabetes Treatment. causal interaction,therapeutic application,unassigned 4,4,0 3.4.21.9 enteropeptidase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24940857&form=6&db=m Congenital diseases of the gastrointestinal tract. unassigned - 3.4.21.9 enteropeptidase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33061943&form=6&db=m Novel Compound Heterozygous TMPRSS15 Gene Variants Cause Enterokinase Deficiency. causal interaction,unassigned 4,0 3.4.21.9 enteropeptidase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34106441&form=6&db=m Enterokinase Deficiency: A Case of Pancreatic Insufficiency. causal interaction,unassigned 4,0 3.4.21.9 Exocrine Pancreatic Insufficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=665628&form=6&db=m Enteropeptidase levels in duodenal juice of normal subjects and patients with gastrointestinal disease. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,2,0 3.4.21.9 Exocrine Pancreatic Insufficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=876725&form=6&db=m Mucosal enterokinase activity in pancreatic insufficiency and celiac disease. diagnostic usage,ongoing research,unassigned 3,2,0 3.4.21.9 Exocrine Pancreatic Insufficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=943355&form=6&db=m Enterokinase and trypsin activities in pancreatic insufficiency and diseases of the small intestine. causal interaction,diagnostic usage,ongoing research,unassigned 1,4,2,0 3.4.21.9 Exocrine Pancreatic Insufficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2962436&form=6&db=m Enteropeptidase (EC 3.4.21.9) in coeliac disease and exocrine pancreatic insufficiency. unassigned - 3.4.21.9 Exocrine Pancreatic Insufficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6125673&form=6&db=m Intestinal enteropeptidase deficiency associated with exocrine pancreatic insufficiency. causal interaction,unassigned 4,0 3.4.21.9 Exocrine Pancreatic Insufficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34106441&form=6&db=m Enterokinase Deficiency: A Case of Pancreatic Insufficiency. causal interaction,unassigned 4,0 3.4.21.9 Fatty Liver http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6336713&form=6&db=m Biliary excretion of enterokinase in rats: studies in alcoholic rats with fatty liver. causal interaction,ongoing research,therapeutic application,unassigned 4,2,1,0 3.4.21.9 Fetal Growth Retardation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6783132&form=6&db=m Effect of intrauterine growth retardation on the activities of fetal intestinal enzymes in rats. causal interaction,therapeutic application,unassigned 1,2,0 3.4.21.9 Foodborne Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=13337725&form=6&db=m [Clinical significance of quantitative determination of enterokinase in feces of patients with food poisoning.] diagnostic usage,ongoing research,unassigned 4,1,0 3.4.21.9 Gastrointestinal Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=665628&form=6&db=m Enteropeptidase levels in duodenal juice of normal subjects and patients with gastrointestinal disease. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,2,0 3.4.21.9 Giardiasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6392841&form=6&db=m [Enterokinase and alkaline phosphatase activity in children with hymenolepiasis and lambliasis] unassigned - 3.4.21.9 Herpes Zoster http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15194491&form=6&db=m Initial characterization of an uromodulin-like 1 gene on human chromosome 21q22.3. ongoing research,unassigned 1,0 3.4.21.9 Hymenolepiasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6392841&form=6&db=m [Enterokinase and alkaline phosphatase activity in children with hymenolepiasis and lambliasis] unassigned - 3.4.21.9 Hypoproteinemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=943355&form=6&db=m Enterokinase and trypsin activities in pancreatic insufficiency and diseases of the small intestine. causal interaction,diagnostic usage,ongoing research,unassigned 1,4,2,0 3.4.21.9 Hypoproteinemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8208733&form=6&db=m Enterokinase. causal interaction,unassigned 4,0 3.4.21.9 Hypoproteinemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19482641&form=6&db=m Enteropeptidase, a type II transmembrane serine protease. causal interaction,therapeutic application,unassigned 4,1,0 3.4.21.9 Hypoproteinemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33061943&form=6&db=m Novel Compound Heterozygous TMPRSS15 Gene Variants Cause Enterokinase Deficiency. causal interaction,unassigned 4,0 3.4.21.9 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10722028&form=6&db=m Neurological damage and duodenopancreatic reflux in the pathogenesis of alcoholic pancreatitis. causal interaction,diagnostic usage,unassigned 1,3,0 3.4.21.9 Infections http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29629340&form=6&db=m Enterokinase Enhances Influenza A Virus Infection by Activating Trypsinogen in Human Cell Lines. causal interaction,ongoing research,unassigned 2,4,0 3.4.21.9 Influenza, Human http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29629340&form=6&db=m Enterokinase Enhances Influenza A Virus Infection by Activating Trypsinogen in Human Cell Lines. causal interaction,ongoing research,unassigned 2,4,0 3.4.21.9 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31144422&form=6&db=m SCO-792, an enteropeptidase inhibitor, improves disease status of diabetes and obesity in mice. causal interaction,ongoing research,therapeutic application,unassigned 1,4,4,0 3.4.21.9 Insulinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32828294&form=6&db=m Synthetic protease-activated class B GPCRs. unassigned - 3.4.21.9 Intestinal Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=5500235&form=6&db=m [Enterokinase and alkaline phosphatase activity in the feces of children in the 1st year of life with acute intestinal diseases and different frequencies of feeding] ongoing research,unassigned 2,0 3.4.21.9 Lactose Intolerance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24940857&form=6&db=m Congenital diseases of the gastrointestinal tract. unassigned - 3.4.21.9 Lung Injury http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10564107&form=6&db=m Trypsin and activation of circulating trypsinogen contribute to pancreatitis-associated lung injury. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,3,1 3.4.21.9 Malabsorption Syndromes http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4434498&form=6&db=m [Histochemical study on enterokinase in duodenal and jejunal biopsies of children with malabsorption syndromes] ongoing research,unassigned 4,0 3.4.21.9 Malnutrition http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=115973&form=6&db=m The effect of early postnatal acquired malnutrition on intestinal growth, disaccharidases and enterokinase. ongoing research,unassigned 1,0 3.4.21.9 Malnutrition http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=809741&form=6&db=m The interrelationship of enterokinase and trypsin activities in intractable diarrhea of infancy, celiac disease, and intravenous alimentation. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,2,0 3.4.21.9 Malnutrition http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2851468&form=6&db=m Interaction of malnutrition and difluoromethylornithine-induced intestinal mucosal damage: degree of severity and subsequent recovery. causal interaction,therapeutic application,unassigned 1,1,0 3.4.21.9 Metabolic Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33033171&form=6&db=m Targeting Enteropeptidase with Reversible Covalent Inhibitors To Achieve Metabolic Benefits. causal interaction,therapeutic application,unassigned 1,4,0 3.4.21.9 Metabolic Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33713780&form=6&db=m Discovery of a novel series of guanidinebenzoates as gut-restricted enteropeptidase and trypsin dual inhibitors for the treatment of metabolic syndrome. causal interaction,therapeutic application,unassigned 3,4,0 3.4.21.9 Muscle Spasticity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11402045&form=6&db=m Recombinant forms of tetanus toxin engineered for examining and exploiting neuronal trafficking pathways. therapeutic application,unassigned 2,0 3.4.21.9 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27270881&form=6&db=m Antithrombin controls tumor migration, invasion and angiogenesis by inhibition of enteropeptidase. causal interaction,ongoing research,therapeutic application,unassigned 4,4,4,0 3.4.21.9 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=665628&form=6&db=m Enteropeptidase levels in duodenal juice of normal subjects and patients with gastrointestinal disease. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,2,0 3.4.21.9 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1995487&form=6&db=m Human colon carcinoma, fibrosarcoma and leukemia cell lines produce tumor-associated trypsinogen. causal interaction,ongoing research,unassigned 3,2,0 3.4.21.9 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9706704&form=6&db=m High-level production of human growth hormone in Escherichia coli by a simple recombinant process. ongoing research,therapeutic application,unassigned 2,1,0 3.4.21.9 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10348909&form=6&db=m Expression of trypsin in human cancer cell lines and cancer tissues and its tight binding to soluble form of Alzheimer amyloid precursor protein in culture. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,4,1 3.4.21.9 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12907431&form=6&db=m Expression of enteropeptidase in differentiated enterocytes, goblet cells, and the tumor cells in human duodenum. causal interaction,ongoing research,unassigned 2,4,0 3.4.21.9 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20551595&form=6&db=m The trail of my studies on glycoproteins from enterokinase to tumor markers. diagnostic usage,ongoing research,unassigned 2,3,0 3.4.21.9 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27270881&form=6&db=m Antithrombin controls tumor migration, invasion and angiogenesis by inhibition of enteropeptidase. causal interaction,ongoing research,therapeutic application,unassigned 4,4,4,0 3.4.21.9 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29506820&form=6&db=m Tandem repeated expression of lunasin gene in Pichia pastoris and its anti-inflammatory activity in vitro. unassigned - 3.4.21.9 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32488403&form=6&db=m Unraveling mucin domains in cancer and metastasis: when protectors become predators. ongoing research,unassigned 1,0 3.4.21.9 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33511360&form=6&db=m Enzymatic Noncovalent Synthesis for Mitochondrial Genetic Engineering of Cancer Cells. unassigned - 3.4.21.9 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23185382&form=6&db=m Enteropeptidase: a gene associated with a starvation human phenotype and a novel target for obesity treatment. causal interaction,therapeutic application,unassigned 4,4,0 3.4.21.9 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24725128&form=6&db=m Rare Genetic Diseases with Human Lean and/or Starvation Phenotype Open New Avenues for Obesity and Type II Diabetes Treatment. causal interaction,therapeutic application,unassigned 4,4,0 3.4.21.9 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31144422&form=6&db=m SCO-792, an enteropeptidase inhibitor, improves disease status of diabetes and obesity in mice. causal interaction,ongoing research,therapeutic application,unassigned 1,4,4,0 3.4.21.9 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32893449&form=6&db=m Enteropeptidase inhibition improves kidney function in a rat model of diabetic kidney disease. causal interaction,ongoing research,therapeutic application,unassigned 1,4,3,0 3.4.21.9 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33276106&form=6&db=m Enteropeptidase inhibition improves obesity by modulating gut microbiota composition and enterobacterial metabolites in diet-induced obese mice. causal interaction,ongoing research,therapeutic application,unassigned 4,2,4,0 3.4.21.9 Obesity http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33351150&form=6&db=m Enteropeptidase inhibitor SCO-792 effectively prevents kidney function decline and fibrosis in a rat model of chronic kidney disease. causal interaction,ongoing research,therapeutic application,unassigned 3,4,4,0 3.4.21.9 Pancreatic Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2068865&form=6&db=m [Isoelectric focusing of pure human pancreatic juice. 1. Examination of patients with and without pancreatic diseases] diagnostic usage,unassigned 3,0 3.4.21.9 Pancreatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=665628&form=6&db=m Enteropeptidase levels in duodenal juice of normal subjects and patients with gastrointestinal disease. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,2,0 3.4.21.9 Pancreatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=40607&form=6&db=m The two human trypsinogens. Evidence of complex formation with basic pancreatic trypsin inhibitor-proteolytic activity. diagnostic usage,unassigned 1,0 3.4.21.9 Pancreatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=316652&form=6&db=m Enterokinase induced pancreatitis: its prevention with Trasylol and soybean trypsin inhibitor. therapeutic application,unassigned 4,0 3.4.21.9 Pancreatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=842525&form=6&db=m Pancreatitis following the intraductal injection of partially purified enterokinase in dogs. ongoing research,therapeutic application,unassigned 2,2,0 3.4.21.9 Pancreatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3548876&form=6&db=m Intraduct enterokinase is lethal in rats with experimental bile-salt pancreatitis. causal interaction,ongoing research,therapeutic application,unassigned 3,1,3,0 3.4.21.9 Pancreatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3859917&form=6&db=m Pancreatic duct and microvascular permeability to macromolecules. The relation to acute pancreatitis. diagnostic usage,ongoing research,therapeutic application,unassigned 3,4,1,0 3.4.21.9 Pancreatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3905074&form=6&db=m The generation of lysolecithin by enterokinase in trypsinogen prophospholipase A2 lecithin mixtures, and its relevance to the pathogenesis of acute necrotising pancreatitis. causal interaction,diagnostic usage,therapeutic application,unassigned 3,1,2,0 3.4.21.9 Pancreatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4659909&form=6&db=m [Change in the enterokinase and alkaline phosphatase activity in the duodenal contents in acute experimental pancreatitis in dogs] diagnostic usage,ongoing research,therapeutic application,unassigned 3,3,1,0 3.4.21.9 Pancreatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6336713&form=6&db=m Biliary excretion of enterokinase in rats: studies in alcoholic rats with fatty liver. causal interaction,ongoing research,therapeutic application,unassigned 4,2,1,0 3.4.21.9 Pancreatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6383663&form=6&db=m Catalytically active enterokinase in human bile. causal interaction,unassigned 1,0 3.4.21.9 Pancreatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7479669&form=6&db=m Therapeutic regimens in acute experimental pancreatitis in rats: effects of a protease inhibitor, a beta-agonist, and antibiotics. diagnostic usage,ongoing research,therapeutic application,unassigned 4,4,4,0 3.4.21.9 Pancreatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8079180&form=6&db=m Interstitial protease activation is the central event in progression to necrotizing pancreatitis. causal interaction,ongoing research,therapeutic application,unassigned 4,1,1,0 3.4.21.9 Pancreatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8208733&form=6&db=m Enterokinase. causal interaction,unassigned 4,0 3.4.21.9 Pancreatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8851477&form=6&db=m A model of experimental acute necrotizing pancreatitis. causal interaction,unassigned 2,0 3.4.21.9 Pancreatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9361087&form=6&db=m Change of pancreatic enzymes, pancreatic stone protein (PSP), and plasma alpha(2)-macroglobulin-trypsin complex-like substance (MTLS) in the activation of pancreatic juice. diagnostic usage,ongoing research,unassigned 3,3,0 3.4.21.9 Pancreatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10203084&form=6&db=m Influence of zero-balanced hemofiltration on the course of severe experimental pancreatitis in pigs. diagnostic usage,ongoing research,therapeutic application,unassigned 3,1,2,0 3.4.21.9 Pancreatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10564107&form=6&db=m Trypsin and activation of circulating trypsinogen contribute to pancreatitis-associated lung injury. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,3,1 3.4.21.9 Pancreatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10691375&form=6&db=m Enterokinase in cerulein pancreatitis. unassigned - 3.4.21.9 Pancreatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10722028&form=6&db=m Neurological damage and duodenopancreatic reflux in the pathogenesis of alcoholic pancreatitis. causal interaction,diagnostic usage,unassigned 1,3,0 3.4.21.9 Pancreatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10809293&form=6&db=m Bradykinin B2-receptor antagonism attenuates fatal cardiocirculatory breakdown induced by severe experimental pancreatitis. unassigned - 3.4.21.9 Pancreatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11445702&form=6&db=m Attenuation of sepsis-related immunoparalysis by continuous veno-venous hemofiltration in experimental porcine pancreatitis. diagnostic usage,ongoing research,unassigned 3,1,0 3.4.21.9 Pancreatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12371983&form=6&db=m Impact of different modalities of continuous venovenous hemofiltration on sepsis-induced alterations in experimental pancreatitis. ongoing research,unassigned 2,0 3.4.21.9 Pancreatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12577145&form=6&db=m Somatosensory evoked potentials as predictor of systemic inflammatory response syndrome in pigs? unassigned - 3.4.21.9 Pancreatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12698555&form=6&db=m [Hydrolysis by enteropeptidase of nonspecific (model) peptide sequences and possible physiological role of this phenomenon] unassigned - 3.4.21.9 Pancreatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17723883&form=6&db=m Enterokinase induces severe necrosis and rapid mortality in cerulein pancreatitis: characterization of a novel noninvasive rat model of necro-hemorrhagic pancreatitis. ongoing research,therapeutic application,unassigned 2,1,0 3.4.21.9 Pancreatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18516442&form=6&db=m Methylene blue improves hemodynamic shock but increases lipoperoxidation in severe acute pancreatitis pig model. causal interaction,therapeutic application,unassigned 1,2,0 3.4.21.9 Pancreatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25961820&form=6&db=m Loss of Bace1 in mice does not alter the severity of caerulein induced pancreatitis. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,4,4,2 3.4.21.9 Pancreatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33833935&form=6&db=m Role of SCO-792, A Novel Enteropeptidase Inhibitor, In the Prevention of Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis. causal interaction,therapeutic application,unassigned 3,4,0 3.4.21.9 Pancreatitis, Acute Hemorrhagic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=84661&form=6&db=m Effect of chlorophyll-a, fluorouracil, and pituitrin on experimental acute pancreatitis. causal interaction,unassigned 2,0 3.4.21.9 Pancreatitis, Acute Hemorrhagic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9629507&form=6&db=m Lexipafant fails to improve survival in severe necrotizing pancreatitis in rats. causal interaction,diagnostic usage,ongoing research,therapeutic application 1,1,1,2 3.4.21.9 Pancreatitis, Acute Necrotizing http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3548876&form=6&db=m Intraduct enterokinase is lethal in rats with experimental bile-salt pancreatitis. causal interaction,ongoing research,therapeutic application,unassigned 3,1,3,0 3.4.21.9 Pancreatitis, Alcoholic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=665628&form=6&db=m Enteropeptidase levels in duodenal juice of normal subjects and patients with gastrointestinal disease. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,2,0 3.4.21.9 Pancreatitis, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2068865&form=6&db=m [Isoelectric focusing of pure human pancreatic juice. 1. Examination of patients with and without pancreatic diseases] diagnostic usage,unassigned 3,0 3.4.21.9 Pancreatitis, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10722028&form=6&db=m Neurological damage and duodenopancreatic reflux in the pathogenesis of alcoholic pancreatitis. causal interaction,diagnostic usage,unassigned 1,3,0 3.4.21.9 Pancreatitis, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19482641&form=6&db=m Enteropeptidase, a type II transmembrane serine protease. causal interaction,therapeutic application,unassigned 4,1,0 3.4.21.9 Paralysis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11402045&form=6&db=m Recombinant forms of tetanus toxin engineered for examining and exploiting neuronal trafficking pathways. therapeutic application,unassigned 2,0 3.4.21.9 Protein-Energy Malnutrition http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3124316&form=6&db=m Enterokinase and disaccharidase activities of the small intestinal mucosa in infants with protein-energy malnutrition and in normal infants. diagnostic usage,ongoing research,unassigned 1,2,0 3.4.21.9 Renal Insufficiency, Chronic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33351150&form=6&db=m Enteropeptidase inhibitor SCO-792 effectively prevents kidney function decline and fibrosis in a rat model of chronic kidney disease. causal interaction,ongoing research,therapeutic application,unassigned 3,4,4,0 3.4.21.9 Skin Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=5563588&form=6&db=m [Enterokinase activity of the intestine in several skin diseases] therapeutic application,unassigned 1,0 3.4.21.9 Squamous Cell Carcinoma of Head and Neck http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18062964&form=6&db=m Intracellular co-localization of trypsin-2 and matrix metalloprotease-9: possible proteolytic cascade of trypsin-2, MMP-9 and enterokinase in carcinoma. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,4,2 3.4.21.9 Starvation http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23185382&form=6&db=m Enteropeptidase: a gene associated with a starvation human phenotype and a novel target for obesity treatment. causal interaction,therapeutic application,unassigned 4,4,0 3.4.21.9 Steatorrhea http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8208733&form=6&db=m Enterokinase. causal interaction,unassigned 4,0 3.4.21.9 Stomach Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10348909&form=6&db=m Expression of trypsin in human cancer cell lines and cancer tissues and its tight binding to soluble form of Alzheimer amyloid precursor protein in culture. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,4,1 3.4.21.9 Thrombosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23313448&form=6&db=m cDNA cloning of a snake venom metalloproteinase from the eastern diamondback rattlesnake (Crotalus adamanteus), and the expression of its disintegrin domain with anti-platelet effects. diagnostic usage,unassigned 1,0 3.4.21.9 Trichuriasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2779491&form=6&db=m [Microparasitocenosis of the intestines and the activity of intestinal enzymes in patients with trichocephaliasis during treatment] therapeutic application,unassigned 1,0 3.4.21.9 Virus Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29629340&form=6&db=m Enterokinase Enhances Influenza A Virus Infection by Activating Trypsinogen in Human Cell Lines. causal interaction,ongoing research,unassigned 2,4,0